This paper proposes a lattice Boltzmann scheme to simulate two-dimensionalfluid transients. A set of multi-scale equations, which characterize the relations between thelattice Boltzmann equation and its corresponding ...This paper proposes a lattice Boltzmann scheme to simulate two-dimensionalfluid transients. A set of multi-scale equations, which characterize the relations between thelattice Boltzmann equation and its corresponding macroscopic equations, were derived by using theChapman-Enskog expansion. Based on these multi-scale equations and the basic equations ofmultidimensional fluid transients, two special lattice Boltzmann models were established. Numericalsimulation of one-dimensional pressure wave transmission and reflection, two-dimensional wave cornerdiffraction and hydraulic transients in a concrete spiral case show that the Lattice BoltzmannMethod (LBM) is a feasible and promising approach to simulate multidimensional transient flows.展开更多
The chaotic transients of a curved fluid conveying tube subjected to a nonlinear foundation are investigated. The assumption of the inextensibility of the tube is applied to derive the nonlinear differential equation ...The chaotic transients of a curved fluid conveying tube subjected to a nonlinear foundation are investigated. The assumption of the inextensibility of the tube is applied to derive the nonlinear differential equation of motion via the Newtonian approach, with the differential quadrature method used to discretize the curved tube model in the spatial domain. And the nonlinear dynamic motion equation is obtained. The numerical analysis shows that, the final steady states are sensitive to the initial system conditions in a large parameter region of the fluid speed. This phenomenon of chaotic transients is infrequent for fluid conveying tubes.展开更多
A new approach of generating transient chaos from two-dimensional(2D) continuous autonomous systems within finite time is presented.Based on an absolute-value switching law,the phenomenon of transient chaos takes pl...A new approach of generating transient chaos from two-dimensional(2D) continuous autonomous systems within finite time is presented.Based on an absolute-value switching law,the phenomenon of transient chaos takes place by switching between three 2D systems.Basic dynamic behavior of the systems is investigated.Numerical examples illustrate the validity of the results.展开更多
Polymer flooding in fractured wells has been extensively applied in oilfields to enhance oil recovery.In contrast to water,polymer solution exhibits non-Newtonian and nonlinear behavior such as effects of shear thinni...Polymer flooding in fractured wells has been extensively applied in oilfields to enhance oil recovery.In contrast to water,polymer solution exhibits non-Newtonian and nonlinear behavior such as effects of shear thinning and shear thickening,polymer convection,diffusion,adsorption retention,inaccessible pore volume and reduced effective permeability.Meanwhile,the flux density and fracture conductivity along the hydraulic fracture are generally non-uniform due to the effects of pressure distribution,formation damage,and proppant breakage.In this paper,we present an oil-water two-phase flow model that captures these complex non-Newtonian and nonlinear behavior,and non-uniform fracture characteristics in fractured polymer flooding.The hydraulic fracture is firstly divided into two parts:high-conductivity fracture near the wellbore and low-conductivity fracture in the far-wellbore section.A hybrid grid system,including perpendicular bisection(PEBI)and Cartesian grid,is applied to discrete the partial differential flow equations,and the local grid refinement method is applied in the near-wellbore region to accurately calculate the pressure distribution and shear rate of polymer solution.The combination of polymer behavior characterizations and numerical flow simulations are applied,resulting in the calculation for the distribution of water saturation,polymer concentration and reservoir pressure.Compared with the polymer flooding well with uniform fracture conductivity,this non-uniform fracture conductivity model exhibits the larger pressure difference,and the shorter bilinear flow period due to the decrease of fracture flow ability in the far-wellbore section.The field case of the fall-off test demonstrates that the proposed method characterizes fracture characteristics more accurately,and yields fracture half-lengths that better match engineering reality,enabling a quantitative segmented characterization of the near-wellbore section with high fracture conductivity and the far-wellbore section with low fracture conductivity.The novelty of this paper is the analysis of pressure performances caused by the fracture dynamics and polymer rheology,as well as an analysis method that derives formation and fracture parameters based on the pressure and its derivative curves.展开更多
