全耳内镜下耳屏软骨-软骨膜复合体在上鼓室外侧壁重建中的临床应用

目的探究全耳内镜下耳屏软骨-软骨膜复合体在上鼓室外侧壁重建中的临床应用。方法选取2020年6月~2023年6月间徐州市中心医院收治的58例进行上鼓室外侧壁重建的胆脂瘤患者,根据采用修复材料的不同分为对照组及观察组各29例。对照组采用耳屏软骨膜进行上鼓室外侧壁重建,观察组采用耳屏软骨-软骨膜复合体进行上鼓室外侧壁重建,两组患者均于全耳内镜下进行手术。统计患者术中出血量、手术时间,术后3个月复查听力情况、干耳情况及耳道功能改善情况,术后随访6个月鼓膜愈合情况。结果与术前比较,术后3个月气导听阈、气骨导差降低(P<0.05),与对照组比较,观察组气导听阈、气骨导差降低(P<0.05);与对照组比较,观察组干耳率、耳道功能良好率、听力提高成功率均升高,干耳时间缩短,但耳屏愈合时间增加(P<0.05);与对照组比较,观察组手术时间缩短,术中出血量减少(P<0.05);观察组、对照组术后并发症总发生率分别为13.79%、24.14%,二者比较差异无统计学意义(P>0.05);观察组愈合良好率高于对照组(86.21%vs.62.07%)(P<0.05),两组患者耳膜穿孔(10.34%vs.24.14%)、鼓膜移位(3.45%vs.6.90%)及鼓膜回缩(0.00%vs.6.90%)发生情况比较,差异无统计学意义(P>0.05)。结论全耳内镜下耳屏软骨-软骨膜复合体在上鼓室外侧壁重建中有利于改善患者听力,有利于术后恢复。

Disassembly of the fruit cell wall by the ripening-associated polygalacturonase and expansin influences tomato cracking

Fruit cracking is an important problem in horticultural crop production.Polygalacturonase(SlPG)and expansin(SlEXP1)proteins cooperatively disassemble the polysaccharide network of tomato fruit cell walls during ripening and thereby,enable softening.A Golden 2-like(GLK2)transcription factor,SlGLK2 regulates unripe fruit chloroplast development and results in elevated soluble solids and carotenoids in ripe fruit.To determine whether SlPG,SlEXP1,or SlGLK2 influence the rate of tomato fruit cracking,the incidence of fruit epidermal cracking was compared between wild-type,Ailsa Craig(WT)and fruit with suppressed SlPG and SlEXP1 expression(pg/exp)or expressing a truncated nonfunctional Slglk2(glk2).Treating plants with exogenous ABA increases xylemic flow into fruit.Our results showed that ABA treatment of tomato plants greatly increased cracking of fruit from WT and glk2 mutant,but not from pg/exp genotypes.The pg/exp fruit were firmer,had higher total soluble solids,denser cell walls and thicker cuticles than fruit of the other genotypes.Fruit from the ABA treated pg/exp fruit had cell walls with less water-soluble and more ionically and covalently-bound pectins than fruit from the other lines,demonstrating that ripening-related disassembly of the fruit cell wall,but not elimination of SlGLK2,influences cracking.Cracking incidence was significantly correlated with cell wall and wax thickness,and the content of cell wall protopectin and cellulose,but not with Ca^(2+)content.

Cracking Patterns of Shear Walls in Reinforced Concrete Structure due to Strong Earthquake Based on Mohr-Coulomb Criterion

A primary goal of seismic design of buildings is to protect people's life safety during strong earthquakes. Fundamentally,to predict the survived space and estimate people escape intervals during structural collapse are very important,which requires to describe the failure process more detailedly not only for structural joints but also for slabs and shear walls. In the present paper,the details of Mohr-Coulomb failure criterion with tension-cutoff together with its expression in failure surface and local coordinate system of reinforced concrete( RC) shear wall are given firstly,and then several typical cracking patterns of RC shear wall,such as tension shear crack and compression shear crack, are analyzed based on Mohr-Coulomb failure criterion with tension-cutoff.

