BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare primary neoplasms of the gastrointestinal tract,accounting for 1%to 2%of all gastrointestinal neoplasms worldwide.GISTs are frequently discovered incidentally ...BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare primary neoplasms of the gastrointestinal tract,accounting for 1%to 2%of all gastrointestinal neoplasms worldwide.GISTs are frequently discovered incidentally during workup for other diagnosis or intestinal obstruction,as they can present with few or no symptoms.Simultaneously,GISTs confer a high degree of malignant transformation,with a progression in about 10%to 30%of cases.CASE SUMMARY A 63-year-old healthy female presented to our institution with complaints of right knee pain and limited passive and active motion in the setting of a previous right total knee arthroplasty(TKA).One year after TKA,the patient was incidentally diagnosed with a GIST,which was successfully removed.After removal,the patient continued to have limited range of motion of the right knee and subsequently underwent revision TKA.Intraoperatively significant fibrotic adhesions were found encapsulating the femoral and tibial components.The patient’s pain improved postoperatively,however,she continued to have decreased range of motion with difficulty ambulating.CONCLUSION We propose that this case may demonstrate a proinflammatory milieu arising from a GIST,which had a direct influence on the outcome of recent total knee arthroplasty.This proposed mechanism between neoplastic cytokinetic activity and adhesion formation could have implications on preoperative and postoperative orthopedic management of total knee arthroplasty.展开更多
Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the probl...Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the problem of the lack of consideration of adhesion difference of train wheelsets in the existing high-speed train electric-air braking force optimal allocation strategies.In this method,the braking strategy gives priority to the use of electric braking force.The force model of a single train in the braking process is analyzed to calculate the change of adhesion between the wheel and rail of each wheelset after axle load transfer,and then the adhesion of the train is estimated in real time.Next,with the goal of maximizing the total adhesion utilization ratio of trailer/motor vehicles,a linear programming distribution function is constructed.The proportional coefficient of adhesion utilization ratio of each train and the application upper limit of braking force in the function is updated according to the change time point of wheelset adhesion.Finally,the braking force is dynamically allocated.The simulation results of Matlab/Simulink show that the proposed algorithm not only uses the different adhesion limits of each trailer to reduce the total amount of braking force undertaken by the motor vehicle,but also considers the adhesion difference of each wheelset.The strategy can effectively reduce the risk and time of motor vehicles during the braking process and improve the stability of the train braking.展开更多
目的:通过微拉伸粘结强度检测法,比较3种不同的牙本质粘结剂Single Bond 2、SE Bond和Easy One的粘结强度,为临床应用提供参考。方法:选用30个新鲜拔除的人磨牙,磨除牙合面釉质暴露牙本质,随机分为3组,每组10个牙,分别使用Single Bond 2...目的:通过微拉伸粘结强度检测法,比较3种不同的牙本质粘结剂Single Bond 2、SE Bond和Easy One的粘结强度,为临床应用提供参考。方法:选用30个新鲜拔除的人磨牙,磨除牙合面釉质暴露牙本质,随机分为3组,每组10个牙,分别使用Single Bond 2、SE Bond、Easy One粘结剂,再用蓝色复合树脂充填5 mm高度。在流水下,用慢速锯垂直于粘结面制备成1.0 mm×1.0 mm横截面积的柱状试件,用微拉伸测试仪测试其微拉伸强度,用体视显微镜观察样本断裂类型,对微拉伸强度测试值和断裂类型进行统计学分析。结果:Single Bond 2组的微拉伸强度为(23.40±6.20)MPa,Easy One组为(16.25±4.42)MPa,SE Bond组(16.17±4.78)MPa。经方差分析,Single Bond 2组与另两组粘结剂微拉伸强度均有显著性差异(P<0.05),而SE Bond组和Easy One组无显著性差异(P>0.05)。结论:Single Bond 2粘结强度优于Easy One、SE Bond,3种粘结剂的粘结强度均可满足临床应用要求。展开更多
文摘BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare primary neoplasms of the gastrointestinal tract,accounting for 1%to 2%of all gastrointestinal neoplasms worldwide.GISTs are frequently discovered incidentally during workup for other diagnosis or intestinal obstruction,as they can present with few or no symptoms.Simultaneously,GISTs confer a high degree of malignant transformation,with a progression in about 10%to 30%of cases.CASE SUMMARY A 63-year-old healthy female presented to our institution with complaints of right knee pain and limited passive and active motion in the setting of a previous right total knee arthroplasty(TKA).One year after TKA,the patient was incidentally diagnosed with a GIST,which was successfully removed.After removal,the patient continued to have limited range of motion of the right knee and subsequently underwent revision TKA.Intraoperatively significant fibrotic adhesions were found encapsulating the femoral and tibial components.The patient’s pain improved postoperatively,however,she continued to have decreased range of motion with difficulty ambulating.CONCLUSION We propose that this case may demonstrate a proinflammatory milieu arising from a GIST,which had a direct influence on the outcome of recent total knee arthroplasty.This proposed mechanism between neoplastic cytokinetic activity and adhesion formation could have implications on preoperative and postoperative orthopedic management of total knee arthroplasty.
基金supported by the National Natural Science Foundation of China(Grant Nos.62173137,52172403,62303178).
文摘Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the problem of the lack of consideration of adhesion difference of train wheelsets in the existing high-speed train electric-air braking force optimal allocation strategies.In this method,the braking strategy gives priority to the use of electric braking force.The force model of a single train in the braking process is analyzed to calculate the change of adhesion between the wheel and rail of each wheelset after axle load transfer,and then the adhesion of the train is estimated in real time.Next,with the goal of maximizing the total adhesion utilization ratio of trailer/motor vehicles,a linear programming distribution function is constructed.The proportional coefficient of adhesion utilization ratio of each train and the application upper limit of braking force in the function is updated according to the change time point of wheelset adhesion.Finally,the braking force is dynamically allocated.The simulation results of Matlab/Simulink show that the proposed algorithm not only uses the different adhesion limits of each trailer to reduce the total amount of braking force undertaken by the motor vehicle,but also considers the adhesion difference of each wheelset.The strategy can effectively reduce the risk and time of motor vehicles during the braking process and improve the stability of the train braking.
文摘目的:通过微拉伸粘结强度检测法,比较3种不同的牙本质粘结剂Single Bond 2、SE Bond和Easy One的粘结强度,为临床应用提供参考。方法:选用30个新鲜拔除的人磨牙,磨除牙合面釉质暴露牙本质,随机分为3组,每组10个牙,分别使用Single Bond 2、SE Bond、Easy One粘结剂,再用蓝色复合树脂充填5 mm高度。在流水下,用慢速锯垂直于粘结面制备成1.0 mm×1.0 mm横截面积的柱状试件,用微拉伸测试仪测试其微拉伸强度,用体视显微镜观察样本断裂类型,对微拉伸强度测试值和断裂类型进行统计学分析。结果:Single Bond 2组的微拉伸强度为(23.40±6.20)MPa,Easy One组为(16.25±4.42)MPa,SE Bond组(16.17±4.78)MPa。经方差分析,Single Bond 2组与另两组粘结剂微拉伸强度均有显著性差异(P<0.05),而SE Bond组和Easy One组无显著性差异(P>0.05)。结论:Single Bond 2粘结强度优于Easy One、SE Bond,3种粘结剂的粘结强度均可满足临床应用要求。