The algebraic solitary wave and its associated eigenvalue problem in a deep stratified fluid with a free surface and a shallow upper layer were studied. And its vertical structure was examined. An exact solution for t...The algebraic solitary wave and its associated eigenvalue problem in a deep stratified fluid with a free surface and a shallow upper layer were studied. And its vertical structure was examined. An exact solution for the derived 2D Benjamin-Ono equation was obtained, and physical explanation was given with the corresponding dispersion relation. As a special case, the vertical structure of the weakly nonlinear internal wave for the Holmboe density distribution was numerically investigated, and the propagating mechanism of the internal wave was studied by using the ray theory.展开更多
This paper presents the analytical solutions in Laplace domain for two-dimensional nonsteady flow of slightly compressible liquid in porous media with double porosity by using the methods of integral transforms and va...This paper presents the analytical solutions in Laplace domain for two-dimensional nonsteady flow of slightly compressible liquid in porous media with double porosity by using the methods of integral transforms and variables separation. The effects of the ratio of storativities to , interporosity flow parameter on the pressure behaviors for a vertically fractured well with infinite conductivity are investigated by using the method of numerical inversion. The new log-log diagnosis graph of the pressures is given and analysed.展开更多
BACKGROUND: Previous studies have confirmed the existence of specific proteins in body fluid of Parkinson's disease (PD) patients. However, the existing research has contained several interference factors with poo...BACKGROUND: Previous studies have confirmed the existence of specific proteins in body fluid of Parkinson's disease (PD) patients. However, the existing research has contained several interference factors with poor reproducibility and has not focused on patients grouped according to disease duration. OBJECTIVE: To verify differential expression of proteins in cerebrospinal fluid of PD patients grouped in order of disease severity through the use of two-dimensional electrophoresis-mass spectrometry methods. DESIGN, TIME AND SETTING: The proteomic-based, case-control study was performed between September 2008 and June 2009 at the Key Laboratory of Neurology in the First Affiliated Hospital of Chongqing Medical University. PARTICIPANTS: A total of 52 outpatients and/or inpatients, who were admitted to the Department of Neurology in the First Affiliated Hospital of Chongqing Medical University between 2008 and 2009, were randomized into the present study. Among them, 27 PD patients served as the PD group and were assigned to three subgroups according to modified Webster, Hoehn, and Yahr rating scales: 14 = mild, 8 = moderate, and 5 = severe; non-PD group of 16 patients included 5 cases of viral meningitis, 3 cases of acute myelitis, 1 case of Guillain-Barre syndrome, 2 cases of tuberculous meningitis, 2 cases of restless legs syndrome, and 3 cases of essential tremor; control group (n = 9) consisted of muscular tension headache in 6 cases, as well as syncope, trigeminal neuralgia, idiopathic orthostatic hypotension in 1 case. METHODS: Cerebrospinal fluid was collected from the involved patients using the lumbar puncture method. Proteins in the cerebrospinal fluid were separated by two-dimensional electrophoresis. MAIN OUTCOME MEASURES: Characteristics of protein electrophoresis patterns were analyzed, differentially expressed proteins were detected using matrix-assisted laser desorption ionization time of flight mass spectrometry, and protein data were analyzed in the Mascot database. RESULTS: Five protein electropherograms were analyzed by PDQuest 8.0, and (789 ± 32) protein spots were observed. There were significant differences in four protein spots in each of the PD sub-groups compared with the non-disease and control groups. Expression was down-regulated in three protein spots and up-regulated in one protein spot; 100% repetition rate was observed in four protein spots. According to the Mascot database, protein spots with down-regulated expression were as follows: DNA-guided RNA polymerase III subunit RPC5 (score: 50 points); double serine, threonine, and tyrosine protein kinase (score: 64 points, P 〈 0.05); activity-regulated cytoskeleton-associated protein (score: 58 points, P 〈 0.05). However, G2 mitotic-specific cyclin was up-regulated (score: 84 points, P 〈 0.05). CONCLUSION: Differential protein expression in the cerebrospinal fluid of PD patients was detected by two-dimensional electrophoresis-mass spectrometry, revealing changes in DNA-guided RNA polymerase III subunit RPC5, double serine, threonine, and tyrosine protein kinase, activity-regulated cytoskeleton-associated protein, and G2 mitotic cell cyclin, with good reproducibility.展开更多
A theoretical equation is developed which describes the response of the current transients to a constant potential at tubular electrodes for a reversible electrode reaction in the flowing fluid.
