Lone Star基金将收购巴斯夫化学建材事业部

2019年12月21日,巴斯夫与全球私募股权公司LoneStar的关联公司签署巴斯夫化学建材事业部的收购协议。现金和无债务的购买价格为31.7亿欧元。这项交易预计将在2020年第3季度完成,交易还须获得相关竞争主管部门的批准。

Lone Star向Astro所有房地产资产发起全现金收购

2017年3月6日，全球性私募股权公司Lone Star Funds发表声明：“Lone Star Real Estate Fund V附属机构宣布已向A Stro JaPan Property Group董事会提出全现金收购要约，欲按照Astro在2016年12月31目的账面价值83，667，274，000日元，

Lone Star基金将收购巴斯夫化学建材事业部

12月21日,巴斯夫与全球私募股权公司Lone Star的关联公司签署巴斯夫化学建材事业部的收购协议。现金和无债务的购买价格为31.7亿欧元。这项交易预计将在2020年第三季度完成,交易还须获得相关竞争主管部门的批准。巴斯夫欧洲公司执行董事会成员、负责化学建材业务部的董善励(Saori Dubourg)表示:"我们的目标是为化学建材业务部找到一个可以充分发挥其潜力的新家,在Lone Star的管理之下,化学建材业务团队能够以建筑行业特有的模式专注于业务增长。"

骨科机器人联合Starr骨盆复位架治疗Tile C型骨盆环骨折

目的:探讨骨科机器人联合Starr骨盆复位架治疗Tile C型骨盆环骨折的临床疗效。方法:2019年10月至2021年5月采用机器人联合Starr骨盆复位架治疗14例Tile C型骨盆环骨折患者,男9例,女5例;年龄33~69岁。14例患者均为新鲜闭合骨折且不合并股骨、胫腓骨骨折等损伤。入院后4~7 d完成手术,术中在可透视碳素床,通过Starr骨盆复位架牵引复位骨盆环,联合骨科机器人治疗C型骨盆环骨折。观察手术时间、出血量、单枚螺钉置入透视次数、骨折复位质量、患肢功能及并发症等。采用Matta评分标准进行放射学复位评价,末次随访采用Majeed骨盆功能评分系统进行临床疗效评价。结果:14例患者均顺利完成手术,手术时间84~141 min,手术出血量20~50 ml,单枚螺钉置入透视次数4~9次。14例患者均获得随访,随访时间12~24个月。术后所有骨折获得骨性愈合,愈合时间3~7个月,未发现内固定断裂、螺钉松动、感染、神经损伤等并发症。依据Matta影像学复位评估标准:优9例,良4例,可1例。末次随访采用Majeed骨盆功能评分系统:优10例,良4例。结论:机器人联合Starr骨盆复位架治疗C型骨盆环新鲜骨折操作简单、缩短了手术和麻醉时间、并发症少,降低了手术风险,实现了骨盆骨折的微创治疗。但对于陈旧性骨折,因骨折复位困难,该技术并不适用。对于螺钉进钉点区域粉碎的骨折,通道螺钉置入困难,建议采用其他方式固定。对于伴有骨盆外伤史或骨盆发育异常者,术前需仔细评估有无经皮螺钉通道,避免损伤神经、血管。

日本沼虾StAR基因克隆及其低氧胁迫下表达分析

为了研究类固醇激素合成急性调节蛋白(steroidogenic acute regulatory protein, StAR)在日本沼虾应答低氧胁迫过程中所发挥的作用,实验应用c DNA末端快速扩增(RACE)PCR技术克隆了日本沼虾StAR全长cDNA序列,并利用在线软件对其序列特征进行生物信息学分析,采用半定量RT-PCR方法分析StAR在日本沼虾不同组织的分布情况,采用实时荧光定量PCR(qRT-PCR)与免疫印迹(Western blot)技术对其在不同低氧胁迫阶段中的表达规律进行检测,观察低氧胁迫下精巢组织中StAR蛋白免疫组化定位。结果显示,日本沼虾StAR其cDNA全长3 361 bp (NCBI登录号:MW263908),包括5′-UTR 323 bp,3′-UTR 2 129 bp,开放阅读框909 bp,编码302个氨基酸。氨基酸序列比对及系统进化分析结果显示,日本沼虾StAR基因与三疣梭子蟹等甲壳动物StAR聚类一支,具有最近的亲缘关系。半定量RT-PCR检测结果显示,StAR在日本沼虾不同组织中均有表达,其表达量在肝胰腺和心脏组织中最低,在精巢组织中表达处于较高水平。使用qRT-PCR技术检测日本沼虾精巢中StAR在低氧胁迫下时空表达情况,结果表明,与对照组相比,低氧处理组精巢中StAR基因表达量在1~48 h均显著上调,而在低氧处理组96 h显著降低。此外,本实验对StAR进行了原核表达及抗血清制备,采用Western blot检测StAR蛋白表达丰度基本与基因表达模式相似,免疫组化结果显示,StAR蛋白在精细胞与间质细胞中均有表达。综上所述,长期低氧胁迫显著降低了StAR基因的转录表达水平,并且该基因可能在类固醇合成路径及精子发生过程中均发挥重要作用。本研究结果为进一步解析日本沼虾类固醇激素合成分子机制奠定基础。

