Four new isoflavanones with isoprenoid units,named triquetrumones E-H(1-4),were isolated from the whole plants of Tadehagi triquetrum.The structures were elucidated on the basis of spectroscopic analyses,including app...Four new isoflavanones with isoprenoid units,named triquetrumones E-H(1-4),were isolated from the whole plants of Tadehagi triquetrum.The structures were elucidated on the basis of spectroscopic analyses,including application of MS,UV,IR,1D and 2D NMR spectroscopic techniques.展开更多
The knowledge of the nutritional requirements and their relation to the physiology of marine algae growth is key to incorporate new species into aquaculture, whose dynamics tend to be largely unknown. The use of <i...The knowledge of the nutritional requirements and their relation to the physiology of marine algae growth is key to incorporate new species into aquaculture, whose dynamics tend to be largely unknown. The use of <i><span style="font-family:Verdana;">Alsidium triquetrum</span></i><span style="font-family:Verdana;"> in the pharmacological industry depends on its availability in the </span><span style="font-family:Verdana;">natural environment, occasionally scarce. As macroalgae cultivation gains</span><span style="font-family:Verdana;"> momentum worldwide, it is important to know how the effects of nutrients are modulated in the thallus during cultivation. The linking of the relative growth rates (RGR) of </span><i><span style="font-family:Verdana;">A. triquetrum</span></i><span style="font-family:Verdana;"> and their relation with the macronutrients N (nitrogen), P (phosphorus) and K (potassium) at the tissue level under culture conditions constitutes the main contribution of this article. P levels tend to decrease as the plant completes its development. Both the concentration of N and P are higher in the stipe for the month of July, N (25.31 ± 0.26) vs P (0.846 ± 0.02) period when the highest vegetative development is reached. The N and P modulate the patterns of the species’ development over the an</span><span style="font-family:Verdana;">nual cycle, unlike K, which is not considered a limiting factor. When the</span><span style="font-family:Verdana;"> tem</span><span style="font-family:Verdana;">perature and lighting are not favorable for growth, the plant simply accu</span><span style="font-family:Verdana;">mulates these compounds. As environmental conditions change, these </span><span style="font-family:Verdana;">stored</span><span style="font-family:Verdana;"> compounds are actively used in their growth. The specimens with an initial weight of 50 g present the best accumulated biomass (RGR) throughout the annual cycle.</span>展开更多
Triquetrum fractures are the second most common carpal fractures after scaphoid. However they are seldom encountered due to their clinical symptoms and since they cause less functional disability. They can be misdiagn...Triquetrum fractures are the second most common carpal fractures after scaphoid. However they are seldom encountered due to their clinical symptoms and since they cause less functional disability. They can be misdiagnosed as soft-tissue injuries by considering the similar localization of pain and prolonged symptoms. The majority of triquetrum fractures can be diagnosed with direct X-ray. Obtaining three plane (anterior-posterior, lateral and oblique) X-rays is especially important in diagnosing dorsal chip fractures. Accurate diagnosis provides both controlling the symptoms with adequate immobilization, sufficient information of the patient in the acute period and preventing unnecessary diagnostic work up in the subacute period because of prolonged discomfort. In our study, fifteen patients with isolated triquetrum fractures admitted within six year period were presented with their clinical, radiological features and treatment outcomes.展开更多
Trapezoid bone fracture is the least common fracture owing to the fact that it is strictly bounded to scaphoid, capitate and the base of the second metacarpal. Isolated fractures are rarely seen and usually related to...Trapezoid bone fracture is the least common fracture owing to the fact that it is strictly bounded to scaphoid, capitate and the base of the second metacarpal. Isolated fractures are rarely seen and usually related to the high energy trauma. It is conservatively treated without dislocation. Triquetrum fractures are the second least common fractures among carpal bones. The body fractures are usually caused by a fall onto an open flexed hand. Non-displaced fractures can be treated conservatively. Our aim is to remind those rare fractures of the carpal bones that accompany the wrist trauma, which can require additional radiological studies.展开更多
Objective To study the chemical constituents from Desmodium triquetrum and their antihyperlipidemic activities. Methods The constituents of D. triquetrumwere isolated and purified using various column chromatographies...Objective To study the chemical constituents from Desmodium triquetrum and their antihyperlipidemic activities. Methods The constituents of D. triquetrumwere isolated and purified using various column chromatographies. Their chemical structures were elucidated using extensive spectroscopic methods. The lipid-lowering effects of the isolates were evaluated in HepG2 cells. Results Nine compounds were obtained from the ethanol extract of D. triquetrum and determined to be 6＇-O-cis-p-coumaroyl- 3,5-dihydroxyphenyl-β-D-glucopyranoside （1）, tadehaginoside （2）, rutin （3）, quercetin-3-O-β-D-glucopyranoside （4）, quercetin-3-O-β-D-galactopyranoside （5）, 6-O-（E）-p-hydroxy-cinnamoyl-β-glucose （6）, 6-O-（E）-p-hydroxy-cinnamoyl-α-glucose （7）, kaempferol-3-O-β-D-rutinoside （8）, and 3-O-β-D-galacopyranosyl （6-1）-α-L- rhamnosyl quercetin （9）. Compounds 1 and 2 significantly reduced the intracellular content of total cholesterols and triglycerides. Conclusion Compound 1 is a new phenolic compound and exhibits potent anti-hyperlipidemic activity. Additionally, compounds 6 and 7 are isolated from D. triquetrum for the first time.展开更多
基金The authors are grateful to National Basic Research Program of China(973 Program 2009CB522300)the Chinese Academy of Science(KSCX2-EW-R-15)for financial support and to the members of the analytical group in the State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,for the spectral measurements.
