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Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints 被引量:1
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作者 Jin-Xi Zhang Kai-Di Xu Qing-Guo Wang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第7期1557-1565,共9页
The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requ... The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this paper.Herein, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings. 展开更多
关键词 Nonlinear systems output constraints prescribed performance reference tracking time delays
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Label-free in-vivo classi-cation and tracking of red blood cells and platelets using Dynamic-YOLOv4 network 被引量:1
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作者 Caizhong Guan Bin He +6 位作者 Hongting Zhang Shangpan Yang Yang Xu Honglian Xiong Yaguang Zeng Mingyi Wang Xunbin Wei 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第5期89-103,共15页
In-vivo flow cytometry is a noninvasive real-time diagnostic technique that facilitates continuous monitoring of cells without perturbing their natural biological environment,which renders it a valuable tool for both ... In-vivo flow cytometry is a noninvasive real-time diagnostic technique that facilitates continuous monitoring of cells without perturbing their natural biological environment,which renders it a valuable tool for both scientific research and clinical applications.However,the conventional approach for improving classification accuracy often involves labeling cells with fluorescence,which can lead to potential phototoxicity.This study proposes a label-free in-vivo flow cytometry technique,called dynamic YOLOv4(D-YOLOv4),which improves classification accuracy by integrating absorption intensity fluctuation modulation(AIFM)into YOLOv4 to demodulate the temporal features of moving red blood cells(RBCs)and platelets.Using zebrafish as an experimental model,the D-YOLOv4 method achieved average precisions(APs)of 0.90 for RBCs and 0.64 for thrombocytes(similar to platelets in mammals),resulting in an overall AP of 0.77.These scores notably surpass those attained by alternative network models,thereby demonstrating that the combination of physical models with neural networks provides an innovative approach toward developing label-free in-vivoflow cytometry,which holds promise for diverse in-vivo cell classification applications. 展开更多
关键词 LABEL-FREE in-vivoflow cytometry cell classification and tracking D-YOLOv4
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Masked Autoencoders as Single Object Tracking Learners 被引量:1
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作者 Chunjuan Bo XinChen Junxing Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第7期1105-1122,共18页
Significant advancements have beenwitnessed in visual tracking applications leveragingViT in recent years,mainly due to the formidablemodeling capabilities of Vision Transformer(ViT).However,the strong performance of ... Significant advancements have beenwitnessed in visual tracking applications leveragingViT in recent years,mainly due to the formidablemodeling capabilities of Vision Transformer(ViT).However,the strong performance of such trackers heavily relies on ViT models pretrained for long periods,limitingmore flexible model designs for tracking tasks.To address this issue,we propose an efficient unsupervised ViT pretraining method for the tracking task based on masked autoencoders,called TrackMAE.During pretraining,we employ two shared-parameter ViTs,serving as the appearance encoder and motion encoder,respectively.The appearance encoder encodes randomly masked image data,while the motion encoder encodes randomly masked pairs of video frames.Subsequently,an appearance decoder and a motion decoder separately reconstruct the original image data and video frame data at the pixel level.In this way,ViT learns to understand both the appearance of images and the motion between video frames simultaneously.Experimental results demonstrate that ViT-Base and ViT-Large models,pretrained with TrackMAE and combined with a simple tracking head,achieve state-of-the-art(SOTA)performance without additional design.Moreover,compared to the currently popular MAE pretraining methods,TrackMAE consumes only 1/5 of the training time,which will facilitate the customization of diverse models for tracking.For instance,we additionally customize a lightweight ViT-XS,which achieves SOTA efficient tracking performance. 展开更多
关键词 Visual object tracking vision transformer masked autoencoder visual representation learning
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Adaptive Trajectory Tracking Control for Nonholonomic Wheeled Mobile Robots:A Barrier Function Sliding Mode Approach 被引量:1