SlGH9-15 regulates tomato fruit cracking with hormonal and abiotic stress responsiveness cis-elements

Fruit cracking occurs easily during the late period of fruit development when plants encounter an unsuitable environment,dramatically affecting fruit production and marketing.This study conducted the bulked segregant RNA-Seq(BSR)to identify the key regulatory gene of fruit cracking in tomatoes.BSR-Seq analysis illustrated that two regions associated with irregularly cracking were located on chromosomes 9 and 11,containing 127 candidate genes.Further,through differentially expression analysis and qRT-PCR in cracking-susceptible and cracking-resistant genotypes,the candidate gene SlGH9-15(Solyc09g010210)with significantly differential expression levels was screened.Bioinformatics analysis of the GH9 gene family revealed that 20 SlGH9 genes were divided into three groups.The phylogenetic analysis showed that SlGH9-15 was closely related to cell wall construction-associated genes AtGH9B1,AtGH9B6,OsGH9B1,and OsGH9B3.The cis-acting elements analysis revealed that Sl GH9-15 was activated by various hormones(ethylene and ABA)and abiotic stresses.The expression pattern indicated that 13 SlGH9 genes,especially SlGH9-15,were highly expressed in the cracking-susceptible genotype.Its expression level gradually increased during fruit development and achieved maximum value at the red ripe stage.Additionally,the cracking-susceptible tomato showed higher cellulase activity and lower cellulose content than the cracking-resistant tomato,particularly at the red ripe stage.This study identified SlGH9-15 as a key gene associated with fruit cracking in tomatoes for the first time and gives new insights for understanding the molecular mechanism and complex regulatory network of fruit cracking.

Wall Cracks Detection in Aerial Images Using Improved Mask R-CNN

The present paper proposes a detection method for building exterior wall cracks since manual detection methods have high risk and low efficiency.The proposed method is based on Unmanned Aerial Vehicle(UAV)and computer vision technology.First,a crack dataset of 1920 images was established using UAV to collect the images of a residential building exterior wall under different lighting conditions.Second,the average crack detection precisions of different methods including the Single Shot MultiBox Detector,You Only Look Once v3,You Only Look Once v4,Faster Regional Convolutional Neural Network(R-CNN)and Mask R-CNN methods were compared.Then,the Mask R-CNN method with the best performance and average precision of 0.34 was selected.Finally,based on the characteristics of cracks,the utilization ratio of Mask R-CNN to the underlying features was improved so that the average precision of 0.9 was achieved.It was found that the positioning accuracy and mask coverage rate of the proposed Mask R-CNN method are greatly improved.Also,it will be shown that using UAV is safer than manual detection because manual parameter setting is not required.In addition,the proposed detection method is expected to greatly reduce the cost and risk of manual detection of building exterior wall cracks and realize the efficient identification and accurate labeling of building exterior wall cracks.

基于航拍图像与改进U-Net的建筑外墙裂缝检测方法

针对建筑外墙裂缝人工检测方法检测效率低、检测效果和安全性差的问题,提出基于航拍图像与计算机视觉的裂缝检测方法。使用无人机绕建筑物航拍采集裂缝图像,并构建裂缝数据集;优化U-Net模型以解决细长裂缝分割不连续、复杂背景下裂缝漏检及背景误检的问题。将模型编码网络替换为预训练的ResNet50以提升模型特征表达能力;添加改进的多孔空间金字塔池化(Atrous Spatial Pyramid Pooling,ASPP)模块,获取多尺度上下文信息;采用改进的损失函数处理裂缝图像正负样本分布极度不均的问题。结果表明:改进的U-Net模型解决了原模型存在的问题,IoU指标和F1_score分别提升了3.53%、4.18%;与经典分割模型相比,改进模型的裂缝分割性能最优。与人工检测方法相比,所提方法可以安全、高效且准确地进行建筑外墙裂缝检测。

