We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland. The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito. The ...We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland. The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito. The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans. Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream. The mother ceased breastfeeding and took oral terbinafine for 4 weeks. No recurrence was observed in the infant during 12 months of follow-up.展开更多
To investigate the effects of Ginkgo paste for external use on tinea corporis in a guinea pig model.The guinea pig tinea corporis model were induced by infection with Trichophyton mentagrophytes strains.And then,high ...To investigate the effects of Ginkgo paste for external use on tinea corporis in a guinea pig model.The guinea pig tinea corporis model were induced by infection with Trichophyton mentagrophytes strains.And then,high and low doses of Ginkgo water-paste and alcohol-paste were administrated to the animals.The symptom,tinea corporis skin lesions and histopathological aspects of guinea pig were analyzed.High and low doses of Ginkgo alcohol-paste and Ginkgo water-paste could significantly reduced the tinea corporis symptom(P<0.01),increased negative rate of strain culture(P<0.01),and improved pathological changes of tinea corporis(P<0.01).The best efficacy was observed in high dose ginkgo alcohol paste group.These results suggest that Ginkgo paste exhibits the efficacy to treat tinea corporis in a guinea pig model.展开更多
A 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. During that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermati...A 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. During that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermatitis at other hospitals, and had been treated with agents that included acitretin and prednisone. Finally, fungi were found in the lesions by optical microscopy, and the fungal culture was positive for Microsporum gypseum, and was diagnosed as a Microsporum gypseum infection. The lesions eventually cleared completely after 8 weeks of antifungal treatment.展开更多
Objective: To determine the epidemiology and the aetiology of tinea capitis in the elderly in Turin (Italy). Methods: We prospectively collected all cases of adult tinea capitis in the Dermatology Clinic of the Univer...Objective: To determine the epidemiology and the aetiology of tinea capitis in the elderly in Turin (Italy). Methods: We prospectively collected all cases of adult tinea capitis in the Dermatology Clinic of the University of Turin from January 1997 to December 2012. Results: 13 patients (4 males and 9 females) with a mean age of 56.5 years were found to be affected by tinea capitis among a total number of 508 (2.6%). Diagnosis was made on clinical appearance and mycological examination. Culture identified M. canis in 7 patients (53.8%), T. mentagrophytes in 3 patients (23.1%), T. rubrum in 2 patients (15.4%) and T. violaceum in 1 patient (7.7%). 6 cases reported contact with animals. Treatment consisted in administration of Griseofulvin at the dose of 500 mg/d or Terbinafine at the dose of 250 mg/d for at least 8 weeks. A complete recovery was observed in 10 patients, whereas 3 of them suffered from cicatritial alopecia. Conclusion: This study wants to highlight the importance of considering tinea capitis as a differential diagnosis in elderly patients with scaly scalp lesions, even though it is considered to be rare in adults.展开更多
The zoophylic dermatophytes, as Trichophyton erinacei, frequently cause very inflammatory tineas in the human host. This dermatophyte is carried by some pets, particularly by the terrestrial hedgehog. Herein, we prese...The zoophylic dermatophytes, as Trichophyton erinacei, frequently cause very inflammatory tineas in the human host. This dermatophyte is carried by some pets, particularly by the terrestrial hedgehog. Herein, we present the case of a 22-year-old male student with an exudative erythematous scaly plaque on his right fifth finger for 1 month. He had a pet African hedgehog (Atelerix albiventris). KOH examination demonstrated hyphae compatible with dermatophytes. The culture revealed a white, radiated dusty colony. PCR sequencing of the region ITS1-5.8S-ITS2 identified T. erinacei. The final diagnosis was inflammatory tinea manuum due to T. erinacei. Clinical and mycological cure was achieved after treatment with oral terbinafine 250 mg/day × 1 month.展开更多
