Parameter calibration of the tensile-shear interactive damage constitutive model for sandstone failure

The tensile-shear interactive damage(TSID)model is a novel and powerful constitutive model for rock-like materials.This study proposes a methodology to calibrate the TSID model parameters to simulate sandstone.The basic parameters of sandstone are determined through a series of static and dynamic tests,including uniaxial compression,Brazilian disc,triaxial compression under varying confining pressures,hydrostatic compression,and dynamic compression and tensile tests with a split Hopkinson pressure bar.Based on the sandstone test results from this study and previous research,a step-by-step procedure for parameter calibration is outlined,which accounts for the categories of the strength surface,equation of state(EOS),strain rate effect,and damage.The calibrated parameters are verified through numerical tests that correspond to the experimental loading conditions.Consistency between numerical results and experimental data indicates the precision and reliability of the calibrated parameters.The methodology presented in this study is scientifically sound,straightforward,and essential for improving the TSID model.Furthermore,it has the potential to contribute to other rock constitutive models,particularly new user-defined models.

Time-varying impact of political risk on copper prices

Using the International Country Risk Guide(ICRG)index to represent countries’political risk,the time-varying effect of political risk on copper prices was examined based on the time-varying parameter structural vector autoregression with stochastic volatility(TVP-SVAR-SV)model.The empirical results show that the impact of political risk on copper prices is time-varying and has tended to increase gradually in recent years.There are significant country-level differences in the impact of political risk on copper prices.Political risk has a stronger and longer-lasting impact on copper prices in exporting countries.In terms of risk sources,external and internal conflicts contribute most to international copper price fluctuations in the sample period.The impact of political risk on copper prices reaches an extreme level during the international financial crisis,the European debt crisis,and the election of Donald Trump.

A Possible Mechanism of the Impact of Atmosphere-Ocean Interaction on the Activity of Tropical Cyclones Affecting China

In this study, tropical cyclone data from China Meteorological Administration （CMA） and the ECMWF reanalysis data for the period 1958-2001 was used to propose a possible mechanism for the impacts of air- sea interaction on the activity of tropical cyclones （TCs） affecting China. The frequency of TCs affecting China over past 40 years has trended downward, while during the same period, the air sea interaction in the two key areas of the Pacific region has significantly weakened. Our diagnoses and simulations suggest that air sea interactions in the central North Pacific tropics and subtropics （Area 1） have an important role in adjusting typhoon activities in the Northwest Pacific in general, and especially in TC activity affecting China. On the contrary, impacts of the air-sea interaction in the eastern part of the South Pacific tropics （Area 2） were found to be rather limited. As both observational analysis and modeling studies show that, in the past four decades and beyond, the weakening trend of the latent heat released from Area 1 matched well with the decreasing Northwest Pacific TC frequency derived from CMA datasets. Results also showed that the weakening trend of latent heat flux in the area was most likely due to the decreasing TC frequency over the Northwest Pacific, including those affecting China. Although our preliminary analysis revealed a possible mechanism through which the air sea interaction may adjust the genesis conditions for TCs, which eventually affect China, other relevant questions, such as how TC tracks and impacts are affected by these trends, remain unanswered. Further in-depth investigations are required.

Impact of Drug-Drug Interaction between CDK4/6 Inhibitors and Proton Pump Inhibitors on Survival Outcomes in the Treatment of Metastatic Breast Cancer—Real World Data from a Portuguese Center