The transient Rayleigh wave exploration has high detection accuracy in shallow exploration. The effect of detection array is comprehensive reflection of the velocity of rock and soil mass. Therefore, the roiling multi...The transient Rayleigh wave exploration has high detection accuracy in shallow exploration. The effect of detection array is comprehensive reflection of the velocity of rock and soil mass. Therefore, the roiling multi-channel transient acquisition system has been adopted in this study, which turns one dimensional transient Rayleigh wave exploration into two dimensions, consequently, the two-dimensional velocity distribution of rock and soil mass under the survey line has been achieved. Through comparing with the shallow seismic reflected wave exploration, the result indicates that the rolling multi-channel transient acquisition system has accurate resolution. Thus, in the process of the shallow reflected wave exploration, if the surface wave has developed, the coalition between the reflected wave exploration and the two-dimensional transient Rayleigh wave exploration should actualize the accuracy of exploration.展开更多
Journal bearings are important parts to keep the high dynamic performance of rotor machinery. Some methods have already been proposed to analysis the flow field of journal bearings, and in most of these methods simpli...Journal bearings are important parts to keep the high dynamic performance of rotor machinery. Some methods have already been proposed to analysis the flow field of journal bearings, and in most of these methods simplified physical model and classic Reynolds equation are always applied. While the application of the general computational fluid dynamics (CFD)-fluid structure interaction (FSI) techniques is more beneficial for analysis of the fluid field in a journal bearing when more detailed solutions are needed. This paper deals with the quasi-coupling calculation of transient fluid dynamics of oil film in journal bearings and rotor dynamics with CFD-FSI techniques. The fluid dynamics of oil film is calculated by applying the so-called "dynamic mesh" technique. A new mesh movement approacb is presented while the dynamic mesh models provided by FLUENT are not suitable for the transient oil flow in journal bearings. The proposed mesh movement approach is based on the structured mesh. When the joumal moves, the movement distance of every grid in the flow field of bearing can be calculated, and then the update of the volume mesh can be handled automatically by user defined function (UDF). The journal displacement at each time step is obtained by solving the moving equations of the rotor-bearing system under the known oil film force condition. A case study is carried out to calculate the locus of the journal center and pressure distribution of the journal in order to prove the feasibility of this method. The calculating results indicate that the proposed method can predict the transient flow field of a journal bearing in a rotor-bearing system where more realistic models are involved. The presented calculation method provides a basis for studying the nonlinear dynamic behavior of a general rotor-bearing system.展开更多
The Songliao Basin is famous for the Daqing Oilfield, the biggest in China. However, no economic hydrocarbon reservoir has been found in the northeastern Binbei district. Its thermal history, which is of great importa...The Songliao Basin is famous for the Daqing Oilfield, the biggest in China. However, no economic hydrocarbon reservoir has been found in the northeastern Binbei district. Its thermal history, which is of great importance for hydrocarbon generation and migration, is studied with apatite fission track (AFT) thermochronology. Samples with depositional ages of the late Cretaceous (-108-73 Ma) are analyzed. The AFT ages of the samples from reservoir rock (depositional age 〉 76.1 Ma) fall between the late Cretaceous (724-5 Ma) and the early Eocene (414-3 Ma) period, indicating their total annealing after deposition. In contrast, two samples from the main seals of the Qingshankou (depositional age 〉 89.3 Ma) and the Nenjiang Formation (depositional age 〉 73.0 Ma) are not annealed or partially annealed (AFT ages of 974-9 Ma and 704-4 Ma, respectively). Because the maximum burial temperature (〈90 ℃) evidenced by low vitrinite reflectance (Ro〈0.7) is not high enough to account for the AFT total annealing (110-120 ℃), the transient thermal effect arising from the syntectonic fluid flow between the late Cretaceous and the early Eocene is proposed. Transient thermal effects from fluid flow explains the indicated temperature discrepancies between the AFT thermometer and the Ro thermometer because the transient thermal effect from the fluid flow with a temperature high enough (110-120 ℃) to anneal the AFT thermometer does not last long enough (104-105 yrs.) for an enhancement of the Ro (minimum 106- 107 yrs. under the same temperature). This indicates that dating thermal effect from fluid flow might be a new means to reconstruct the tectonic history. It also answers why the samples from the main seals are not annealed because the seals will prohibit fluid flow and supply good thermal insulation. The large-scale fluid flow in the Binbei district calls for a new idea to direct the hydrocarbon exploration.展开更多
