Objective:To systematically evaluate the efficacy and safety of traditional Chinese medicine for regulating spleen and kidney.Methods:We developed a search strategy and then retrieved the database including CNKI,Wanfa...Objective:To systematically evaluate the efficacy and safety of traditional Chinese medicine for regulating spleen and kidney.Methods:We developed a search strategy and then retrieved the database including CNKI,Wanfang data knowledge service platform,VIP journals resource integration service platform,PubMed,Embasefor randomized controlled trial of regulating spleen and kidney traditional Chinese medicine compared with conventional western medicine in the treatment of chronic uric acid nephropathy.The search deadline was set to June 30,2020.For the included literature,we applied the cochrane collaboration network risk bias assessment tool to evaluate the methodological quality,and evaluated the level of evidence according to GRADE standards.Quantitative data was analyzed by RevMan5.3 software,and trial sequential analysis method was used to analyze its efficiency.Results:A total of 709 cases in 10 articles were included.Compared with the control group,the related traditional Chinese medicine group improved the effective rate[RR=1.45,95%CI(1.32,1.58)],reduced the level of UA[MD=-36.24,95%CI(-41.03,-31.45)],BUN[SMD=-1.27,95%CI(-1.47,-1.07)]and SCR[MD=-36.33,95%CI(-55.79,-16.87),P=0.0003],the difference between the two groups was statistically significant(P<0.05).There was no evidence that a significant adverse reaction occurred.The results of TSA analysis showed that the Chinese medicine group had definite evidence for improving the efficiency.According to the GRADE evaluation criteria,the efficiency,UA,BUN and SCR outcome indicators were extremely low-quality evidence.Conclusions:Traditional Chinese medicine for regulating spleen and kidney in the treatment of chronic uric acid nephropathy improved efficiency,reduced the level of UA,BUN,SCR.Meanwhile,the therapy was proved to be safe.Nevertheless,the conclusions need further high-quality evidence to support.展开更多
The method of warming the kidney and strengthening the spleen is widely used in the treatment of ulcerative colitis (UC) with significant curative effect.This paper reviews the relevant literature in recent years.
Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second high...Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second highest among peripheral nerve entrapment diseases,and it is one of the common clinical diseases.The theory of liver,spleen and kidney can guide the treatment of cubital tunnel syndrome with traditional Chinese medicine and acupuncture.By discussing the traditional Chinese medicine(TCM)pathogenesis and treatment principles of cubital tunnel syndrome,it provides modern medical theoretical support for TCM treatment of cubital tunnel syndrome.展开更多
Objective:To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms fo...Objective:To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms for delaying aging, so as to provide experimental basis for acupuncture, moxibustion and Chinese herbs for delaying aging. Methods: Aging mouse model was established by subcutaneous injection of D-galactose, and treated by auricular acupuncture, auricular acupuncture plus moxibustion, and auricular acupuncture plus Chinese herbs respectively for 6 weeks and then serum interleukin-2 (IL-2) and IL-6 contents and splenic lymphocyte transformation rate were compared among the groups. Results: Compared with the young group, the serum IL-2 level and the splenic lymphocyte transformation rate significantly decreased and the IL-6 level significantly increased in the aging mouse. After treatment by auricular acupuncture, auricular acupuncture plus Chinese herbs, especially auricular acupuncture plus moxibustion, the serum IL-2 level and the splenic lymphocyte transformation rate significantly increased, and the IL-6 level significantly decreased as compared with the model group. Conclusions: Combined application of auricular acupuncture, moxibustion and Chinese herbs can improve the decline or dysfunction of immunological function in the aging organism to a certain extent.展开更多
