A new irlactane-type,namely irlactin K(1),and 22 tremulane-type sesquiterpenes including fourteen previously undescribed ones,namely irpexolactins A-N(2-15),and a known irlactane-type sesquiterpenoid,were isolated fro...A new irlactane-type,namely irlactin K(1),and 22 tremulane-type sesquiterpenes including fourteen previously undescribed ones,namely irpexolactins A-N(2-15),and a known irlactane-type sesquiterpenoid,were isolated from the fermentation broth of the medicinal fungus Irpex lacteus HFG1102.The structures of all the isolates were characterized by extensive spectroscopic methods,including 1D and 2D NMR and MS spectroscopic analysis.The absolute configurations of irlactin K and the known compound conocenol B(20)were established by single-crystal X-ray diffraction analysis.The vasorelaxant effects of irlactin K(1),irpexolactins A(2),C(4),K(12),and irlactam(22)were evaluated.展开更多
Two new tremulane sesquiterpenes coriolopsin A（1） and coriolopsin B（2）,together with two known ones conocenol C（3） and ceriponol E（4）,were isolated from the fermentation extract of endophytic fungus Coriolopsi...Two new tremulane sesquiterpenes coriolopsin A（1） and coriolopsin B（2）,together with two known ones conocenol C（3） and ceriponol E（4）,were isolated from the fermentation extract of endophytic fungus Coriolopsis sp.J5 from Ceriops tagal.The structures and absolute configuration of compounds 1 and 2 were determined based on HR-ESI-MS and spectroscopic data（IR,UV,1D,2D NMR and X-ray crystallographic analysis）.展开更多
Seven new tremulane-type sesquiterpenes （1 7） have been isolated from cultures of the basidiomycete Cono- cybe siliginea. Their structures and relative configurations were elucidated by extensive spectroscopic data ...Seven new tremulane-type sesquiterpenes （1 7） have been isolated from cultures of the basidiomycete Cono- cybe siliginea. Their structures and relative configurations were elucidated by extensive spectroscopic data （HSQC, HMBC, 1H-tH COSY, ROESY） and MS analysis.展开更多
基金supported by National Natural Science Foundation of China(Nos.81903512,21961142008).
文摘A new irlactane-type,namely irlactin K(1),and 22 tremulane-type sesquiterpenes including fourteen previously undescribed ones,namely irpexolactins A-N(2-15),and a known irlactane-type sesquiterpenoid,were isolated from the fermentation broth of the medicinal fungus Irpex lacteus HFG1102.The structures of all the isolates were characterized by extensive spectroscopic methods,including 1D and 2D NMR and MS spectroscopic analysis.The absolute configurations of irlactin K and the known compound conocenol B(20)were established by single-crystal X-ray diffraction analysis.The vasorelaxant effects of irlactin K(1),irpexolactins A(2),C(4),K(12),and irlactam(22)were evaluated.
基金financially supported by National Natural Science Foundation of China (Nos. 41406083, 41506096)National Nonprofit Institute Research Grant of CATAS-ITBB (No. ITBB2015ZY04, ITBB2015RC02)
文摘Two new tremulane sesquiterpenes coriolopsin A（1） and coriolopsin B（2）,together with two known ones conocenol C（3） and ceriponol E（4）,were isolated from the fermentation extract of endophytic fungus Coriolopsis sp.J5 from Ceriops tagal.The structures and absolute configuration of compounds 1 and 2 were determined based on HR-ESI-MS and spectroscopic data（IR,UV,1D,2D NMR and X-ray crystallographic analysis）.
文摘Seven new tremulane-type sesquiterpenes （1 7） have been isolated from cultures of the basidiomycete Cono- cybe siliginea. Their structures and relative configurations were elucidated by extensive spectroscopic data （HSQC, HMBC, 1H-tH COSY, ROESY） and MS analysis.
