This article will present the result of 35 years of studies andresearch initiated by two teachers:Professor Leung KokYuen(China)and Professor Truong Thin(Vietnam).This article will briefly introduce the systems of tra...This article will present the result of 35 years of studies andresearch initiated by two teachers:Professor Leung KokYuen(China)and Professor Truong Thin(Vietnam).This article will briefly introduce the systems of traditional Chinese medicine,such as Jing(精),Xue(血),Qi(气),Shen(神)and Jin Ye(津液)compared with various systems in modern medicine.展开更多
Objective:To evaluate the efficacy and safety of Shen Zhi Ling oral liquid(SZL)alone or combined with basic treatment in treating Alzheimer's Disease(AD).Methods:Databases including PubMed,the Cochrane Library,Emb...Objective:To evaluate the efficacy and safety of Shen Zhi Ling oral liquid(SZL)alone or combined with basic treatment in treating Alzheimer's Disease(AD).Methods:Databases including PubMed,the Cochrane Library,Embase,Web of science,China National Knowledge Infrastructure(CNKI),Wanfang Database and the Chinese Science and Technology Journal Database(VIP)were searched from inception to September 20,2020 to collect relevant randomized controlled trials(RCTs)comparing SZL with other nootropic drugs for AD.The primary clinical outcomes were scores of the Mini Mental State Examination(MMSE)and the Activities of Daily Living(ADL)during treatment.The secondary outcomes of our study included other neuropsychological scale scores including Rapid Verbal Retrieve(RVR),Digit Span(DS),Fuld Object-Memory Evaluation(FOM)and adverse events or reactions.Two authors searched and screened the literature independently,then extracted the data and evaluated the methodological quality by using the handbook of Cochrane Collaboration,and analyzed the data via the Review Manager 5.3 software.Results:In total,we included four studies,covering 217 participants.All studies were in a low methodological quality.The result of MMSE score,ADL score,RVR score,DS score and FOM score in the meta-analysis showed that no statistically significant difference(P>0.05)between the treatment groups and control groups,and the statistical heterogeneity of all meta-analyses was small(I2<50%).SZL was indicated no better than other nootropic drugs.Among the included studies,no study described adverse events.Conclusions:Considering the low quality of the included trials and the different levels of AD patients,we are unable to come to any conclusion about the efficacy and safety of SZL compared with other nootropic drugs.Moreover,we still need rigorously designed,multi-center,large-scale trials to further confirm the efficacy and safety of SZL.展开更多
This article analyzes the connotation of Shen in Confucianism and Taoism and Shen in Nei Jing by using the method of literature review,and it raises:the two are closely related.First of all,on the basis of the meaning...This article analyzes the connotation of Shen in Confucianism and Taoism and Shen in Nei Jing by using the method of literature review,and it raises:the two are closely related.First of all,on the basis of the meaning of"god"before the pre-Qin period,the study of Confucianism and Taoism enriches the connotation of Shen,it extracts many implications,such as"magic","unpredictable","mental spirits","Xin Shen","intelligence","laws"etc.,endowing Shen with philosophy meanings.Secondly,Nei Jing introduces Shen with philosophy meanings into the field of Chinese medicine to explain phenomena related to life,at the same time,it confirms the reality of Shen and constructs a complete Shen theory system.展开更多
中医实体识别是智能医学领域一项重要的基础任务,针对通用的实体识别模型忽略了中医实体之间强关联性的问题,文章提出了一种特征融合方法。以预训练BERT(Bidirectional Encoder Representation from Transformers)模型为基础,对输入信...中医实体识别是智能医学领域一项重要的基础任务,针对通用的实体识别模型忽略了中医实体之间强关联性的问题,文章提出了一种特征融合方法。以预训练BERT(Bidirectional Encoder Representation from Transformers)模型为基础,对输入信息进行特征提取后,进一步对每个实体特征与语句特征进行融合,以获得更丰富的上下文特征,进而增强模型对中医实体的提取能力。使用临床数据开展实验证明,该方法与其他模型相比,在草药和症状实体识别任务上获得了更高的F1分数,分别为94.90%和83.92%,能更准确有效地提取医案中的实体。展开更多
文摘This article will present the result of 35 years of studies andresearch initiated by two teachers:Professor Leung KokYuen(China)and Professor Truong Thin(Vietnam).This article will briefly introduce the systems of traditional Chinese medicine,such as Jing(精),Xue(血),Qi(气),Shen(神)and Jin Ye(津液)compared with various systems in modern medicine.
基金This work was supported by the second batch of the“Ten thousand plan”,a national high-level talent special support plan(W02020052).
文摘Objective:To evaluate the efficacy and safety of Shen Zhi Ling oral liquid(SZL)alone or combined with basic treatment in treating Alzheimer's Disease(AD).Methods:Databases including PubMed,the Cochrane Library,Embase,Web of science,China National Knowledge Infrastructure(CNKI),Wanfang Database and the Chinese Science and Technology Journal Database(VIP)were searched from inception to September 20,2020 to collect relevant randomized controlled trials(RCTs)comparing SZL with other nootropic drugs for AD.The primary clinical outcomes were scores of the Mini Mental State Examination(MMSE)and the Activities of Daily Living(ADL)during treatment.The secondary outcomes of our study included other neuropsychological scale scores including Rapid Verbal Retrieve(RVR),Digit Span(DS),Fuld Object-Memory Evaluation(FOM)and adverse events or reactions.Two authors searched and screened the literature independently,then extracted the data and evaluated the methodological quality by using the handbook of Cochrane Collaboration,and analyzed the data via the Review Manager 5.3 software.Results:In total,we included four studies,covering 217 participants.All studies were in a low methodological quality.The result of MMSE score,ADL score,RVR score,DS score and FOM score in the meta-analysis showed that no statistically significant difference(P>0.05)between the treatment groups and control groups,and the statistical heterogeneity of all meta-analyses was small(I2<50%).SZL was indicated no better than other nootropic drugs.Among the included studies,no study described adverse events.Conclusions:Considering the low quality of the included trials and the different levels of AD patients,we are unable to come to any conclusion about the efficacy and safety of SZL compared with other nootropic drugs.Moreover,we still need rigorously designed,multi-center,large-scale trials to further confirm the efficacy and safety of SZL.
文摘This article analyzes the connotation of Shen in Confucianism and Taoism and Shen in Nei Jing by using the method of literature review,and it raises:the two are closely related.First of all,on the basis of the meaning of"god"before the pre-Qin period,the study of Confucianism and Taoism enriches the connotation of Shen,it extracts many implications,such as"magic","unpredictable","mental spirits","Xin Shen","intelligence","laws"etc.,endowing Shen with philosophy meanings.Secondly,Nei Jing introduces Shen with philosophy meanings into the field of Chinese medicine to explain phenomena related to life,at the same time,it confirms the reality of Shen and constructs a complete Shen theory system.
文摘中医实体识别是智能医学领域一项重要的基础任务,针对通用的实体识别模型忽略了中医实体之间强关联性的问题,文章提出了一种特征融合方法。以预训练BERT(Bidirectional Encoder Representation from Transformers)模型为基础,对输入信息进行特征提取后,进一步对每个实体特征与语句特征进行融合,以获得更丰富的上下文特征,进而增强模型对中医实体的提取能力。使用临床数据开展实验证明,该方法与其他模型相比,在草药和症状实体识别任务上获得了更高的F1分数,分别为94.90%和83.92%,能更准确有效地提取医案中的实体。