STAR基因与东湖杂交奶绵羊繁殖性状的关联分析

本实验旨在探究类固醇激素合成急性调节蛋白(Steroidogenic Acute Regulatory Protein,STAR)基因多态性与东湖杂一代奶绵羊发情鉴定评分、产羔数的相关性,鉴定出影响绵羊繁殖性能的关键性位点。本研究以339只东湖杂一代奶绵羊为研究对象,采用竞争性等位基因特异性PCR(KASP)技术对STAR基因的g.31959747T>C、g.31959875A>C2个位点进行基因分型,并利用GLM模型对SNP位点与发情鉴定评分和产羔数进行关联分析。结果表明,g.31959747T>C与奶绵羊发情鉴定评分呈极显著相关,TT型的发情表现更优,但与产羔数差异不显著;g.31959875A>C与发情评分和产羔数均无显著关系;聚合基因型与繁殖性状的关联分析结果表明,TCAC型个体在发情评分、平均产羔数方面均较低。综上,STAR基因g.31959747T>C位点是影响奶绵羊发情评分的关键性位点,可根据育种目标将g.31959747T>C位点作为提高奶绵羊同期发情效果的分子标记,同时将TCAC聚合基因型及时淘汰。本研究结果可为奶绵羊繁殖性状的选育提供参考。

STAR基因在不同发育期绵羊睾丸和附睾中的表达与组织分布

为探讨STAR基因在发育的绵羊睾丸和附睾中的表达模式及潜在功能,该研究采集3月龄、 1周岁和3周岁藏绵羊睾丸和附睾(头、体和尾)组织样本,利用实时荧光定量PCR、蛋白免疫印迹和免疫组织荧光染色法检测STAR基因的表达及其编码蛋白的细胞定位。结果发现,随着年龄的增加,在藏绵羊睾丸和附睾(附睾头除外)中STAR基因在转录水平的表达总体呈下降趋势,而在蛋白质水平的表达呈上调趋势。STAR蛋白主要存在于藏绵羊睾丸间质细胞和附睾假复层纤毛上皮主细胞。鉴于间质细胞和主细胞的主要生物学功能是分泌睾酮和分泌促进精子成熟所需的蛋白质,由此推测,STAR基因可能主要在睾丸间质细胞和附睾主细胞的发育和功能维持中发挥作用,进而促进雄激素的合成和精子的成熟。

Two-dimensional Parameter Relationships for W UMa-type Systems Revisited

Reviewing the empirical and theoretical parameter relationships between various parameters is a good way to understand more about contact binary systems.In this investigation,two-dimensional(2D)relationships for P–MV(system),P–L1,2,M1,2–L1,2,and q–Lratiowere revisited.The sample used is related to 118 contact binary systems with an orbital period shorter than 0.6 days whose absolute parameters were estimated based on the Gaia Data Release 3 parallax.We reviewed previous studies on 2D relationships and updated six parameter relationships.Therefore,Markov chain Monte Carlo and Machine Learning methods were used,and the outcomes were compared.We selected 22 contact binary systems from eight previous studies for comparison,which had light curve solutions using spectroscopic data.The results show that the systems are in good agreement with the results of this study.