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作者 Yunjun Zheng Jinchuan Zheng +3 位作者 Ke Shao Han Zhao Hao Xie Hai Wang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1007-1021,共15页
The trajectory tracking control performance of nonholonomic wheeled mobile robots(NWMRs)is subject to nonholonomic constraints,system uncertainties,and external disturbances.This paper proposes a barrier function-base... The trajectory tracking control performance of nonholonomic wheeled mobile robots(NWMRs)is subject to nonholonomic constraints,system uncertainties,and external disturbances.This paper proposes a barrier function-based adaptive sliding mode control(BFASMC)method to provide high-precision,fast-response performance and robustness for NWMRs.Compared with the conventional adaptive sliding mode control,the proposed control strategy can guarantee that the sliding mode variables converge to a predefined neighborhood of origin with a predefined reaching time independent of the prior knowledge of the uncertainties and disturbances bounds.Another advantage of the proposed algorithm is that the control gains can be adaptively adjusted to follow the disturbances amplitudes thanks to the barrier function.The benefit is that the overestimation of control gain can be eliminated,resulting in chattering reduction.Moreover,a modified barrier function-like control gain is employed to prevent the input saturation problem due to the physical limit of the actuator.The stability analysis and comparative experiments demonstrate that the proposed BFASMC can ensure the prespecified convergence performance of the NWMR system output variables and strong robustness against uncertainties/disturbances. 展开更多
关键词 Adaptive sliding mode barrier function nonholonomic wheeled mobile robot(NWMR) trajectory tracking control
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Trajectory tracking guidance of interceptor via prescribed performance integral sliding mode with neural network disturbance observer 被引量:1
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作者 Wenxue Chen Yudong Hu +1 位作者 Changsheng Gao Ruoming An 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期412-429,共18页
This paper investigates interception missiles’trajectory tracking guidance problem under wind field and external disturbances in the boost phase.Indeed,the velocity control in such trajectory tracking guidance system... This paper investigates interception missiles’trajectory tracking guidance problem under wind field and external disturbances in the boost phase.Indeed,the velocity control in such trajectory tracking guidance systems of missiles is challenging.As our contribution,the velocity control channel is designed to deal with the intractable velocity problem and improve tracking accuracy.The global prescribed performance function,which guarantees the tracking error within the set range and the global convergence of the tracking guidance system,is first proposed based on the traditional PPF.Then,a tracking guidance strategy is derived using the integral sliding mode control techniques to make the sliding manifold and tracking errors converge to zero and avoid singularities.Meanwhile,an improved switching control law is introduced into the designed tracking guidance algorithm to deal with the chattering problem.A back propagation neural network(BPNN)extended state observer(BPNNESO)is employed in the inner loop to identify disturbances.The obtained results indicate that the proposed tracking guidance approach achieves the trajectory tracking guidance objective without and with disturbances and outperforms the existing tracking guidance schemes with the lowest tracking errors,convergence times,and overshoots. 展开更多
关键词 BP network neural Integral sliding mode control(ISMC) Missile defense Prescribed performance function(PPF) State observer tracking guidance system
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Privacy Protection in COVID Data Tracking: Textual Analysis of the Literature
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作者 Antonella Massari Viviana D’Addosio +1 位作者 Vittoria Claudia De Nicolò Samuela L’Abbate 《Applied Mathematics》 2024年第3期235-255,共21页