Introduction: Proton pump inhibitors (PPi) are widely prescribed, including in patients undergoing treatment for advanced breast cancer (ABC). Due to the pharmacokinetic characteristics of the CDK4/6 inhibitor (Ci) palbociclib a drug interaction with PPi was hypothesized. It was shown in a retrospective study that this association was an independent predictive factor for worse progression-free survival (PFS). Objective: To verify the impact of concomitant administration of PPi with Ci on overall survival (OS) and PFS. Material and Methods: This is a retrospective cohort study of patients treated with Ci for HR+HER2-ABC in the period from Feb/2017 to Aug/2020. SPSS software was used for data processing. Univariate analysis was done by the Kaplan-Meier method and log-rank test, and multivariate analysis by COX regression. P-value < 0.05 was considered significant. Results: 80 patients were included. The median age at diagnosis of ABC was 56 years (25 - 75). Treatment with Ci was 1st line for ABC in 68.8%. Choice of Ci was palbociclib in 73.8% (n = 59) and ribociclib in 26.3% (n = 21). The hormone partner was a nonsteroidal aromatase inhibitor in 45.0%, and fulvestrant in 55.0% of cases. 37.5% of patients were on PPi, and 70.0% of them were during the entire treatment (23.3% omeprazole, 73.4% pantoprazole, 3.3% others). Patients taking concomitant PPi and Ci had lower OS (OS-3 years 42.6% vs. 63.4%, p = 0.254) and PFS (PFS med 15 m. vs. 21 m., p = 0.733), although with no statistically significant difference. Discussion: In the sample, there was a numerical difference, without the statistical significance in the use of PPi in the survival of patients under Ci. This difference could be more evident with a longer follow-up and a larger sample size. This study intends to alert to the growing importance of checking for drug interactions. Polymedication, advanced age and the presence of several comorbidities are real problems in patients with ABC. Conclusion: Real-world data from this center demonstrate a negative, non-statistically significant impact of PPi treatment on survival outcomes, in patients treated with Ci for HR+HER2-ABC.

Influence of railway wheel tread damage on wheel-rail impact loads and the durability of wheelsets

Dynamic wheel-rail contact forces induced by a severe form of wheel tread damage have been measured by a wheel impact load detector during full-scale field tests at different vehicle speeds.Based on laser scanning,the measured three-dimensional damage geometry is employed in simulations of dynamic vehicle-track interaction to calibrate and verify a simulation model.The relation between the magnitude of the impact load and various operational parameters,such as vehicle speed,lateral position of wheel-rail contact,track stiffness and position of impact within a sleeper bay,is investigated.The calibrated model is later employed in simulations featuring other forms of tread damage;their effects on impact load and subsequent fatigue impact on bearings,wheel webs and subsurface initiated rolling contact fatigue of the wheel tread are assessed.The results quantify the effects of wheel tread defects and are valuable in a shift towards condition-based maintenance of running gear,and for general assessment of the severity of different types of railway wheel tread damage.

The effect of wax coating,aluminum and ammonium perchlorate on impact sensitivity of HMX

Interaction of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane(HMX)/ammonium perchlorate(AP) and its effect on mechanical sensitivity may result in some restrictions for the application of AP/HMX system in high energetic weapon system. In this work, impact sensitivity test is used to study the effects of wax coating of HMX, AP and aluminum(Al) powder on sensitivity properties of HMX/AP/Al mixtures.Thermogravimetry-differential scanning calorimetry(TG-DSC) analysis has been developed to investigate the mechanism of interaction between HMX and AP during the course of thermal decomposition of HMX/AP/AI mixtures. The results show that severe interaction effect exists between AP and HMX, which causes the impact sensitivity(H_(50)) to become smaller. The impact energy(E_(50)) of mixture can be improved under the circumstances of effective separating HMX from AP by surface coating with Wax. AP may firstly engender low-temperature decomposition under the circumstance of external heat or mechanical impact, which causes the exothermic peak of HMX forward shift about 28 C. The gaseous product releasing from thermal decomposition of HMX accelerates further decomposition of AP. For HMX/AP composite system, the interactive catalysis effect between AP and HMX can be eliminated mostly by adding a great deal of Al powder(i.e. above 30%).

Dynamic Response of Falling Liquid Storage Container Under Transient Impact

The dynamic response performance of a large,cylindrical,fluid-filled steel container under high-speed impact is evaluated through fluid-structure interaction analysis using arbitrary Lagrange-Eulerian(ALE)method.The ALE method is adopted to accurately calculate the structural behavior induced by the internal liquid impact of the container.The stress and strain results obtained from the finite element analysis are in line with the experimental shell impact data.The influences of drop angle,drop height,and flow impact frequency are discussed.Calculation results indicate that the impact stress and damage of the container increase with drop height.However,the amplitude of the oscillation and the impact stress increase when the container and flow impact resonance occur at a certain drop height.The impact stress shows a nonlinear relationship with drop angle.

