Synthesizing a stable and efficient photocatalyst has been the most important research goal up to now. Owing to the dominant performance of g-C3N4 (graphitized carbonitride), an ordered assemble of a composite photoca...Synthesizing a stable and efficient photocatalyst has been the most important research goal up to now. Owing to the dominant performance of g-C3N4 (graphitized carbonitride), an ordered assemble of a composite photocatalyst, Zn-Ni-P@g-C3N4, was successfully designed and controllably prepared for highly efficient photocatalytic H2 evolution. The electron transport routes were successfully adjusted and the H2 evolution was greatly improved. The maximum amount of H2 evolved reached about 531.2 μmol for 5 h over Zn-Ni-P@g-C3N4 photocatalyst with a molar ratio of Zn to Ni of 1:3 under illumination of 5 W LED white light (wavelength 420 nm). The H2 evolution rate was 54.7 times higher than that over pure g-C3N4. Moreover, no obvious reduction in the photocatalytic activity was observed even after 4 cycles of H2 production for 5 h. This synergistically increased effect was confirmed through the results of characterizations such as XRD, TEM, SEM, XPS, N2 adsorption, UV-vis DRS, transient photocurrent, FT-IR, transient fluorescence, and Mott-Schottky studies. These studies showed that the Zn-Ni-P nanoparticles modified on g-C3N4 provide more active sites and improve the efficiency of photogenerated charge separation. In addition, the possible mechanism of photocatalytic H2 production is proposed.展开更多
Real-time monitoring of the 14-MeV D-T fusion neutron yield is urgently required for the triton burnup study on the Experimental Advanced Superconducting Tokamak (EAST). In this study, we developed an optimal design o...Real-time monitoring of the 14-MeV D-T fusion neutron yield is urgently required for the triton burnup study on the Experimental Advanced Superconducting Tokamak (EAST). In this study, we developed an optimal design of a fast-neutron detector based on the scintillating fiber (Sci-Fi) to provide D-T neutron yield through Geant4simulation. The effect on the detection performance is concerned when changing the number of the Sci-Fis embedded in the probe head, minimum distance between the fibers, length of the fibers, or substrate material of the probe head. The maximum number of scintillation photons generated by the n/γ source particles and output by the light guide within an event (event:the entire simulation process for one source particle) was used to quantify the n/γ resolution of the detector as the main basis. And the intrinsic detection efficiency was used as another evaluation criterion. The results demonstrate that the optimal design scheme is to use a 5 cm probe head whose substrate material is pure aluminum, in which 463 Sci-Fis with the same length of 5 cm are embedded, and the minimum distance between the centers of the two fibers is 2 mm. The optimized detector exhibits clear directionality in the simulation, which is in line with the expectation and experimental data provided in the literature. This study presents the variation trends of the performance of the SciFi detector when its main parameters change, which is beneficial for the targeted design and optimization of the Sci-Fi detector used in a specific radiation environment.展开更多
Presents the new concept of ″Desired to be small″ based on the basic function of vehicle flight control system for an optimal design of flying vehicle control system, and the definition of S/N ratio and calculation ...Presents the new concept of ″Desired to be small″ based on the basic function of vehicle flight control system for an optimal design of flying vehicle control system, and the definition of S/N ratio and calculation formula for ″Desired to be small″ dynamic characteristics, and the S/N ratio method established for design of velicle flight control systems, by which, an orthogrnal table is used to arrange test schemes, and error facters are used to simulate various interferences, and the use of S/N ratio as a design criterion to synthesise the design of dynamic and static characteristics for definition of an optimal scheme, the application of S/N ratio method to the design of a type of vehicle control system and the single run success abtained in design of control system, technical evaluation test and design finalization flight test.展开更多
The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed...The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed on g PROMS platform to get easy access to the solutions of reactive extraction with phase splitting. Based on rigorous criteria, dynamic analysis from initial state to final equilibrium(e.g., evolution of phase composition, mass transfer rate and reaction rate) and optimal design of operating conditions(e.g., extractant dosage and feed molar ratio) are achieved. To illustrate the method, the esterification of n-hexyl acetate is taken as an example. The approach proves to be reliable in the analysis and optimization of the exemplified system, which provides instructive reference for further process design and simulation of reactive extraction.展开更多
