In this study, PCR-RFLP technique was employed to detect the genetic polymorphism of NPY gene and analyze the effects of various genotypes on the total number of eggs at 300 days of age in 135 Donglan black-bone chick...In this study, PCR-RFLP technique was employed to detect the genetic polymorphism of NPY gene and analyze the effects of various genotypes on the total number of eggs at 300 days of age in 135 Donglan black-bone chicken. According to the results, there were three genotypes （AA, AB and BB） of NPYgene in Donglan black-bone chicken group. Different genotypes exhibited significant effects （P 〈 0. 05 ） on the total number of eggs at 300 days of age. The total number of eggs at 300 days of age of AA genotype was significantly higher than that of BB genotype （P 〈 0. 05）. Therefore, the polymorphic site of NPY gene could be used as a candidate molecular marker that affects egg laying in Donglan black-bone chicken.展开更多
Background:Pancreatic signet ring cell carcinoma(SRCC)is an exceedingly rare histological subtype of pancreatic cancer.Previous studies have focused on the trends of incidence and independent predictors of pancreatic ...Background:Pancreatic signet ring cell carcinoma(SRCC)is an exceedingly rare histological subtype of pancreatic cancer.Previous studies have focused on the trends of incidence and independent predictors of pancreatic SRCC.Our objectives of the study were to analyze the prognostic value of the lymph node ratio(LNR)and to explore the minimal number of lymph nodes examined to accurately evaluate the N stage in resected pancreatic SRCC.Method:We analyzed 120 patients diagnosed from January 1,1990,to December 31,2016,constituted the study cohort from the Surveillance,Epidemiology,and End Results(SEER)registry.We calculated the overall survival(OS)of these patients by using a Kaplan–Meier analysis.The Kaplan–Meier analysis was used to analyze the influence of various factors on the prognosis of patients in the univariate analysis.The multivariate Cox analysis were applied to find independent prognostic factors of patients with pancreatic SRCC.Receiver-operating characteristic curve(ROC)analysis to investigate the discriminatory ability of the total number of lymph nodes examined(TNLE)relative to whether lymph node metastasis was present.Results:The median number of lymph nodes examined among 120 patients with resected pancreatic SRCC was 14(interquartile range:6.25–20.0).According to the univariate analysis of OS,age,grade,chemotherapy,LNR,and TNLE were significantly different(P<.05).We demonstrated the prognostic benefit of chemotherapy in resected pancreatic SRCC,whereas radiotherapy was not associated with improved survival.The multivariate survival analysis showed that LNR and grade were independent prognostic indicators after pancreatic SRCC resection for OS.TNLE≥8 showed the highest discriminatory power for evaluating lymph node metastasis(Area under curve(AUC):0.656,95%confidence interval:0.564–0.741,Youden index:0.2533,sensitivity:78.67%,specificity:46.67%,P=.003).Conclusion:Our study indicated that the LNR was a valuable independent prognostic factor for resected pancreatic SRCC.Regional lymphadenectomy of at least 8 lymph nodes was necessary to accurately stage patients.An adequate number of lymph nodes examined are necessary for clinicians to accurately predict the significance of the LNR in resected pancreatic SRCC.展开更多
Let G = （V, E） be a graph, and let f ： V →{-1, 1} be a two-valued function. If ∑x∈N（v） f（x） ≥ 1 for each v ∈ V, where N（v） is the open neighborhood of v, then f is a signed total dominating function on ...Let G = （V, E） be a graph, and let f ： V →{-1, 1} be a two-valued function. If ∑x∈N（v） f（x） ≥ 1 for each v ∈ V, where N（v） is the open neighborhood of v, then f is a signed total dominating function on G. A set {fl, f2,… fd} of signed d total dominating functions on G with the property that ∑i=1^d fi（x） ≤ 1 for each x ∈ V, is called a signed total dominating family （of functions） on G. The maximum number of functions in a signed total dominating family on G is the signed total domatic number on G, denoted by dt^s（G）. The properties of the signed total domatic number dt^s（G） are studied in this paper. In particular, we give the sharp bounds of the signed total domatic number of regular graphs, complete bipartite graphs and complete graphs.展开更多
