A Brief Discussion on the Construction of Practical Teaching System for the Traditional Chinese Medicine Resources and Development Major

China’s traditional medicine,science,and technology industry has great development potential.However,there is a problem of insufficient practitioners in the current industrial development.At the same time,the capabilities of existing practitioners do not match the demand standards.Therefore,it is necessary to actively promote the education of resources and development in Central Asia.As an institution for cultivating talents,colleges and universities must establish a practical teaching system for cultivating talents.Based on the requirements put forward by China in education,this article studies the development status of the traditional Chinese medicine resources and development major,determines the talent training goals,starts from the practical teaching aspect,and locates the industry’s requirements for the capabilities of personnel in the field of traditional Chinese medicine.It also puts forward the overall idea of the construction of the practical teaching system,summarizes the reform content of the practical teaching system,and lastly provides the specific path of the reform.

Explore the value and potential of traditional Chinese medicine against cancer with the methodology and practice spirit of natural science

Traditional Chinese medicine （TCM） is a life science with original characteristics of our nation, which has its own advantages in facing modern medicine. As a clinical discipline with distinct characteristics of life medical science, oncology is a typical discipline that combines the advantages of Chinese and Western medicine. TCM has two different cultural attributes, the humanities and the natural sciences. However, when confronted with such a serious disease as cancer, the approach of natural science of TCM should be emphasized to participate in anti-cancer practice.

On the Need to Integrate Traditional Chinese and Western Medicine, and Pool Research Resources

The Chinese Academy of Sci-ences (CAS) is implementing theknowledge innovation program(KIP) on a trial basis. In my opinion,our knowledge innovation targetsshould be first of all precise and,secondly, able to boost our work. Ispecialize in hematology and mo-lecular biology. Under the

Traditional Chinese medicines derived natural inhibitors of ferroptosis on ischemic stroke

Ischemic stroke(IS)is a globally prevalent cerebrovascular disorder resulting from cerebral vessel occlusion,leading to significant morbidity and mortality.The intricate pathological mechanisms underlying IS complicate the development of effective therapeutic interventions.Ferroptosis,a form of programmed cell death(PCD)characterized by iron overload and accumulation of lipid peroxidation products,has been increasingly recognized as a key contributor to IS pathology.Traditional Chinese medicines(TCMs)have long been utilized in the management of IS,prompting extensive research into their potential as sources of natural ferroptosis inhibitors.This review investigates the critical role of ferroptosis in IS and provides a comprehensive analysis of current research on natural ferroptosis inhibitors identified in TCMs,aiming to lay a theoretical groundwork for the development of innovative anti-IS therapies.

Nutritional and medicinal characteristics of Chinese giant salamander (Andrias davidianus) for applications in healthcare industry by artificial cultivation: A review

Andrias davidianus,i.e.Chinese giant salamander(CGS),is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China.Wild CGS has been threatened with extinction in the past decades due to over capturing,deterioration of natural environment,the slow breeding and growth of the wild species in nature.However,in the past twenty years,with the breakthrough and progress of artificial breeding technology by artificial insemination,the number of artificially cultivated CGS has increased rapidly.Artificially cultivated CGS can either be released to the CGS living environment to increase the population in nature or legally applied in food and medicinal industry as a feedstock due to the unique nutritional and medicinal values of CGS as recorded historically.In this review,the nutritional components,bioactive components and medicinal activities of the artificially cultivated CGS will be summarized.The mucus,skin,meat and bone of CGS contain many different bioactive substances thereby having various medicinal activities including anti-aging,anti-fatigue,anti-tumor,therapy of burn and anti-infection and other physiological functions.This paper will further discuss the potential applications of the artificially cultivated CGS in healthcare industry and prospects of future technological development.

Protection and Quality Control of Wild Chinese Herbal Medicine Resources in Nature Reserves by Taking Longyuwan Scenic Spot Within Funiu Mountain Nature Reserve as an Example

This paper discussed how to protect and control the quality of wild Chinese herbal medicine resources in nature reserves by taking Longyuwan National Forest Park within Funiu Mountain Nature Reserve as an example. Through the combination of three methods including literature review, visiting and investigational studies, and field surveys, the data of investigation, collection and collation were analyzed. According to data of surveys, collection and collation, problems related to the protection of wild Chinese herbal medicine resources faced by Longyuwan Scenic Spot within Funiu Mountain Nature Reserve were also analyzed and protection strategies and quality control of wild Chinese herbal medicine resources in this nature reserve were discussed. It was expected that the results would provide important scientific references for the sustainable development, protection and quality control of wild Chinese herbal medicine resources within nature reserves.