Free Energy of Anisotropic Strangeon Stars

Can pulsar-like compact objects release further huge free energy besides the kinematic energy of rotation?This is actually relevant to the equation of state of cold supra-nuclear matter,which is still under hot debate.Enormous energy is surely needed to understand various observations,such asγ-ray bursts,fast radio bursts and softγ-ray repeaters.In this paper,the elastic/gravitational free energy of solid strangeon stars is revisited for strangeon stars,with two anisotropic models to calculate in general relativity.It is found that huge free energy(>10^(46)erg)could be released via starquakes,given an extremely small anisotropy((p_(t)-p_(r))/p_(r)~10^(-4),with pt/pr the tangential/radial pressure),implying that pulsar-like stars could have great potential of free energy release without extremely strong magnetic fields in the solid strangeon star model.

Searching For Wide Binary Stars with Non-coeval Components in the Southern Sky

We have completed our observational program to search for wide binary systems with non-coeval components in the southern sky and report our results here.The final set of four systems was spectroscopically investigated in this paper.No binary systems with components of different ages were found among them.Taking into account our previous studies,we estimate the fraction of such binaries(i.e.,binaries formed,presumably,by capture)to be not higher than 0.06%.The study will be continued on the northern sky.

靶向小鼠Star基因的CRISPR/Cas9系统构建与打靶效力评价

目的利用CRISPR/Cas9系统对小鼠Star基因进行精确编辑,构建模拟人类STAR基因突变的细胞模型。方法选择中国先天性类脂质性肾上腺皮质增生症(CLAH)患者的热点突变区域,并设计相应的单导向RNA(sgRNA)。构建表达sgRNA的重组质粒,将其与慢病毒包装质粒共同转染至HEK-293T细胞并制备慢病毒颗粒以感染小鼠TCMK细胞。采用嘌呤霉素进行病毒感染后阳性细胞的筛选,提取阳性细胞的基因组DNA,通过聚合酶链式反应(PCR)扩增目标位点的基因组DNA片段,并利用TA克隆和Sanger测序技术,对编辑位点与效率进行统计分析。结果成功设计了有效的sgRNA序列,并利用CRISPR/Cas9系统成功构建了编辑小鼠Star基因的细胞模型。结论本研究通过精确编辑小鼠Star基因,成功构建了模拟人类STAR基因突变的CRISPR/Cas9系统,为深入研究CLAH的致病机制及探索潜在治疗方法提供有力工具,具有重要的科学意义和应用价值。

Spectroscopic Observations of Ten Galactic Wolf-Rayet Stars at Bosscha Observatory:Determination of Stellar Parameters and Mass-loss Rates

We present optical spectra of 10 Galactic Wolf-Rayet(WR)stars that consist of five WN and five WC stars.The optical observation was conducted using a low-resolution spectrograph NEO-R1000(λ/Δλ~1000)at GAO-ITB RTS(27.94 cm,F/10.0),Bosscha Observatory,Lembang.We implemented stellar atmosphere Postdam Wolf-Rayet(PoWR)grid modeling to derive stellar parameters.The normalized optical spectrum can be used to find the best model from the available PoWR grid,then we could derive stellar temperature and transformation radius.To derive luminosity,stellar radius and color excess,we conducted a Spectral Energy Distribution(SED)analysis with additional data on the near-ultraviolet spectrum from the International Ultraviolet Explorer(IUE)database,and UBV and 2MASS JHK broadband filter data.Additional analysis to derive asymptotic terminal wind velocity was conducted from the P-Cygni profile analysis of the high-resolution IUE ultraviolet spectrum.With previously derived parameters,we could determine the mass loss rate of the WR stars.Furthermore,we compared our results with previous work that used PoWR code and the differences are not more than 20%.We conclude that the PoWR spectral grid is sufficient to derive WR stellar parameters quickly and could provide more accurate initial parameter input to the PoWR program code.

Periodic Variation Studies of the Two Short Period W UMa-type Eclipsing Binaries: LX Lyn and V0853 Aur