图 G 的全部的色彩的数字 T (G) 是需要渲染 G 的元素(顶点和边) 的颜色的最小的数字以便不邻近或元素的事件对收到一样的颜色。G 被称为类型 1 如果 T (G)=(G)+ 1。在这份报纸，我们证明完全的由两部组成的图 Km， n 和周期 Cn 的 join...图 G 的全部的色彩的数字 T (G) 是需要渲染 G 的元素(顶点和边) 的颜色的最小的数字以便不邻近或元素的事件对收到一样的颜色。G 被称为类型 1 如果 T (G)=(G)+ 1。在这份报纸，我们证明完全的由两部组成的图 Km， n 和周期 Cn 的 join 具有类型 1。展开更多
A proper total-coloring of graph G is said to be?equitable if the number of elements (vertices and edges) in any?two color classes differ by at most one, which the required?minimum number of colors is called the equit...A proper total-coloring of graph G is said to be?equitable if the number of elements (vertices and edges) in any?two color classes differ by at most one, which the required?minimum number of colors is called the equitable total chromatic?number. In this paper, we prove some theorems on equitable?total coloring and derive the equitable total chromatic numbers?of Pm V?Sn, Pm V?Fn and Pm V Wn.展开更多
This paper discusses the total irredundance relations between the graph G and its clone-contraction graph H, that is, let H be the clone-contraction graph of G and v1,v2,...,vk be all contraction vertices ofH. IfS is ...This paper discusses the total irredundance relations between the graph G and its clone-contraction graph H, that is, let H be the clone-contraction graph of G and v1,v2,...,vk be all contraction vertices ofH. IfS is a maximal total irredundant set of H such that A = S ∩ {V1,V2,…,Vk} contains as few vertices as possible, then S＇= S-A is the maximal total irredundant set of G. Furthermore, we obtain the bound of the total irredundance A（G） number： irt ≤△（G）/2△（G）＋1 n, which n is the order of graph G, and △（G） is maximum degree in G.展开更多
Generalized Petersen graphs are an important class of commonly used interconnection networks and have been studied . The total domination number of generalized Petersen graphs P(m,2) is obtained in this paper.
本研究旨在挖掘影响蕨麻猪总产仔数(Total number born,TNB)和产活仔数(Number born alive,NBA)的候选基因,为蕨麻猪高繁殖力基因组选育提供参考数据。采集140头蕨麻猪耳组织样品,提取DNA,利用50K液相芯片进行SNPs检测。分别采用广义线...本研究旨在挖掘影响蕨麻猪总产仔数(Total number born,TNB)和产活仔数(Number born alive,NBA)的候选基因,为蕨麻猪高繁殖力基因组选育提供参考数据。采集140头蕨麻猪耳组织样品,提取DNA,利用50K液相芯片进行SNPs检测。分别采用广义线性模型和混合线性模型对140头蕨麻猪个体的SNPs与TNB和NBA进行全基因组关联分析(Genome-wide association studies,GWAS),筛选影响该群体繁殖性状的候选基因。结果显示:针对TNB和NBA等2个性状,广义线性模型分别检测到14个和1个显著的SNPs位点。混合线性模型检测到TNB有2个显著的SNPs位点;未检测到显著影响NBA的SNP。筛选ZCCHC24、ENSSSCG00000046125和TENM1作为影响TNB的重要候选基因,ZCCHC24作为影响NBA的重要候选基因。展开更多
In the issue of rainfall estimation by radar through the necessary relationship between radar reflectivity Z and rain rate R (Z-R), the main limitation is attributed to the variability of this relationship. Indeed, se...In the issue of rainfall estimation by radar through the necessary relationship between radar reflectivity Z and rain rate R (Z-R), the main limitation is attributed to the variability of this relationship. Indeed, several pre-vious studies have shown the great variability of this relationship in space and time, from a rainfall event to another and even within a single rainfall event. Recent studies have shown that the variability of raindrop size distributions and thereby Z-R relationships is therefore, more the result of complex dynamic, thermody-namic and microphysical processes within rainfall systems than a convective/stratiform classification of the ground rainfall signature. The raindrop number and size at ground being the resultant of various processes mentioned above, a suitable approach would be to analyze their variability in relation to that of Z-R