Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and...Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and vaporization of the prostate was performed in 55 male patients(260 specimens in total).In a standardized procedure,a bipolar resection loop was used for resection,and a bipolar button electrode was used for vaporization.Both electrodes were applied in each patient,either in the left or in the right lateral lobe.The depth of necrotic zones in the resected or vaporized tissue of each patient was measured in a standardized way by light microscopy.Results:The mean depth with standard deviation of thermal injury caused by the loop electrode was 0.0495±0.0274 mm.The vaporization electrode caused a mean thermal depth with standard deviation of 0.0477±0.0276 mm.The mean difference of necrosis zone depths between the two types of electrodes(PlasmaButtoneresection loop)was 0.0018 mm(p=0.691).Conclusion:For the first time,we present directly measured values of the absolute necrosis zone depth after application of plasma in the transurethral treatment of benign prostatic hyperplasia.The measured values were lower than in all other transurethral procedures.Standardized procedures of measurement and evaluation allow a statistically significant statement that the low necrosis depth in bipolar procedures is independent of the applied electrodes.展开更多
Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retro...Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retrospective observational case series.Methods:One hundred and twenty-one patients presenting with symptoms of bladder outflow obstruction after endo-urological intervention for BPH from February 2016 to March 2019 were evaluated.Among them,76 were eligible for this study and underwent reconstructive surgery.Preoperative and postoperative assessments were done with symptom scores,uroflowmetry,ultrasound for post-void residue,and urethrogram.Any intervention during follow-up was classed as a failure.The recurrence and 95%confidence interval for recurrence percentage were calculated.Results:The following five categories of patients were identified:Bulbo-membranous(33[43.4%]),navicular fossa(21[27.6%]),penile/peno-bulbar(8[10.5%]),bladder neck stenosis(6[7.9%]),and multiple locations(8[10.5%]).The average age was 69 years(range:60-84 years).Overall average symptom score,flow rate,and post-void residue changed from 21 to 7,6 mL/s to 19 mL/s,and 210 mL to 20 mL,respectively.The average follow-up was 34 months(range:12-58 months).Overall recurrence and complication rates were 10.5%and 9.2%,respectively.The recurrence in each category was seen in 3,1,2,1,and 1 patient,respectively.Overall 95% confidence interval for recurrence percentage was 4.66-19.69.Conclusion:Urethral stricture disease is a major long-term complication of endo-urological treatment of BPH.The bulbo-membranous strictures need continence preserving approach.Navicular fossa strictures require minimally invasive and cosmetic consideration.Peno-bulbar strictures require judicious use of grafts and flaps.Bladder neck stenosis in this cohort could be treated with endoscopic measures.Multiple locations need treatment based on their sites in single-stage as far as possible.展开更多