文摘Four new isoflavanones with isoprenoid units,named triquetrumones E-H(1-4),were isolated from the whole plants of Tadehagi triquetrum.The structures were elucidated on the basis of spectroscopic analyses,including application of MS,UV,IR,1D and 2D NMR spectroscopic techniques.
文摘The knowledge of the nutritional requirements and their relation to the physiology of marine algae growth is key to incorporate new species into aquaculture, whose dynamics tend to be largely unknown. The use of <i><span style="font-family:Verdana;">Alsidium triquetrum</span></i><span style="font-family:Verdana;"> in the pharmacological industry depends on its availability in the </span><span style="font-family:Verdana;">natural environment, occasionally scarce. As macroalgae cultivation gains</span><span style="font-family:Verdana;"> momentum worldwide, it is important to know how the effects of nutrients are modulated in the thallus during cultivation. The linking of the relative growth rates (RGR) of </span><i><span style="font-family:Verdana;">A. triquetrum</span></i><span style="font-family:Verdana;"> and their relation with the macronutrients N (nitrogen), P (phosphorus) and K (potassium) at the tissue level under culture conditions constitutes the main contribution of this article. P levels tend to decrease as the plant completes its development. Both the concentration of N and P are higher in the stipe for the month of July, N (25.31 ± 0.26) vs P (0.846 ± 0.02) period when the highest vegetative development is reached. The N and P modulate the patterns of the species’ development over the an</span><span style="font-family:Verdana;">nual cycle, unlike K, which is not considered a limiting factor. When the</span><span style="font-family:Verdana;"> tem</span><span style="font-family:Verdana;">perature and lighting are not favorable for growth, the plant simply accu</span><span style="font-family:Verdana;">mulates these compounds. As environmental conditions change, these </span><span style="font-family:Verdana;">stored</span><span style="font-family:Verdana;"> compounds are actively used in their growth. The specimens with an initial weight of 50 g present the best accumulated biomass (RGR) throughout the annual cycle.</span>
文摘Triquetrum fractures are the second most common carpal fractures after scaphoid. However they are seldom encountered due to their clinical symptoms and since they cause less functional disability. They can be misdiagnosed as soft-tissue injuries by considering the similar localization of pain and prolonged symptoms. The majority of triquetrum fractures can be diagnosed with direct X-ray. Obtaining three plane (anterior-posterior, lateral and oblique) X-rays is especially important in diagnosing dorsal chip fractures. Accurate diagnosis provides both controlling the symptoms with adequate immobilization, sufficient information of the patient in the acute period and preventing unnecessary diagnostic work up in the subacute period because of prolonged discomfort. In our study, fifteen patients with isolated triquetrum fractures admitted within six year period were presented with their clinical, radiological features and treatment outcomes.
文摘Trapezoid bone fracture is the least common fracture owing to the fact that it is strictly bounded to scaphoid, capitate and the base of the second metacarpal. Isolated fractures are rarely seen and usually related to the high energy trauma. It is conservatively treated without dislocation. Triquetrum fractures are the second least common fractures among carpal bones. The body fractures are usually caused by a fall onto an open flexed hand. Non-displaced fractures can be treated conservatively. Our aim is to remind those rare fractures of the carpal bones that accompany the wrist trauma, which can require additional radiological studies.
基金National Natural Science Foundation of China (81202994,81001437)China Postdoctoral Science Foundation (2012M510361)Technological Large Platform for Comprehensive Research and Development of New Drugs in the Twelfth Five-Year Significant New Drugs Created Science and Technology Major Projects (2012ZX09301-002-001-026)
文摘Objective To study the chemical constituents from Desmodium triquetrum and their antihyperlipidemic activities. Methods The constituents of D. triquetrumwere isolated and purified using various column chromatographies. Their chemical structures were elucidated using extensive spectroscopic methods. The lipid-lowering effects of the isolates were evaluated in HepG2 cells. Results Nine compounds were obtained from the ethanol extract of D. triquetrum and determined to be 6＇-O-cis-p-coumaroyl- 3,5-dihydroxyphenyl-β-D-glucopyranoside （1）, tadehaginoside （2）, rutin （3）, quercetin-3-O-β-D-glucopyranoside （4）, quercetin-3-O-β-D-galactopyranoside （5）, 6-O-（E）-p-hydroxy-cinnamoyl-β-glucose （6）, 6-O-（E）-p-hydroxy-cinnamoyl-α-glucose （7）, kaempferol-3-O-β-D-rutinoside （8）, and 3-O-β-D-galacopyranosyl （6-1）-α-L- rhamnosyl quercetin （9）. Compounds 1 and 2 significantly reduced the intracellular content of total cholesterols and triglycerides. Conclusion Compound 1 is a new phenolic compound and exhibits potent anti-hyperlipidemic activity. Additionally, compounds 6 and 7 are isolated from D. triquetrum for the first time.