MPS-FEM Coupled Method for Study of Wave-Structure Interaction

Nowadays,an increasing number of ships and marine structures are manufactured and inevitably operated in rough sea.As a result,some phenomena related to the violent fluid-elastic structure interactions(e.g.,hydrodynamic slamming on marine vessels,tsunami impact on onshore structures,and sloshing in liquid containers)have aroused huge challenges to ocean engineering fields.In this paper,the moving particle semi-implicit(MPS)method and finite element method(FEM)coupled method is proposed for use in numerical investigations of the interaction between a regular wave and a horizontal suspended structure.The fluid domain calculated by the MPS method is dispersed into fluid particles,and the structure domain solved by the FEM method is dispersed into beam elements.The generation of the 2D regular wave is firstly conducted,and convergence verification is performed to determine appropriate particle spacing for the simulation.Next,the regular wave interacting with a rigid structure is initially performed and verified through the comparison with the laboratory experiments.By verification,the MPS-FEM coupled method can be applied to fluid-structure interaction(FSI)problems with waves.On this basis,taking the flexibility of structure into consideration,the elastic dynamic response of the structure subjected to the wave slamming is investigated,including the evolutions of the free surface,the variation of the wave impact pressures,the velocity distribution,and the structural deformation response.By comparison with the rigid case,the effects of the structural flexibility on wave-elastic structure interaction can be obtained.

Evaluation of vertical impact factor coefficients for continuous and integral railway bridges under high-speed moving loads

In the railway bridge analysis and design method,dynamic train loads are regarded as static loads enhanced by an impact factor(IF).The IF coefficients for various railway bridges have been reported as a function of span length or frequency of the bridges in Eurocode(2003).However,these IF coefficient values neglect the effects of very high speeds(>200 km/h)and soil-structure interaction(SSI).In this work,a comprehensive study to assess the impact factor coefficients of mid-span vertical displacements for continuous and integral railway bridges subjected to high-speed moving loads is reported.Three different configurations,each for the three-dimensional(3D)continuous and integral bridge,are considered.Also,single-track(1-T)and two-track(2-T)“real train”loading cases for both these bridge types are considered.Subsequently,finite element analysis of the full-scale 3D bridge models,to identify their IF values,considering the effects of SSI for three different soil conditions,is conducted.The IF values obtained from the study for both bridge types are comparable and are greater than the values recommended by Eurocode(2003).The results reveal that with a loss of soil stiffness,the IF value reduces;thus,it confirms the importance of SSI analysis.

Impact vibration properties of locally resonant fluid-conveying pipes

Fluid-conveying pipe systems are widely used in various equipments to transport matter and energy.Due to the fluid–structure interaction effect,the fluid acting on the pipe wall is easy to produce strong vibration and noise,which have a serious influence on the safety and concealment of the equipment.Based on the theory of phononic crystals,this paper studies the vibration transfer properties of a locally resonant(LR)pipe under the condition of fluid–structure interaction.The band structure and the vibration transfer properties of a finite periodic pipe are obtained by the transfer matrix method.Further,the different impact excitation and fluid–structure interaction effect on the frequency range of vibration attenuation properties of the LR pipe are mainly considered and calculated by the finite element model.The results show that the existence of a low-frequency vibration bandgap in the LR pipe can effectively suppress the vibration propagation under external impact and fluid impact excitation,and the vibration reduction frequency range is near the bandgap under the fluid–structure interaction effect.Finally,the pipe impact experiment was performed to verify the effective attenuation of the LR structure to the impact excitation,and to validate the finite element model.The research results provide a technical reference for the vibration control of the fluid-conveying pipe systems that need to consider blast load and fluid impact.

