Assessing cutter-rock interaction during TBM tunnelling in granite:Large-scale standing rotary cutting tests and 3D DEM simulations

The widespread utilisation of tunnel boring machines(TBMs)in underground construction engineering requires a detailed investigation of the cutter-rock interaction.In this paper,we conduct a series of largescale standing rotary cutting tests on granite in conjunction with high-fidelity numerical simulations based on a particle-type discrete element method(DEM)to explore the effects of key cutting parameters on the TBM cutter performance and the distribution of cutter-rock contact stresses.The assessment results of cutter performance obtained from the cutting tests and numerical simulations reveal similar dependencies on the key cutting parameters.More specifically,the normal and rolling forces exhibit a positive correlation with penetration but are slightly influenced by the cutting radius.In contrast,the side force decreases as the cutting radius increases.Additionally,the side force shows a positive relationship with the penetration for smaller cutting radii but tends to become negative as the cutting radius increases.The cutter's relative effectiveness in rock breaking is significantly impacted by the penetration but shows little dependency on the cutting radius.Consequently,an optimal penetration is identified,leading to a low boreability index and specific energy.A combined Hertz-Weibull function is developed to fit the cutter-rock contact stress distribution obtained in DEM simulations,whereby an improved CSM(Colorado School of Mines)model is proposed by replacing the original monotonic cutting force distribution with this combined Hertz-Weibull model.The proposed model outperforms the original CSM model as demonstrated by a comparison of the estimated cutting forces with those from the tests/simulations.The findings from this work that advance our understanding of TBM cutter performance have important implications for improving the efficiency and reliability of TBM tunnelling in granite.

Landslide model tests with a miniature 2D principal stress sensor

Understanding the stress distribution derived from monitoring the principal stress(PS)in slopes is of great importance.In this study,a miniature sensor for quantifying the two-dimensional(2D)PS in landslide model tests is proposed.The fundamental principle and design of the sensor are demonstrated.The sensor comprises three earth pressure gages and one gyroscope,with the utilization of three-dimensional(3D)printing technology.The difficulties of installation location during model preparation and sensor rotation during testing can be effectively overcome using this sensor.Two different arrangements of the sensors are tested in verification tests.Additionally,the application of the sensor in an excavated-induced slope model is tested.The results demonstrate that the sensor exhibits commendable performance and achieves a desirable level of accuracy,with a principal stress angle error of±5°in the verification tests.The stress transformation of the slope model,generated by excavation,is demonstrated in the application test by monitoring the two miniature principal stress(MPS)sensors.The sensor has a significant potential for measuring primary stress in landslide model tests and other geotechnical model experiments.

Model tests and numerical analysis of emergency treatment of cohesionless soil landslide with quick-setting polyurethane

Shotcrete is one of the common solutions for shallow sliding.It works by forming a protective layer with high strength and cementing the loose soil particles on the slope surface to prevent shallow sliding.However,the solidification time of conventional cement paste is long when shotcrete is used to treat cohesionless soil landslide.The idea of reinforcing slope with polyurethane solidified soil(i.e.,mixture of polyurethane and sand)was proposed.Model tests and finite element analysis were carried out to study the effectiveness of the proposed new method on the emergency treatment of cohesionless soil landslide.Surcharge loading on the crest of the slope was applied step by step until landslide was triggered so as to test and compare the stability and bearing capacity of slope models with different conditions.The simulated slope displacements were relatively close to the measured results,and the simulated slope deformation characteristics were in good agreement with the observed phenomena,which verifies the accuracy of the numerical method.Under the condition of surcharge loading on the crest of the slope,the unreinforced slope slid when the surcharge loading exceeded 30 k Pa,which presented a failure mode of local instability and collapse at the shallow layer of slope top.The reinforced slope remained stable even when the surcharge loading reached 48 k Pa.The displacement of the reinforced slope was reduced by more than 95%.Overall,this study verifies the effectiveness of polyurethane in the emergency treatment of cohesionless soil landslide and should have broad application prospects in the field of geological disasters concerning the safety of people's live.