目的 :探讨经尿道前列腺电切术(transurethral resection of prostate,TURP)与经尿道双极等离子电切术(bipolar plasmakinetic resection of the prostate,PKRP)治疗良性前列腺增生(benign prostatic hyperplasia,BPH)疗效、并发症及安...目的 :探讨经尿道前列腺电切术(transurethral resection of prostate,TURP)与经尿道双极等离子电切术(bipolar plasmakinetic resection of the prostate,PKRP)治疗良性前列腺增生(benign prostatic hyperplasia,BPH)疗效、并发症及安全性差异。方法:收集2009年1月至2011年12月接受TURP和PKRP的BPH患者560例,其中TURP组210例,PKRP组350例,比较2组基线资料、疗效、并发症及安全性差异。结果:PKRP组与PKRP组比较,2组基线资料差异无统计学意义(P>0.05);PKRP组手术时间(t=8.046,P=0.000)、术中出血量(t=16.653,P=0.000)、留置尿管时间(t=7.701,P=0.000)均少于TURP组;TURP组术后较术前:国际前列腺症状评分(international prostate symptom score,IPSS)(t=62.092,P=0.000)、生活质量指数(quality of life,QOL)(t=72.355,P=0.000)、最大尿流率(maximum flow rate,Qmax)(t=73.993,P=0.000)均有改善,PKRP组术后较术前:IPSS(t=77.777,P=0.000)、QOL(t=82.038,P=0.000)、Qmax(t=89.860,P=0.000),均有明显改善,但2组间比较差异无统计学意义(P>0.05);TURP组前列腺电切综合征、血流动力学波动、术中大出血等13项发生率明显高于PKRP组(P<0.05)。结论:TURP和PKRP均为BPH的有效治疗手段。PKRP比较TURP,具有手术时间短、出血量少、并发症少、安全性更高等优点,但其长期疗效需进一步随访观察。展开更多
目的探讨经尿道超脉冲等离子体双极电切术(bipolar plasmakinetic superpulse transurethral resection of the prostate,PKSP+TURP)联合腔内剜除法治疗良性前列腺增生症(benign prostatic hyperplasia,BPH)的临床疗效。方法2006年1月～...目的探讨经尿道超脉冲等离子体双极电切术(bipolar plasmakinetic superpulse transurethral resection of the prostate,PKSP+TURP)联合腔内剜除法治疗良性前列腺增生症(benign prostatic hyperplasia,BPH)的临床疗效。方法2006年1月～2008年5月,采用英国Gyrus公司经尿道超脉冲等离子体双极电切与影像系统行PKSP+TURP联合腔内剜除法治疗BPH210例。腺体不大者,直接剜除后行PKSP+TURP;腺体较大、中叶增生明显者,先剜除中叶,行PKSP+TURP后剜除两侧叶,再行PKSP+TURP;腺体较大、两侧叶增生明显者,分别剜除两侧叶,同时行PKSP+TURP。结果手术时间20～130min,平均50.2min;术中出血量15～210ml,平均62.1ml。未发生电切综合征和膀胱穿孔等并发症。术后留置导尿管2～9d。210例随访2～30个月,IPSS由(23.8±4.7)分下降至(6.8±2.3)分(t=56.851,P=0.000),QOL由(4.3±0.8)分下降至(2.2±0.6)分(t=22.755,P=0.000),Qmax由(8.0±2.5)ml/s上升至(23.5±12.5)ml/s(t=-21.602,P=0.000),RU由(74.3±30.6)ml减少至(25.6±18.6)ml(t=11.315,P=0.000)。结论PKSP+TURP联合腔内剜除法治疗BPH,具有安全、并发症少、疗效确切等优点。展开更多
文摘Objectives:To compare the depth of thermal necrosis after use of bipolar resection and vaporization technique comparing intra-individually bipolar loop and bipolar button electrodes.Methods:Transurethral resection and vaporization of the prostate was performed in 55 male patients(260 specimens in total).In a standardized procedure,a bipolar resection loop was used for resection,and a bipolar button electrode was used for vaporization.Both electrodes were applied in each patient,either in the left or in the right lateral lobe.The depth of necrotic zones in the resected or vaporized tissue of each patient was measured in a standardized way by light microscopy.Results:The mean depth with standard deviation of thermal injury caused by the loop electrode was 0.0495±0.0274 mm.The vaporization electrode caused a mean thermal depth with standard deviation of 0.0477±0.0276 mm.The mean difference of necrosis zone depths between the two types of electrodes(PlasmaButtoneresection loop)was 0.0018 mm(p=0.691).Conclusion:For the first time,we present directly measured values of the absolute necrosis zone depth after application of plasma in the transurethral treatment of benign prostatic hyperplasia.The measured values were lower than in all other transurethral procedures.Standardized procedures of measurement and evaluation allow a statistically significant statement that the low necrosis depth in bipolar procedures is independent of the applied electrodes.