Traditional Chinese medicine Master XIONG Jibo’s medication experience in treating arthralgia syndrome through data mining

Objective This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine(TCM)Master XIONG Jibo in diagnosing and treat-ing arthralgia syndrome(AS)through data mining.Methods Data of outpatient cases of Professor XIONG Jibo were collected from January 1,2014 to December 31,2018,along with cases recorded in A Real Famous Traditional Chinese Medicine Doctor:XIONG Jibo's Clinical Medical Record 1,which was published in December 2019.The five variables collected from the patients’data were TCM diagnostic information,TCM and western medicine diagnoses,syndrome,treatment,and prescription.A database was established for the collected data with Excel.Using the Python environment,a custom-ized modified natural language processing(NLP)model for the diagnosis and treatment of AS by Professor XIONG Jibo was established to preprocess the data and to analyze the word cloud.Frequency analysis,association rule analysis,cluster analysis,and visual analysis of AS cases were performed based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)and RStudio(V4.0.3).Results A total of 610 medical records of Professor XIONG Jibo were collected from the case database.A total of 103 medical records were included after data screening criteria,which comprised 187 times(45 kinds)of prescriptions and 1506 times(125 kinds)of Chinese herbs.The main related meridians were the liver,spleen,and kidney meridians.The properties of Chinese herbs used most were mainly warm,flat,and cold,while the flavors of herbs were mainly bitter,pungent,and sweet.The main patterns of AS included the damp heat,phlegm stasis,and neck arthralgia.The most commonly used herbs for AS were Chuanniuxi(Cyathu-lae Radix),Huangbo(Phellodendri Chinensis Cortex),Cangzhu(Atractylodis Rhizoma),Qinjiao(Gentianae Macrophyllae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangqi(Astragali Radix),and Chuanxiong(Chuanxiong Rhizoma).The most common effect of the herbs was“promoting blood circulation and removing blood stasis”,followed by“supple-menting deficiency(Qi supplementing,blood supplementing,and Yang supplementing)”,and“dispelling wind and dampness”.The data were analyzed with the support≥15%and con-fidence=100%,and after de-duplication,five second-order association rules,39 third-order association rules,39 fourth-order association rules,and two fifth-order association rules were identified.The top-ranking association rules of each were“Cangzhu(Atractylodis Rhizoma)→Huangbo(Phellodendri Chinensis Cortex)”“Cangzhu(Atractylodis Rhizoma)+Chuanniuxi(Cyathulae Radix)→Huangbo(Phellodendri Chinensis Cortex)”“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)→Qinjiao(Gentianae Macrophyllae Radix)”and“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)+Huangbo(Phello-dendri Chinensis Cortex)→Qinjiao(Gentianae Macrophyllae Radix)”,respectively.Five clusters were obtained using cluster analysis of the top 30 herbs.The herbs were mainly dry-ing dampness,supplementing Qi,and promoting blood circulation.The main prescriptions of AS were Ermiao San(二妙散),Gegen Jianghuang San(葛根姜黄散),and Huangqi Chongteng Yin(黄芪虫藤饮).The herbs of core prescription included Cangzhu(Atractylodis Rhizoma),Chuanniuxi(Cyathulae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangbo(Phellodendri Chinensis Cortex),Mugua(Chaenomelis Fructus),Qinjiao(Gentianae Macro-phyllae Radix),Danggui(Angelicae Sinensis Radix),and Yiyiren(Coicis Semen).Conclusion Clearing heat and dampness,relieving collaterals and pain,and invigorating Qi and blood are the most commonly used therapies for the treatment of AS by Professor XIONG Jibo.Additionally,customized NLP model could improve the efficiency of data mining in TCM.

Annual advances of traditional Chinese medicine on tumor immunity regulation in 2021

Traditional Chinese medicine has been used to treat more than 70%of cancer patients in China.Traditional Chinese medicine treatment includes the application of traditional Chinese medicine monomers,extracts,classical Chinese medicine compounds,self-made compounds,acupuncture,etc.Mechanisms of the anti-tumor effects of traditional Chinese medicine are related to their immune-regulatory roles.Some traditional Chinese medicines improve the sensitivity of chemotherapeutic drugs,enhance tumor-suppressive effects,and decrease adverse reactions.In 2021,research papers from China accounted for about two-thirds of all the papers on traditional Chinese medicine and anti-tumor immunity.China continues to lead the world in the field of anti-tumor immunity of traditional Chinese medicine,and the efficient and productive academic cooperation between China and other countries has promoted the rapid development of this field.In this review,we summarize the research progress of traditional Chinese medicine in the field of tumor immunity in 2021 to provide new insights into mechanisms underlying the anti-tumor effects of traditional Chinese medicine.

