[Objectives]To observe the clinical efficacy of Modified Huan'gan Lipi Decoction combined with acupuncture in the treatment of spleen deficiency and liver hyperactivity type tic disorders(TD).[Methods]Sixty patien...[Objectives]To observe the clinical efficacy of Modified Huan'gan Lipi Decoction combined with acupuncture in the treatment of spleen deficiency and liver hyperactivity type tic disorders(TD).[Methods]Sixty patients with spleen deficiency and liver hyperactivity type TD were randomly divided into a treatment group of 40 cases and a control group of 20 cases.The treatment group received Modified Huan'gan Lipi Decoction combined with acupuncture,and the control group received Haloperidol Tablets.After 4 weeks of treatment,the Yale Global Tic Severity Scale(YGTSS)score,the total score of TCM syndrome and the clinical efficacy were compared between the two groups before and after treatment.[Results]After treatment,the total effective rate of 87.5%in the treatment group was higher than 80.0%in the control group(P>0.05);the total score of YGTSS and the total score of TCM syndromes in the two groups were compared within groups,P﹤0.01;between groups,P﹤0.01.The recurrence rates of the treatment group and the control group were 11.1%and 71.4%,respectively.The difference between the two groups was statistically significant(P﹤0.01).[Conclusions]Modified Huan'gan Lipi Decoction combined with acupuncture in the treatment of spleen deficiency and liver hyperactivity type TD can significantly improve the patient's tic symptoms,and its long-term efficacy is stable.展开更多
目的:基于CiteSpace对儿童抽动障碍国内外相关文献进行可视化分析,总结发文现状、研究热点和发展趋势。方法:通过对2002年1月至2022年7月发表在Web of Science和中国知网数据库的儿童抽动障碍相关文献进行检索并筛选,利用CiteSpace软件...目的:基于CiteSpace对儿童抽动障碍国内外相关文献进行可视化分析,总结发文现状、研究热点和发展趋势。方法:通过对2002年1月至2022年7月发表在Web of Science和中国知网数据库的儿童抽动障碍相关文献进行检索并筛选,利用CiteSpace软件对纳入的文献进行作者、机构和国家共现分析,并对关键词共现、聚类和突现生成图谱,进行可视化分析。结果:共纳入英文文献1035篇、中文文献861篇,发文量分析显示,近20年国内外儿童抽动障碍相关研究的发文量均呈上升趋势,国外不同国家间的团队合作较紧密,相对集中于欧洲、北美洲等经济发达地区;国内研究机构以各地方中医药大学及其附属医院为主,形成了一定的研究团队。对关键词进行聚类分析,在图谱中形成了6中文文献聚类标签和10个英文文献聚类标签。对关键词进行共现分析,共得到10个中文共现关键词和10个英文共现关键词。对关键词进行突现分析,共得到20个中英文突现关键词。结论:相对于国外儿童抽动障碍研究的发展,我国应改善儿童抽动障碍学科发展模式,中西医并重,加强国内外学术交流,拓宽研究新思路。展开更多
基金Supported by Program of Ningxia Acupuncture and Moxibustion Clinical Medicine Research Center。
文摘[Objectives]To observe the clinical efficacy of Modified Huan'gan Lipi Decoction combined with acupuncture in the treatment of spleen deficiency and liver hyperactivity type tic disorders(TD).[Methods]Sixty patients with spleen deficiency and liver hyperactivity type TD were randomly divided into a treatment group of 40 cases and a control group of 20 cases.The treatment group received Modified Huan'gan Lipi Decoction combined with acupuncture,and the control group received Haloperidol Tablets.After 4 weeks of treatment,the Yale Global Tic Severity Scale(YGTSS)score,the total score of TCM syndrome and the clinical efficacy were compared between the two groups before and after treatment.[Results]After treatment,the total effective rate of 87.5%in the treatment group was higher than 80.0%in the control group(P>0.05);the total score of YGTSS and the total score of TCM syndromes in the two groups were compared within groups,P﹤0.01;between groups,P﹤0.01.The recurrence rates of the treatment group and the control group were 11.1%and 71.4%,respectively.The difference between the two groups was statistically significant(P﹤0.01).[Conclusions]Modified Huan'gan Lipi Decoction combined with acupuncture in the treatment of spleen deficiency and liver hyperactivity type TD can significantly improve the patient's tic symptoms,and its long-term efficacy is stable.
文摘目的:基于CiteSpace对儿童抽动障碍国内外相关文献进行可视化分析,总结发文现状、研究热点和发展趋势。方法:通过对2002年1月至2022年7月发表在Web of Science和中国知网数据库的儿童抽动障碍相关文献进行检索并筛选,利用CiteSpace软件对纳入的文献进行作者、机构和国家共现分析,并对关键词共现、聚类和突现生成图谱,进行可视化分析。结果:共纳入英文文献1035篇、中文文献861篇,发文量分析显示,近20年国内外儿童抽动障碍相关研究的发文量均呈上升趋势,国外不同国家间的团队合作较紧密,相对集中于欧洲、北美洲等经济发达地区;国内研究机构以各地方中医药大学及其附属医院为主,形成了一定的研究团队。对关键词进行聚类分析,在图谱中形成了6中文文献聚类标签和10个英文文献聚类标签。对关键词进行共现分析,共得到10个中文共现关键词和10个英文共现关键词。对关键词进行突现分析,共得到20个中英文突现关键词。结论:相对于国外儿童抽动障碍研究的发展,我国应改善儿童抽动障碍学科发展模式,中西医并重,加强国内外学术交流,拓宽研究新思路。