Clinical Value of Predictive Nursing Intervention on Deep Venous Thrombosis of Lower Extremities after Cesarean Section

[Objectives]To explore the clinical nursing value of predictive nursing intervention in patients with deep venous thrombosis of lower extremities after cesarean section.[Methods]From December 2022 to April 2023,105 pregnant and lying-in women who were hospitalized in the Gynecology Department of Pingquan Hospital and underwent cesarean section and met the inclusion criteria were included as the study objects.According to the medical records,they were divided into observation group(n=52 cases)and control group(n=53 cases).The clinical experimental subjects were divided into two groups.One group was the control group with routine nursing,and the other group was the observation group with predictive nursing intervention.The number of cases of deep venous thrombosis of lower extremities in the two groups was recorded to evaluate the clinical value.[Results]The incidence of deep venous thrombosis of lower extremities in the two groups after cesarean section was compared,and it was suggested that the incidence of the observation group was lower than that of the control group(P<0.05).[Conclusions]Special predictive nursing intervention can greatly reduce the incidence of deep venous thrombosis of lower extremities after cesarean section,improve nursing satisfaction,and improve clinical efficacy,which is worthy of recommendation.

Pitfalls and sources of error of color duplex ultrasonography in detecting deep vein thrombosis of proximal lower extremities

Purpose To analyze the sources of errors and discuss the techniques to eliminate pitfalls in detecting deep vein thrombosis (DVT) of the proximal lower extremities with color duplex ultrasonography (CDUS). Methods Sixty-eight cases with initial and repeat venous CDUS of the proximal lower extremities were retrospectively reviewed. The repeat was done within 24 hours after initial CDUS scanning. Comparing repeated images to initial ones, the pitfalls and sources of error in CDUS of the proximal lower extremities were discussed. Results In total 68 repeat studies, there were 62 results as same as initials and 4 cases of false negative DVT and 2 cases of false positive DVT. Conclusion Venous CDUS in detecting DVT is observer dependent. Some pitfalls and errors can be eliminated and corrected with proper scan techniques. CDUS is the most valuable imaging modality for assessing suspected DVT in the proximal lower extremities.

Predictive Value of Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation, and Systemic Inflammation Response Index in Lower Extremity Deep Venous Thrombosis Following Severe Trauma

Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lower extremity deep venous thrombosis(LEDVT)in a severely traumatized population and to evaluate their predictive value for LEDVT.Methods This was a retrospective,single-center observational study.All subjects were severely traumatized patients who were admitted to the Traumatic Intensive Care Unit from January 2021 to May 2024.Based on Doppler ultrasound findings of both lower extremities from the time of injury to 30 days post-injury,patients who developed LEDVT were enrolled in the LEDVT group,and those who did not develop LEDVT were enrolled in the NLEDVT group.Demographic,clinical,and laboratory data were collected upon admission.Multivariable logistic regression analysis was performed to identify risk factors for LEDVT.Receiver operating characteristic(ROC)curve was used to evaluate the overall fit of the final model.Results There were 56 patients enrolled in the LEDVT group and 81 patients in the NLEDVT group.Age,Aggregate Index of Systemic Inflammation(AISI),Systemic Inflammation Response Index(SIRI),ICU length of stay,and albumin were identified as independent risk factors for LEDVT(all P<0.05).The area under their ROC curves were 0.604,0.657,0.694,0.668,and 0.405,respectively.Combined model for early clinical prediction of LEDVT in severely traumatized patients by age,SIRI,AISI,and albumin resulted in an area under the ROC curve of 0.805(95%CI:0.73-0.88,SE=0.037).Conclusion The combination of age,SIRI,AISI,and albumin has a predictive value for LEDVT in severely traumatized patients.

