Jadomycin is an antibiotic that has shown activities against bacteria, yeasts and fungi as well as cytotoxic properties to cancer cells. Because of the wide range of its inhibitory actions, jadomycin shows promise as ...Jadomycin is an antibiotic that has shown activities against bacteria, yeasts and fungi as well as cytotoxic properties to cancer cells. Because of the wide range of its inhibitory actions, jadomycin shows promise as a novel antibiotic and cancer treatment drug. Streptomyces venezuelae are aerobic bacteria that produce jadomycin and the size of bacterial population can significantly affect the yield of jadomycin. Therefore, the bacterial population must be accurately measured in order to standardize the reproducibility of jadomycin production process. In this study, a dehydrogenase activity measurement test, using triphenyl tetrazolium chloride (TTC), was used to measure the dehydrogenase activity of Streptomyces venezuelae during growth in maltose-yeast extract-malt extract (MYM) broth. The aims were to evaluate the effectiveness of the test for measuring microbial growth and to study the effects of the test conditions (incubation time, incubation temperature and medium pH) on triphenyl formazan (TF) yield. The results showed that the TF yield was highly correlated to the optical density. The highest TF yield was observed at a pH of 6 at all incubation times and temperature. Lower TF yields were obtained at higher temperature (40 and 50oC) compared to those obtained at lower temperatures (22 and 30oC). The difference between the yields obtained at 22oC and 30oC were not significant. The differences between incubation time were also not significant. The recommended test conditions are an incubation time of 1 hour at a temperature of 30oC and a pH of 6 followed by three extractions using methanol.展开更多
The structures and electronic spectra of the derivatives of C60-P-2,4,6-triphenyl borazinc have been studied by using AM 1 method. The calculated results indicate that this kind of compounds has a lower energy differe...The structures and electronic spectra of the derivatives of C60-P-2,4,6-triphenyl borazinc have been studied by using AM 1 method. The calculated results indicate that this kind of compounds has a lower energy difference between HOMO and LUMO. It is found that the electron cloud on unoccupied frontier orbital mainly comes from the contribution of C60, while that on occupied frontier orbital mainly concentrates on the side chain. A long-lived charge-separated state may occur in the objective compounds.展开更多
ByBimolecular Nucleophilic Substitution, four new types of alkylene triphenyl double quaternary phosphonium salt were synthesized respectively by using triphenylphosphine, 1,3-dibromopropane, 1,6-dibromohexane,1,10-di...ByBimolecular Nucleophilic Substitution, four new types of alkylene triphenyl double quaternary phosphonium salt were synthesized respectively by using triphenylphosphine, 1,3-dibromopropane, 1,6-dibromohexane,1,10-dibromo- decane, 1,12-dibromododecane as raw materials and using DMAC as the solvent, under a certain temperature and reac- tion time. The productivity is 58% - 83%. The molecular structures of the products were characterized by IR, NMR and elemental analysis. The sterilizing effect of 1,6-hexylidene triphenyl double phosphonium bromide(HTDPB) and 1,12- dodecylidene triphenyl double phosphonium bromide(DoTDPB) was evaluated by using extinct dilution method.The experimental result shows that the sterilizing effect of DoTDPB is better than the effect of HTDPB under the same drug concentration and contact time. When the concentration of DoTDPB was 20 mg/L and the contact time was 0.5 h, the sterilizing rate of DoTDPB used to kill saprophytic bacteria (TGB), sulfate-reducing bacteria (SRB) and iron bacteria (IB) was 95.56%, 84% and 99.58% respectively.展开更多
The new tetracarbonyl - chromium-triphenyl phosphine complex was synthesized and characterized using ultraviolet（UV）-visible,Fourier transform infrared（FTIR）,and nuclear magnetic resonance（NMR） techniques.The ch...The new tetracarbonyl - chromium-triphenyl phosphine complex was synthesized and characterized using ultraviolet（UV）-visible,Fourier transform infrared（FTIR）,and nuclear magnetic resonance（NMR） techniques.The characterization results confirm the molecular structure of the new complex.The z-scan measurements were done by diode laser[continuous wave（CW）]to estimate the nonlinear optical parameter（X^3）.The results led to calculate three parameters：the groundstate cross sections（σ_g）,the excited-state cross sections（σ_（ex））,and thermo-optic coefficient of the new complex.This study indicated that our complex is a suitable for photonic applications.展开更多
