The triphosphates and homodinucleotides of AZT and d4T have been efficiently synthesized from the corresponding nucleoside 5-H-phosphonate monoesters via the reactive pyridinium phosphoramidate intermediates.
基金National Natural Science Foundation of China (Nos. 21002041 and 21262014)Natural Science Foundation of Jiangxi Province (No. 20114BAB203008)+2 种基金Project of the Science Funds of Jiangxi Education Office (No. GJJ12589)Key Project of Chinese Ministry of Education (No. 212092)Scientific Research Foundation of Chinese Ministry of Human Resources and Social Security for Returned Chinese Scholars for financial support
文摘The triphosphates and homodinucleotides of AZT and d4T have been efficiently synthesized from the corresponding nucleoside 5-H-phosphonate monoesters via the reactive pyridinium phosphoramidate intermediates.