An improved compound mathematical model is established to simulate the attenuation of hydraulic transients with laminar-turbulent alternations,which usually occur when the pipeline flow velocity fluctuates near the cr...An improved compound mathematical model is established to simulate the attenuation of hydraulic transients with laminar-turbulent alternations,which usually occur when the pipeline flow velocity fluctuates near the critical velocity.The laminar friction resistance and the turbulent friction resistance are considered respectively in this model by applying different resistance schemes to the characteristics method of fluid transient analysis.The hydraulic transients of the valve closing process are simulated using the model.A more reasonable attenuation of hydraulic transients is obtained.The accurate attenuation is more distinct than that obtained from the traditional mathematical model.The research shows that the hydraulic transient is a type of energy waves,and its attenuation is caused by the friction resistance.The laminar friction resistance is more important than the turbulent friction resistance if the flow velocity is smaller than the critical velocity.Otherwise the turbulent friction resistance is more important.The laminar friction resistance is important in the attenuation of hydraulic transients for the closing process.Thus,it is significant to consider the different resistances separately to obtain more accurate attenuation of hydraulic transients.展开更多
The transient growth due to non-normMity is investigated for the Poiseuille- Rayleigh-Benard problem of binary fluids with the Soret effect. For negative separation factors such as ψ = -0.1, it is found that a large ...The transient growth due to non-normMity is investigated for the Poiseuille- Rayleigh-Benard problem of binary fluids with the Soret effect. For negative separation factors such as ψ = -0.1, it is found that a large transient growth can be obtained by the non-normal interaction of the two least-stable-modes, i.e., the upstream and downstream modes, which determine the linear critical boundary curves for small Reynolds numbers. The transient growth is so strong that the optimal energy amplification factor G(t) is up to 10^2 - 10^3. While for positive separation factors such as ψ = 0.1, the transient growth is weak with the order O(I) of the amplification factor, which can even be computed by the least-stable-mode. However, for both cases, the least-stable-mode can govern the long-term behavior of the amplification factor for large time. The results also show that large Reynolds numbers have stabilization effects for the maximum amplification within moderate wave number regions. Meanwhile, much small negative or large positive separation factors and large Rayleigh numbers can enlarge the maximum transient growth of the pure streamwise disturbance with the wavenumber α= 3.14. Moreover, the initial and evolutionary two-dimensional spatial patterns of the large transient growth for the pure streamwise disturbance are exhibited with a plot of the velocity vector, spanwise vorticity, temperature, and concentration field. The initial three-layer cell vorticity struc- ture is revealed. When the amplification factor reaches the maximum Gmax, it develops into one cell structure with large amplification for the vorticity strength.展开更多
A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to d...A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to describe the viscosity function with a structural parameter λ which varies according to differ- ent kinetic orders of particle aggregation and segregation. The transient stress response is obtained by solving an instantaneous Maxwell model with an assumed shear modulus function G of the same form as the viscosity function η. Accuracy of the proposed model is verified experimentally with the results obtained for two oil (creosote)/water emulsions. The model that gives the best fit of experimental data appears to be the one with kinetic orders n = m = 2.展开更多
The steady oil production and pressure distribution formulae of vertically fractured well for power-law non-Newtonian fluid were derived on the basis of the elliptic flow model in fractal reservoirs. The corresponding...The steady oil production and pressure distribution formulae of vertically fractured well for power-law non-Newtonian fluid were derived on the basis of the elliptic flow model in fractal reservoirs. The corresponding transient flow in fractal reservoirs was studied by numerical differentiation method: the influence of fractal index to transient pressure of vertically fractured well was analyzed. Finally the approximate analytical solution of transient flow was given by average mass conservation law. The study shows that using elliptic flow method to analyze the flow of vertically fractured well is a simple method.展开更多