Six triphenylmethane dyes viz., bromophenol blue, basic fuchsin, methyl violet, methyl green, ethyl violet and malachite green were studied for their decolorization by Fomitopsis feei. Among, basic fuchsin (98%) was m...Six triphenylmethane dyes viz., bromophenol blue, basic fuchsin, methyl violet, methyl green, ethyl violet and malachite green were studied for their decolorization by Fomitopsis feei. Among, basic fuchsin (98%) was maximum decolorized followed by bromophenol blue (96.8%). However, the rate of bromophenol blue decolorization was very fast. There was no correlation between the lignolytic activity and dye decolurization of the dyes. The highest laccase and lignin peroxidase activities were observed in basic fuchsin (46 U/mL) and methyl green (44 U/mL) respectively after 21 days of incubation, which were poor dye degraders. The triphenylmethane reductase enzyme was the responsible enzyme for the decolorization of these triphenyl methane dyes. The treatment by using fungal organisms was considered to be the cost-effective and ecofriendly method of decolourization of effluents discharged from the dye industries.展开更多
A series of new complex salts of the type [R]2[MC14] where R =[Ph-C=n-N-Ph N=N-Ph],M = Mn2＋, Co2＋, Ni2＋, Cu2＋ and Zn2＋ wereprepared and characterized by elemental analysis, molar conductance, IR and UVNis is spec...A series of new complex salts of the type [R]2[MC14] where R =[Ph-C=n-N-Ph N=N-Ph],M = Mn2＋, Co2＋, Ni2＋, Cu2＋ and Zn2＋ wereprepared and characterized by elemental analysis, molar conductance, IR and UVNis is spectral studies and magnetic measurements.The crystal structure of[Ph-C=n-N-Ph N=N-Ph]2[CuCl4] was determined by single crystal X-ray crystallography. The structure consisted of anion part and a 2,3,5-（triphenyl） tetrazolium cation as counter ions. The copper complex has a distorted tetrahedral geometry, the CI（1）-Cu-CI（2） [124.33 （2°）] and Cl（3）-Cu-Cl（4） [131.03 （2°）] angles are significantly larger than the ideal tetrahedral. The [CuCI4] anion and its counter ions are connected through a hydrogen bonds between C1 of the dianion and hetero aromatic rings by Cl-π, π-π and C-H … π, interactions.展开更多
In order to discover the novel antitumor agents,a series of N,N,1-triphenyl-1Hbenzo[d]imidazol-5-amine derivatives were designed and synthesized,and the structures were characterized by IR,H-RMS,1H and 13C NMR.X-ray c...In order to discover the novel antitumor agents,a series of N,N,1-triphenyl-1Hbenzo[d]imidazol-5-amine derivatives were designed and synthesized,and the structures were characterized by IR,H-RMS,1H and 13C NMR.X-ray crystallography showed that 4c is in monoclinic system,space group P1 with a=9.209(2),b=9.533(3),c=14.097(3)?,β=102.069(3)°,V=1202.2(5)?3,Z=2,F(000)=528,μ=1.74 mm–1,S=1.024,the final R=0.0448 and wR=0.1109.The in vitro antitumor activities of target compounds were evaluated by MTT assay against human cancer cell lines K562,HL-60,HeLa and BGC-823.The target compounds demonstrated weak or moderate antitumor activities against these cell lines.展开更多
Polystyrene （PS）/triphenyl phosphate （TPP） composites were prepared by both suspension polymerization and melt extrusion, and a comparative study of the flame retardance and mechanical properties was carried out. ...Polystyrene （PS）/triphenyl phosphate （TPP） composites were prepared by both suspension polymerization and melt extrusion, and a comparative study of the flame retardance and mechanical properties was carried out. The results showed that suspension polymerization was a better technique than melt extrusion for obtaining good dispersity of the PS/TPP composite. The TPP nanoparticles, which were approximately 50 nm in size, were homogenously and uniformly dispersed in the PS matrix by suspension polymerization in one-step. However, the PS/TPP composite was partially agglomerated, exhibiting irregularly shaped micron-scale particles as a result of melt extrusion. In contrast to the melt extrusion, the limited oxygen index （LOI） of the PS/TPP nanocomposite by suspension polymerization increased to 22.6% from 21.8%, and time to ignition （TTI） increased by 12.3%, the peak heat release rate （PHRR） decreased by 8.5%, and the total heat release （THR） decreased by 11.0%. The mechanical properties of the PS/TPP nanocomposite by suspension polymerization also increased. The tensile strength, elongation at break, and flexural strength increased by 36.4%, 8.5%, and 108%, respectively.展开更多