钢板-混凝土组合剪力墙裂缝控制及监测分析

以实际工程为背景,对1.7 m厚钢板-混凝土组合剪力墙的裂缝控制及监测进行分析。大体积混凝土构件,由于其水化热比较高容易产生温度裂缝,基于此首先对原材料及配合比进行优化设计,降低混凝土水化热。然后对大厚度组合剪力墙浇筑后采取合理的养护措施控制其内部温度以及对裂缝发生情况进行实测分析,最后经过一系列针对性的裂缝控制措施及监测结果表明,采用优化设计对大厚度组合剪力墙的裂缝控制优于同类工程的裂缝控制效果。

2198-T8铝锂合金多轴疲劳性能及裂纹扩展行为

对2198-T8铝锂合金薄壁管状试样在不同加载条件下进行了拉扭复合疲劳裂纹扩展试验。结果明,随着裂纹扩展阶段的等效应力幅降低,试样的多轴疲劳寿命升高。当应力幅比升高时,多轴疲劳寿命降低,轴向应变变大,扭向应变变小,扭向应变集中滞后于轴向应变集中。结合数字图像相关技术,拟合疲劳裂纹扩展速率模型,并采用两种临界平面模型对裂纹扩展方向进行预测,其中最大正应力平面对裂纹扩展方向的预测效果最好。随着应力幅比的升高,裂纹扩展区微观形貌由磨损形貌变为磨损与疲劳条带共存的形貌,裂纹扩展模式由II型变为I+II型,最终变为以I型为主。

Numerical analysis of confinement effect on crack propagation mechanism from a flaw in a pre-cracked rock under compression

In many situations rocks are subjected to biaxial loading and the failure process is controlled by the lateral confinement stresses. The importance of confinement stresses has been recognized in the literature by many researchers, in particular, its influence on strength and on the angle of fracture, but still there is not a clear description for the influence of confining stress on the crack propagation mechanism of rocks. This paper presents a numerical pro- cedure for the analysis of crack propagation in rock-like ma- terials under compressive biaxial loads. Several numerical simulations of biaxial tests on the rock specimen have been carried out by a bonded particle model （BPM） and the influ- ence of confinement on the mechanism of crack propagation from a single flaw in rock specimens is studied. For this purpose, several biaxial compressive tests on rectangular spec- imens under different confinement stresses were modeled in （2 dimensional particle flow code） PFC2D. The results show that wing cracks initiate perpendicular to the flaw and trend toward the direction of major stress, however, when the lat- eral stresses increase, this initiation angle gets wider. Also it is concluded that in addition to the material type, the initiation direction of the secondary cracks depends on confine- ment stresses, too. Besides, it is understood that secondary cracks may be produced from both tensile and shear mechanisms.

Flow behavior in microchannel made of different materials with wall slip velocity and electro-viscous effects

In a microfluidic system, flow slip velocity on a solid wall can be the same order of magnitude as the average velocity in a microchannel. The flow-electricity interaction in a complex microfluidic system subjected to joint action of wall slip and electro-viscous effect is an important topic. This paper presents an analytic solution of pressuredriven liquid flow velocity and flow-induced electric field in a two-dimensional microchannel made of different materials with wall slip and electro-viscous effects. The Poisson- Boltzmann equation and the Navier-Stokes equation are solved for the analytic solutions. The analytic solutions agree well with the numerical solutions. It was found that the wall slip amplifies the fow-induced electric field and enhances the electro-viscous effect on flow. Thus the electro-viscous effect can be significant in a relatively wide microchannel with relatively large kh, the ratio of channel width to thickness of electric double layer, in comparison with the channel without wall slip.

Development of X-FEM methodology and study on mixed-mode crack propagation

The extended finite element method（X-FEM） is a novel numerical methodology with a great potential for using in multi-scale computation and multi-phase coupling problems. The algorithm is discussed and a program is developed based on X-FEM for simulating mixed-mode crack propagation. The maximum circumferential stress criterion and interaction integral are deduced. Some numerical results are compared with the experimental data to prove the capability and efficiency of the algorithm and the program. Numerical analyses of sub-interfacial crack growth in bi-materials give a clear description of the effiect on fracture made by interface and loading condition.