基于TestStand的DDS特性参数自动测试管理

介绍了基于TestStand软件对DDS特性参数进行自动化测试的流程管理。DDS测试参数包括常规参数和特性参数,常规参数由普通的专用测试设备即可测试,而特性参数由于测试项目繁多,测试要求高,采用普通的测试设备难以测全所有参数,且精度难以保证,通过外接高性能专用仪器对其测试是比较好的测试方案。由此带来的问题是测试资源杂多,需要一个统一的测试管理平台,对测试资源和测试流程做统一的测试管理。TestStand软件是一款非常优秀的测试管理软件,应用TestStand软件对DDS复杂的自动测试流程进行管理,方便了测试开发过程,极大地提高了测试开发效率。

基于TestStand的测试系统及应用

本文首先介绍了测试管理环境TestStand的基本概念和系统结构 ,进而介绍了基于TestStand开发测试系统的流程。在本文的最后 ,给出了这种测试系统的应用。

基于TestStand的TPS开发设计

阐述了自动测试系统(ATS)在电子设备测试维修领域的重要性和发展趋势,介绍了测试程序集(TPS)在ATS中的重要性。描述了TPS和通用检测平台的组成及功能。以视频输出设备为例,在分析其测试需求的基础上设计了被测单元接口适配器(TUA),并采用TestStand与VC++相结合的方式设计了测试程序(TP)。最后在实际使用中验证了TPS具有对视频输出设备功能测试和故障诊断隔离的能力。

基于TestStand的分机性能自动测试的开发应用

应用基于TestStand的强大功能和集成的自动测试环境,为装备的每一个分机开发了一套性能指标自动测试应用程序。通过此开发应用,可以在装备的研发、生产、维修保障中,详细了解每个分机的工作状态,同时也为分机的故障维修提供了检测手段。相比以往的分机性能测试,此系统的开发,使分机的检测操作变得简单、快捷、高效。

基于TestStand的分机自动故障诊断系统

在装备的维修保障中,如何快速准确地把装备中分机的故障诊断出来,需要具备扎实的专业知识、技能和经验,这些都给维修保障人员提出了很高的要求。针对这一问题,应用基于TestStand的强大的自动测试及测试序列管理的功能,为装备里的每一个分机开发了一套自动故障诊断系统,给装备维修人员提供了一个自动化和智能化的诊断工具,操作简单明了,在实际运用中,效果显著。

基于TestStand的医疗仪器产品性能自动测试系统研制

为解决传统人工测量方式对电子医疗仪器产品板卡性能检验中测量效率低、测量不准确和测量手段复杂等问题,提高生产效率和板卡的质量控制,对虚拟仪器技术以及自动测试系统技术进行了研究;研制开发了一种基于TestStand和LabVIEW的电子产品性能自动测试系统;自动测试系统通过控制TestStand引擎调用待测试板卡的测试序列实现对不同板卡的测试,测试序列是由各测量程序配置组成;设计的测试参数集中配置、项目分组测试以及测试产品目录自动生成方案,提高了系统的通用性、扩展性以及灵活性;实验和实际应用表明,该系统在应用中具有很高的测试效率和测量准确性并且操作简便。

Inflow and outflow permeability tests in a very soft clay under low stresses

In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,especially in the case of very soft clays under low stresses.Pore pressures were monitored during probe installation and were found to be slightly lower than piezocone u2 pore pressures,consistent with the position of the filter.The role of filter tip saturation was investigated after the usual saturation procedure provided an unsatisfactory pore pressure response during probe installation.Results show that the vacuum saturation procedure provides adequate response during installation and increases the reliability of the coefficient of permeability determination in early measurements.Both inflow and outflow tests yielded similar results,indicating that careful execution of the test can lead to good test repeatability regardless of the loading condition.Various sequences of alternated inflow and outflow tests have yielded similar results,indicating that soil reconsolidation and filter clogging were negligible in the tests performed.Data are presented concerning the relationship between index parameters and the in situ coefficient of permeability for SarapuíII clay,which plot outside the range of existing databases.

Real-world utility of serological tests in patients with suspected scrub typhus in the Republic of Korea:A single-center,retrospective,observational study