Efficacy of percutaneous mechanical thrombus removal in acute lower extremity deep venous thrombosis

BACKGROUND Acute lower extremity deep venous thrombosis(LEDVT)is a common vascular emergency with significant morbidity risks,including post-thrombotic syndrome(PTS)and pulmonary embolism.Traditional treatments like catheter-directed thrombolysis(CDT)often result in variable success rates and complications.AIM To investigate the therapeutic efficacy of percutaneous mechanical thrombus removal in acute LEDVT.METHODS A retrospective analysis was performed to examine 58 hospitalised patients with acute LEDVT between August 2019 and August 2022.The patients were categorised into the percutaneous mechanical thrombectomy(PMT)group(n=24)and CDT group(n=32).The follow-up,safety and treatment outcomes were compared between the two groups.The main observational indexes were venous patency score,thrombus removal effect,complications,hospitalisation duration and PTS.RESULTS The venous patency score was 9.04±1.40 in the PMT group and 8.81±1.60 in the CDT group,and the thrombus clearance rate was 100%in both groups.The complication rate was 8.33%in the PMT group and 34.84%in the CDT group,and the difference was statistically significant(P<0.05).The average hospitalisation duration was 6.54±2.48 days in the PMT group and 8.14±3.56 days in the CDT group.The incidence of PTS was lower in the PMT group than in the CDT group;however,the difference was not statistically significant(P<0.05).CONCLUSION Compared with CDT,treatment of LEDVT via PMT was associated with a better thrombus clearance rate,clinical therapeutic effect and PTS prevention function,but the difference was not statistically significant.Moreover,PMT was associated with a reduced urokinase dosage,shortened hospitalisation duration and reduced incidence of complications,such as infections and small haemorrhages.These results indicate that PMT has substantial beneficial effects in the treatment of LEDVT.

Analysis thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis in the lower extremities

Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein thrombosis (DVT) in the lower extremities treated by thrombolysis with anticoagulation and dispersion drugs were analyzed retrospectively. Results: The thrombolytic effect was significant. After treatment, the deep veins were recanalized without regurgitation in 75.3% of the patients. The total effective rate was 100%. Only three patients had hemorrhagic complication, but none of the patients died. Conclusion: Thrombolysis with anticoagulation treatment is an effective and safe method for DVT at the early stage.

Prevention and Treatment of Deep Vein Thrombosis of the Lower Limbs in Patients with Complications after Orthopedic Trauma Surgery

Objective:To explore and analyze on how to prevent and treat deep vein thrombosis of the lower limbs in patients with complications after orthopedic trauma surgery.Methods:The research patients were selected from the cases of surgical treatment of orthopedic trauma in the hospital during the past two years,and a total of 58 patients were selected.The patients were randomly divided into two groups,with 29 patients in the control group treated with conventional clinical methods;and the other 29 patients were assigned to the experimental group,where targeted preventive and therapeutic measures were administered.During the research,the number of complications of postoperative deep vein thrombosis of the lower limbs and the corresponding treatment efficacy were compared between the two groups of patients.Results:According to the results of clinical experiments,the probability of patients in the experimental group suffering from deep vein thrombosis of the lower limbs after surgery was significantly lower than that of the control group(P<0.05);in addition,when complications of deep venous thrombosis of the lower limbs occurred,the treatment efficacy of the patients in the experimental group was 96.55%,and the treatment efficacy of the patients in the control group was 82.76%.There was a significant difference between the two groups(P<0.05).Conclusion:Through clinical experiments to study and analyze the prevention and treatment measures of deep vein thrombosis in patients with complications after orthopedic trauma surgery,this research proves that active and comprehensive preventive and treatment measures can effectively reduce the number of complications and improve surgery treatment efficacy.