A continuous-discontinuous cellular automaton method for cracks growth and coalescence in brittle material

A method of continuous-discontinuous cellular automaton for modeling the growth and coalescence of multiple cracks in brittle material is presented. The method uses the level set to track arbitrary discontinuities, and calculation grids are independent of the discontinuities and no remeshing are required with the crack growing. Based on Grif- fith fracture theory and Mohr-Coulumb criterion, a mixed fracture criterion for multiple cracks growth in brittle mate- rial is proposed. The method treats the junction and coales- cence of multiple cracks, and junction criterion and coales- cence criterion for brittle material are given, too. Besides, in order to overcome the tracking error in the level set ap- proximation for crack junction and coalescence, a dichotomy searching algorithm is proposed. Introduced the above the- ories into continuous-discontinuous cellular automaton, the present method can be applied to solving multiple crack growth in brittle material, and only cell stiffness is needed and no assembled global stiffness is needed. Some numerical examples are given to shown that the present method is efficient and accurate for crack junction, coalescence and percolation problems.

NUMERICAL SIMULATION OF STRESS-STRAIN DISTRIBUTIONS FOR WELD METAL SOLIDIFICATION CRACKING IN STAINLESS STEEL

This paper analyzed the characteristics of welding solidification crack of stainless steels,and clearly re- vealed the the of the deformation in the molten - the pool and the solidification shrinkage on the stress - strain fields in the trail of molten - weld pool.Moreover, rheologic properties of the alloys in solid - liquid zone were also obtained by measuring the hading and unloading deform curves of the steels.As a result, a numerical model for simulation of stress - strain distributions of welding solidifi- cation crack was developed. On the basis of the model,the thesis simulated the driving force of solidifi- cation crack of stainless steels, that is, stress - strain fields in the trail of molten-weld pool with fi- nite element method.

Determination of <i>α</i>-1,3-Linked Mannose Residue in the Cell Wall Mannan of <i>Candida tropicalis</i>NBRC 1400 Strain

To investigate the chemical structure of cell wall mannan obtained from pathogenic yeast, Candida tropicalis NBRC 1400 (former antigenic standard strain, IFO 1400). As a result of two-dimensional NMR analysis, it was shown that the mannan of this strain is composed of α-1,6-, α-1,3-, α-1,2- and β-1,2-linked mannose residues. In this research, the mannan was subjected to three degradation procedures, acid-treatment, α-mannosidase, and acetolysis under two conditions in order to determine the chemical structure of the antigenic oligomannosyl side chains in this molecule. The 1H-nuclear magnetic resonance spectra of resultant oligosaccharides, pentaose and hexaose, demonstrated the existence of the oligomannosyl side chains corresponding to Manα1-3Manα1-2Manα1-2Manα1-2Man and Manα1-3Manα1-2Manα1-2Manα1-2Manα1-2Man, respectively, which have previously also been found in Candida albicans serotype A strain mannans. These findings indicate that C. tropicalis and C. albicans serotype A have no significant difference in the chemical structure of these cell wall mannans. Therefore, it can be interpreted that it is extremely difficult to distinguish both species by targeting the antigenic group in these mannans.

Investigation on Cracking of Concrete Shear Wall under Exceeded Temperature Differences Rate

In situ, the changes of temperature, deformation, and stressing of steel bar of C40 reinforced concrete shear wall were measured, respectively. The results are obvious that the temperature change of climate is one of the most effective factors which could lead the concrete shear wall to cracking at earlier age. The temperature differences between inside and outside concrete shear wall are so large that the concrete will gain larger shrinkage. This larger shrinkage which is caused by the temperature reducing ratio will gain the strained action of head, end and reinforced steel bar of concrete shear wall. This action can lead to tensile stress on the surface and inside concrete shear wall. If the tensile stress would exceed the pull strength of concrete, the concrete shear wall would crack and cause deterioration. Thus, the enhancing curing of concrete shear wall in suit at earlier age, and controlling temperature reducing ratio and deform caused by shrinkage, will be available treatments which control occurring and developing of cracking on concrete shear wall.