Objective:Serological tests are widely used for scrub typhus diagnosis;however,their limitations are evident.This study aims to assess their practical value in clinical settings.Methods:We analyzed the data of adult patients with suspected scrub typhus who visited a tertiary care hospital in the Republic of Korea from September to December from 2019 to 2021.The included patients had an acute fever and at least one of the following ten secondary findings:myalgia,skin rash,eschar,headache,thrombocytopenia,increased liver enzyme levels,lymphadenopathy,hepatomegaly,splenomegaly,and pleural effusion.The diagnoses were grouped as scrub typhus or other diseases by two infectious disease physicians.Results:Among 136 patients who met the eligibility criteria,109 had scrub typhus and 27 had different diseases.Single and paired total antibodies using immunofluorescence assay(IFA),and total antibodies using immunochromatography-based rapid diagnostic testing(ICT)were measured in 98%,22%,and 75%of all patients,respectively.Confirmation using paired samples for scrub typhus was established at a median of 11[interquartile range(IQR)10-16]days following the first visit.Among the 82 admitted patients,the median admission time was 9(IQR 7-13)days.According to IFA,58(55%)patients with scrub typhus had total immunoglobulin titers≥1:320,while 23(85%)patients with other disease had titers<1:320.Positive ICT results were observed in 64(74%)patients with scrub typhus and 10(67%)patients with other diseases showed negative ICT results.Conclusions:Serological testing for scrub typhus is currently insufficient for decision-making in clinical practice.

A Practical Guide to Statistical Tests in the Biomedical Field: From Parametric to Nonparametric, Where and How?

Healthcare decisions are based on scientific evidence obtained from medical studies by gathering data and analyzing it to obtain the best results. When analyzing data, biostatistics is a powerful tool, but healthcare professionals lack knowledge in this field. This lack of knowledge can manifest itself in situations such as choosing the wrong statistical test for the right situation or applying a statistical test without checking its assumptions, leading to inaccurate results and misleading conclusions. With the help of this “narrative review”, the aim is to bring biostatistics closer to healthcare professionals by answering certain questions: how to describe the distribution of data? how to assess the normality of data? how to transform data? and how to choose between nonparametric and parametric tests? Through this work, our hope is that the reader will be able to choose the right test for the right situation, in order to obtain the most accurate results.

Research on aiming methods for small sample size shooting tests of two-dimensional trajectory correction fuse

The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future.

Presentation of Empirical Equations for Estimating Internal Friction Angle of GW and GC Soils in Mashhad, Iran Using Standard Penetration and Direct Shear Tests and Comparison with Previous Equations

Presentation of empirical equations for estimating engineering properties of soils is a simple, low cost and widely-used method. One of the major concerns in using these equations is evaluating their accuracy in different conditions and regions which often lead to doubts about obtained results. Most of these equations were derived in special laboratories, different climate conditions and in soils with different geotechnical and geological engineering properties and were generalized to other conditions. The main question is that whether these methods are also applicable to other conditions. Using local equations and narrowing the usage range of various methods based on each region’s properties are appropriate methods to solve these problems. This leads to simplified and faster analysis and high reliability in the obtained results. In this paper, empirical equations were derived to estimate internal friction angle, based on SPT numbers of Mashhad City’s soils in Iran, using SPT and direct shear tests results from 50 samples (25 GW and 25 GC soil samples). The results showed similar values for predicted?φ?values by SPT test and?φ?values determined by direct shear tests.

New Stability Tests of Positive Standard and Fractional Linear Systems

New tests for checking asymptotic stability of positive 1D continuous-time and discrete-time linear systems without and with delays and of positive 2D linear systems described by the general and the Roesser models are proposed. Checking of the asymptotic stability of positive 2D linear systems is reduced to checking of suitable corresponding 1D positive linear systems. It is shown that the stability tests can be also applied to checking the asymptotic stability of fractional discrete-time linear systems with delays. Effectiveness of the tests is shown on numerical examples.

基于TestStand的分机故障隔离的开发应用

装备的维修保障需要扎实的专业知识和技能,这对维修保障人员提出了很高的要求。针对这一问题,应用基于TestStand的强大的自动测试序列的功能,为装备的每个分机开发了测试应用程序,给维修保障人员提供了一种简单快捷的方法。

Comparison of RFFIT Tests with Different Standard Sera and Testing Procedures

The World Health Organization （WHO） standard assay for determining antibody level is the rapid fluorescent focus inhibition test （RFFIT） and is used to determine the degree of immunity after vaccination against rabies. To compare the difference in RFFIT results between the laboratories of The National Institute of Infectious Disease in Japan （NIID） and the Chinese Centre for Disease Control （CCDC） as well the influence of the choice of standard serum （STD） for the detection, the two laboratories detection methods were simultaneously manipulated by RFFIT. The reference serums used in NIID and the WHO standard serum used in CCDC were compared in the same RFFIT detection to determine the titer of four sera samples C1, Sl, S2 and S4 in parallel, and the titers of the detected sera samples were calculated using the standard formula for neutralizing antibody titer. No significant difference was found in RFFIT methods from the two laboratories and the RFFIT testing procedures of the two laboratories have good consistency. However, different titers were obtained with the tentative internal standard serum （TI-STD） produced by adjusting to 2.0 IU of WHO standard serum in NIID and the WHO STD. The titer determined with the TI-STD was higher than that determined with WHO STD, This difference appears to be significant and requires further investigation