Establishment of a nomogram model for predicting therapy complications in patients with polycythemia and deep venous thrombosis

BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patient outcomes can be easily complicated by high-altitude polycythemia(HAPC),which increases the difficulty of treatment and the risk of recurrent thrombosis.To prevent reaching this point,effective screening and targeted interventions are crucial.Thus,this study analyzes and provides a reference for the clinical prediction of thrombosis recurrence in patients with lower-extremity DVT combined with HAPC.AIM To apply the nomogram model in the evaluation of complications in patients with HAPC and DVT who underwent anticoagulation therapy.METHODS A total of 123 patients with HAPC complicated by lower-extremity DVT were followed up for 6-12 months and divided into recurrence and non-recurrence groups according to whether they experienced recurrence of lower-extremity DVT.Clinical data and laboratory indices were compared between the groups to determine the influencing factors of thrombosis recurrence in patients with lowerextremity DVT and HAPC.This study aimed to establish and verify the value of a nomogram model for predicting the risk of thrombus recurrence.RESULTS Logistic regression analysis showed that age,immobilization during follow-up,medication compliance,compliance with wearing elastic stockings,and peripheral blood D-dimer and fibrin degradation product levels were indepen-dent risk factors for thrombosis recurrence in patients with HAPC complicated by DVT.A Hosmer-Lemeshow goodness-of-fit test demonstrated that the nomogram model established based on the results of multivariate logistic regression analysis was effective in predicting the risk of thrombosis recurrence in patients with lowerextremity DVT complicated by HAPC(χ^(2)=0.873;P>0.05).The consistency index of the model was 0.802(95%CI:0.799-0.997),indicating its good accuracy and discrimination.CONCLUSION The column chart model for the personalized prediction of thrombotic recurrence risk has good application value in predicting thrombotic recurrence in patients with lower-limb DVT combined with HAPC after discharge.

Comparison of four clinical scores for the predicting lower limb deep venous thrombosis in Chinese patients

Objective：To evaluate Wells, Kahn, St.Andr 6 and Constans scores for the prediction of deep venous thrombosis in Chinese patients. Methods：One hundred and seventy-two patients, prospectively, blinded referred for evaluation with four clinical-score systems for suspected deep venous thrombosis, were examined by ultrasonography. Sensitivity, specificity, positive predictive value, negative predictive value and receiver operation curves were calculated for four clinical scores. The difference between areas of the ROC curve for each of the scores was compared with others and reference line. Results：Forty-six of 172 patients had deep venous thrombosis proven by sonography. The sensitivity, specificity, positive predictive value and negative predictive value for Wells score was 91.3%, 57.1%, 43.8% and 94.7%, respectively, for Kahn score; 65.2%, 71.4%, 45.5% and 84.9%, respectively, for St.Andr 6 score; 63%, 38.9%, 27.4% and 74.2% respectively, for Constans score; 95.7%, 34.9%, 34.9% and 95.7% respectively. Area under ROV curve of Constans score was 0.814, which was similar to that of Wells score, then followed by Kahn score and that of St.Andr 6 score was no difference with the reference line. Conclusion：Based on the results of our study, the sensitivity, negative prediction value and area under ROC curve are larger for Constans score and Wells score in Chinese hospitalized patients than that of Kahn score or St.Andr 6 score. Considering the aim of the clinical assessment, Constans score and Wells score are more efficient for Chinese hospitalized patients.

Combined effect of Traditional Chinese Medicine decoction and low-molecular-weight heparin calcium on the postoperative deep venous thrombosis in patients with lower limb fracture

OBJECTIVE: To investigate the combined effect of Traditional Chinese Medicine(TCM) decoction and low-molecular-weight heparin calcium on deep vein thrombosis(DVT) induced by surgery in patients with lower limb fracture.METHODS: Totally 86 hospitalized patients with DVT after surgery of lower limb fracture between September 2012 and January 2015 were recruited and randomly divided into control group and observation group, 43 cases in each group. The patients in the control group were treated with subcutaneous injection of low-molecular-weight heparin calcium, and those in the observation group were additionally given Danshen Injection and TCM decoction. The differences between two groups in occurrence rate, medication time, therapeutic effects,recurrence rate of thrombosis, activated partial thromboplastin time(APTT), and prothrombin time(PT) were compared.RESULTS: The occurrence rate of DVT in observation group(4.65%, 2/43) was lower than that in control group(27.91%,12/43)(P<0.05). The medication time of observation group was(6.15±2.94) d, shorter than(9.76±3.12) d in the control group(P<0.05). In observation group, 2 cases of DVT were cured(2/2); in the control group, 9 cases presented therapeutic effects and the total effective rate was 75.00%(9/12). The improvement of APTT and PT in the observation group was better than that in the control group(P<0.05).CONCLUSION: Integrative TCM decoction plus low-molecularweight heparin calcium is superior to applicaton of low-molecularweight heparin calcium alone in reducing and treating DVT in the postoperative patients with lower limb fracture.