Four novel polymers, poly（3,6-9-decyl-carbazole-alt-1,3-benzene） （PB13CZ）, poly（3,6-9-decyl-carbazole-alt- bis（4-phenyl） （phenyl） phosphine oxide） （PTPPO38CZ）, poly（3,6-9-decyl-carbazole-alt-2,4-phenyl（d...Four novel polymers, poly（3,6-9-decyl-carbazole-alt-1,3-benzene） （PB13CZ）, poly（3,6-9-decyl-carbazole-alt- bis（4-phenyl） （phenyl） phosphine oxide） （PTPPO38CZ）, poly（3,6-9-decyl-carbazole-alt-2,4-phenyl（diphenyl） phosphine oxide） （PTPPO13CZ） and poly（3,6-9-decyl-carbazole-alt-bis（3-phenyl） （phenyl） phosphine oxide） （PTTPO27CZ） were synthesized, and their thermal, photophysical properties and device applications were further investigated to correlate the chemical structures with the photoelectric performance of bipolar host materials for phosphorescent organic light emitting diodes. All of them show high thermal stability as revealed by their high glass transition temperatures and thermal decomposition temperatures at 5% weight loss. These polymers have wide band gaps and relatively high triplet energy levels. As a result, the spin coating method was used to prepare the green phosphorescent organic light emitting diodes with polymers PTPPO38CZ, PTPPO13CZ and PTTPO27CZ as the typical host materials. The green device of polymer PTPPO38CZ as host material shows electroluminescent performance with maximum current efficiency of 2.16 cd.A-1, maximum external quantum efficiency of 0.7%, maximum brightness of 1475 cd.m-2 and reduced efficiency roll-off of 7.14% at 600 cd.m-2, which are much better than those of the same devices hosted by polymers PTTPO27CZ and PTPPO13CZ.展开更多
Quantitative reaction between copper（I） cyanide and triphenyl phosphite forms copper（I） complex [（P（OPh）3）gCug（CN）4] （1）. X-Ray crystal structure shows a catenarian polymer of tandem interconnected copper ...Quantitative reaction between copper（I） cyanide and triphenyl phosphite forms copper（I） complex [（P（OPh）3）gCug（CN）4] （1）. X-Ray crystal structure shows a catenarian polymer of tandem interconnected copper cyanide, with C and N connecting to proximal Cu atoms. The Cu atoms adopt two different conformations： one exhibits linear construction, while the other exhibits distorted tetrahedral geometry through coordinating to two cyano groups and the P donors of triphenyl phosphite molecules. The feature of 1 is the propagation pattern of two- and four-coordination along with the chain. IR and electronic absorption spectra also confirm the established single crystal structure. Thermal analysis indicates that 1 has a high thermal stability. 3-D fluorescence result shows the middle absorption peaks with the maximum excitement and emission wavelength 342 and 350 nm, respectively. Cyclic voltammogram in DMSO, DMF and MeCN gives a midpoint voltage of --0.003, 0.061 and 0.137 V versus SCE, respectively, showing the different solvent virtue on reduction potential.展开更多
文摘Jadomycin is an antibiotic that has shown activities against bacteria, yeasts and fungi as well as cytotoxic properties to cancer cells. Because of the wide range of its inhibitory actions, jadomycin shows promise as a novel antibiotic and cancer treatment drug. Streptomyces venezuelae are aerobic bacteria that produce jadomycin and the size of bacterial population can significantly affect the yield of jadomycin. Therefore, the bacterial population must be accurately measured in order to standardize the reproducibility of jadomycin production process. In this study, a dehydrogenase activity measurement test, using triphenyl tetrazolium chloride (TTC), was used to measure the dehydrogenase activity of Streptomyces venezuelae during growth in maltose-yeast extract-malt extract (MYM) broth. The aims were to evaluate the effectiveness of the test for measuring microbial growth and to study the effects of the test conditions (incubation time, incubation temperature and medium pH) on triphenyl formazan (TF) yield. The results showed that the TF yield was highly correlated to the optical density. The highest TF yield was observed at a pH of 6 at all incubation times and temperature. Lower TF yields were obtained at higher temperature (40 and 50oC) compared to those obtained at lower temperatures (22 and 30oC). The difference between the yields obtained at 22oC and 30oC were not significant. The differences between incubation time were also not significant. The recommended test conditions are an incubation time of 1 hour at a temperature of 30oC and a pH of 6 followed by three extractions using methanol.