Resistance of full-scale beams against close-in explosions.Numerical modeling and field tests

This paper explores the performances of a finite element simulation including four concrete models applied to a full-scale reinforced concrete beam subjected to blast loading. Field test data has been used to compare model results for each case. The numerical modelling has been, carried out using the suitable code LS-DYNA. This code integrates blast load routine(CONWEP) for the explosive description and four different material models for the concrete including: Karagozian & Case Concrete, Winfrith, Continuous Surface Cap Model and Riedel-Hiermaier-Thoma models, with concrete meshing based on 10, 15, and 20 mm. Six full-scale beams were tested: four of them used for the initial calibration of the numerical model and two more tests at lower scaled distances. For calibration, field data obtained employing pressure and accelerometers transducers were compared with the results derived from the numerical simulation. Damage surfaces and the shape of rupture in the beams have been used as references for comparison. Influence of the meshing on accelerations has been put in evidence and for some models the shape and size of the damage in the beams produced maximum differences around 15%. In all cases, the variations between material and mesh models are shown and discussed.

Retrospective analysis of discordant results between histology and other clinical diagnostic tests on helicobacter pylori infection

BACKGROUND A reliable test is essential for diagnosing Helicobacter pylori(H.pylori)infection,and crucial for managing H.pylori-related diseases.Serving as an excellent method for detecting H.pylori infection,histologic examination is a test that clinicians heavily rely on,especially when complemented with immunohistochemistry(IHC).Additionally,other diagnostic tests for H.pylori,such as the rapid urease test(CLO test)and stool antigen test(SA),are also highly sensitive and specific.Typically,the results of histology and other tests align with each other.However,on rare occasions,discrepancy between histopathology and other H.pylori diagnostic tests occurs.AIM To investigate the discordance between histology and other H.pylori tests,the underlying causes,and the impact on clinical management.METHODS Pathology reports of gastric biopsies were retrieved spanning August 2013 and July 2018.Reports were included in the study only if there were other H.pylori tests within seven days of the biopsy.These additional tests include CLO test,SA,and H.pylori culture.Concordance between histopathology and other tests was determined based on the consistency of results.In instances where histology results were negative while other tests were positive,the slides were retrieved for re-assessment,and the clinical chart was reviewed.RESULTS Of 1396 pathology reports were identified,each accompanied by one additional H.pylori test.The concordance rates in detecting H.pylori infection between biopsy and other tests did not exhibit significant differences based on the number of biopsy fragments.117 discrepant cases were identified.Only 20 cases(9 with CLO test and 11 with SA)had negative biopsy but positive results in other tests.Four cases initially stained with Warthin-Starry turned out to be positive for H.pylori with subsequent IHC staining.Among the remaining 16 true discrepant cases,10 patients were on proton pump inhibitors before the biopsy and/or other tests.Most patients underwent treatment,except for two who were untreated,and two patients who were lost to follow-up.CONCLUSION There are rare discrepant cases with negative biopsy but positive in SA or CLO test.Various factors may contribute to this inconsistency.Most patients in such cases had undergone treatment.

Optimal Design of High-Speed Partial Flow Pumps using Orthogonal Tests and Numerical Simulations

To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm,special attention was paid to the first and second stage impeller guide vanes.Moreover,the impeller blade outlet width,impeller inlet diameter,blade inclination angle,and number of blades were considered for orthogonal tests.Accordingly,nine groups of design solutions were formed,and then used as a basis for the execution of numerical simulations(CFD)aimed at obtaining the efficiency values and heads for each design solution group.The influence of impeller geometric parameters on the efficiency and head was explored,and the“weight”of each factor was obtained via a range analysis.Optimal structural parameters were finally chosen on the basis of the numerical simulation results,and the performances of the optimized model were verified accordingly(yet by means of CFD).Evidence is provided that the increase in the efficiency and head of the optimized model was 12.11%and 23.5 m,respectively,compared with those of the original model.