A t-(v,k,λ)design(X,B)is a set X of points,of cardinality v,and a collection B of k-subsets of X called blocks,with the property that every t-subset of X is contained in precisely λ blocks.A t-design is a t-(v,k,λ)...A t-(v,k,λ)design(X,B)is a set X of points,of cardinality v,and a collection B of k-subsets of X called blocks,with the property that every t-subset of X is contained in precisely λ blocks.A t-design is a t-(v,k,λ) design for some v,k,γ.In this paper,we give a generalization of t-design called balanced n-ary t-design,and obtain some properties of the new combinatorial structure.展开更多
Concepts for a virtual 3D space and a hyper-sphere are proposed and the formulae for determining the computable nodes of the mesh are derived.Then a new optimization design method('Virtual Mesh Method'or V.M.M...Concepts for a virtual 3D space and a hyper-sphere are proposed and the formulae for determining the computable nodes of the mesh are derived.Then a new optimization design method('Virtual Mesh Method'or V.M.M)is developed.Three examples are given,showing that the method proposed is especially suitable for the optimized design of complex structures,and that the global approximate optimal solution can be searched with remarkably reduced computational work.展开更多
Soil samples were taken from depth of 0-12 cm in virgin broad-leaved Korean pine mixed forest in Changbai Moun-tain in July 2000. The effects of temperature, soil water content, pH, NH4+ and NO3- on N2O emission and C...Soil samples were taken from depth of 0-12 cm in virgin broad-leaved Korean pine mixed forest in Changbai Moun-tain in July 2000. The effects of temperature, soil water content, pH, NH4+ and NO3- on N2O emission and CH4 uptake of a for-est soil were studied in laboratory by the method of orthogonal design. It was observed under laboratory conditions in this study that there were significant correlations between N2O emission rate, CH4 oxidation rate, soil pH and temperature. Nevertheless, N2O emission rate also showed a significant positive correlation with CH4 oxidation rate. The results suggested that pH and temperature were important factors controlling N2O emission and CH4 oxidation under this experiment conditions.展开更多
Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA vaccines.However,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation ef...Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA vaccines.However,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation efficiency of the 5'UTR.We discovered that the optimal 5'UTR for m1y-modified mRNA(m1y-5'UTR)differs significantly from its unmodified counterpart,high-lighting the need for a specialized tool for designing mly-5'UTRs rather than directly utilizing high-expression endogenous gene 5'UTRs.In response,we developed a novel machine learning-based tool,Smart5UTR,which employs a deep generative model to identify superior m1y-5'UTRs in silico.The tailored loss function and network architecture enable Smart5UTR to overcome limitations inherent in existing models.As a result,Smart5UTR can successfully design superior 5'UTRs,greatly benefiting mRNA vaccine development.Notably,Smart5UTR-designed superior 5'UTRs significantly enhanced antibody titers induced by COVID-19 mRNA vaccines against the Delta and Omicron variants of SARS-CoV-2,surpassing the performance of vaccines using high-expression endogenous gene 5'UTRs.展开更多
基金supported by the National Natural Science Foundation of China(21862002,41663012)the Innovation Team Project of North Minzu University(YCX18082)the Scientific Research Project of North Minzu University(2016 HG-KY 06)~~
文摘Synthesizing a stable and efficient photocatalyst has been the most important research goal up to now. Owing to the dominant performance of g-C3N4 (graphitized carbonitride), an ordered assemble of a composite photocatalyst, Zn-Ni-P@g-C3N4, was successfully designed and controllably prepared for highly efficient photocatalytic H2 evolution. The electron transport routes were successfully adjusted and the H2 evolution was greatly improved. The maximum amount of H2 evolved reached about 531.2 μmol for 5 h over Zn-Ni-P@g-C3N4 photocatalyst with a molar ratio of Zn to Ni of 1:3 under illumination of 5 W LED white light (wavelength 420 nm). The H2 evolution rate was 54.7 times higher than that over pure g-C3N4. Moreover, no obvious reduction in the photocatalytic activity was observed even after 4 cycles of H2 production for 5 h. This synergistically increased effect was confirmed through the results of characterizations such as XRD, TEM, SEM, XPS, N2 adsorption, UV-vis DRS, transient photocurrent, FT-IR, transient fluorescence, and Mott-Schottky studies. These studies showed that the Zn-Ni-P nanoparticles modified on g-C3N4 provide more active sites and improve the efficiency of photogenerated charge separation. In addition, the possible mechanism of photocatalytic H2 production is proposed.
基金supported by the Users with Excellence Program of Hefei Science Center CAS(No.2020HSC-UE012)the Comprehensive Research Facility for Fusion Technology Program of China(No.2018-000052-73-01-001228)the Institute of Energy,Hefei Comprehensive National Science Center(No.21KZS205,21KZL401).