This prospective, open-label, single-arm investigation evaluated the performance of a multifunctional foot cream used twice daily for 8 weeks in the combined treatment of mild/moderate tinea pedis interdigitalis (TPI)...This prospective, open-label, single-arm investigation evaluated the performance of a multifunctional foot cream used twice daily for 8 weeks in the combined treatment of mild/moderate tinea pedis interdigitalis (TPI) and heel cracks, calluses and/or dry feet in 46 adult subjects. All subjects showed reductions in the severity of symptoms of both TPI (53.7% reduction) and heel cracks, calluses and/or dry feet (51.6% reduction), beginning already after 2 weeks of treatment, with reduction continuation and improvement after 4 and 8 weeks of treatment. Negative mycological cultures were obtained post-treatment in 85.7% of subjects, while 35.7% of subjects also obtained mycological cure (negative mycological culture + negative KOH test). Post-treatment questionnaires showed improved quality of life, good treatment tolerability, easy use, and that 69% of subjects would recommend the product. The results reveal that the foot cream is safe and effective in the combined treatment of TPI and heel cracks, calluses and/or dry feet.展开更多
Introduction:Tinea of vellus hair is a rare dermatophytosis,caused by dermatophyte infection in the vellus hair.The clinical symptoms of tinea of vellus hair are more serious and the conventional topical treatment are...Introduction:Tinea of vellus hair is a rare dermatophytosis,caused by dermatophyte infection in the vellus hair.The clinical symptoms of tinea of vellus hair are more serious and the conventional topical treatment are often ineffective.Here,we report a case of tinea of vellus hair caused by Trichophyton violaceum in a child.Case presentation:A 7-year-old boy presented with a localized,scaly,and itchy erythema on his left cheek for two months.He once used a topical corticosteroid but without any clinical improvement,the erythema was progressively enlarging and spread to the left eyebrow.He denied any contact with animals.Direct microscopy found abundant spores and hyphae on the vellus hair;T.violaceum was identified by culture and PCR examination.The patient was diagnosed with tinea of vellus hair and cured after treating with oral terbinafine 125 mg/day and topical treatment for two weeks.There was no recurrence during the follow-up period.Discussion:The clinical symptoms of tinea of vellus hair are often atypical and easy to be misdiagnosed.Timely fungal examination is necessary for suspicious patients and confirmed patients should be treated with oral antifungal drugs.Conclusion:The diagnosis and treatment of tinea of vellus hair need to be paid more attention in clinical works.展开更多
文摘We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland. The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito. The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans. Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream. The mother ceased breastfeeding and took oral terbinafine for 4 weeks. No recurrence was observed in the infant during 12 months of follow-up.
基金National“11th Five-Year”support program(2008BAI53B09)university science and technology innovation team(2012IRTSTHN011)Zhengzhou science and technology innovation team plan(131PCXTD612).
文摘To investigate the effects of Ginkgo paste for external use on tinea corporis in a guinea pig model.The guinea pig tinea corporis model were induced by infection with Trichophyton mentagrophytes strains.And then,high and low doses of Ginkgo water-paste and alcohol-paste were administrated to the animals.The symptom,tinea corporis skin lesions and histopathological aspects of guinea pig were analyzed.High and low doses of Ginkgo alcohol-paste and Ginkgo water-paste could significantly reduced the tinea corporis symptom(P<0.01),increased negative rate of strain culture(P<0.01),and improved pathological changes of tinea corporis(P<0.01).The best efficacy was observed in high dose ginkgo alcohol paste group.These results suggest that Ginkgo paste exhibits the efficacy to treat tinea corporis in a guinea pig model.
文摘A 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. During that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermatitis at other hospitals, and had been treated with agents that included acitretin and prednisone. Finally, fungi were found in the lesions by optical microscopy, and the fungal culture was positive for Microsporum gypseum, and was diagnosed as a Microsporum gypseum infection. The lesions eventually cleared completely after 8 weeks of antifungal treatment.