In this paper the flow through a control directional valve is studied by means of a CFD (computational fluid-dynamics) analysis under transient operating conditions. The mesh motion is resolved on a time basis as a ...In this paper the flow through a control directional valve is studied by means of a CFD (computational fluid-dynamics) analysis under transient operating conditions. The mesh motion is resolved on a time basis as a function of the external actuation system In the analysis, an open source fluid-dynamics code is used and both cavitation and turbulence are accounted for in the modeling. Moreover, the numerical model of the working fluid is modified in order to account also for the non-Newtonian fluids. The effects of the shear rate on the shear stress are accounted for both by using experimental measurements and correlations available in literature, such as the Herschel-Bulkley model. The analysis determines the performance of the control directional valve under different operating conditions when using either Newtonian or non-Newtonian fluids. In particular, the discharge coefficient, the recirculating regions, the flow acceleration angle and the pressure and velocity fields are investigated.展开更多
One-dimensional nuclear magnetic resonance (1D NMR) logging technology is limited for fluid typing, while two-dimensional nuclear magnetic resonance (2D NMR) logging can provide more parameters including longitudi...One-dimensional nuclear magnetic resonance (1D NMR) logging technology is limited for fluid typing, while two-dimensional nuclear magnetic resonance (2D NMR) logging can provide more parameters including longitudinal relaxation time (71) and transverse relaxation time (T2) relative to fluid types in porous media. Based on the 2D NMR relaxation mechanism in a gradient magnetic field, echo train simulation and 2D NMR inversion are discussed in detail. For 2D NMR inversion, a hybrid inversion method is proposed based on the damping least squares method (LSQR) and an improved truncated singular value decomposition (TSVD) algorithm. A series of spin echoes are first simulated with multiple waiting times (Tws) in a gradient magnetic field for given fluid models and these synthesized echo trains are inverted by the hybrid method. The inversion results are consistent with given models. Moreover, the numerical simulation of various fluid models such as the gas-water, light oil-water, and vicious oil-water models were carried out with different echo spacings (TEs) and Tws by this hybrid method. Finally, the influences of different signal-to-noise ratios (SNRs) on inversion results in various fluid models are studied. The numerical simulations show that the hybrid method and optimized observation parameters are applicable to fluid typing of gas-water and oil-water models.展开更多
文摘This paper proposes a lattice Boltzmann scheme to simulate two-dimensionalfluid transients. A set of multi-scale equations, which characterize the relations between thelattice Boltzmann equation and its corresponding macroscopic equations, were derived by using theChapman-Enskog expansion. Based on these multi-scale equations and the basic equations ofmultidimensional fluid transients, two special lattice Boltzmann models were established. Numericalsimulation of one-dimensional pressure wave transmission and reflection, two-dimensional wave cornerdiffraction and hydraulic transients in a concrete spiral case show that the Lattice BoltzmannMethod (LBM) is a feasible and promising approach to simulate multidimensional transient flows.
基金Project supported by the National Natural Science Foundation of China (No. 10272051).
文摘The chaotic transients of a curved fluid conveying tube subjected to a nonlinear foundation are investigated. The assumption of the inextensibility of the tube is applied to derive the nonlinear differential equation of motion via the Newtonian approach, with the differential quadrature method used to discretize the curved tube model in the spatial domain. And the nonlinear dynamic motion equation is obtained. The numerical analysis shows that, the final steady states are sensitive to the initial system conditions in a large parameter region of the fluid speed. This phenomenon of chaotic transients is infrequent for fluid conveying tubes.
基金Project supported by the Natural Science Foundation of Liaoning Province,China (Grant No. 201102181)
文摘A new approach of generating transient chaos from two-dimensional(2D) continuous autonomous systems within finite time is presented.Based on an absolute-value switching law,the phenomenon of transient chaos takes place by switching between three 2D systems.Basic dynamic behavior of the systems is investigated.Numerical examples illustrate the validity of the results.