The literary review presented in the following paper aims to analyze the tracking tools used in different countries during the period of the COVID-19 pandemic. Tracking apps that have been adopted in many countries to... The literary review presented in the following paper aims to analyze the tracking tools used in different countries during the period of the COVID-19 pandemic. Tracking apps that have been adopted in many countries to collect data in a homogeneous and immediate way have made up for the difficulty of collecting data and standardizing evaluation criteria. However, the regulation on the protection of personal data in the health sector and the adoption of the new General Data Protection Regulation in European countries has placed a strong limitation on their use. This has not been the case in non-European countries, where monitoring methodologies have become widespread. The textual analysis presented is based on co-occurrence and multiple correspondence analysis to show the contact tracing methods adopted in different countries in the pandemic period by relating them to the issue of privacy. It also analyzed the possibility of applying Blockchain technology in applications for tracking contagions from COVID-19 and managing health data to provide a high level of security and transparency, including through anonymization, thus increasing user trust in using the apps. 展开更多
关键词 tracking PRIVACY Blockchain Textual Analysis
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FPGA and computer-vision-based atom tracking technology for scanning probe microscopy
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作者 俞风度 刘利 +5 位作者 王肃珂 张新彪 雷乐 黄远志 马瑞松 郇庆 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期76-85,共10页
Atom tracking technology enhanced with innovative algorithms has been implemented in this study,utilizing a comprehensive suite of controllers and software independently developed domestically.Leveraging an on-board f... Atom tracking technology enhanced with innovative algorithms has been implemented in this study,utilizing a comprehensive suite of controllers and software independently developed domestically.Leveraging an on-board field-programmable gate array(FPGA)with a core frequency of 100 MHz,our system facilitates reading and writing operations across 16 channels,performing discrete incremental proportional-integral-derivative(PID)calculations within 3.4 microseconds.Building upon this foundation,gradient and extremum algorithms are further integrated,incorporating circular and spiral scanning modes with a horizontal movement accuracy of 0.38 pm.This integration enhances the real-time performance and significantly increases the accuracy of atom tracking.Atom tracking achieves an equivalent precision of at least 142 pm on a highly oriented pyrolytic graphite(HOPG)surface under room temperature atmospheric conditions.Through applying computer vision and image processing algorithms,atom tracking can be used when scanning a large area.The techniques primarily consist of two algorithms:the region of interest(ROI)-based feature matching algorithm,which achieves 97.92%accuracy,and the feature description-based matching algorithm,with an impressive 99.99%accuracy.Both implementation approaches have been tested for scanner drift measurements,and these technologies are scalable and applicable in various domains of scanning probe microscopy with broad application prospects in the field of nanoengineering. 展开更多
关键词 atom tracking FPGA computer vision drift measurement
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Beam Training and Tracking in mmWave Communication:A Survey
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作者 Wang Yi Wei Zhiqing Feng Zhiyong 《China Communications》 SCIE CSCD 2024年第6期1-22,共22页
Communicating on millimeter wave(mmWave)bands is ushering in a new epoch of mobile communication which provides the availability of 10 Gbps high data rate transmission.However,mmWave links are easily prone to short tr... Communicating on millimeter wave(mmWave)bands is ushering in a new epoch of mobile communication which provides the availability of 10 Gbps high data rate transmission.However,mmWave links are easily prone to short transmission range communication because of the serious free space path loss and the blockage by obstacles.To overcome these challenges,highly directional beams are exploited to achieve robust links by hybrid beamforming.Accurately aligning the transmitter and receiver beams,i.e.beam training,is vitally important to high data rate transmission.However,it may cause huge overhead which has negative effects on initial access,handover,and tracking.Besides,the mobility patterns of users are complicated and dynamic,which may cause tracking error and large tracking latency.An efficient beam tracking method has a positive effect on sustaining robust links.This article provides an overview of the beam training and tracking technologies on mmWave bands and reveals the insights for future research in the 6th Generation(6G)mobile network.Especially,some open research problems are proposed to realize fast,accurate,and robust beam training and tracking.We hope that this survey provides guidelines for the researchers in the area of mmWave communications. 展开更多
关键词 6G beam tracking beam training BEAMFORMING mmWave
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A Retrodirective Array Enabled by CMOS Chips for Two-Way Wireless Communication with Automatic Beam Tracking