Accurate estimation of line-of-sight rate under strong impact interference effect

In the process of the terminal guidance of a kinetic kill vehicle(KKV),it is very important to accurately estimate the lineof-sight(LOS)rate via the measurements of a target seeker onboard the KKV.The strong impact interference caused by the large lateral thrust produced by the thrusters on the KKV is a main factor that affects the measurements on the LOS angle.A method to estimate the impact interference and the LOS rate together via a Kalman filter is proposed to improve the estimation precision of the LOS rate.The observability of the system describing the missile-target relative motion model and the impact interference model is proved,and then a Kalman filter is designed.In the Kalman filter design,the continuous-discrete and two-stage filtering techniques are used because the system model is time-variant and high-order.Numerical simulation results show that by estimating the impact interference,the estimation precision of the LOS rate is increased,and so the miss distance of the KKV under the strong impact interference is reduced.The proposed continuous-discrete two-stage Kalman filter shows higher estimation precision and lower computational cost than the naive discrete augmented state Kalman filter.

Numerical Simulations of Pile Supported Protective System Subjected to Ship Impact

The head-on collision process between ship and concrete pile supported protective system is simulated by software LS-DYNA. The influences of pile non-linearity and soil non-linearity on impact force, ship crush depth and the cap displacement of pile supported protective system are discussed. It's shown that for both severe impact case and non-severe impact case, the non-linearity of pile material influence the impact force history, ship crush depth. The non-linearity of pile material and soil has remarkable influence on the cap displacement especially for severe impact case. These issues should not be ignored in the analysis of pile supported protective system subjected to ship impact.

Dynamic Impact Factor Induced by Idling Vehicle-Bridge Coupling Vibration

To analyze the impact effect induced by vehicle-bridge coupling vibration during traffic congesting, hundreds and thousands of congestion scenarios consisting of various vehicle platoons were collected and used to develop vehicle models as well as traffic congestion load models. Furthermore, the idling vehicle-bridge coupling model was established by the finite element method and the congestion models were applied to calculate dynamic impact factors. Compared with the value specified in Chinese codes, the calculated values were 1.15-2.67 times as large as the latter, which indicates the impact factors caused by idling vehicle-bridge coupling under congestion situations were much larger than those in normal traffic conditions. As a result, a calibration factor of 1.7 was recommended for bridge design or evaluation when considering vehicle-bridge coupling vibration under heavy traffic congestion. The proposed analytical model, analysis method, and results could also be beneficial references to further investigation in this field.

Dynamic Calculation Method of Beam System Under Low Velocity Impact

The bearing beams and the supporting beams under low velocity impact may be in four different strain stages of deformation depending on the impact intensity and beam structure strength.Based on the different judging conditions of deformation stages,the corresponding calculation models are proposed,the calculation formulae for the determination of the impact force and the beam's lateral displacement are obtained.Calculation shows that the beam's total deflection is small when the flexibility of the supporting component is high and the effect of diminishing deflection disappears almost when the stiffness of the supporting component is high.

A TIME DOMAIN BOUNDARY ELEMENT METHOD FOR WATER-SOLID IMPACT ANALYSIS

A reciprocal theorem of dynamics for potential flow problems is first derived by means of the Laplace transform in which the compressibility of water is taken into account. Based on this theorem, the corresponding time-space boundary integral equation: is obtained. Then, a set of time domain boundary element equations with recurrence form is immediately formulated through discretization in both time and boundary. After having carried out the numerical calculation two solutions are found in which a rigid semicircular cylinder and a rigid wedge with infinite length suffer normal impact on the surface of a half-space fluid. The results show that the present method is more efficient than the previous ones.