文摘The structures and electronic spectra of the derivatives of C60-P-2,4,6-triphenyl borazinc have been studied by using AM 1 method. The calculated results indicate that this kind of compounds has a lower energy difference between HOMO and LUMO. It is found that the electron cloud on unoccupied frontier orbital mainly comes from the contribution of C60, while that on occupied frontier orbital mainly concentrates on the side chain. A long-lived charge-separated state may occur in the objective compounds.
文摘ByBimolecular Nucleophilic Substitution, four new types of alkylene triphenyl double quaternary phosphonium salt were synthesized respectively by using triphenylphosphine, 1,3-dibromopropane, 1,6-dibromohexane,1,10-dibromo- decane, 1,12-dibromododecane as raw materials and using DMAC as the solvent, under a certain temperature and reac- tion time. The productivity is 58% - 83%. The molecular structures of the products were characterized by IR, NMR and elemental analysis. The sterilizing effect of 1,6-hexylidene triphenyl double phosphonium bromide(HTDPB) and 1,12- dodecylidene triphenyl double phosphonium bromide(DoTDPB) was evaluated by using extinct dilution method.The experimental result shows that the sterilizing effect of DoTDPB is better than the effect of HTDPB under the same drug concentration and contact time. When the concentration of DoTDPB was 20 mg/L and the contact time was 0.5 h, the sterilizing rate of DoTDPB used to kill saprophytic bacteria (TGB), sulfate-reducing bacteria (SRB) and iron bacteria (IB) was 95.56%, 84% and 99.58% respectively.
文摘The new tetracarbonyl - chromium-triphenyl phosphine complex was synthesized and characterized using ultraviolet（UV）-visible,Fourier transform infrared（FTIR）,and nuclear magnetic resonance（NMR） techniques.The characterization results confirm the molecular structure of the new complex.The z-scan measurements were done by diode laser[continuous wave（CW）]to estimate the nonlinear optical parameter（X^3）.The results led to calculate three parameters：the groundstate cross sections（σ_g）,the excited-state cross sections（σ_（ex））,and thermo-optic coefficient of the new complex.This study indicated that our complex is a suitable for photonic applications.
文摘Six triphenylmethane dyes viz., bromophenol blue, basic fuchsin, methyl violet, methyl green, ethyl violet and malachite green were studied for their decolorization by Fomitopsis feei. Among, basic fuchsin (98%) was maximum decolorized followed by bromophenol blue (96.8%). However, the rate of bromophenol blue decolorization was very fast. There was no correlation between the lignolytic activity and dye decolurization of the dyes. The highest laccase and lignin peroxidase activities were observed in basic fuchsin (46 U/mL) and methyl green (44 U/mL) respectively after 21 days of incubation, which were poor dye degraders. The triphenylmethane reductase enzyme was the responsible enzyme for the decolorization of these triphenyl methane dyes. The treatment by using fungal organisms was considered to be the cost-effective and ecofriendly method of decolourization of effluents discharged from the dye industries.
文摘A series of new complex salts of the type [R]2[MC14] where R =[Ph-C=n-N-Ph N=N-Ph],M = Mn2＋, Co2＋, Ni2＋, Cu2＋ and Zn2＋ wereprepared and characterized by elemental analysis, molar conductance, IR and UVNis is spectral studies and magnetic measurements.The crystal structure of[Ph-C=n-N-Ph N=N-Ph]2[CuCl4] was determined by single crystal X-ray crystallography. The structure consisted of anion part and a 2,3,5-（triphenyl） tetrazolium cation as counter ions. The copper complex has a distorted tetrahedral geometry, the CI（1）-Cu-CI（2） [124.33 （2°）] and Cl（3）-Cu-Cl（4） [131.03 （2°）] angles are significantly larger than the ideal tetrahedral. The [CuCI4] anion and its counter ions are connected through a hydrogen bonds between C1 of the dianion and hetero aromatic rings by Cl-π, π-π and C-H … π, interactions.
基金Supported by the “Climbing Program”(pdjh2019b0497)Special Funds,the Foundation of the Department of Education of Guangdong Province(2018KZDXM070,2017KZDXM085,2017KQNCX204)College Students Innovation and Entrepreneurship Training Program of Wuyi University and Foundation for Young Talents(2018KQNCX272,2018KQNCX273)
文摘In order to discover the novel antitumor agents,a series of N,N,1-triphenyl-1Hbenzo[d]imidazol-5-amine derivatives were designed and synthesized,and the structures were characterized by IR,H-RMS,1H and 13C NMR.X-ray crystallography showed that 4c is in monoclinic system,space group P1 with a=9.209(2),b=9.533(3),c=14.097(3)?,β=102.069(3)°,V=1202.2(5)?3,Z=2,F(000)=528,μ=1.74 mm–1,S=1.024,the final R=0.0448 and wR=0.1109.The in vitro antitumor activities of target compounds were evaluated by MTT assay against human cancer cell lines K562,HL-60,HeLa and BGC-823.The target compounds demonstrated weak or moderate antitumor activities against these cell lines.