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作者 Jiacheng Guo Yizhu Shen +2 位作者 Guoqing Dong Zhuang Han Sanming Hu 《Engineering》 SCIE EI CAS CSCD 2024年第6期196-207,共12页
This article proposes and demonstrates a retrodirective array(RDA)for two-way wireless communication with automatic beam tracking.The proposed RDA is enabled by specifically designed chips made using a domestic comple... This article proposes and demonstrates a retrodirective array(RDA)for two-way wireless communication with automatic beam tracking.The proposed RDA is enabled by specifically designed chips made using a domestic complementary metal-oxide semiconductor(CMOS)process.The highly integrated CMOS chip includes a receiving(Rx)chain,a transmitting(Tx)chain,and a unique tracking phaselocked loop(PLL)for the crucial conjugated phase recovery in the RDA.This article also proposes a method to reduce the beam pointing error(BPE)in a conventional RDA.To validate the above ideas simply yet without loss of generality,a 2.4 GHz RDA is demonstrated through two-way communication links between the Rx and Tx chains,and an on-chip quadrature coupler is designed to achieve a nonretrodirective signal suppression of 23 dBc.The experimental results demonstrate that the proposed RDA,which incorporates domestically manufactured low-cost 0.18 lm CMOS chips,is capable of automatically tracking beams covering±40with a reduced BPE.Each CMOS chip in the RDA has a compact size of 4.62 mm^(2) and a low power consumption of 0.15 W.To the best of the authors’knowledge,this is the first research to demonstrate an RDA with a fully customized CMOS chip for wireless communication with automatic beam tracking。 展开更多
关键词 Automatic beam tracking CMOS Retrodirective array Two-way communication
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Automatic velocity picking based on optimal key points tracking algorithm
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作者 Yong-Hao Wang Wen-Kai Lu +3 位作者 Song-Bai Jin Yang Li Yu-Xuan Li Xiao-Feng Gu 《Petroleum Science》 SCIE EI CAS CSCD 2024年第2期903-917,共15页
Picking velocities from semblances manually is laborious and necessitates experience. Although various methods for automatic velocity picking have been developed, there remains a challenge in efficiently incorporating... Picking velocities from semblances manually is laborious and necessitates experience. Although various methods for automatic velocity picking have been developed, there remains a challenge in efficiently incorporating information from nearby gathers to ensure picked velocity aligns with seismic horizons while also improving picking accuracy. The conventional method of velocity picking from a semblance volume is computationally demanding, highlighting a need for a more efficient strategy. In this study, we introduce a novel method for automatic velocity picking based on multi-object tracking. This dynamic tracking process across different semblance panels can integrate information from nearby gathers effectively while maintaining computational efficiency. First, we employ accelerated density clustering on the velocity spectrum to discern cluster centers without the requirement for prior knowledge regarding the number of clusters. These cluster centers embody the maximum likelihood velocities of the main subsurface structures. Second, our proposed method tracks key points within the semblance volume. Kalman filter is adopted to adjust the tracking process, followed by interpolation on these tracked points to construct the final velocity model. Our synthetic data example demonstrates that our proposed algorithm can effectively rectify the picking errors of the clustering algorithm. We further compare the performances of the clustering method(CM), the proposed tracking method(TM), and the variational method(VM) on a field dataset from the Gulf of Mexico. The results attest that our method offers superior accuracy than CM, achieves comparable accuracy with VM, and benefits from a reduced computational cost. 展开更多
关键词 Velocity picking Multi-object tracking Density clustering Kalman filter
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SMSTracker:A Self-Calibration Multi-Head Self-Attention Transformer for Visual Object Tracking
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作者 Zhongyang Wang Hu Zhu Feng Liu 《Computers, Materials & Continua》 SCIE EI 2024年第7期605-623,共19页