Clinical Application of Percutaneous Transluminal Angioplasty and Stent Implantation in Acute Lower Extremity Deep Venous Thrombosis

Purpose: To analyze the application of percutaneous transluminal angioplasty and stenting in acute deep venous thrombosis of lower extremities. Methods: 70 patients were divided into two groups according to the presence or absence of percutaneous transluminal angioplasty and stenting. Results: The mean circumferential diameter difference between the affected limbs and the healthy limbs and the knees at 15 cm was statistically significant. The cure rate and effective rate of the research group were higher than those of the control group (P<0.05). Conclusion: Percutaneous transluminal angioplasty and stenting are of high value in acute lower extremity deep venous thrombosis.

Discussion on Prevention and Treatment of Lower Extremity Deep Venous Thrombosis in Orthopedic Perioperative Period from Spleen and Stomach Meridians

Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.

Preventing Lower Extremity Deep Vein Thrombosis After Hip Fracture Surgery in Elderly Patients by Acupoint Application Combined with Pneumatic Compression Therapy

Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.

Two-point compression ultrasonography: Enough to rule out lower extremity deep venous thrombosis?

BACKGROUND: Deep venous thrombosis(DVT) is a major cause of morbidity and is a common presenting complaint to the emergency department(ED). Point-of-care two-point compression ultrasonography has evolved as a quick and effective way of diagnosing DVT. The purpose of this study is to validate the prevalence and distribution of venous thrombi isolated to proximal lower extremity veins, other than common femoral and popliteal veins in patients with DVT.METHODS: This is a single-center retrospective study that looked at patients presenting to the ED of a tertiary care hospital between January 2014 and August 2018. The clinical presentation and laboratory and imaging results were obtained using the hospital's electronic medical record.RESULTS: A total of 2,507 patients underwent a lower extremity duplex ultrasound during the study period. Among them, 379(15%) were included in the study. The percentages of isolated thrombi to the femoral vein and deep femoral vein were 7.92% and 0.53%, respectively. When the patients were stratified into the two groups of isolated DVT and two-point compression DVT, there were no statistically significant differences in the laboratory results between both groups. However, immobilized patients and patients with recent surgeries were more likely to have an isolated DVT.CONCLUSIONS: Thrombi isolated to proximal lower extremity veins other than the common femoral and popliteal veins make up 8.45% of DVTs. Given this significant number of missed DVTs, the authors recommend the addition of the femoral and deep femoral veins to the two-point compression exam.

Upper extremity deep vein thrombosis:An intensivist’s perspective

Upper extremity deep vein thrombosis(UEDVT)is less common than lower extremity DVT but is a cause of significant morbidity and mortality in intensive care unit patients.Increasing cancer incidence,prolonged life expectancy and increasing use of intravascular catheters and devices has led to an increased incidence of UEDVT.It is also associated with high rates of complications like pulmonary embolism,post-thrombotic syndrome and recurrent thrombosis.Clinical prediction scores and D-dimer may not be as useful in identifying UEDVT;hence,a high suspicion index is required for diagnosis.Doppler ultrasound is commonly employed for diagnosis,but other tests like computed tomography and magnetic resonance imaging venography may also be required in some patients.Contrast venography is rarely used in patients with clinical and ultrasound findings discrepancies.Anticoagulant therapy alone is sufficient in most patients,and thrombolysis and surgical decompression is seldom indicated.The outcome depends on the cause and underlying comorbidities.