In this paper,new light curves(LCs) of contact eclipsing binary(CEB) systems LX Lyn and V0853 Aur are presented and analyzed by using the 2015 version of the Wilson-Devinney(W-D) code.In order to explain their asymmetric LCs,cool starspots on the components were employed.It is suggested that their fill-out degrees are f=12.0%(LX Lyn) and f=26.3%(V0853 Aur).At the same time,we found that LX Lyn is a W-type eclipsing binary(EB) with an orbital inclination of i=84°.88 and a mass ratio of q=2.31.V0853 Aur is also a W-type CEB with a mass ratio of q=2.77 and an orbital inclination of i= 79°.26.Based on all available times of light minimum,their orbital period changes are studied by using the O-C method.The O-C diagram of LX Lyn reveals a cyclic oscillation with a period of about 14.84 yr and an amplitude of 0.0019 days,which can be explained by the light-travel time effect(LTTE) due to the presence of a third body with a minimum mass of0.06M_⊙.For V0853 Aur,it is discovered that the O-C diagram of the system also shows a cyclic oscillation with a period of 9.64 yr and an amplitude of 0.03365 days.The cyclic oscillation of V0853 Aur can be attributed to the LTTE by means of a third body with a mass no less than 3.77M_⊙.The third body may play an important role in the formation and evolution of these systems.

Formation of a Rapidly Rotating Classical Be-star in a Massive Close Binary System

This paper investigates the spin-up of a mass-accreting star in a close binary system passing through the first stage of mass exchange in the Hertzsprung gap. Inside an accreting star, angular momentum is carried by meridional circulation and shear turbulence. The circulation carries part of the angular momentum of the accreted layers to the accretor's surface. The greater the rate of arrival of angular momentum in the accretor is, the greater this part. It is assumed that this part of the angular momentum can be removed by the disk further from the accretor. If the angular momentum in the matter entering the accretor is more than half the Keplerian value, then the angular momentum obtained by the accretor during mass exchange stage does not depend on the rate of arrival of angular momentum. The accretor may have the characteristics of a Be-star immediately after the end of mass exchange.

Rotating Massive Strangeon Stars and X-Ray Plateau of Short GRBs

Strangeon stars,which are proposed to describe the nature of pulsar-like compact stars,have passed various observational tests.The maximum mass of a non-rotating strangeon star could be high,which implies that the remnants of binary strangeon star mergers could even be long-lived massive strangeon stars.We study rigidly rotating strangeon stars in the slowly rotating approximation,using the Lennard-Jones model for the equation of state.Rotation can significantly increase the maximum mass of strangeon stars with unchanged baryon numbers,enlarging the mass-range of long-lived strangeon stars.During spin-down after merger,the decrease of radius of the remnant will lead to the release of gravitational energy.Taking into account the efficiency of converting the gravitational energy luminosity to the observed X-ray luminosity,we find that the gravitational energy could provide an alternative energy source for the plateau emission of X-ray afterglow.The fitting results of X-ray plateau emission of some short gamma-ray bursts suggest that the magnetic dipole field strength of the remnants can be much smaller than that of expected when the plateau emission is powered only by spin-down luminosity of magnetars.

On the Energy Budget of Starquake-induced Repeating Fast Radio Bursts

With a growing sample of fast radio bursts(FRBs),we investigate the energy budget of different power sources within the framework of magnetar starquake triggering mechanism.During a starquake,the energy can be released in any form through strain,magnetic,rotational,and gravitational energies.The strain energy can be converted from three other kinds of energy during starquakes.The following findings are revealed:(1)The crust can store free magnetic energy of~10^(46)erg by existing toroidal fields,sustaining 10^(6)bursts with frequent starquakes occurring due to crustal instability.(2)The strain energy develops as a rigid object spins down,which can be released during a global starquake accompanied by a glitch.However,it takes a long time to accumulate enough strain energy via spindown.(3)The rotational energy of a magnetar with P■0.1 s can match the energy and luminosity budget of FRBs.(4)The budget of the total gravitational energy is high,but the mechanism and efficiency of converting this energy to radiation deserve further exploration.

An Asymmetric Galactic Stellar Disk Traced by OB-type Stars from LAMOST DR7

Using 9943 OB-type stars from LAMOST DR7 in the solar neighborhood,we fit the vertical stellar density profile with the model including a single exponential distribution at different positions(R,Φ).The distributions of the scale heights and scale length show that the young disk traced by the OB-type stars is not axisymmetric.The scale length decreases versus the azimuthal angleΦ,i.e.,from.■kpc withΦ=-3°to■kpc withΦ=9°.Meanwhile we find signal of non-symmetry in the distribution of the scale height of the north and south of the disk plane.The scale height in the north side shows signal of flaring of the disk,while that of the south disk stays almost constant around h_(s)=130 pc.The distribution of the displaceeent of the disk plane Z_(0)also shows variance versus the azimuthal angleΦ,which displays significant differences with the warp model constrained by the Cepheid stars.We also test different values for the position of the Sun,and the distance between the Sun and the Galactic center affects the scale heights and the displacement of the disk significantly,but that does not change our conclusion that the disk is not axisymmetric.