Visual object tracking plays a crucial role in computer vision.In recent years,researchers have proposed various methods to achieve high-performance object tracking.Among these,methods based on Transformers have becom... Visual object tracking plays a crucial role in computer vision.In recent years,researchers have proposed various methods to achieve high-performance object tracking.Among these,methods based on Transformers have become a research hotspot due to their ability to globally model and contextualize information.However,current Transformer-based object tracking methods still face challenges such as low tracking accuracy and the presence of redundant feature information.In this paper,we introduce self-calibration multi-head self-attention Transformer(SMSTracker)as a solution to these challenges.It employs a hybrid tensor decomposition self-organizing multihead self-attention transformermechanism,which not only compresses and accelerates Transformer operations but also significantly reduces redundant data,thereby enhancing the accuracy and efficiency of tracking.Additionally,we introduce a self-calibration attention fusion block to resolve common issues of attention ambiguities and inconsistencies found in traditional trackingmethods,ensuring the stability and reliability of tracking performance across various scenarios.By integrating a hybrid tensor decomposition approach with a self-organizingmulti-head self-attentive transformer mechanism,SMSTracker enhances the efficiency and accuracy of the tracking process.Experimental results show that SMSTracker achieves competitive performance in visual object tracking,promising more robust and efficient tracking systems,demonstrating its potential to providemore robust and efficient tracking solutions in real-world applications. 展开更多
关键词 Visual object tracking tensor decomposition TRANSFORMER self-attention
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Reinforcement learning based adaptive control for uncertain mechanical systems with asymptotic tracking
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作者 Xiang-long Liang Zhi-kai Yao +1 位作者 Yao-wen Ge Jian-yong Yao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期19-28,共10页
This paper mainly focuses on the development of a learning-based controller for a class of uncertain mechanical systems modeled by the Euler-Lagrange formulation.The considered system can depict the behavior of a larg... This paper mainly focuses on the development of a learning-based controller for a class of uncertain mechanical systems modeled by the Euler-Lagrange formulation.The considered system can depict the behavior of a large class of engineering systems,such as vehicular systems,robot manipulators and satellites.All these systems are often characterized by highly nonlinear characteristics,heavy modeling uncertainties and unknown perturbations,therefore,accurate-model-based nonlinear control approaches become unavailable.Motivated by the challenge,a reinforcement learning(RL)adaptive control methodology based on the actor-critic framework is investigated to compensate the uncertain mechanical dynamics.The approximation inaccuracies caused by RL and the exogenous unknown disturbances are circumvented via a continuous robust integral of the sign of the error(RISE)control approach.Different from a classical RISE control law,a tanh(·)function is utilized instead of a sign(·)function to acquire a more smooth control signal.The developed controller requires very little prior knowledge of the dynamic model,is robust to unknown dynamics and exogenous disturbances,and can achieve asymptotic output tracking.Eventually,co-simulations through ADAMS and MATLAB/Simulink on a three degrees-of-freedom(3-DOF)manipulator and experiments on a real-time electromechanical servo system are performed to verify the performance of the proposed approach. 展开更多
关键词 Adaptive control Reinforcement learning Uncertain mechanical systems Asymptotic tracking
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Determination of liquid viscosity based on dual-frequency-bandparticle tracking
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作者 Lihua Yan Boyin Xue +3 位作者 Yuanji Li Jinxia Feng Xingkang Wu Kuanshou Zhang 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期359-364,共6页
An optical-tweezers-based dual-frequency-band particle tracking system was designed and fabricated for liquid viscositydetection. On the basis of the liquid viscosity dependent model of the particle’s restricted Brow... An optical-tweezers-based dual-frequency-band particle tracking system was designed and fabricated for liquid viscositydetection. On the basis of the liquid viscosity dependent model of the particle’s restricted Brownian motion with theFax´en correction taken into account, the liquid viscosity and optical trap stiffness were determined by fitting the theoreticalprediction with the measured power spectral densities of the particle’s displacement and velocity that were derived from thedual-frequency-band particle tracking data. When the SiO2 beads were employed as probe particles in the measurements ofdifferent kinds of liquids, the measurement results exhibit a good agreement with the reported results, as well as a detectionuncertainty better than 4.6%. This kind of noninvasive economical technique can be applied in diverse environments forboth in situ and ex situ viscosity detection of liquids. 展开更多
