This paper studies a time-variant multi-objective linear fractional transportation problem. In reality, transported goods should reach in destinations within a specific time. Considering the importance of time, a time...This paper studies a time-variant multi-objective linear fractional transportation problem. In reality, transported goods should reach in destinations within a specific time. Considering the importance of time, a time-variant multi-objective linear fractional transportation problem is formulated here. We take into account the parameters as cost, supply and demand are interval valued that involved in the proposed model, so we treat the model as a multi-objective linear fractional interval transportation problem. To solve the formulated model, we first convert it into a deterministic form using a new transformation technique and then apply fuzzy programming to solve it. The applicability of our proposed method is shown by considering two numerical examples. At last, conclusions and future research directions regarding our study is included.展开更多
There exist three problems in the calculation of lateral vibration of the train-track time-variant system athome and abroad and the method to solve them is presented. Spatially coupling vibration analysis model of tra...There exist three problems in the calculation of lateral vibration of the train-track time-variant system athome and abroad and the method to solve them is presented. Spatially coupling vibration analysis model of train-track time-variant system is put forward. Each vehicle is modeled as a multi-body system with 26 degrees of freedomand the action of coupler is also considered. The track structure is modeled as an assembly of track elements with 30degrees of freedom, then the spatially coupling vibration matrix equation of the train-track time-variant system is es-tablished on the basis of the principle of total potential energy with stationary value and the "set-in-right-position"rule. The track vertical geometric irregularity is considered as the excitation source of the vertical vibration of thesystem, and the hunting wave of car bogie frame is taken as the excitation source of lateral vibration of the system.The spatially coupling vibration matrix equation of the system is solved by Wilson-θ direct integration method. Theapproximation of the calculated results to the spot test results demonstrates the feasibility and effectiveness of thepresented analysis method. Finally, some other vibration responses of the system are also obtained.展开更多
FPSO is a kind of important exploitation platform used in ocean oil and gas industry, which has the unique character of mooring at outsea for a long time. Since it can not be inspected and maintained thoronghly at doc...FPSO is a kind of important exploitation platform used in ocean oil and gas industry, which has the unique character of mooring at outsea for a long time. Since it can not be inspected and maintained thoronghly at dock like other kinds of ships, the reliability of FPSO hull girder during the whole service should be focused. Based on latest corrosion database and rational corrosion model, the ultimate strength of one FPSO is calculated under the conditions of slight, moderate and severe corrosion. The results not only provide the reliabihty under different corrosion conditions, but also do well for further inspection and maintenance research. The results provide necessary foundation for deciding inspection intervals and maintenance measure, which has practical sense to improve the general safety level of ocean engineering.展开更多
Survivin variants specific real time quantitative RT-PCR was developed to analyze their expression in 53 paired cancer and para-cancerous tissues, and the expression of the wild-type survivin protein was detected by i...Survivin variants specific real time quantitative RT-PCR was developed to analyze their expression in 53 paired cancer and para-cancerous tissues, and the expression of the wild-type survivin protein was detected by immunohistochemistry. The results showed that survivin mRNA and protein were expressed in gastric cancer and para-cancerous tissues, The survivin-2B was dominantly expressed in para-cancerous tissues, whereas the survivin-△Ex3 was more frequently detected in cancer tissues. The positive rate of survivin-2a was 100% in both cancer and para-cancerous tissues, but its relative transcript expression level was not significantly increased in cancer tissues in comparison with para-cancerous tissues. The correlation analysis revealed that the expression of survivin-2a mRNA was significantly associated with that of total survivin （rs=0.4178, P=0.0018）, whereas inversely to that of survivin-△EX3 （rs=-0.4506, P=0.0007）. It was suggested that survivin-2a may act as an antagonist of survivin-△EX3. The balance between antiapoptotic survivin iso-forms and nonantiapoptotic ones may play an important role in tumorigenesis and tumor progression, Promising value is hinted to analyze survivin and its variants in tumor early diagnosis and distinguishing malignant tumors from benign ones.展开更多
文摘This paper studies a time-variant multi-objective linear fractional transportation problem. In reality, transported goods should reach in destinations within a specific time. Considering the importance of time, a time-variant multi-objective linear fractional transportation problem is formulated here. We take into account the parameters as cost, supply and demand are interval valued that involved in the proposed model, so we treat the model as a multi-objective linear fractional interval transportation problem. To solve the formulated model, we first convert it into a deterministic form using a new transformation technique and then apply fuzzy programming to solve it. The applicability of our proposed method is shown by considering two numerical examples. At last, conclusions and future research directions regarding our study is included.
基金Project (50078006) supported by the National Natural Science Foundation of China Project (2001G029) supported by the Foundation of the Science and Technology Section of the Railway Bureau
文摘There exist three problems in the calculation of lateral vibration of the train-track time-variant system athome and abroad and the method to solve them is presented. Spatially coupling vibration analysis model of train-track time-variant system is put forward. Each vehicle is modeled as a multi-body system with 26 degrees of freedomand the action of coupler is also considered. The track structure is modeled as an assembly of track elements with 30degrees of freedom, then the spatially coupling vibration matrix equation of the train-track time-variant system is es-tablished on the basis of the principle of total potential energy with stationary value and the "set-in-right-position"rule. The track vertical geometric irregularity is considered as the excitation source of the vertical vibration of thesystem, and the hunting wave of car bogie frame is taken as the excitation source of lateral vibration of the system.The spatially coupling vibration matrix equation of the system is solved by Wilson-θ direct integration method. Theapproximation of the calculated results to the spot test results demonstrates the feasibility and effectiveness of thepresented analysis method. Finally, some other vibration responses of the system are also obtained.
基金This research was financially supported by the National Natural Science Foundation of China (Grant No50323004)
文摘FPSO is a kind of important exploitation platform used in ocean oil and gas industry, which has the unique character of mooring at outsea for a long time. Since it can not be inspected and maintained thoronghly at dock like other kinds of ships, the reliability of FPSO hull girder during the whole service should be focused. Based on latest corrosion database and rational corrosion model, the ultimate strength of one FPSO is calculated under the conditions of slight, moderate and severe corrosion. The results not only provide the reliabihty under different corrosion conditions, but also do well for further inspection and maintenance research. The results provide necessary foundation for deciding inspection intervals and maintenance measure, which has practical sense to improve the general safety level of ocean engineering.
文摘Survivin variants specific real time quantitative RT-PCR was developed to analyze their expression in 53 paired cancer and para-cancerous tissues, and the expression of the wild-type survivin protein was detected by immunohistochemistry. The results showed that survivin mRNA and protein were expressed in gastric cancer and para-cancerous tissues, The survivin-2B was dominantly expressed in para-cancerous tissues, whereas the survivin-△Ex3 was more frequently detected in cancer tissues. The positive rate of survivin-2a was 100% in both cancer and para-cancerous tissues, but its relative transcript expression level was not significantly increased in cancer tissues in comparison with para-cancerous tissues. The correlation analysis revealed that the expression of survivin-2a mRNA was significantly associated with that of total survivin （rs=0.4178, P=0.0018）, whereas inversely to that of survivin-△EX3 （rs=-0.4506, P=0.0007）. It was suggested that survivin-2a may act as an antagonist of survivin-△EX3. The balance between antiapoptotic survivin iso-forms and nonantiapoptotic ones may play an important role in tumorigenesis and tumor progression, Promising value is hinted to analyze survivin and its variants in tumor early diagnosis and distinguishing malignant tumors from benign ones.