relation-ship. In this study, we investigated the total raindrop concentration number NT and the median volume di-ameter D0 used in numerous studies, and have shown that the combination of these two ‘observed’ parame-ters appears to be an interesting approach to better understand the variability of the Z-R relationships in the rainfall events, without assuming a certain analytical raindrop size distribution model (exponential, gamma, or log-normal). The present study is based on the analysis of disdrometer data collected at different seasons and places in Africa, and aims to show the degree of the raindrop size and number implication in regard to the Z-R relationships variability.展开更多
基金Supported by Natural Science Foundation of Guangxi Zhuang Autonomous Region(2013jj DA30049)
文摘In this study, PCR-RFLP technique was employed to detect the genetic polymorphism of NPY gene and analyze the effects of various genotypes on the total number of eggs at 300 days of age in 135 Donglan black-bone chicken. According to the results, there were three genotypes （AA, AB and BB） of NPYgene in Donglan black-bone chicken group. Different genotypes exhibited significant effects （P 〈 0. 05 ） on the total number of eggs at 300 days of age. The total number of eggs at 300 days of age of AA genotype was significantly higher than that of BB genotype （P 〈 0. 05）. Therefore, the polymorphic site of NPY gene could be used as a candidate molecular marker that affects egg laying in Donglan black-bone chicken.
文摘Background:Pancreatic signet ring cell carcinoma(SRCC)is an exceedingly rare histological subtype of pancreatic cancer.Previous studies have focused on the trends of incidence and independent predictors of pancreatic SRCC.Our objectives of the study were to analyze the prognostic value of the lymph node ratio(LNR)and to explore the minimal number of lymph nodes examined to accurately evaluate the N stage in resected pancreatic SRCC.Method:We analyzed 120 patients diagnosed from January 1,1990,to December 31,2016,constituted the study cohort from the Surveillance,Epidemiology,and End Results(SEER)registry.We calculated the overall survival(OS)of these patients by using a Kaplan–Meier analysis.The Kaplan–Meier analysis was used to analyze the influence of various factors on the prognosis of patients in the univariate analysis.The multivariate Cox analysis were applied to find independent prognostic factors of patients with pancreatic SRCC.Receiver-operating characteristic curve(ROC)analysis to investigate the discriminatory ability of the total number of lymph nodes examined(TNLE)relative to whether lymph node metastasis was present.Results:The median number of lymph nodes examined among 120 patients with resected pancreatic SRCC was 14(interquartile range:6.25–20.0).According to the univariate analysis of OS,age,grade,chemotherapy,LNR,and TNLE were significantly different(P<.05).We demonstrated the prognostic benefit of chemotherapy in resected pancreatic SRCC,whereas radiotherapy was not associated with improved survival.The multivariate survival analysis showed that LNR and grade were independent prognostic indicators after pancreatic SRCC resection for OS.TNLE≥8 showed the highest discriminatory power for evaluating lymph node metastasis(Area under curve(AUC):0.656,95%confidence interval:0.564–0.741,Youden index:0.2533,sensitivity:78.67%,specificity:46.67%,P=.003).Conclusion:Our study indicated that the LNR was a valuable independent prognostic factor for resected pancreatic SRCC.Regional lymphadenectomy of at least 8 lymph nodes was necessary to accurately stage patients.An adequate number of lymph nodes examined are necessary for clinicians to accurately predict the significance of the LNR in resected pancreatic SRCC.
基金Project supported by the National Natural Science Foundation of China （Grant No.1057117）, and the Science Foundation of Shanghai Municipal Commission of Education （Grant No.05AZ04）.