关键词 liquid viscosity optical tweezers dual-frequency-band particle tracking power spectral density
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Efficient 2-D MUSIC algorithm for super-resolution moving target tracking based on an FMCW radar
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作者 Xuchong Yi Shuangxi Zhang Yuxuan Zhou 《Geodesy and Geodynamics》 EI CSCD 2024年第5期504-515,共12页
Frequency modulated continuous wave(FMCW)radar is an advantageous sensor scheme for target estimation and environmental perception.However,existing algorithms based on discrete Fourier transform(DFT),multiple signal c... Frequency modulated continuous wave(FMCW)radar is an advantageous sensor scheme for target estimation and environmental perception.However,existing algorithms based on discrete Fourier transform(DFT),multiple signal classification(MUSIC)and compressed sensing,etc.,cannot achieve both low complexity and high resolution simultaneously.This paper proposes an efficient 2-D MUSIC algorithm for super-resolution target estimation/tracking based on FMCW radar.Firstly,we enhance the efficiency of 2-D MUSIC azimuth-range spectrum estimation by incorporating 2-D DFT and multi-level resolution searching strategy.Secondly,we apply the gradient descent method to tightly integrate the spatial continuity of object motion into spectrum estimation when processing multi-epoch radar data,which improves the efficiency of continuous target tracking.These two approaches have improved the algorithm efficiency by nearly 2-4 orders of magnitude without losing accuracy and resolution.Simulation experiments are conducted to validate the effectiveness of the algorithm in both single-epoch estimation and multi-epoch tracking scenarios. 展开更多
关键词 2D-MUSIC FMCW radar Moving target tracking SUPER-RESOLUTION Algorithm optimization
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LQTTrack:Multi-Object Tracking by Focusing on Low-Quality Targets Association
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作者 Suya Li Ying Cao +2 位作者 Hengyi Ren Dongsheng Zhu Xin Xie 《Computers, Materials & Continua》 SCIE EI 2024年第10期1449-1470,共22页
Multi-object tracking(MOT)has seen rapid improvements in recent years.However,frequent occlusion remains a significant challenge in MOT,as it can cause targets to become smaller or disappear entirely,resulting in lowq... Multi-object tracking(MOT)has seen rapid improvements in recent years.However,frequent occlusion remains a significant challenge in MOT,as it can cause targets to become smaller or disappear entirely,resulting in lowquality targets,leading to trajectory interruptions and reduced tracking performance.Different from some existing methods,which discarded the low-quality targets or ignored low-quality target attributes.LQTTrack,with a lowquality association strategy(LQA),is proposed to pay more attention to low-quality targets.In the association scheme of LQTTrack,firstly,multi-scale feature fusion of FPN(MSFF-FPN)is utilized to enrich the feature information and assist in subsequent data association.Secondly,the normalized Wasserstein distance(NWD)is integrated to replace the original Inter over Union(IoU),thus overcoming the limitations of the traditional IoUbased methods that are sensitive to low-quality targets with small sizes and enhancing the robustness of low-quality target tracking.Moreover,the third association stage is proposed to improve the matching between the current frame’s low-quality targets and previously interrupted trajectories from earlier frames to reduce the problem of track fragmentation or error tracking,thereby increasing the association success rate and improving overall multi-object tracking performance.Extensive experimental results demonstrate the competitive performance of LQTTrack on benchmark datasets(MOT17,MOT20,and DanceTrack). 展开更多
关键词 Low-quality targets association strategy feature fusion multi-object tracking tracking-by-detection
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Ultrasound-activated in situ click chemistry to trigger autophagosome tracking for enhanced autophagy blockade and synergistic cancer therapy
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作者 Weixi Jiang Jingxue Wang +13 位作者 Li Chen Xiaoling Qiu Chier Du Hongjin An Xun Guo Xiaoting Wang Junrui Wang Pan Li Zhigang Wang Haitao Ran Zhiyi Zhou Xiaoyuan Chen Jingjing Zhang Jianli Ren 《Aggregate》 EI CAS 2024年第4期386-398,共13页