EXPERIMENTAL STUDY OF TENSILE CAPACITY OF CONCRETE IN RC SHEAR WALLS AFTER CRACKING

Through the test of 8 RC shear wall specimens and computer analysis ofstrains of steel bars with keyways in the specimens,the authors have studied the remains oftensile stress of concrete between cracks after concrete cracking and put forward a formulato calculate coefficient Ψ,the ununiform distribution factor of steel strain.This coefficientcan be used to modify the calculated steel strain in cracked zone,so as to make the resultsof using finite clement method to analyze shear walls more accurate.

Torsional Behavior Design of UHPC Box Beams Based on Thin-Walled Tube Theory

This study proposed a prediction formula for the torsional strength enabling to reflect the tensile strength of ultra high performance concrete (UHPC) beams based upon the thin-walled tube theory. The remarkable ductile behavior of UHPC can also be attributed to the steel fiber reinforcement. This feature must be considered to provide rational explanation of the torsional behavior of UHPC structures. In this study, the proposed torsional design adopts a modified thin-walled tube theory so as to consider the tensile behavior of UHPC. And torsion test was conducted on thin-walled UHPC box beams to validate the proposed formula through comparison of the predicted torsional strength with the experimental results. The comparison of the predicted values of the cracking torque and torsional moment resistance with those observed in the torsional test of UHPC verified the validity of the design method. The contribution of the steel fibers to the torsional strength and cracking load was larger than that of the stirrups, but the stirrups appeared to contribute additionally to the torsional ductility. Accordingly, it is recommended that design should exploit effectively the contribution of the steel fiber rather than arrange a larger number of stirrups in UHPC structures subjected to torsion.

Analysis of dynamic stress intensity factors of thick-walled cylinder under internal impulsive pressure

Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is used as the reference case, and then the weight function for a thick-walled cylinder containing a radial edge crack can be worked out. Secondly, the dynamic stresses in uncracked thick-walled cylinders are solved under internal impulsive pressure by using mode shape function method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary condi- tions, and the history and distribution of dynamic stresses in thick-walled cylinders are derived in terms of Fourier-Bessel series. Finally, the dynamic stress intensity factor equations for thick-walled cylinder containing a radial edge crack sub- jected to internal impulsive pressure are given by dynamic weight function method. The finite element method is utilized to verify the results of numerical examples, showing the validity and feasibility of the proposed method.

Controlling Methods and Causes of Wall Cracks of Civil and Industrial Construction Projects

Since the reform and opening up,Chinese economy has developed rapidly.Industrial and civil construction projects have made significant progress.That said,it is of great significance to further strengthen the construction management of industrial and civil construction projects for the longterm development of construction industry in China.In terms of reality,one of the common problems in the current industrial and civil construction is wall cracks,which will have an important impact on the appearance of the building and the overall construction quality.Therefore,it is necessary to analyze the reasons and put forward corresponding measures on it.That is how we can continuously improve the construction quality in civil and industrial construction projects,thereby achieving the enhancement of building safety and stability.

Penny-shaped interfacial crack between dissimilar magnetoelectroelastic layers

A penny-shaped interfacial crack between dissimilar magnetoelectroelastic layers subjected to magnetoelectromechanical loads is investigated,where the magnetoelectrically impermeable crack surface condition is adopted. By using Hankel transform technique,the mixed boundary value problem is firstly reduced to a system of singular integral equations,which are further reduced to a system of algebraic equations. The field intensity factors and energy release rate are finally derived. Numerical results elucidate the eects of crack configuration,electric and/or magnetic loads,and material parameters of the magnetoelectroelastic layers on crack propagation and growth. This work should be useful for the design of magnetoelectroelastic composite structures.