文摘Polystyrene （PS）/triphenyl phosphate （TPP） composites were prepared by both suspension polymerization and melt extrusion, and a comparative study of the flame retardance and mechanical properties was carried out. The results showed that suspension polymerization was a better technique than melt extrusion for obtaining good dispersity of the PS/TPP composite. The TPP nanoparticles, which were approximately 50 nm in size, were homogenously and uniformly dispersed in the PS matrix by suspension polymerization in one-step. However, the PS/TPP composite was partially agglomerated, exhibiting irregularly shaped micron-scale particles as a result of melt extrusion. In contrast to the melt extrusion, the limited oxygen index （LOI） of the PS/TPP nanocomposite by suspension polymerization increased to 22.6% from 21.8%, and time to ignition （TTI） increased by 12.3%, the peak heat release rate （PHRR） decreased by 8.5%, and the total heat release （THR） decreased by 11.0%. The mechanical properties of the PS/TPP nanocomposite by suspension polymerization also increased. The tensile strength, elongation at break, and flexural strength increased by 36.4%, 8.5%, and 108%, respectively.
基金financially supported by the Major Research Program from the State Ministry of Science and Technology(No.2012CB933301)the National Natural Science Foundation of China(No.21574068)+3 种基金the Priority Academic Program Development of Jiangsu Higher Education Institutions(No.YX03001)Natural Science Foundation of Jiangsu Province(No.BM2012010)Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.15KJB150022)Jiangsu Government Scholarship for Overseas Studies
文摘Four novel polymers, poly（3,6-9-decyl-carbazole-alt-1,3-benzene） （PB13CZ）, poly（3,6-9-decyl-carbazole-alt- bis（4-phenyl） （phenyl） phosphine oxide） （PTPPO38CZ）, poly（3,6-9-decyl-carbazole-alt-2,4-phenyl（diphenyl） phosphine oxide） （PTPPO13CZ） and poly（3,6-9-decyl-carbazole-alt-bis（3-phenyl） （phenyl） phosphine oxide） （PTTPO27CZ） were synthesized, and their thermal, photophysical properties and device applications were further investigated to correlate the chemical structures with the photoelectric performance of bipolar host materials for phosphorescent organic light emitting diodes. All of them show high thermal stability as revealed by their high glass transition temperatures and thermal decomposition temperatures at 5% weight loss. These polymers have wide band gaps and relatively high triplet energy levels. As a result, the spin coating method was used to prepare the green phosphorescent organic light emitting diodes with polymers PTPPO38CZ, PTPPO13CZ and PTTPO27CZ as the typical host materials. The green device of polymer PTPPO38CZ as host material shows electroluminescent performance with maximum current efficiency of 2.16 cd.A-1, maximum external quantum efficiency of 0.7%, maximum brightness of 1475 cd.m-2 and reduced efficiency roll-off of 7.14% at 600 cd.m-2, which are much better than those of the same devices hosted by polymers PTTPO27CZ and PTPPO13CZ.
文摘Quantitative reaction between copper（I） cyanide and triphenyl phosphite forms copper（I） complex [（P（OPh）3）gCug（CN）4] （1）. X-Ray crystal structure shows a catenarian polymer of tandem interconnected copper cyanide, with C and N connecting to proximal Cu atoms. The Cu atoms adopt two different conformations： one exhibits linear construction, while the other exhibits distorted tetrahedral geometry through coordinating to two cyano groups and the P donors of triphenyl phosphite molecules. The feature of 1 is the propagation pattern of two- and four-coordination along with the chain. IR and electronic absorption spectra also confirm the established single crystal structure. Thermal analysis indicates that 1 has a high thermal stability. 3-D fluorescence result shows the middle absorption peaks with the maximum excitement and emission wavelength 342 and 350 nm, respectively. Cyclic voltammogram in DMSO, DMF and MeCN gives a midpoint voltage of --0.003, 0.061 and 0.137 V versus SCE, respectively, showing the different solvent virtue on reduction potential.