辽宁省海城市中药资源调查与分析

目的 通过对辽宁省海城市中药资源的普查,掌握海城市药用植物资源现状及部分重点品种的蕴藏量,为海城市中药资源的保护及可持续开发利用提供理论参考。方法 以第四次《全国中药资源普查技术规范》要求为标准制定普查方案,采用传统野外调查与现代技术相结合的方法,对海城市药用植物资源进行调查及数据分析。结果研究共完成了36个样地、180个样方套、1080个样方的调查,调查到药用植物452种,涉及86科290属;其中2020版《中华人民共和国药典》收载的重点调查品种112种,辽宁省新纪录植物2种。结论 海城市药用植物资源较为丰富,县域内大部分中药物种种群处于稳定状态,少数种群呈减少趋势,政府应采取措施加强动态监测与保护,普查工作的开展有助于县域内中药文化知识的推广普及,亦为海城市中药资源的可持续发展及开发利用提供科学依据。

陕西省第四次全国中药资源普查对秦药产业高质量发展的启示

通过对第四次全国中药资源普查陕西省相关工作成果进行梳理,明确了陕西省中药资源种类与构成情况,根据区域生境特点和生态适宜性提出秦药的适宜生产区划;总结了中药资源普查成果在陕西省乡村振兴和富民强省、中药产业合理布局和生产规划、中医药事业高质量可持续发展等方面的作用;最终,从加强种子种苗标准化研究、培育优良秦药品种,积极发展林下经济、构建中药材生态种植体系,引导秦药生产向绿色高效方向发展、促进秦药提质增效3个方面展望了秦药产业未来发展面临的挑战,为进一步聚焦秦药大品种、打造秦药全产业链、促进秦药产业绿色可持续发展提供科学参考。

中医药数据资源目录体系构建与研究

目的/意义规范中医药数据资源的有效管理和应用。方法/过程以中医药数据资源为主要研究对象,以目录学为研究方法,参考相关行业领域数据资源分类体系、中医药相关法律法规、中医药领域业务职能和学科分类等资料,提出中医药数据资源目录分类模型及主要内容。结果/结论初步建立中医药数据资源目录分类体系,为中医药数据资源目录数据库构建提供参考。

辽宁省鞍山市药用植物资源调查与分析

目的:通过调查辽宁省鞍山市药用植物资源的种类及分布状况,掌握鞍山市药用植物资源的特征,为该市的中药资源保护和可持续开发利用提供本底资料。方法:按照第四次全国中药资源普查技术规范的要求,制定普查方案,采用传统野外实地调查与现代技术相结合的方法,收集鞍山市药用植物资源的相关信息。结果:共完成174个样地、870个样方套、5220个样方的调查工作,全面覆盖鞍山市1个县级市、2个县、4个区的范围,记录到182科598属1228种药用植物;重点调查了药用植物132种,均为2020年版中国药典收载品种;5种属于辽宁省新记录物种。结论:鞍山市药用植物资源物种多样性较丰富,域内大部分中药资源种群处于稳定状态,但有少数种群呈减少的趋势,建议加强动态监测与资源保护,营造良好的中药资源生存空间和中医药文化氛围,共同推进药用植物资源的可持续发展。

2022年NSFC心血管领域中、西医申请资助情况分析

系统梳理分析2022年国家自然科学基金心血管领域中、西医学面上项目、青年科学基金项目和地区科学基金项目3类常规项目的申请和资助情况、所涉及主要病种、研究热点和研究思路。结果显示,两个领域研究的主要病种相似,研究热点也基本一致。均以动脉粥样硬化、冠心病、心力衰竭、高血压、继发性心肌损伤和心律失常为主,主要开展表观遗传学、外泌体、细胞焦亡或铁死亡、细胞自噬、肠道微生物群以及线粒体功能方面的研究,思路呈现多样化的特点。但西医心血管领域的病种更为广泛,还包括心脏移植等中医心血管领域不涉及的病种。在科学问题导向和研究内容方面,中医心血管领域要求在中医药理论的指导下,以解决中医学科的关键科学问题为导向,体现中医药的特色。此外,研究热点只是探索科学问题的技术手段,应深入凝练科学问题,避免盲目追求结合研究热点反而缺乏了创新性思想和科学依据,鼓励原创性基础研究。