基金This work is supported by the National Natural Science Foundation of China(No.52104049)the Young Elite Scientist Sponsorship Program by Beijing Association for Science and Technology(No.BYESS2023262)Science Foundation of China University of Petroleum,Beijing(No.2462022BJRC004).
文摘Polymer flooding in fractured wells has been extensively applied in oilfields to enhance oil recovery.In contrast to water,polymer solution exhibits non-Newtonian and nonlinear behavior such as effects of shear thinning and shear thickening,polymer convection,diffusion,adsorption retention,inaccessible pore volume and reduced effective permeability.Meanwhile,the flux density and fracture conductivity along the hydraulic fracture are generally non-uniform due to the effects of pressure distribution,formation damage,and proppant breakage.In this paper,we present an oil-water two-phase flow model that captures these complex non-Newtonian and nonlinear behavior,and non-uniform fracture characteristics in fractured polymer flooding.The hydraulic fracture is firstly divided into two parts:high-conductivity fracture near the wellbore and low-conductivity fracture in the far-wellbore section.A hybrid grid system,including perpendicular bisection(PEBI)and Cartesian grid,is applied to discrete the partial differential flow equations,and the local grid refinement method is applied in the near-wellbore region to accurately calculate the pressure distribution and shear rate of polymer solution.The combination of polymer behavior characterizations and numerical flow simulations are applied,resulting in the calculation for the distribution of water saturation,polymer concentration and reservoir pressure.Compared with the polymer flooding well with uniform fracture conductivity,this non-uniform fracture conductivity model exhibits the larger pressure difference,and the shorter bilinear flow period due to the decrease of fracture flow ability in the far-wellbore section.The field case of the fall-off test demonstrates that the proposed method characterizes fracture characteristics more accurately,and yields fracture half-lengths that better match engineering reality,enabling a quantitative segmented characterization of the near-wellbore section with high fracture conductivity and the far-wellbore section with low fracture conductivity.The novelty of this paper is the analysis of pressure performances caused by the fracture dynamics and polymer rheology,as well as an analysis method that derives formation and fracture parameters based on the pressure and its derivative curves.
文摘The algebraic solitary wave and its associated eigenvalue problem in a deep stratified fluid with a free surface and a shallow upper layer were studied. And its vertical structure was examined. An exact solution for the derived 2D Benjamin-Ono equation was obtained, and physical explanation was given with the corresponding dispersion relation. As a special case, the vertical structure of the weakly nonlinear internal wave for the Holmboe density distribution was numerically investigated, and the propagating mechanism of the internal wave was studied by using the ray theory.
文摘This paper presents the analytical solutions in Laplace domain for two-dimensional nonsteady flow of slightly compressible liquid in porous media with double porosity by using the methods of integral transforms and variables separation. The effects of the ratio of storativities to , interporosity flow parameter on the pressure behaviors for a vertically fractured well with infinite conductivity are investigated by using the method of numerical inversion. The new log-log diagnosis graph of the pressures is given and analysed.
