This white paper explores three popular development methodologies for network softwarization: DevOps, NetOps, and Verification. The paper compares and contrasts the strengths and weaknesses of each approach and provid...This white paper explores three popular development methodologies for network softwarization: DevOps, NetOps, and Verification. The paper compares and contrasts the strengths and weaknesses of each approach and provides recommendations for organizations looking to adopt network softwarization.展开更多
The philosophical foundation of the mainstream neoclassical economics is empirical philosophy.The controversies of economic methodology over inductive and deductive methods,over verificationistic and falsificationisti...The philosophical foundation of the mainstream neoclassical economics is empirical philosophy.The controversies of economic methodology over inductive and deductive methods,over verificationistic and falsificationistic approaches,and over positive and normative analyses in the evolution of economics are associated with those in the philosophy of science.The evolution of philosophy of science suggests that the above-mentioned pairs of economic methodologies should be appropriately combined when used in economics.It is not sensible to overemphasize either one inside each pair of economic methodologies.展开更多
Interferometry with computer-generated holograms(CGHs)is a unique solution for the highly accurate testing of large-aperture aspheric mirrors.However,no direct testing method for quantifying the measurement accuracy o...Interferometry with computer-generated holograms(CGHs)is a unique solution for the highly accurate testing of large-aperture aspheric mirrors.However,no direct testing method for quantifying the measurement accuracy of CGHs has been developed.In this study,we developed a methodology for verifying CGH accuracy based on an element that is functionally equivalent to a large-aperture mirror in terms of accuracy verification.The equivalent element decreased the aperture by one or higher orders of magnitude,implying that the mirror could be replaced by a non-CGH technology in a comparison test.In this study,a 281 mm diamond-turned mirror was fabricated as the equivalent element of a 3.5 m aspheric mirror and measured using CGH and LUPHOScan profilometers.Surface error composition and root-mean-square(RMS)density analyses were performed.The methodology verification accuracy of the CGH was 4 nm(RMS)in the low-to mid-frequency bands,with a measured surface accuracy of approximately 10 nm(RMS).This methodology provides a feasible solution for CGH accuracy verification,ensuring high-accuracy and reliable testing of large-aperture aspheric mirrors.展开更多
目的对胶乳增强免疫比浊神经元特异性烯醇化酶(neuron-specific enolase,NSE)试剂盒进行性能验证。方法按照CNAS-GL037:2019《临床化学定量检验程序性能验证指南》、WS/T492-2016《临床检测定量测定项目精密度与正确度性能验证》并结合...目的对胶乳增强免疫比浊神经元特异性烯醇化酶(neuron-specific enolase,NSE)试剂盒进行性能验证。方法按照CNAS-GL037:2019《临床化学定量检验程序性能验证指南》、WS/T492-2016《临床检测定量测定项目精密度与正确度性能验证》并结合试验工作,重新设计了检验方法,在贝克曼库尔特AU5800全自动生化分析对北京九强金斯尔NSE胶乳增强免疫比浊法试剂盒的正确度、精密度、线性范围、可报告范围和生物参考区间等性能进行验证和评估,并与对应罗氏电化学发光法试剂盒进行方法学比对。测试结果与厂家所给出的产品分析性能以及美国国家卫生委员会临床检测中心(National Center for Clinical Laboratories,NCCL)的相关指标进行了对比。结果5个水平的正确度偏倚分别为1.74%、-1.42%、-0.88%、-3.09%和-0.90%;2个水平的批内及批间精密度的变异系数(coefficient of variation,CV)分别为1.85%和0.88%(判断标准CV<7.5%),4.99%和3.34%(判断标准CV<10%);线性范围(3.5~148.1ng/mL)验证回归系数a值为0.9894,R2=0.9978;最大稀释倍数为8倍,临床可报告上限为1165.2ng/mL;厂家提供的生物参考区间为0~16.3ng/L,符合率R为100%,各性能均通过验证。此外,与罗氏电化学发光试剂盒进行方法学比对,其相关性分析结果为:两种方法的相关性(R2=0.989)、一致性(CCC=0.984)均较好,在临床判定效果上同Roche的电化学发光试剂盒相比,免疫增强比浊方法阳性符合率为95.74%,阴性符合率为96.23%,两者测定值接近,相关系数达0.9894。结论基于全自动生化分析平台测定的NSE胶乳增强免疫比浊试剂盒,各性能均可以较好地满足临床使用要求,且与电化学发光法检测结果一致性较好,有望进一步推进NSE国产体外诊断试剂盒的临床应用。展开更多
建立基于液相色谱-串联质谱(liquid chromatography-tandem mass spectrometry,LC-MS/MS)测定湘派卤汁中10种真菌毒素的方法,并进行方法学验证及实际样品检测。样品中同步加入同位素内标经V(乙腈)∶V(水)∶V(乙酸)=84∶15∶1提取液超声...建立基于液相色谱-串联质谱(liquid chromatography-tandem mass spectrometry,LC-MS/MS)测定湘派卤汁中10种真菌毒素的方法,并进行方法学验证及实际样品检测。样品中同步加入同位素内标经V(乙腈)∶V(水)∶V(乙酸)=84∶15∶1提取液超声波处理、离心提取后,取上清液和水稀释净化,甲醇-水溶液为流动相梯度洗脱,采用电喷雾正负离子的多反应离子监测模式,利用同位素内标定量法进行定性和定量分析。结果表明,10种真菌毒素在10~200μg/L线性范围内线性关系良好(R^(2)>0.9985),检出限和定量限分别为0.1~13.0μg/kg和0.3~40.0μg/kg。10种真菌毒素的3个浓度水平加标回收率为78.6%~107.3%,相对标准偏差为2.2%~14.0%,符合方法学要求。该方法操作简便,回收率、灵敏度、检出限等均满足方法学要求,适用于卤汁中10种真菌毒素的测定。展开更多
文摘This white paper explores three popular development methodologies for network softwarization: DevOps, NetOps, and Verification. The paper compares and contrasts the strengths and weaknesses of each approach and provides recommendations for organizations looking to adopt network softwarization.
