The photoisomerization of trans-stilbene was studied in the water in oil (W/O) micro-emulsion formed by SDS (sodium dodecyl sulfate), n-C5H11OH (1-pentanol) and H2O. The experimental results show that after 2-minute U...The photoisomerization of trans-stilbene was studied in the water in oil (W/O) micro-emulsion formed by SDS (sodium dodecyl sulfate), n-C5H11OH (1-pentanol) and H2O. The experimental results show that after 2-minute UV-irradiation, the yield of cw-stilbene is higher in W/O microemulsion than in homogeneous solvent-n-C5H11OH.展开更多
A practical method to stereospecifically synthesize trans-stilbenes was developed via the one-pot benzylation-dehydration reaction of aromatic aldehydes with benzyltrimethylsilane （BTMS）, which was driven by tetrabu...A practical method to stereospecifically synthesize trans-stilbenes was developed via the one-pot benzylation-dehydration reaction of aromatic aldehydes with benzyltrimethylsilane （BTMS）, which was driven by tetrabu- tylammonium fluoride （TBAF） in THF. At the same time a plausible description of the whole process was proposed and the effects of substituted groups on the reaction were investigated. Also this method was employed to synthesize three precursors of natural products with excellent yields, which demonstrated that this method is much efficient and practical in the synthesis of some natural products.展开更多
A series of novel coumarin-stilbenes hybrids called 3-arylcoumarins were synthesized via Perkin reaction and evaluated as potential antitumor agents.The results showed that some compounds exhibited in vitro activity a...A series of novel coumarin-stilbenes hybrids called 3-arylcoumarins were synthesized via Perkin reaction and evaluated as potential antitumor agents.The results showed that some compounds exhibited in vitro activity against KB,KV,MCF-7,MCF-7/ ADR cell lines to some extent.Compound 3a showed remarkable effect against KB tumor cells with an IC50 value of 5.18μmol/L.展开更多
文摘The photoisomerization of trans-stilbene was studied in the water in oil (W/O) micro-emulsion formed by SDS (sodium dodecyl sulfate), n-C5H11OH (1-pentanol) and H2O. The experimental results show that after 2-minute UV-irradiation, the yield of cw-stilbene is higher in W/O microemulsion than in homogeneous solvent-n-C5H11OH.
文摘A practical method to stereospecifically synthesize trans-stilbenes was developed via the one-pot benzylation-dehydration reaction of aromatic aldehydes with benzyltrimethylsilane （BTMS）, which was driven by tetrabu- tylammonium fluoride （TBAF） in THF. At the same time a plausible description of the whole process was proposed and the effects of substituted groups on the reaction were investigated. Also this method was employed to synthesize three precursors of natural products with excellent yields, which demonstrated that this method is much efficient and practical in the synthesis of some natural products.
基金National Key Technology R&D Program,Science and Technology Program of Guangdong Province and Strategic Cooperation Program between Guangdong Province and Chinese Academy of Sciences,PR China(Nos. 2007BAD82B02,2006B35604002,and 2009B091300125) for financial support
文摘A series of novel coumarin-stilbenes hybrids called 3-arylcoumarins were synthesized via Perkin reaction and evaluated as potential antitumor agents.The results showed that some compounds exhibited in vitro activity against KB,KV,MCF-7,MCF-7/ ADR cell lines to some extent.Compound 3a showed remarkable effect against KB tumor cells with an IC50 value of 5.18μmol/L.