基金the National Natural Science Foundation of China, No.30370499
文摘BACKGROUND: Previous studies have confirmed the existence of specific proteins in body fluid of Parkinson's disease (PD) patients. However, the existing research has contained several interference factors with poor reproducibility and has not focused on patients grouped according to disease duration. OBJECTIVE: To verify differential expression of proteins in cerebrospinal fluid of PD patients grouped in order of disease severity through the use of two-dimensional electrophoresis-mass spectrometry methods. DESIGN, TIME AND SETTING: The proteomic-based, case-control study was performed between September 2008 and June 2009 at the Key Laboratory of Neurology in the First Affiliated Hospital of Chongqing Medical University. PARTICIPANTS: A total of 52 outpatients and/or inpatients, who were admitted to the Department of Neurology in the First Affiliated Hospital of Chongqing Medical University between 2008 and 2009, were randomized into the present study. Among them, 27 PD patients served as the PD group and were assigned to three subgroups according to modified Webster, Hoehn, and Yahr rating scales: 14 = mild, 8 = moderate, and 5 = severe; non-PD group of 16 patients included 5 cases of viral meningitis, 3 cases of acute myelitis, 1 case of Guillain-Barre syndrome, 2 cases of tuberculous meningitis, 2 cases of restless legs syndrome, and 3 cases of essential tremor; control group (n = 9) consisted of muscular tension headache in 6 cases, as well as syncope, trigeminal neuralgia, idiopathic orthostatic hypotension in 1 case. METHODS: Cerebrospinal fluid was collected from the involved patients using the lumbar puncture method. Proteins in the cerebrospinal fluid were separated by two-dimensional electrophoresis. MAIN OUTCOME MEASURES: Characteristics of protein electrophoresis patterns were analyzed, differentially expressed proteins were detected using matrix-assisted laser desorption ionization time of flight mass spectrometry, and protein data were analyzed in the Mascot database. RESULTS: Five protein electropherograms were analyzed by PDQuest 8.0, and (789 ± 32) protein spots were observed. There were significant differences in four protein spots in each of the PD sub-groups compared with the non-disease and control groups. Expression was down-regulated in three protein spots and up-regulated in one protein spot; 100% repetition rate was observed in four protein spots. According to the Mascot database, protein spots with down-regulated expression were as follows: DNA-guided RNA polymerase III subunit RPC5 (score: 50 points); double serine, threonine, and tyrosine protein kinase (score: 64 points, P 〈 0.05); activity-regulated cytoskeleton-associated protein (score: 58 points, P 〈 0.05). However, G2 mitotic-specific cyclin was up-regulated (score: 84 points, P 〈 0.05). CONCLUSION: Differential protein expression in the cerebrospinal fluid of PD patients was detected by two-dimensional electrophoresis-mass spectrometry, revealing changes in DNA-guided RNA polymerase III subunit RPC5, double serine, threonine, and tyrosine protein kinase, activity-regulated cytoskeleton-associated protein, and G2 mitotic cell cyclin, with good reproducibility.
文摘A theoretical equation is developed which describes the response of the current transients to a constant potential at tubular electrodes for a reversible electrode reaction in the flowing fluid.
文摘The transient Rayleigh wave exploration has high detection accuracy in shallow exploration. The effect of detection array is comprehensive reflection of the velocity of rock and soil mass. Therefore, the roiling multi-channel transient acquisition system has been adopted in this study, which turns one dimensional transient Rayleigh wave exploration into two dimensions, consequently, the two-dimensional velocity distribution of rock and soil mass under the survey line has been achieved. Through comparing with the shallow seismic reflected wave exploration, the result indicates that the rolling multi-channel transient acquisition system has accurate resolution. Thus, in the process of the shallow reflected wave exploration, if the surface wave has developed, the coalition between the reflected wave exploration and the two-dimensional transient Rayleigh wave exploration should actualize the accuracy of exploration.
基金supported by National Hi-tech Research and Development Program of China (863 Program, Grant No. 2009AA04Z413)Zhejiang Provincial Natural Science Foundation of China (Grant No. Y1110109)
文摘Journal bearings are important parts to keep the high dynamic performance of rotor machinery. Some methods have already been proposed to analysis the flow field of journal bearings, and in most of these methods simplified physical model and classic Reynolds equation are always applied. While the application of the general computational fluid dynamics (CFD)-fluid structure interaction (FSI) techniques is more beneficial for analysis of the fluid field in a journal bearing when more detailed solutions are needed. This paper deals with the quasi-coupling calculation of transient fluid dynamics of oil film in journal bearings and rotor dynamics with CFD-FSI techniques. The fluid dynamics of oil film is calculated by applying the so-called "dynamic mesh" technique. A new mesh movement approacb is presented while the dynamic mesh models provided by FLUENT are not suitable for the transient oil flow in journal bearings. The proposed mesh movement approach is based on the structured mesh. When the joumal moves, the movement distance of every grid in the flow field of bearing can be calculated, and then the update of the volume mesh can be handled automatically by user defined function (UDF). The journal displacement at each time step is obtained by solving the moving equations of the rotor-bearing system under the known oil film force condition. A case study is carried out to calculate the locus of the journal center and pressure distribution of the journal in order to prove the feasibility of this method. The calculating results indicate that the proposed method can predict the transient flow field of a journal bearing in a rotor-bearing system where more realistic models are involved. The presented calculation method provides a basis for studying the nonlinear dynamic behavior of a general rotor-bearing system.