目的:分析脾气虚与现代慢性疾病的相关性,并对常用补气健脾的中药材、食材、药对及经典药膳方进行综述,以期为相关功能性产品开发提供科学依据。方法:以脾气虚、补气健脾、代谢障碍、药膳等为检索词在古籍以及中国知网、万方数据库、维...目的:分析脾气虚与现代慢性疾病的相关性,并对常用补气健脾的中药材、食材、药对及经典药膳方进行综述,以期为相关功能性产品开发提供科学依据。方法:以脾气虚、补气健脾、代谢障碍、药膳等为检索词在古籍以及中国知网、万方数据库、维普数据库、PubMed和Web of Science等数据库查找相关文献进行归纳整理。结果:脾胃气虚证的药理作用研究逐渐深入,补气健脾药物成分研究也达到一定程度,但是对于药食同源食物类的研究较少。结论:应加大对药食同源补气健脾产品的研究。展开更多
目的探究功能性消化不良的中医辨证分型及用药规律,为该病的中医治疗提供参考。方法检索中国知网(CNKI)、万方数据库(Wangfang)、维普数据库(VIP)、PubMed、Web of Science数据库中有关中医药治疗功能性消化不良的临床研究文献,收集中...目的探究功能性消化不良的中医辨证分型及用药规律,为该病的中医治疗提供参考。方法检索中国知网(CNKI)、万方数据库(Wangfang)、维普数据库(VIP)、PubMed、Web of Science数据库中有关中医药治疗功能性消化不良的临床研究文献,收集中药复方,建立数据库,使用Excel 2019、Clementine 12.0和SPSS 21.0对功能性消化不良的中医证型、中药使用频次、功效分类、性味归经进行频次统计,并对高频药物进行关联规则分析、因子分析和聚类分析。结果共纳入文献428篇,提取处方442首,涉及中药225味,高频药物24味,其中党参、茯苓、陈皮、柴胡的使用频次最多,功效分类以补虚药、理气药最为常见,药性以温为主,药味以苦、辛、甘为主,多归脾、肺、胃经;关联规则分析得到20种药物组合,因子分析提取了9个公因子,聚类分析可将药物分为4类。功能性消化不良肝胃不和证最多,对其进行关联规则分析得到12种药物组合,因子分析提取了3个公因子,聚类分析可将药物分为2类。结论中医临床治疗功能性消化不良以益气健脾、疏肝行气药为主,甘温补虚、辛开苦降,辨证配伍化湿、解表、清热等药物。展开更多
目的:探讨补气健脾化痰法对2型糖尿病患者中医证候积分与血管内皮功能的影响。方法:将2019年9月-2021年9月北京中医药大学房山医院月华分院收治的148例2型糖尿病患者随机分成对照组和观察组,对照组74例给予二甲双胍+格列美脲治疗,观察...目的:探讨补气健脾化痰法对2型糖尿病患者中医证候积分与血管内皮功能的影响。方法:将2019年9月-2021年9月北京中医药大学房山医院月华分院收治的148例2型糖尿病患者随机分成对照组和观察组,对照组74例给予二甲双胍+格列美脲治疗,观察组74例给予二甲双胍+格列美脲+补气健脾化痰法治疗,两组均治疗3个月。观察两组的中医证候积分、血糖水平[空腹血糖(Glucose,GLU)、餐后2 h血糖(2 h Postprandial Blood Glucose,2 h PBG)、糖化血红蛋白(Glycosylated Hemoglobin,HbA1c)]、血管内皮功能指标[内皮素-1(Endothelin-1,ET-1)、一氧化氮(Nitric Oxide,NO)、血管性假血友病因子(von Willebrand Factor,vWF)、血栓调节蛋白(Thrombomodulin,TM)]、临床疗效以及不良反应(恶心、呕吐、头晕、嗜睡)。结果:两组治疗后的口渴喜饮、气短寡言、少食易饥、疲乏无力的评分均降低(P<0.05),且观察组治疗后口渴喜饮、气短寡言、少食易饥、疲乏无力的评分低于对照组(P<0.05);两组治疗后的GLU、2 h PBG、HbA1c均降低(P<0.05),且观察组治疗后的GLU、2 h PBG、HbA1c低于对照组(P<0.05);两组治疗后的ET-1、vWF、TM均降低(P<0.05),NO均升高(P<0.05),且观察组治疗后的ET-1、vWF、TM低于对照组(P<0.05),NO高于对照组(P<0.05);观察组总有效率为95.95%(71/74),高于对照组的81.08%(60/74)(P<0.05);观察组不良反应发生率为9.46%(7/74),与对照组的10.81%(8/74)相近(P>0.05)。结论:补气健脾化痰法对2型糖尿病患者的治疗效果较好,可降低中医证候积分,减轻患者症状,且能改善血糖水平与血管内皮功能指标,总有效率高,不良反应少,有效性与安全性兼备,可推广。展开更多
基金Inheritance and innovation of traditional Chinese Medicine"Ten million"talent project(Qihuang project)(No.2019-QTL-003)。
文摘Objective:To systematically evaluate the efficacy and safety of traditional Chinese medicine for regulating spleen and kidney.Methods:We developed a search strategy and then retrieved the database including CNKI,Wanfang data knowledge service platform,VIP journals resource integration service platform,PubMed,Embasefor randomized controlled trial of regulating spleen and kidney traditional Chinese medicine compared with conventional western medicine in the treatment of chronic uric acid nephropathy.The search deadline was set to June 30,2020.For the included literature,we applied the cochrane collaboration network risk bias assessment tool to evaluate the methodological quality,and evaluated the level of evidence according to GRADE standards.Quantitative data was analyzed by RevMan5.3 software,and trial sequential analysis method was used to analyze its efficiency.Results:A total of 709 cases in 10 articles were included.Compared with the control group,the related traditional Chinese medicine group improved the effective rate[RR=1.45,95%CI(1.32,1.58)],reduced the level of UA[MD=-36.24,95%CI(-41.03,-31.45)],BUN[SMD=-1.27,95%CI(-1.47,-1.07)]and SCR[MD=-36.33,95%CI(-55.79,-16.87),P=0.0003],the difference between the two groups was statistically significant(P<0.05).There was no evidence that a significant adverse reaction occurred.The results of TSA analysis showed that the Chinese medicine group had definite evidence for improving the efficiency.According to the GRADE evaluation criteria,the efficiency,UA,BUN and SCR outcome indicators were extremely low-quality evidence.Conclusions:Traditional Chinese medicine for regulating spleen and kidney in the treatment of chronic uric acid nephropathy improved efficiency,reduced the level of UA,BUN,SCR.Meanwhile,the therapy was proved to be safe.Nevertheless,the conclusions need further high-quality evidence to support.
