BACKGROUND Tracheal neoplasms represent less than 0.1%of all malignancies and have no established treatment guidelines.Surgical resection with reconstruction is the primary treatment.This study demonstrates successful...BACKGROUND Tracheal neoplasms represent less than 0.1%of all malignancies and have no established treatment guidelines.Surgical resection with reconstruction is the primary treatment.This study demonstrates successful treatment of concurrent lung and tracheal tumors using surgical excision and intraoperative photodynamic therapy(PDT),highlighting the effectiveness and safety of this approach.CASE SUMMARY A 74-year-old male with a history of smoking and chronic obstructive pulmonary disease was diagnosed with tracheal squamous cell carcinoma and right lower lobe adenocarcinoma.A multidisciplinary team created a treatment plan involving tumor resection and PDT.The tracheal tumor was removed through a tracheal incision and this was followed by intraluminal PDT.The trachea was repaired and a right lower lobectomy was performed.The patient received a second PDT treatment postoperatively and was discharged 10 d after the tracheal surgery,without complications.He then underwent platinum-based chemotherapy for lymphovascular invasion of lung cancer.Three-month postoperative bronchoscopy revealed normal tracheal mucosa with a scar at the resection site and no evidence of tumor recurrence in the trachea or lung.CONCLUSION Our case of concurrent tracheal and lung cancers was successfully treated with surgical excision and intraoperative PDT which proved safe and effective in this patient.展开更多
Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and per...Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and pertinent literature were analyzed retrospectively. Results: Resection of the tracheal tumor and reconstruction of the trachea were performed successfully in this case, and the pathological diagnosis is plasmocytoma. Conclusion: The nature, location and extent of tracheal tumor are precisely determined from radiologic studies before resection, as well as tracheal intubation and tracheal anastomosis without tension in operative procedures, are very important for triumphal operation. Even extramedullary plasmocytoma may occur in a lot of organs, but the incidence of it is rare. Both surgery and radiotherapy are cardinal methods for extramedullary plasmocytoma.展开更多
Extramedullary plasmacytoma （EMP） is an uncommon tumor that often develops outside the bone and arises from clonal proliferation of atypical plasma cells before EMP is diagnosed. Multiple myeloma （MM） must be excl...Extramedullary plasmacytoma （EMP） is an uncommon tumor that often develops outside the bone and arises from clonal proliferation of atypical plasma cells before EMP is diagnosed. Multiple myeloma （MM） must be excluded by performing laboratory tests such as serum protein electrophoresis, bone marrow biopsy and skeletal imaging examinations. A bone marrow biopsy should show no evidence of multiple myeloma, and less than 3% of plasma cells. Monoclonal bands of serum protein and Bence-Jones protein in the urine can sometimes be detected. EMP can involve any extraosseous organs, but it predominantly affects the head and neck areas. Any extra-osseous organ may also be involved. Tracheal involvement is a rare finding. Only a few cases of primary tracheal extramedullary plasmcytoma have been reportedE2-41, Here we present a rare case of truly localized tracheal extramedullary plasmacytoma without evidence of myeloma elsewhere.展开更多
Anesthesia for low tracheal tumor surgery presents many challenges: conventional anesthetic techniques would be catastrophic if one attempts to insert a tracheal tube which may cause a complete obstruction of the airw...Anesthesia for low tracheal tumor surgery presents many challenges: conventional anesthetic techniques would be catastrophic if one attempts to insert a tracheal tube which may cause a complete obstruction of the airway; on the other hand, tracheotomy usually can not pass beyond the obstruction. So how to get an adequate gas exchange as well as a good surgical access is what we must resolve during operation. In recent years, cardiopulmonary bypass (CPB) is not only used in cardiac surgery, but also becomes an attractive technique to facilitate non-cardiac surgery. 1-4 Here we report an emergent operation for resection of low tracheal tumor which was successfully performed under partial CPB in July 2004.展开更多
文摘BACKGROUND Tracheal neoplasms represent less than 0.1%of all malignancies and have no established treatment guidelines.Surgical resection with reconstruction is the primary treatment.This study demonstrates successful treatment of concurrent lung and tracheal tumors using surgical excision and intraoperative photodynamic therapy(PDT),highlighting the effectiveness and safety of this approach.CASE SUMMARY A 74-year-old male with a history of smoking and chronic obstructive pulmonary disease was diagnosed with tracheal squamous cell carcinoma and right lower lobe adenocarcinoma.A multidisciplinary team created a treatment plan involving tumor resection and PDT.The tracheal tumor was removed through a tracheal incision and this was followed by intraluminal PDT.The trachea was repaired and a right lower lobectomy was performed.The patient received a second PDT treatment postoperatively and was discharged 10 d after the tracheal surgery,without complications.He then underwent platinum-based chemotherapy for lymphovascular invasion of lung cancer.Three-month postoperative bronchoscopy revealed normal tracheal mucosa with a scar at the resection site and no evidence of tumor recurrence in the trachea or lung.CONCLUSION Our case of concurrent tracheal and lung cancers was successfully treated with surgical excision and intraoperative PDT which proved safe and effective in this patient.
文摘Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and pertinent literature were analyzed retrospectively. Results: Resection of the tracheal tumor and reconstruction of the trachea were performed successfully in this case, and the pathological diagnosis is plasmocytoma. Conclusion: The nature, location and extent of tracheal tumor are precisely determined from radiologic studies before resection, as well as tracheal intubation and tracheal anastomosis without tension in operative procedures, are very important for triumphal operation. Even extramedullary plasmocytoma may occur in a lot of organs, but the incidence of it is rare. Both surgery and radiotherapy are cardinal methods for extramedullary plasmocytoma.
文摘Extramedullary plasmacytoma （EMP） is an uncommon tumor that often develops outside the bone and arises from clonal proliferation of atypical plasma cells before EMP is diagnosed. Multiple myeloma （MM） must be excluded by performing laboratory tests such as serum protein electrophoresis, bone marrow biopsy and skeletal imaging examinations. A bone marrow biopsy should show no evidence of multiple myeloma, and less than 3% of plasma cells. Monoclonal bands of serum protein and Bence-Jones protein in the urine can sometimes be detected. EMP can involve any extraosseous organs, but it predominantly affects the head and neck areas. Any extra-osseous organ may also be involved. Tracheal involvement is a rare finding. Only a few cases of primary tracheal extramedullary plasmcytoma have been reportedE2-41, Here we present a rare case of truly localized tracheal extramedullary plasmacytoma without evidence of myeloma elsewhere.
文摘Anesthesia for low tracheal tumor surgery presents many challenges: conventional anesthetic techniques would be catastrophic if one attempts to insert a tracheal tube which may cause a complete obstruction of the airway; on the other hand, tracheotomy usually can not pass beyond the obstruction. So how to get an adequate gas exchange as well as a good surgical access is what we must resolve during operation. In recent years, cardiopulmonary bypass (CPB) is not only used in cardiac surgery, but also becomes an attractive technique to facilitate non-cardiac surgery. 1-4 Here we report an emergent operation for resection of low tracheal tumor which was successfully performed under partial CPB in July 2004.