The blockade of cytoprotective autophagy has been demonstrated to effectively enhance the efficacy of sonodynamic therapy(SDT).However,the limited recogni-tion of antiautophagy agents for autophagosomes impedes the cli... The blockade of cytoprotective autophagy has been demonstrated to effectively enhance the efficacy of sonodynamic therapy(SDT).However,the limited recogni-tion of antiautophagy agents for autophagosomes impedes the clinical application of autophagy inhibition.To efficiently deliver hydroxychloroquine(HCQ),an autophagy inhibitor,to autophagosomes,we utilized a strategy based on in situ click chemistry between sulfhydryl(-SH)and maleimide(Mal)groups to trigger autophagosomes tracking and suppress tumor growth synergistically.A cascade nanoreactor was synthesized by encapsulating Mal-modified HCQ(MHCQ)into a manganese porphyrin-based metal-organic framework with sonosensitizer proper-ties,followed by poly(ethylene glycol)ylated liposomal membrane coating.After ultrasound irradiation,SDT-induced apoptotic cells released damaged proteins with free-SH groups,which MHCQ rapidly captured in situ via a Mal-thiol click reaction.When autophagosomes actively wrapped damaged proteins for detoxifi-cation,they simultaneously internalized HCQ anchored on proteins.In this scenario,antiautophagy drugs could actively track intracellular autophagosomes instead of undergoing passive diffusion in the cytosol.The interaction between HCQ and autophagic vesicles was greatly enhanced,which strengthened the blocking effi-ciency of autophagy and resulted in complete cell death.Overall,this study with smart design provides a promising strategy for improving intracellular targeted delivery to autophagosomes,thereby enhancing antitumor therapy. 展开更多
关键词 autophagosomes tracking autophagy blockade click reaction sonodynamic therapy synergy
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Investigation of Inside-Out Tracking Methods for Six Degrees of Freedom Pose Estimation of a Smartphone in Augmented Reality
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作者 Chanho Park Takefumi Ogawa 《Computers, Materials & Continua》 SCIE EI 2024年第5期3047-3065,共19页
Six degrees of freedom(6DoF)input interfaces are essential formanipulating virtual objects through translation or rotation in three-dimensional(3D)space.A traditional outside-in tracking controller requires the instal... Six degrees of freedom(6DoF)input interfaces are essential formanipulating virtual objects through translation or rotation in three-dimensional(3D)space.A traditional outside-in tracking controller requires the installation of expensive hardware in advance.While inside-out tracking controllers have been proposed,they often suffer from limitations such as interaction limited to the tracking range of the sensor(e.g.,a sensor on the head-mounted display(HMD))or the need for pose value modification to function as an input interface(e.g.,a sensor on the controller).This study investigates 6DoF pose estimation methods without restricting the tracking range,using a smartphone as a controller in augmented reality(AR)environments.Our approach involves proposing methods for estimating the initial pose of the controller and correcting the pose using an inside-out tracking approach.In addition,seven pose estimation algorithms were presented as candidates depending on the tracking range of the device sensor,the tracking method(e.g.,marker recognition,visual-inertial odometry(VIO)),and whether modification of the initial pose is necessary.Through two experiments(discrete and continuous data),the performance of the algorithms was evaluated.The results demonstrate enhanced final pose accuracy achieved by correcting the initial pose.Furthermore,the importance of selecting the tracking algorithm based on the tracking range of the devices and the actual input value of the 3D interaction was emphasized. 展开更多
关键词 SMARTPHONE inside-out tracking 6DoF pose 3D interaction augmented reality
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Path Tracking Controller Design of Automated Parking Systems via NMPC with an Instructible Solution
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作者 Liang Chen Zhaobo Qin +2 位作者 Manjiang Hu Yougang Bian Xiaoyan Peng 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第3期353-367,共15页