文摘Real-time monitoring of the 14-MeV D-T fusion neutron yield is urgently required for the triton burnup study on the Experimental Advanced Superconducting Tokamak (EAST). In this study, we developed an optimal design of a fast-neutron detector based on the scintillating fiber (Sci-Fi) to provide D-T neutron yield through Geant4simulation. The effect on the detection performance is concerned when changing the number of the Sci-Fis embedded in the probe head, minimum distance between the fibers, length of the fibers, or substrate material of the probe head. The maximum number of scintillation photons generated by the n/γ source particles and output by the light guide within an event (event:the entire simulation process for one source particle) was used to quantify the n/γ resolution of the detector as the main basis. And the intrinsic detection efficiency was used as another evaluation criterion. The results demonstrate that the optimal design scheme is to use a 5 cm probe head whose substrate material is pure aluminum, in which 463 Sci-Fis with the same length of 5 cm are embedded, and the minimum distance between the centers of the two fibers is 2 mm. The optimized detector exhibits clear directionality in the simulation, which is in line with the expectation and experimental data provided in the literature. This study presents the variation trends of the performance of the SciFi detector when its main parameters change, which is beneficial for the targeted design and optimization of the Sci-Fi detector used in a specific radiation environment.
文摘Presents the new concept of ″Desired to be small″ based on the basic function of vehicle flight control system for an optimal design of flying vehicle control system, and the definition of S/N ratio and calculation formula for ″Desired to be small″ dynamic characteristics, and the S/N ratio method established for design of velicle flight control systems, by which, an orthogrnal table is used to arrange test schemes, and error facters are used to simulate various interferences, and the use of S/N ratio as a design criterion to synthesise the design of dynamic and static characteristics for definition of an optimal scheme, the application of S/N ratio method to the design of a type of vehicle control system and the single run success abtained in design of control system, technical evaluation test and design finalization flight test.
基金Supported by the National Natural Science Foundation of China(21776074,21576081,2181101120).
文摘The dynamic analysis and optimal design of reactive extraction are challenging due to high nonlinearity of model equations and tough decision of judging criteria. In this work, a dynamic rate-based method is developed on g PROMS platform to get easy access to the solutions of reactive extraction with phase splitting. Based on rigorous criteria, dynamic analysis from initial state to final equilibrium(e.g., evolution of phase composition, mass transfer rate and reaction rate) and optimal design of operating conditions(e.g., extractant dosage and feed molar ratio) are achieved. To illustrate the method, the esterification of n-hexyl acetate is taken as an example. The approach proves to be reliable in the analysis and optimization of the exemplified system, which provides instructive reference for further process design and simulation of reactive extraction.
文摘A t-(v,k,λ)design(X,B)is a set X of points,of cardinality v,and a collection B of k-subsets of X called blocks,with the property that every t-subset of X is contained in precisely λ blocks.A t-design is a t-(v,k,λ) design for some v,k,γ.In this paper,we give a generalization of t-design called balanced n-ary t-design,and obtain some properties of the new combinatorial structure.
基金Project supported by the Natural Science Foundation of Henan Province,China(No.0311010400).
文摘Concepts for a virtual 3D space and a hyper-sphere are proposed and the formulae for determining the computable nodes of the mesh are derived.Then a new optimization design method('Virtual Mesh Method'or V.M.M)is developed.Three examples are given,showing that the method proposed is especially suitable for the optimized design of complex structures,and that the global approximate optimal solution can be searched with remarkably reduced computational work.
基金This paper was supported by Chinese Academy of Sciences.
文摘Soil samples were taken from depth of 0-12 cm in virgin broad-leaved Korean pine mixed forest in Changbai Moun-tain in July 2000. The effects of temperature, soil water content, pH, NH4+ and NO3- on N2O emission and CH4 uptake of a for-est soil were studied in laboratory by the method of orthogonal design. It was observed under laboratory conditions in this study that there were significant correlations between N2O emission rate, CH4 oxidation rate, soil pH and temperature. Nevertheless, N2O emission rate also showed a significant positive correlation with CH4 oxidation rate. The results suggested that pH and temperature were important factors controlling N2O emission and CH4 oxidation under this experiment conditions.
基金This work was financially supported by the Postdoctoral Research Foundation of National Key S&T Special Projects(2018ZX09201018-024,China)Sichuan Province Science and Technology Support Program(2022YFH0001 and 2021YFH0003,China).
文摘Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA vaccines.However,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation efficiency of the 5'UTR.We discovered that the optimal 5'UTR for m1y-modified mRNA(m1y-5'UTR)differs significantly from its unmodified counterpart,high-lighting the need for a specialized tool for designing mly-5'UTRs rather than directly utilizing high-expression endogenous gene 5'UTRs.In response,we developed a novel machine learning-based tool,Smart5UTR,which employs a deep generative model to identify superior m1y-5'UTRs in silico.The tailored loss function and network architecture enable Smart5UTR to overcome limitations inherent in existing models.As a result,Smart5UTR can successfully design superior 5'UTRs,greatly benefiting mRNA vaccine development.Notably,Smart5UTR-designed superior 5'UTRs significantly enhanced antibody titers induced by COVID-19 mRNA vaccines against the Delta and Omicron variants of SARS-CoV-2,surpassing the performance of vaccines using high-expression endogenous gene 5'UTRs.