基金the Research Project titled“The Role of the Global Development Initiative in Promoting Balanced,Coordinated and Inclusive Global Development”(ID:3162022ZYE03)and funded by the Basic Research Funds for Centrally Administered Institutions of Tertiary Education.
文摘The philosophical foundation of the mainstream neoclassical economics is empirical philosophy.The controversies of economic methodology over inductive and deductive methods,over verificationistic and falsificationistic approaches,and over positive and normative analyses in the evolution of economics are associated with those in the philosophy of science.The evolution of philosophy of science suggests that the above-mentioned pairs of economic methodologies should be appropriately combined when used in economics.It is not sensible to overemphasize either one inside each pair of economic methodologies.
基金supported by the National Natural Science Foundation of China(62127901,52375471,and 62305333)supported by the National Key Research and Development Program(2022YFB3403405)+2 种基金Youth Innovation Promotion Association of the Chinese Academy of Sciences(2019221)Young Elite Scientists Sponsorship Program of CAST(2022QNRC001)Young Elite Scientists Sponsorship Program of Jilin Province(QT202222).
文摘Interferometry with computer-generated holograms(CGHs)is a unique solution for the highly accurate testing of large-aperture aspheric mirrors.However,no direct testing method for quantifying the measurement accuracy of CGHs has been developed.In this study,we developed a methodology for verifying CGH accuracy based on an element that is functionally equivalent to a large-aperture mirror in terms of accuracy verification.The equivalent element decreased the aperture by one or higher orders of magnitude,implying that the mirror could be replaced by a non-CGH technology in a comparison test.In this study,a 281 mm diamond-turned mirror was fabricated as the equivalent element of a 3.5 m aspheric mirror and measured using CGH and LUPHOScan profilometers.Surface error composition and root-mean-square(RMS)density analyses were performed.The methodology verification accuracy of the CGH was 4 nm(RMS)in the low-to mid-frequency bands,with a measured surface accuracy of approximately 10 nm(RMS).This methodology provides a feasible solution for CGH accuracy verification,ensuring high-accuracy and reliable testing of large-aperture aspheric mirrors.
文摘目的对胶乳增强免疫比浊神经元特异性烯醇化酶(neuron-specific enolase,NSE)试剂盒进行性能验证。方法按照CNAS-GL037:2019《临床化学定量检验程序性能验证指南》、WS/T492-2016《临床检测定量测定项目精密度与正确度性能验证》并结合试验工作,重新设计了检验方法,在贝克曼库尔特AU5800全自动生化分析对北京九强金斯尔NSE胶乳增强免疫比浊法试剂盒的正确度、精密度、线性范围、可报告范围和生物参考区间等性能进行验证和评估,并与对应罗氏电化学发光法试剂盒进行方法学比对。测试结果与厂家所给出的产品分析性能以及美国国家卫生委员会临床检测中心(National Center for Clinical Laboratories,NCCL)的相关指标进行了对比。结果5个水平的正确度偏倚分别为1.74%、-1.42%、-0.88%、-3.09%和-0.90%;2个水平的批内及批间精密度的变异系数(coefficient of variation,CV)分别为1.85%和0.88%(判断标准CV<7.5%),4.99%和3.34%(判断标准CV<10%);线性范围(3.5~148.1ng/mL)验证回归系数a值为0.9894,R2=0.9978;最大稀释倍数为8倍,临床可报告上限为1165.2ng/mL;厂家提供的生物参考区间为0~16.3ng/L,符合率R为100%,各性能均通过验证。此外,与罗氏电化学发光试剂盒进行方法学比对,其相关性分析结果为:两种方法的相关性(R2=0.989)、一致性(CCC=0.984)均较好,在临床判定效果上同Roche的电化学发光试剂盒相比,免疫增强比浊方法阳性符合率为95.74%,阴性符合率为96.23%,两者测定值接近,相关系数达0.9894。结论基于全自动生化分析平台测定的NSE胶乳增强免疫比浊试剂盒,各性能均可以较好地满足临床使用要求,且与电化学发光法检测结果一致性较好,有望进一步推进NSE国产体外诊断试剂盒的临床应用。
文摘建立基于液相色谱-串联质谱(liquid chromatography-tandem mass spectrometry,LC-MS/MS)测定湘派卤汁中10种真菌毒素的方法,并进行方法学验证及实际样品检测。样品中同步加入同位素内标经V(乙腈)∶V(水)∶V(乙酸)=84∶15∶1提取液超声波处理、离心提取后,取上清液和水稀释净化,甲醇-水溶液为流动相梯度洗脱,采用电喷雾正负离子的多反应离子监测模式,利用同位素内标定量法进行定性和定量分析。结果表明,10种真菌毒素在10~200μg/L线性范围内线性关系良好(R^(2)>0.9985),检出限和定量限分别为0.1~13.0μg/kg和0.3~40.0μg/kg。10种真菌毒素的3个浓度水平加标回收率为78.6%~107.3%,相对标准偏差为2.2%~14.0%,符合方法学要求。该方法操作简便,回收率、灵敏度、检出限等均满足方法学要求,适用于卤汁中10种真菌毒素的测定。
