A facile preparation of allylic trifluoromethyl thioethers was achieved by using a copper reagent. The reaction of （bpy）Cu（SCF3） with various allylic bromides afforded the desired trifluoromethylthiolation product...A facile preparation of allylic trifluoromethyl thioethers was achieved by using a copper reagent. The reaction of （bpy）Cu（SCF3） with various allylic bromides afforded the desired trifluoromethylthiolation products in good to excellent yields with high stereo- and regioselectivity. Common functional groups such as alkyl, alkoxy, trifluoromethyl, nitro, halides and geranyl are well tolerated.展开更多
基金Acknowledgement This work was supported by National Natural Science Foundation of China （No. 21072030）, Research Fund for the Doctoral Program of Higher Education of China （No. 20123514110003）, the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry （No. 2012-1707）, and Fuzhou University （Nos. 022318, 022494）.
文摘A facile preparation of allylic trifluoromethyl thioethers was achieved by using a copper reagent. The reaction of （bpy）Cu（SCF3） with various allylic bromides afforded the desired trifluoromethylthiolation products in good to excellent yields with high stereo- and regioselectivity. Common functional groups such as alkyl, alkoxy, trifluoromethyl, nitro, halides and geranyl are well tolerated.