文摘Objective: To determine the epidemiology and the aetiology of tinea capitis in the elderly in Turin (Italy). Methods: We prospectively collected all cases of adult tinea capitis in the Dermatology Clinic of the University of Turin from January 1997 to December 2012. Results: 13 patients (4 males and 9 females) with a mean age of 56.5 years were found to be affected by tinea capitis among a total number of 508 (2.6%). Diagnosis was made on clinical appearance and mycological examination. Culture identified M. canis in 7 patients (53.8%), T. mentagrophytes in 3 patients (23.1%), T. rubrum in 2 patients (15.4%) and T. violaceum in 1 patient (7.7%). 6 cases reported contact with animals. Treatment consisted in administration of Griseofulvin at the dose of 500 mg/d or Terbinafine at the dose of 250 mg/d for at least 8 weeks. A complete recovery was observed in 10 patients, whereas 3 of them suffered from cicatritial alopecia. Conclusion: This study wants to highlight the importance of considering tinea capitis as a differential diagnosis in elderly patients with scaly scalp lesions, even though it is considered to be rare in adults.
文摘The zoophylic dermatophytes, as Trichophyton erinacei, frequently cause very inflammatory tineas in the human host. This dermatophyte is carried by some pets, particularly by the terrestrial hedgehog. Herein, we present the case of a 22-year-old male student with an exudative erythematous scaly plaque on his right fifth finger for 1 month. He had a pet African hedgehog (Atelerix albiventris). KOH examination demonstrated hyphae compatible with dermatophytes. The culture revealed a white, radiated dusty colony. PCR sequencing of the region ITS1-5.8S-ITS2 identified T. erinacei. The final diagnosis was inflammatory tinea manuum due to T. erinacei. Clinical and mycological cure was achieved after treatment with oral terbinafine 250 mg/day × 1 month.
文摘This prospective, open-label, single-arm investigation evaluated the performance of a multifunctional foot cream used twice daily for 8 weeks in the combined treatment of mild/moderate tinea pedis interdigitalis (TPI) and heel cracks, calluses and/or dry feet in 46 adult subjects. All subjects showed reductions in the severity of symptoms of both TPI (53.7% reduction) and heel cracks, calluses and/or dry feet (51.6% reduction), beginning already after 2 weeks of treatment, with reduction continuation and improvement after 4 and 8 weeks of treatment. Negative mycological cultures were obtained post-treatment in 85.7% of subjects, while 35.7% of subjects also obtained mycological cure (negative mycological culture + negative KOH test). Post-treatment questionnaires showed improved quality of life, good treatment tolerability, easy use, and that 69% of subjects would recommend the product. The results reveal that the foot cream is safe and effective in the combined treatment of TPI and heel cracks, calluses and/or dry feet.
文摘Introduction:Tinea of vellus hair is a rare dermatophytosis,caused by dermatophyte infection in the vellus hair.The clinical symptoms of tinea of vellus hair are more serious and the conventional topical treatment are often ineffective.Here,we report a case of tinea of vellus hair caused by Trichophyton violaceum in a child.Case presentation:A 7-year-old boy presented with a localized,scaly,and itchy erythema on his left cheek for two months.He once used a topical corticosteroid but without any clinical improvement,the erythema was progressively enlarging and spread to the left eyebrow.He denied any contact with animals.Direct microscopy found abundant spores and hyphae on the vellus hair;T.violaceum was identified by culture and PCR examination.The patient was diagnosed with tinea of vellus hair and cured after treating with oral terbinafine 125 mg/day and topical treatment for two weeks.There was no recurrence during the follow-up period.Discussion:The clinical symptoms of tinea of vellus hair are often atypical and easy to be misdiagnosed.Timely fungal examination is necessary for suspicious patients and confirmed patients should be treated with oral antifungal drugs.Conclusion:The diagnosis and treatment of tinea of vellus hair need to be paid more attention in clinical works.