文摘Objective:Urethral stricture disease after endo-urological treatment of benign prostatic hyperplasia(BPH)is a sparsely described complication.We describe management of five categories of these strictures in this retrospective observational case series.Methods:One hundred and twenty-one patients presenting with symptoms of bladder outflow obstruction after endo-urological intervention for BPH from February 2016 to March 2019 were evaluated.Among them,76 were eligible for this study and underwent reconstructive surgery.Preoperative and postoperative assessments were done with symptom scores,uroflowmetry,ultrasound for post-void residue,and urethrogram.Any intervention during follow-up was classed as a failure.The recurrence and 95%confidence interval for recurrence percentage were calculated.Results:The following five categories of patients were identified:Bulbo-membranous(33[43.4%]),navicular fossa(21[27.6%]),penile/peno-bulbar(8[10.5%]),bladder neck stenosis(6[7.9%]),and multiple locations(8[10.5%]).The average age was 69 years(range:60-84 years).Overall average symptom score,flow rate,and post-void residue changed from 21 to 7,6 mL/s to 19 mL/s,and 210 mL to 20 mL,respectively.The average follow-up was 34 months(range:12-58 months).Overall recurrence and complication rates were 10.5%and 9.2%,respectively.The recurrence in each category was seen in 3,1,2,1,and 1 patient,respectively.Overall 95% confidence interval for recurrence percentage was 4.66-19.69.Conclusion:Urethral stricture disease is a major long-term complication of endo-urological treatment of BPH.The bulbo-membranous strictures need continence preserving approach.Navicular fossa strictures require minimally invasive and cosmetic consideration.Peno-bulbar strictures require judicious use of grafts and flaps.Bladder neck stenosis in this cohort could be treated with endoscopic measures.Multiple locations need treatment based on their sites in single-stage as far as possible.
文摘目的 :探讨经尿道前列腺电切术(transurethral resection of prostate,TURP)与经尿道双极等离子电切术(bipolar plasmakinetic resection of the prostate,PKRP)治疗良性前列腺增生(benign prostatic hyperplasia,BPH)疗效、并发症及安全性差异。方法:收集2009年1月至2011年12月接受TURP和PKRP的BPH患者560例,其中TURP组210例,PKRP组350例,比较2组基线资料、疗效、并发症及安全性差异。结果:PKRP组与PKRP组比较,2组基线资料差异无统计学意义(P>0.05);PKRP组手术时间(t=8.046,P=0.000)、术中出血量(t=16.653,P=0.000)、留置尿管时间(t=7.701,P=0.000)均少于TURP组;TURP组术后较术前:国际前列腺症状评分(international prostate symptom score,IPSS)(t=62.092,P=0.000)、生活质量指数(quality of life,QOL)(t=72.355,P=0.000)、最大尿流率(maximum flow rate,Qmax)(t=73.993,P=0.000)均有改善,PKRP组术后较术前:IPSS(t=77.777,P=0.000)、QOL(t=82.038,P=0.000)、Qmax(t=89.860,P=0.000),均有明显改善,但2组间比较差异无统计学意义(P>0.05);TURP组前列腺电切综合征、血流动力学波动、术中大出血等13项发生率明显高于PKRP组(P<0.05)。结论:TURP和PKRP均为BPH的有效治疗手段。PKRP比较TURP,具有手术时间短、出血量少、并发症少、安全性更高等优点,但其长期疗效需进一步随访观察。
文摘目的探讨经尿道超脉冲等离子体双极电切术(bipolar plasmakinetic superpulse transurethral resection of the prostate,PKSP+TURP)联合腔内剜除法治疗良性前列腺增生症(benign prostatic hyperplasia,BPH)的临床疗效。方法2006年1月～2008年5月,采用英国Gyrus公司经尿道超脉冲等离子体双极电切与影像系统行PKSP+TURP联合腔内剜除法治疗BPH210例。腺体不大者,直接剜除后行PKSP+TURP;腺体较大、中叶增生明显者,先剜除中叶,行PKSP+TURP后剜除两侧叶,再行PKSP+TURP;腺体较大、两侧叶增生明显者,分别剜除两侧叶,同时行PKSP+TURP。结果手术时间20～130min,平均50.2min;术中出血量15～210ml,平均62.1ml。未发生电切综合征和膀胱穿孔等并发症。术后留置导尿管2～9d。210例随访2～30个月,IPSS由(23.8±4.7)分下降至(6.8±2.3)分(t=56.851,P=0.000),QOL由(4.3±0.8)分下降至(2.2±0.6)分(t=22.755,P=0.000),Qmax由(8.0±2.5)ml/s上升至(23.5±12.5)ml/s(t=-21.602,P=0.000),RU由(74.3±30.6)ml减少至(25.6±18.6)ml(t=11.315,P=0.000)。结论PKSP+TURP联合腔内剜除法治疗BPH,具有安全、并发症少、疗效确切等优点。