长三角地区中医药卫生资源配置现状及运行效率分析

目的分析长三角地区中医药卫生资源配置现状和运行效率变化情况。方法采用描述性统计方法对2012—2021年长三角地区中医药卫生资源的配置现状进行分析,采用三阶段数据包络分析模型静态分析中医药卫生资源运行效率,采用Malmquist指数模型动态分析中医药卫生资源运行效率。结果长三角地区中医药卫生资源相对丰富,经过三阶段数据包络分析,江苏、浙江的综合效率、纯技术效率和规模效率基本均被低估;上海的纯技术效率、规模效率和综合效率基本均被高估;安徽的纯技术效率、规模效率和综合效率在2012—2016年被高估,2017—2021年被低估。经过Malmquist指数模型动态分析,2012—2021年长三角地区中医药卫生资源的全要素生产率指数在1.000上下波动,均值为0.984,运行效率呈下降趋势。结论长三角地区中医药卫生资源配置不均衡,利用差异化,效率不稳定。建议政府和卫生健康行政主管部门因地制宜,合理规划区域卫生,加强技术创新,提高医疗技术水平,提高中医药卫生资源配置运行效率。

山东海岸单叶蔓荆现状分析及保护对策

单叶蔓荆是蔓荆子药材的来源,也是重要的野生海岸保护植被,是聚社会、生态、药用价值于一体的重要资源。鉴于目前单叶蔓荆资源受到严重破坏实情,以第四次全国中药资源普查数据为基础,结合实地调研,对山东省单叶蔓荆资源分布情况和资源特点进行分析,并针对目前单叶蔓荆资源栖息地受损严重、种质资源单一、市场效益欠佳等主要问题,提出建立保护基地、选育新品种、多用途开发等多条针对性对策建议,旨在为沿海沙质海岸单叶蔓荆种源的保护和发展利用提供客观依据。

馆藏优秀传统文化资源再生性保护与价值释放——基于中医药古籍的调查分析

通过调查统计河南省各类图书馆、文博单位等中医药古籍资源存藏、保护、整理和利用情况,分析河南省中医药古籍资源馆藏开发整理存在的问题,提出“加强中医药古籍保护与利用工作的领导与统筹”“深入挖掘整理河南省中医药古籍资源”“确定重点保护对象,推进中医药古籍多层级保护”“加大中医药古籍保护领域复合型人才培养力度”“加强中医药古籍艺术与文化价值的发掘与传播”等推动河南省中医药发展的举措。

基于试卷分析探讨线上线下混合式教学效果——以“中药资源综合利用与产品开发”课程为例

定量分析了信阳农林学院中药资源与开发专业2019级2个班级的“中药资源综合利用与产品开发”课程期末考试的结果,评估了基于“三个阶段+三个目标+两性一度+认知提升”模式下的线上线下混合式教学改革的质量,为改进教学方法和提高考试试卷质量提供依据。结果显示,整套试卷难度系数为0.78,区分度为0.51,信度系数为0.94。以中药资源为原料的食品开发这一知识单元的得分率最高,达92.25%。可见,该试卷难度适中、区分度较好、可信有效,线上线下混合式教学改革质量可靠,有助于提高人才培养质量。

基于国家精品资源共享课的高等中医学科可重复混合式教学探讨

新型冠状病毒感染世界大流行已逾3年,各行各业均受到明显影响,高等医学教育就是其中之一。如今我国疫情防控措施已逐渐放开,各行业也迅速恢复生产,进入后疫情时代。高等医学院校高度专科化、实践化,尤其是中医学科。如何在这一特殊时期有效提高中医学生的理论水平与实践能力、提高中医学学科教学质量,是医学高等院校面临的困难。这一时期,互联网的发展更加迅猛,“互联网+”再次回到人们的视野。文章对“互联网+国家精品资源共享课”联合线下小规模中医实践课程的教与学新型关系的混合式教学进行了探讨,以期为医学高等院校提高中医学教学质量提供一种新型方式。

四川省通川区药用植物资源调查

目的:依托第四次全国中药资源普查(试点),采用野外样地调查和查阅文献资料等方法,对通川区中药植物资源进行调查,并对科、属组成类型、生活类型、组成特点、药用功效等多方面进行分析,旨在全面系统了解通川区中药材资源的分布情况。方法:通过选择双龙镇、盘石镇等共7个镇、3个乡、1个街道社区等区域,由全国中药资源普查信息管理系统随机生成41个样地,通过调查样方180个,样方套1080个,全面掌握通川区中药材资源的分布情况。结果:共完成36个样地调查,统计到通川区药用植物共775种,隶属于154科,533属,其中被子植物719种,蕨类植物44种,裸子植物12种。结论:通川区中药资源丰富,了解通川区中药材资源分布,可为持续开发利用提供了参考依据。