Abstract: With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture (EA) and transcutan...Abstract: With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS), become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of ENTEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/rEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome (PCOS), pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligosperrnia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.展开更多
目的:采用Meta分析评价经皮穴位电刺激(TEAS)在预防老年患者术后谵妄(POD)中的效果。方法:系统检索Pubmed、Cochrane Library、Web of Science、Embase、中国知网、万方和维普等数据库,收集建库至2023年8月30日关于TEAS治疗老年手术患...目的:采用Meta分析评价经皮穴位电刺激(TEAS)在预防老年患者术后谵妄(POD)中的效果。方法:系统检索Pubmed、Cochrane Library、Web of Science、Embase、中国知网、万方和维普等数据库,收集建库至2023年8月30日关于TEAS治疗老年手术患者的随机对照试验(RCTs),采用RevMan 5.3软件进行Meta分析。结果:本研究共纳入22篇文献,共2645例研究对象。Meta分析结果显示,TEAS能降低老年患者术后POD的发生率(RR=0.46,95%CI:0.38,0.56),接受骨科手术(RR=0.50,95%CI:0.40,0.63)、腹部手术(RR=0.41,95%CI:0.25,0.65)及肿瘤手术(RR=0.33,95%CI:0.19,0.57)的老年患者术后POD的发生率均显著下降(均P<0.001);TEAS术中全程(RR=0.39,95%CI:0.29,0.53)或延续到术后(RR=0.52,95%CI:0.36,0.75)可明显降低老年患者术后POD发生率。结论:TEAS可有效降低行骨科、腹部及肿瘤等手术的老年患者术后POD的发生,TEAS术中全程使用或延续到术后均能有效抑制老年患者术后POD的发生,值得临床推广应用。展开更多
目的使用独立分量分析方法探索督脉穴位经皮电刺激对脑功能的影响。方法使用1.5T GE Signa Excite核磁成像仪对一位女性脑外伤患者进行BOLD成像。采用组块设计,静息期与刺激期交替,组块长度均为30 s。数据处理采用GIFT、SPM5和MRIcro软...目的使用独立分量分析方法探索督脉穴位经皮电刺激对脑功能的影响。方法使用1.5T GE Signa Excite核磁成像仪对一位女性脑外伤患者进行BOLD成像。采用组块设计,静息期与刺激期交替,组块长度均为30 s。数据处理采用GIFT、SPM5和MRIcro软件进行,并将独立分量分析与SPM软件处理的结果进行比较。结果采用GIFT中的扩展Infomax算法进行独立分量分析,显示有13个独立成分,每一独立成分包含一空间图和相应的时间变化曲线。任务相关性独立成分的空间激活图与SPM5的分析结果类似,但并不完全相同。此外,这些任务相关性独立成分的时间曲线与SPM所用的经典血流动力相应函数模型的形状并不一致。结论在使用模型依赖的数据分析方法如SPM之前,可以使用独立分量分析探索fMRI数据并获得先验知识。展开更多
基金Project supported by the Special Research Fund for the Public Welfare Industry of Health of China(No.201302013)
文摘Abstract: With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS), become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of ENTEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/rEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome (PCOS), pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligosperrnia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.
文摘目的:采用Meta分析评价经皮穴位电刺激(TEAS)在预防老年患者术后谵妄(POD)中的效果。方法:系统检索Pubmed、Cochrane Library、Web of Science、Embase、中国知网、万方和维普等数据库,收集建库至2023年8月30日关于TEAS治疗老年手术患者的随机对照试验(RCTs),采用RevMan 5.3软件进行Meta分析。结果:本研究共纳入22篇文献,共2645例研究对象。Meta分析结果显示,TEAS能降低老年患者术后POD的发生率(RR=0.46,95%CI:0.38,0.56),接受骨科手术(RR=0.50,95%CI:0.40,0.63)、腹部手术(RR=0.41,95%CI:0.25,0.65)及肿瘤手术(RR=0.33,95%CI:0.19,0.57)的老年患者术后POD的发生率均显著下降(均P<0.001);TEAS术中全程(RR=0.39,95%CI:0.29,0.53)或延续到术后(RR=0.52,95%CI:0.36,0.75)可明显降低老年患者术后POD发生率。结论:TEAS可有效降低行骨科、腹部及肿瘤等手术的老年患者术后POD的发生,TEAS术中全程使用或延续到术后均能有效抑制老年患者术后POD的发生,值得临床推广应用。
文摘目的使用独立分量分析方法探索督脉穴位经皮电刺激对脑功能的影响。方法使用1.5T GE Signa Excite核磁成像仪对一位女性脑外伤患者进行BOLD成像。采用组块设计,静息期与刺激期交替,组块长度均为30 s。数据处理采用GIFT、SPM5和MRIcro软件进行,并将独立分量分析与SPM软件处理的结果进行比较。结果采用GIFT中的扩展Infomax算法进行独立分量分析,显示有13个独立成分,每一独立成分包含一空间图和相应的时间变化曲线。任务相关性独立成分的空间激活图与SPM5的分析结果类似,但并不完全相同。此外,这些任务相关性独立成分的时间曲线与SPM所用的经典血流动力相应函数模型的形状并不一致。结论在使用模型依赖的数据分析方法如SPM之前,可以使用独立分量分析探索fMRI数据并获得先验知识。