The Structure and the Density of a Bare Quark Star in a Cold Genesis Theory of Particles

Based on the preonic structure of quarks obtained in a Cold genesis theory of particles (CGT), it was obtained a semi-empiric relation for the current mass of quarks specific to CGT but with the constants obtained with the aid of the Gell-Mann-Oakes-Renner formula, giving values close to those obtained by the Standard Model, the current quark’s volume at ordinary nuclear temperature being obtained as sum of theoretic apparent volumes of preonic kerneloids. The maximal densities of the current quarks: strange (s), charm (c), bottom (b), and top (t) resulted in the range (0.8 - 4.2) × 1018 kg/m3, as values which could be specific to possible quark stars, in concordance with previous results. By the preonic quark model of CGT, the possible structure of a quark star resulted from the intermediary transforming: Ne(2d+u)→s−¯+λ−and the forming of composite quarks with the structure: C−(λ−-s−¯-λ−) and C+(s−¯-λ−-s−¯), and of Sq-layers: C+C−C+ and C−C+C− which can form composite quarks: Hq±=(SqS¯qSq);(S¯qSqS¯q), corresponding to a constituent mass: M(Hq) = (12,642;12,711) MeV/c2, the forming of heavier quarks inside a quark star resulting as possible in the form: Dq = n3Cq, (n ≥ 3). The Tolman-Oppenheimer limit: MT=0.7M⊙for neutron stars can also be explained by the CGT’s quark model.

Analysis of the Impact of the Blazhko Effect Both on the Van Hoof Effect and Radial Velocity Amplitude in the Star RR Lyr

The Van Hoof effect is a phase shift existing between the radial velocity curves of hydrogen and metallic lines within the atmosphere of pulsating stars.In this article,we present a study of this phenomenon through the spectra of the brightest pulsating star RR Lyr of RR Lyrae stars recorded for 22 yr.We based ourselves,on the one hand,on 1268 spectra(41 nights of observation)recorded between the years 1994 and 1997 at the Observatory of Haute Provence(OHP,France)previously observed by Chadid and Gillet,and on the other hand on 1569 spectra(46nights of observation)recorded at our Oukaimeden Observatory(Morocco)between 2015 and 2016.Through this study,we have detected information on atmospheric dynamics that had not previously been detected.Indeed,the Van Hoof effect which results in a clear correlation between the radial velocities of hydrogen and those of the metallic lines has been observed and analyzed at different Blazhko phases.A correlation between the radial velocities of different metallic lines located in the lower atmosphere has been observed as well.For the first time,we were able to show that the amplitude of the radial velocity curves deduced from the lines of hydrogen and that of FeⅡ(λ4923.921?)increases toward the minimum of the Blazhko cycle and decreases toward the maximum of the same Blazhko cycle.Furthermore,we found that the Van Hoof effect is also modulated by the Blazhko effect.Thus,toward the minimum of the Blazhko cycle the Van Hoof effect is more visible and at the maximum of the Blazhko cycle,this effect is minimal.We also observed the temporal evolution of the amplitudes of the radial velocities of the lower and upper atmosphere.When observed over a long time,we can interpret it as a function of the Blazhko phases.

Enrichment of Chemical Element ^(7)Li in the Rotating Red Clump Star

About 2 percent of red clump stars are found to be the lithium-rich and thus the surface lithium increases obviously in some red clump stars.The physical mechanism of the lithium enrichment in these stars has not yet been explained satisfactorily by the evolutionary models of single stars.The flash induced internal gravity wave mixing(i.e.,IGW)could play a primary role in explaining the red clump star with lithium enrichment and it has a very significant impact on the internal structure and surface compositions of a star.Rotation can significantly increase the mixing efficiency of the internal gravity wave because the timescale for the enrichment event has been enlarged.Thermohaline mixing can explain the observed behavior of lithium on red giant stars that are more luminosity than the RGB bump.However,it has a very small effect on the diffusion of elements because its diffusion coefficient is much smaller than the one of IGW induced mixing after the core helium flash.