大隐静脉曲张患者术后DVT发生率及危险因素分析

目的:关于大隐静脉曲张患者术后下肢深静脉血栓(DVT)发生率及危险因素分析。方法:选取2019年8月—2023年8月样本医院收治的97例大隐静脉曲张患者作为研究对象,所有患者均接受大隐静脉高位结扎+静脉曲张剥脱术进行手术治疗,根据患者术后是否出现DVT将其分为研究组(n=14)和对照组(n=83)。统计患者术后出现DVT的发生率,收集患者的一般资料并进行logistic回归分析,探寻影响患者出现DVT的危险因素。结果:术后97例患者中发生DVT的共14例,发生率为14.43%;单因素分析结果显示,年龄≥60岁、合并糖尿病、术前1个月使用过激素类药物、静脉曲张病程≥5年、D-二聚体(D-Dminer)水平比较,差异均有统计学意义(χ^(2)=6.634、4.318、6.251、4.430;t=11.545,P<0.05);logistic回归分析结果显示,年龄≥60岁、合并糖尿病、术前1个月使用过激素类药物、静脉曲张病程≥5年、D-Dimer水平是大隐静脉患者术后发生DVT的危险因素(OR=2.303、3.618、2.347、2.435、2.866,P<0.05)。结论:大隐静脉患者术后DVT发生率为14.43%,年龄、合并糖尿病、术前1个月使用过激素类药物≥5年、静脉曲张病程、D-Dimer水平是导致患者术后发生DVT的危险因素。

基于临床路径的分级护理在骨科患者术后下肢深静脉血栓预防中的应用效果

目的:探讨基于临床路径的分级护理在骨科患者术后下肢深静脉血栓(DVT)预防中的应用效果。方法:选取2023年4月—2024年8月于徐州市第一人民医院骨科接受手术治疗的84例患者为研究对象,采用随机数字表法分为常规组(n=42)与观察组(n=42)。常规组实施常规护理,观察组实施基于临床路径的分级护理。比较两组护理效果。结果:护理后,两组纤维蛋白原、D-二聚体水平均降低,且观察组低于常规组(P<0.05)。两组护理前后凝血时间、凝血酶原时间、活化部分凝血活酶时间比较,无统计学差异(P>0.05)。护理后,两组生活质量评分均高于护理前,且观察组高于常规组(P<0.05)。观察组下肢并发症总发生率低于常规组(P=0.026)。结论:基于临床路径的分级护理在骨科患者术后DVT预防中的应用效果较好,能够改善患者的凝血功能,降低下肢并发症发生率,提高生活质量。

利伐沙班与华法林治疗老年下肢深静脉血栓的效果比较

目的:本研究旨在比较利伐沙班和华法林在老年下肢深静脉血栓(DVT)治疗中的效果和安全性。方法:本研究为前瞻性随机对照试验,选取启东市人民医院2021年6月—2023年12月收治的102例老年下肢DVT患者,随机分为对照组(华法林组)和观察组(利伐沙班组),各51例。比较两组患者的下肢静脉栓子检出率,以及用药前、用药5 d和10 d后的血液流变学指标(全血高切黏度、全血低切黏度、血浆黏度及红细胞聚集指数)和凝血功能指标[凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、D-二聚体(D-D)]。结果:用药10 d,观察组下肢静脉栓子检出率显著低于对照组(P<0.05)。在血液流变学指标方面,用药5 d和10 d后,观察组全血高切黏度、全血低切黏度、血浆黏度、红细胞聚集指数均低于对照组(P<0.05)。对于凝血功能指标,用药5 d和10 d后,观察组的TT、PT和APTT均长于对照组(P<0.05),FIB水平和D-D水平均低于对照组(P<0.05)。结论:在治疗老年下肢DVT方面,利伐沙班相较于华法林表现出更低的静脉栓子检出率和更好的血液流变学及凝血功能改善效果。因此,利伐沙班可作为一种更有效的治疗选择。