Parking difficulties have become a social issue that people have to solve.Automated parking system is practicable for quick par operations without a driver which can also greatly reduces the probability of parking acc... Parking difficulties have become a social issue that people have to solve.Automated parking system is practicable for quick par operations without a driver which can also greatly reduces the probability of parking accidents.The paper proposes a Lyapunov-based nonlinear model predictive controller embedding an instructable solution which is generated by the modified rear-wheel feedback method(RF-LNMPC)in order to improve the overall path tracking accuracy in parking conditions.Firstly,A discrete-time RF-LNMPC considering the position and attitude of the parking vehicle is proposed to increase the success rate of automated parking effectively.Secondly,the RF-LNMPC problem with a multi-objective cost function is solved by the Interior-Point Optimization,of which the iterative initial values are described as the instructable solutions calculated by combining modified rear-wheel feedback to improve the performance of local optimal solution.Thirdly,the details on the computation of the terminal constraint and terminal cost for the linear time-varying case is presented.The closed-loop stability is verified via Lyapunov techniques by considering the terminal constraint and terminal cost theoretically.Finally,the proposed RF-LNMPC is implemented on a selfdriving Lincoln MKZ platform and the experiment results have shown improved performance in parallel and vertical parking conditions.The Monte Carlo analysis also demonstrates good stability and repeatability of the proposed method which can be applied in practical use in the near future. 展开更多
关键词 Automated parking Path tracking controller Nonlinear model predictive control Monte Carlo analysis
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Practical Prescribed Time Tracking Control With Bounded Time-Varying Gain Under Non-Vanishing Uncertainties
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作者 Dahui Luo Yujuan Wang Yongduan Song 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期219-230,共12页
This paper investigates the prescribed-time control(PTC) problem for a class of strict-feedback systems subject to non-vanishing uncertainties. The coexistence of mismatched uncertainties and non-vanishing disturbance... This paper investigates the prescribed-time control(PTC) problem for a class of strict-feedback systems subject to non-vanishing uncertainties. The coexistence of mismatched uncertainties and non-vanishing disturbances makes PTC synthesis nontrivial. In this work, a control method that does not involve infinite time-varying gain is proposed, leading to a practical and global prescribed time tracking control solution for the strict-feedback systems, in spite of both the mismatched and nonvanishing uncertainties. Different from methods based on control switching to avoid the issue of infinite control gain that involves control discontinuity at the switching point, in our method a softening unit is exclusively included to ensure the continuity of the control action. Furthermore, in contrast to most existing prescribed-time control works where the control scheme is only valid on a finite time interval, in this work, the proposed control scheme is valid on the entire time interval. In addition, the prior information on the upper or lower bound of gi is not in need,enlarging the applicability of the proposed method. Both the theoretical analysis and numerical simulation confirm the effectiveness of the proposed control algorithm. 展开更多
关键词 Adaptive control prescribed time control(PTC) strict-feedback systems tracking control
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Accurately tracking hypersonic gliding vehicles via an LEO mega-constellation in relay tracking mode
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作者 LI Zhao WANG Yidi ZHENG Wei 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2024年第1期211-221,共11页
In order to effectively defend against the threats of the hypersonic gliding vehicles(HGVs),HGVs should be tracked as early as possible,which is beyond the capability of the ground-based radars.Being benefited by the ... In order to effectively defend against the threats of the hypersonic gliding vehicles(HGVs),HGVs should be tracked as early as possible,which is beyond the capability of the ground-based radars.Being benefited by the developing megaconstellations in low-Earth orbit,this paper proposes a relay tracking mode to track HGVs to overcome the above problem.The whole tracking mission is composed of several tracking intervals with the same duration.Within each tracking interval,several appropriate satellites are dispatched to track the HGV.Satellites that are planned to take part in the tracking mission are selected by a new derived observability criterion.The tracking performances of the proposed tracking mode and the other two traditional tracking modes,including the stare and track-rate modes,are compared by simulation.The results show that the relay tracking mode can track the whole trajectory of a HGV,while the stare mode can only provide a very short tracking arc.Moreover,the relay tracking mode achieve higher tracking accuracy with fewer attitude controls than the track-rate mode. 展开更多
关键词 target tracking mega-constellation hypersonic gliding vehicle(HGV) sensor selection observability analysis
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