文摘Let G = （V, E） be a graph, and let f ： V →{-1, 1} be a two-valued function. If ∑x∈N（v） f（x） ≥ 1 for each v ∈ V, where N（v） is the open neighborhood of v, then f is a signed total dominating function on G. A set {fl, f2,… fd} of signed d total dominating functions on G with the property that ∑i=1^d fi（x） ≤ 1 for each x ∈ V, is called a signed total dominating family （of functions） on G. The maximum number of functions in a signed total dominating family on G is the signed total domatic number on G, denoted by dt^s（G）. The properties of the signed total domatic number dt^s（G） are studied in this paper. In particular, we give the sharp bounds of the signed total domatic number of regular graphs, complete bipartite graphs and complete graphs.
文摘A proper total-coloring of graph G is said to be?equitable if the number of elements (vertices and edges) in any?two color classes differ by at most one, which the required?minimum number of colors is called the equitable total chromatic?number. In this paper, we prove some theorems on equitable?total coloring and derive the equitable total chromatic numbers?of Pm V?Sn, Pm V?Fn and Pm V Wn.
基金Supported by the National Natural Science Foundation of China (10571071,10371048)
文摘This paper discusses the total irredundance relations between the graph G and its clone-contraction graph H, that is, let H be the clone-contraction graph of G and v1,v2,...,vk be all contraction vertices ofH. IfS is a maximal total irredundant set of H such that A = S ∩ {V1,V2,…,Vk} contains as few vertices as possible, then S＇= S-A is the maximal total irredundant set of G. Furthermore, we obtain the bound of the total irredundance A（G） number： irt ≤△（G）/2△（G）＋1 n, which n is the order of graph G, and △（G） is maximum degree in G.
文摘Generalized Petersen graphs are an important class of commonly used interconnection networks and have been studied . The total domination number of generalized Petersen graphs P(m,2) is obtained in this paper.
文摘本研究旨在挖掘影响蕨麻猪总产仔数(Total number born,TNB)和产活仔数(Number born alive,NBA)的候选基因,为蕨麻猪高繁殖力基因组选育提供参考数据。采集140头蕨麻猪耳组织样品,提取DNA,利用50K液相芯片进行SNPs检测。分别采用广义线性模型和混合线性模型对140头蕨麻猪个体的SNPs与TNB和NBA进行全基因组关联分析(Genome-wide association studies,GWAS),筛选影响该群体繁殖性状的候选基因。结果显示:针对TNB和NBA等2个性状,广义线性模型分别检测到14个和1个显著的SNPs位点。混合线性模型检测到TNB有2个显著的SNPs位点;未检测到显著影响NBA的SNP。筛选ZCCHC24、ENSSSCG00000046125和TENM1作为影响TNB的重要候选基因,ZCCHC24作为影响NBA的重要候选基因。
文摘In the issue of rainfall estimation by radar through the necessary relationship between radar reflectivity Z and rain rate R (Z-R), the main limitation is attributed to the variability of this relationship. Indeed, several pre-vious studies have shown the great variability of this relationship in space and time, from a rainfall event to another and even within a single rainfall event. Recent studies have shown that the variability of raindrop size distributions and thereby Z-R relationships is therefore, more the result of complex dynamic, thermody-namic and microphysical processes within rainfall systems than a convective/stratiform classification of the ground rainfall signature. The raindrop number and size at ground being the resultant of various processes mentioned above, a suitable approach would be to analyze their variability in relation to that of Z-R relation-ship. In this study, we investigated the total raindrop concentration number NT and the median volume di-ameter D0 used in numerous studies, and have shown that the combination of these two ‘observed’ parame-ters appears to be an interesting approach to better understand the variability of the Z-R relationships in the rainfall events, without assuming a certain analytical raindrop size distribution model (exponential, gamma, or log-normal). The present study is based on the analysis of disdrometer data collected at different seasons and places in Africa, and aims to show the degree of the raindrop size and number implication in regard to the Z-R relationships variability.