A Numerical Study on the Water Impact of the Rigid/Elastic Box-Like Structure

Recent damages to the box-like structures caused by wave slamming have made it necessary to study the impact problems of this kind of structure. This paper showed findings from numerical simulations of the rigid/elastic structures, aiming to gain insights into the characteristics of the problem. The results of the rigid cases showed the significance of air compressibility during the impact process, while the slamming phenomena became quite different without the effect. In the elastic cases, the trapped air made the structure vibrate at frequencies much smaller than its eigenfrequencies. Besides, the structural deformation made it easy for the trapped air to escape outwards, which weakened the air cushioning effect, especially at high impact velocities. The above analysis gives the results when the structural symmetry axis was vertical to the water(vertical impacts). In addition, the results were given when the axis was oblique to the water(oblique impacts). Compared with the vertical cases, the impact phenomena and structural response showed asymmetry. This work used the computational fluid dynamics(CFD) method to describe fluid motion and the finite element method(FEM) for the deformable structure. A two-way coupling approach was used to deal with the fluid-structure interaction in the elastic cases.

Numerical Simulation on Hydroelastic Response of Structure under Impact Load from Water Using Eulerian Scheme with Lagrangian Particles

Hydroelasticity caused by water impact is of concem in many applications of ocean engineering/naval architect and is a complicated physical phenomenon. The authors have developed a coupled Eulerian scheme with Lagrangian particles to combine advantages and to compensate disadvantages in both grid based method and particle based method. In this study, the developed numerical model was applied to hydroelastic problems due to impact pressure such as water entry of an elastic cylinder and elastic tanker motion in wave. The authors showed the numerical results which is overall agreement with experimental results. The proposed numerical scheme can be useful and effectiveness to evaluate hydroelasticity and ship-wave interaction in nonlinear wave motion with breaking.

高速跨介质入水多相流动与流固耦合特性研究综述

高速跨介质入水问题广泛存在于海洋工程、航空航天等领域,入水多相流动与流固耦合作用机理是该领域的研究热点,对于跨介质航行器的载荷预报、弹道稳定性评估、结构强度校核以及安全性设计等具有重要意义。本文围绕高速跨介质入水所涉及的基础关键力学问题,重点论述了高速跨介质多相流动与空泡演化、冲击载荷与降载方法、运动稳定性与流固耦合响应、流固耦合数值研究方法等方面的研究现状,并针对目前仍存在的问题提出了建议,旨在为高速跨介质入水的相关研究与设计等提供参考。

INTERANNUAL OSCILLATION OF MERIDIONAL SEA LEVEL WIND AND ITS IMPACT ON SEA SURFACE TEMPERATURE IN THE SOUTH CHINA SEA

Analysis of COADS data(1958- 1987) showed that there is obviously interannual SST oscillation including QBO (Quasi-biennial oscillation ) and quasi-3.5 year oscilation , etc ., of the SCS (South China Sea), which is the response of the the upper mixed layer of the sea to the impact of the East Asian Monsoon anomaly . Most SST anomalies appear in the central basin of the SCS.The phase-locked phenomena linking the SST annual cycle and interannual oscillation in an important characteristic of the SCS climate . There is not only SST response to atmospheric impact , but also feedback to the air . The authors put forward a scheme of regional air-sea interaction in winter time in the SCS.

多馈入直流输电系统后续换相失败安全裕度评估及抑制方法

换相失败可能引起直流输电系统(line commutated converter based high voltage direct current,LCC-HVDC)闭锁,严重影响电网的安全稳定运行。多馈入直流输电系统中电气耦合紧密,控制响应造成多回LCC-HVDC交互影响,使换相失败的产生机理变得更加复杂。现有后续换相失败抑制方法多以单回LCC-HVDC为对象,无法兼顾自身换相恢复和相邻直流换相失败抑制的需求。为此,提出了一种适应于多馈入直流输电系统的后续换相失败抑制方法。分析了LCC-HVDC首次换相失败恢复过程中逆变站控制系统的响应时序及条件,提出了考虑故障严重程度和LCC-HVDC控制影响的后续换相失败安全裕度评估方法,进而提出了基于电压安全裕度的后续换相失败抑制方法,并在CIGRE HVDC标准测试系统验证了所提方法的有效性。仿真结果表明,所提方法根据换流母线电压自适应地调节直流电流,能够有效降低多馈入直流输电系统中无功电压耦合影响,有效抑制相邻回LCC-HVDC发生后续换相失败。