Background The evaluation of retinal image quality in cataract eyes has gained importance and the clinical modulation transfer functions （MTF） can obtained by aberrometer and double pass （DP） system. This study ai...Background The evaluation of retinal image quality in cataract eyes has gained importance and the clinical modulation transfer functions （MTF） can obtained by aberrometer and double pass （DP） system. This study aimed to compare MTF derived from a ray tracing aberrometer and a DP system in early cataractous and normal eyes. Methods There were 128 subjects with 61 control eyes and 67 eyes with early cataract defined according to the Lens Opacities Classification System II1. A laser ray-tracing wavefront aberrometer （iTrace） and a double pass （DP） system （OQAS） assessed ocular MTF for 6.0 mm pupil diameters following dilation. Areas under the MTF （AUMTF） and their correlations were analyzed. Stepwise multiple regression analysis assessed factors affecting the differences between iTrace- and OQAS-derived AUMTF for the early cataract group. Results For both early cataract and control groups, iTrace-derived MTFs were higher than OQAS-derived MTFs across a range of spatial frequencies （P 〈0.01）. No significant difference between the two groups occurred for iTrace-derived AUMTF, but the early cataract group had significantly smaller OQAS-derived AUMTF than did the control group （P 〈0.01）. AUMTF determined from both the techniques demonstrated significant correlations with nuclear opacities, higher-order aberrations （HOAs）, visual acuity, and contrast sensitivity functions, while the OQAS-derived AUMTF also demonstrated significant correlations with age and cortical opacity grade. The factors significantly affecting the difference between iTrace and OQAS AUMTF were root-mean-squared HOAs （standardized beta coefficient=-0.63, P 〈0.01） and age （standardized beta coefficient=0.26, P 〈0.01）. Conclusions MTFs determined from a iTrace and a DP system （OQAS） differ significantly in early cataractous and normal subjects. Correlations with visual performance were higher for the DP system. OQAS-derived MTF may be useful as an indicator of visual performance in early cataract eyes.展开更多
Fluctuation of pump power is one of the major sources of temporal and intensity noise in femtosecond fiber lasers.In this work,the transfer functions between the relative intensity noise(RIN)of the pump laser diode(LD...Fluctuation of pump power is one of the major sources of temporal and intensity noise in femtosecond fiber lasers.In this work,the transfer functions between the relative intensity noise(RIN)of the pump laser diode(LD)and the output RIN,between the RIN of the pump LD and timing jitter of femtosecond fiber lasers are systematically studied.It is demonstrated,for the first time to our knowledge,that the amplitude of the pump RIN transfer function can be effectively decreased by an intra-cavity narrow band-pass filter.In particular,for normal-dispersion lasers,the 3-d B bandwidth of the transfer function can also be narrowed by two-thirds,with a steeper falling edge.Furthermore,with the narrow band-pass filtering,the transfer function is almost independent of the net intra-cavity dispersion due to amplifier similariton formation.The proposed scheme can effectively isolate the pump-induced noise without the need of complex active pump LD control and intra-cavity dispersion management,thus providing an easy way for practical high-power,high-stability femtosecond fiber laser design and related high-precision applications outside the laboratory.展开更多
文摘Background The evaluation of retinal image quality in cataract eyes has gained importance and the clinical modulation transfer functions （MTF） can obtained by aberrometer and double pass （DP） system. This study aimed to compare MTF derived from a ray tracing aberrometer and a DP system in early cataractous and normal eyes. Methods There were 128 subjects with 61 control eyes and 67 eyes with early cataract defined according to the Lens Opacities Classification System II1. A laser ray-tracing wavefront aberrometer （iTrace） and a double pass （DP） system （OQAS） assessed ocular MTF for 6.0 mm pupil diameters following dilation. Areas under the MTF （AUMTF） and their correlations were analyzed. Stepwise multiple regression analysis assessed factors affecting the differences between iTrace- and OQAS-derived AUMTF for the early cataract group. Results For both early cataract and control groups, iTrace-derived MTFs were higher than OQAS-derived MTFs across a range of spatial frequencies （P 〈0.01）. No significant difference between the two groups occurred for iTrace-derived AUMTF, but the early cataract group had significantly smaller OQAS-derived AUMTF than did the control group （P 〈0.01）. AUMTF determined from both the techniques demonstrated significant correlations with nuclear opacities, higher-order aberrations （HOAs）, visual acuity, and contrast sensitivity functions, while the OQAS-derived AUMTF also demonstrated significant correlations with age and cortical opacity grade. The factors significantly affecting the difference between iTrace and OQAS AUMTF were root-mean-squared HOAs （standardized beta coefficient=-0.63, P 〈0.01） and age （standardized beta coefficient=0.26, P 〈0.01）. Conclusions MTFs determined from a iTrace and a DP system （OQAS） differ significantly in early cataractous and normal subjects. Correlations with visual performance were higher for the DP system. OQAS-derived MTF may be useful as an indicator of visual performance in early cataract eyes.
基金funded by the National Science and Technology Innovation Special Zone Program of ChinaIndependent Innovation Project of China Academy of Space Technology+1 种基金Science and Technology Innovation Research and Development Project of China Aerospace Science and Technology CorporationNational Natural Science Foundation of China (No. 61675150)
文摘Fluctuation of pump power is one of the major sources of temporal and intensity noise in femtosecond fiber lasers.In this work,the transfer functions between the relative intensity noise(RIN)of the pump laser diode(LD)and the output RIN,between the RIN of the pump LD and timing jitter of femtosecond fiber lasers are systematically studied.It is demonstrated,for the first time to our knowledge,that the amplitude of the pump RIN transfer function can be effectively decreased by an intra-cavity narrow band-pass filter.In particular,for normal-dispersion lasers,the 3-d B bandwidth of the transfer function can also be narrowed by two-thirds,with a steeper falling edge.Furthermore,with the narrow band-pass filtering,the transfer function is almost independent of the net intra-cavity dispersion due to amplifier similariton formation.The proposed scheme can effectively isolate the pump-induced noise without the need of complex active pump LD control and intra-cavity dispersion management,thus providing an easy way for practical high-power,high-stability femtosecond fiber laser design and related high-precision applications outside the laboratory.