炎症因子及凝血指标在下肢深静脉血栓形成中的检测价值

目的:分析炎症因子及凝血指标在下肢深静脉血栓形成中的检测价值。方法:选择2020年2月—2023年4月苏州市相城人民医院收治的65例下肢深静脉血栓患者作为观察组,另选择同期于本院体检的65例健康志愿者作为对照组;按照病程将观察组分成甲组(病程≤30 d)、乙组(病程>30 d)。比较各组的炎症因子[C反应蛋白(CRP)、白细胞介素-6(IL6)、γ干扰素(IFN-γ)]、凝血指标[D-二聚体(D-D)、凝血因子Ⅷ(FⅧ)、凝血因子Ⅳ(FⅣ)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)]。结果:观察组CRP、IL-6、IFN-γ、D-D水平均高于对照组,TT长于对照组,PT、APTT均短于对照组,差异均有统计学意义(P<0.05)。甲组CRP、IL-6、IFN-γ、D-D水平均高于乙组,TT长于乙组,PT、APTT均短于乙组,差异均有统计学意义(P<0.05)。结论:检测炎症因子、凝血指标水平有助于了解下肢深静脉血栓患者与健康人之间的区别,判断下肢深静脉血栓形成病程,为下肢深静脉血栓的早期诊断、疾病监测提供参考数据。

集束化护理对预防缺血性脑卒中后下肢深静脉血栓形成的效果

目的探讨集束化护理干预对于减少缺血性脑卒中患者并发下肢深静脉血栓的疗效。方法选取自2023年1月至2023年12月,在本院接受治疗的60例缺血性脑卒中患者作为样本,所有患者在入院后均接受标准溶栓治疗。通过随机数字表法将这些患者分为常规护理的对照组和集束化护理的观察组,每组各30例。对照组采用传统的护理措施,观察组采用集束化护理干预。对比两组患者下肢深静脉血栓的发生率,并对两组的凝血功能指标及下肢深静脉血栓健康信念量表评分进行对比分析。结果观察组的下肢深静脉血栓发生率较对照组低(P<0.05);在下肢深静脉血栓健康信念量表的各个维度评分中,观察组均高于对照组(P<0.05);在凝血功能指标方面,护理后观察组的凝血酶原时间(PT)、凝血酶时间(TT)和凝血活酶时间(APTT)均高于对照组,而纤维蛋白原(Fbg)水平低于对照组(P<0.05)。结论针对缺血性脑卒中患者开展集束化护理工作,可以强化其下肢深静脉血栓形成的健康信念,降低下肢深静脉血栓形成发生率。

多学科联合五阶梯渐进式活动方案在ICU机械通气病人中的应用

目的:探究多学科联合五阶梯渐进式活动方案在重症监护病房(ICU)机械通气病人中的应用效果。方法:选取2022年5月—2023年7月就诊于青岛市某医院的ICU机械通气病人为研究对象,根据入院时间将病人分为对照组(49例)和干预组(48例)。对照组采用重症常规治疗与护理方法进行干预,干预组采用多学科联合五阶梯渐进式活动方案进行干预。比较两组病人ICU获得性衰弱(ICU-AW)发生率、日常生活活动能力、ICU获得性谵妄发生率、机械通气时长、ICU住院时间、下肢深静脉血栓发生率。结果:干预组病人Barthel指数为(29.48±14.26)分,高于对照组[(17.14±14.25)分];机械通气时间为(5.56±3.75)d,ICU住院时间为(8.15±3.94)d,短于对照组[机械通气时间为(7.92±6.28)d,ICU住院时间为(11.69±8.73)d];ICU-AW发生率为17%,ICU获得性谵妄发生率为2%,下肢深静脉血栓发生率为21%,低于对照组[ICU-AW发生率为37%,ICU获得性谵妄发生率为27%,下肢深静脉血栓发生率为49%],差异均有统计学意义(均P<0.05)。结论:实施多学科联合五阶梯渐进式活动方案有利于提高ICU机械通气病人日常生活活动能力,降低ICU-AW、ICU获得性谵妄和下肢深静脉血栓发生率,缩短机械通气时间及ICU住院时间。