文摘The method of warming the kidney and strengthening the spleen is widely used in the treatment of ulcerative colitis (UC) with significant curative effect.This paper reviews the relevant literature in recent years.
基金TCM science and Technology project of Hebei Provincial Administration of Traditional Chinese Medicine in 2021(No.2021352):The therapeutic effect of cubital tunnel expansion plasty combined with Huangqi Guizhi Wuwu Decoction on cubital tunnel syndrome。
文摘Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second highest among peripheral nerve entrapment diseases,and it is one of the common clinical diseases.The theory of liver,spleen and kidney can guide the treatment of cubital tunnel syndrome with traditional Chinese medicine and acupuncture.By discussing the traditional Chinese medicine(TCM)pathogenesis and treatment principles of cubital tunnel syndrome,it provides modern medical theoretical support for TCM treatment of cubital tunnel syndrome.
文摘Objective:To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms for delaying aging, so as to provide experimental basis for acupuncture, moxibustion and Chinese herbs for delaying aging. Methods: Aging mouse model was established by subcutaneous injection of D-galactose, and treated by auricular acupuncture, auricular acupuncture plus moxibustion, and auricular acupuncture plus Chinese herbs respectively for 6 weeks and then serum interleukin-2 (IL-2) and IL-6 contents and splenic lymphocyte transformation rate were compared among the groups. Results: Compared with the young group, the serum IL-2 level and the splenic lymphocyte transformation rate significantly decreased and the IL-6 level significantly increased in the aging mouse. After treatment by auricular acupuncture, auricular acupuncture plus Chinese herbs, especially auricular acupuncture plus moxibustion, the serum IL-2 level and the splenic lymphocyte transformation rate significantly increased, and the IL-6 level significantly decreased as compared with the model group. Conclusions: Combined application of auricular acupuncture, moxibustion and Chinese herbs can improve the decline or dysfunction of immunological function in the aging organism to a certain extent.
文摘目的:分析脾气虚与现代慢性疾病的相关性,并对常用补气健脾的中药材、食材、药对及经典药膳方进行综述,以期为相关功能性产品开发提供科学依据。方法:以脾气虚、补气健脾、代谢障碍、药膳等为检索词在古籍以及中国知网、万方数据库、维普数据库、PubMed和Web of Science等数据库查找相关文献进行归纳整理。结果:脾胃气虚证的药理作用研究逐渐深入,补气健脾药物成分研究也达到一定程度,但是对于药食同源食物类的研究较少。结论:应加大对药食同源补气健脾产品的研究。
文摘目的:探讨补气健脾化痰法对2型糖尿病患者中医证候积分与血管内皮功能的影响。方法:将2019年9月-2021年9月北京中医药大学房山医院月华分院收治的148例2型糖尿病患者随机分成对照组和观察组,对照组74例给予二甲双胍+格列美脲治疗,观察组74例给予二甲双胍+格列美脲+补气健脾化痰法治疗,两组均治疗3个月。观察两组的中医证候积分、血糖水平[空腹血糖(Glucose,GLU)、餐后2 h血糖(2 h Postprandial Blood Glucose,2 h PBG)、糖化血红蛋白(Glycosylated Hemoglobin,HbA1c)]、血管内皮功能指标[内皮素-1(Endothelin-1,ET-1)、一氧化氮(Nitric Oxide,NO)、血管性假血友病因子(von Willebrand Factor,vWF)、血栓调节蛋白(Thrombomodulin,TM)]、临床疗效以及不良反应(恶心、呕吐、头晕、嗜睡)。结果:两组治疗后的口渴喜饮、气短寡言、少食易饥、疲乏无力的评分均降低(P<0.05),且观察组治疗后口渴喜饮、气短寡言、少食易饥、疲乏无力的评分低于对照组(P<0.05);两组治疗后的GLU、2 h PBG、HbA1c均降低(P<0.05),且观察组治疗后的GLU、2 h PBG、HbA1c低于对照组(P<0.05);两组治疗后的ET-1、vWF、TM均降低(P<0.05),NO均升高(P<0.05),且观察组治疗后的ET-1、vWF、TM低于对照组(P<0.05),NO高于对照组(P<0.05);观察组总有效率为95.95%(71/74),高于对照组的81.08%(60/74)(P<0.05);观察组不良反应发生率为9.46%(7/74),与对照组的10.81%(8/74)相近(P>0.05)。结论:补气健脾化痰法对2型糖尿病患者的治疗效果较好,可降低中医证候积分,减轻患者症状,且能改善血糖水平与血管内皮功能指标,总有效率高,不良反应少,有效性与安全性兼备,可推广。