基金supported by the National Natural Science Foundation of China (Grant Nos.40872097 and 41272161)the Major National Science & Technology Program (Grant Nos.2011ZX05006-005 and 2011ZX05006-006)partly funded by the State Key Laboratory for Petroleum Resource and Prospecting (Grant No.KYJJ2012-01-12)
文摘The Songliao Basin is famous for the Daqing Oilfield, the biggest in China. However, no economic hydrocarbon reservoir has been found in the northeastern Binbei district. Its thermal history, which is of great importance for hydrocarbon generation and migration, is studied with apatite fission track (AFT) thermochronology. Samples with depositional ages of the late Cretaceous (-108-73 Ma) are analyzed. The AFT ages of the samples from reservoir rock (depositional age 〉 76.1 Ma) fall between the late Cretaceous (724-5 Ma) and the early Eocene (414-3 Ma) period, indicating their total annealing after deposition. In contrast, two samples from the main seals of the Qingshankou (depositional age 〉 89.3 Ma) and the Nenjiang Formation (depositional age 〉 73.0 Ma) are not annealed or partially annealed (AFT ages of 974-9 Ma and 704-4 Ma, respectively). Because the maximum burial temperature (〈90 ℃) evidenced by low vitrinite reflectance (Ro〈0.7) is not high enough to account for the AFT total annealing (110-120 ℃), the transient thermal effect arising from the syntectonic fluid flow between the late Cretaceous and the early Eocene is proposed. Transient thermal effects from fluid flow explains the indicated temperature discrepancies between the AFT thermometer and the Ro thermometer because the transient thermal effect from the fluid flow with a temperature high enough (110-120 ℃) to anneal the AFT thermometer does not last long enough (104-105 yrs.) for an enhancement of the Ro (minimum 106- 107 yrs. under the same temperature). This indicates that dating thermal effect from fluid flow might be a new means to reconstruct the tectonic history. It also answers why the samples from the main seals are not annealed because the seals will prohibit fluid flow and supply good thermal insulation. The large-scale fluid flow in the Binbei district calls for a new idea to direct the hydrocarbon exploration.
基金supported by the National Natural Science Foundation of China (No 50709029)the Key Special Program on the Science and Technology of China for the Pollution Control and Treatment of Water Bodies (No 2009ZX07424-004)
文摘An improved compound mathematical model is established to simulate the attenuation of hydraulic transients with laminar-turbulent alternations,which usually occur when the pipeline flow velocity fluctuates near the critical velocity.The laminar friction resistance and the turbulent friction resistance are considered respectively in this model by applying different resistance schemes to the characteristics method of fluid transient analysis.The hydraulic transients of the valve closing process are simulated using the model.A more reasonable attenuation of hydraulic transients is obtained.The accurate attenuation is more distinct than that obtained from the traditional mathematical model.The research shows that the hydraulic transient is a type of energy waves,and its attenuation is caused by the friction resistance.The laminar friction resistance is more important than the turbulent friction resistance if the flow velocity is smaller than the critical velocity.Otherwise the turbulent friction resistance is more important.The laminar friction resistance is important in the attenuation of hydraulic transients for the closing process.Thus,it is significant to consider the different resistances separately to obtain more accurate attenuation of hydraulic transients.
基金Project supported by the National Natural Science Foundation of China(Nos.11172049 and11472060)
文摘The transient growth due to non-normMity is investigated for the Poiseuille- Rayleigh-Benard problem of binary fluids with the Soret effect. For negative separation factors such as ψ = -0.1, it is found that a large transient growth can be obtained by the non-normal interaction of the two least-stable-modes, i.e., the upstream and downstream modes, which determine the linear critical boundary curves for small Reynolds numbers. The transient growth is so strong that the optimal energy amplification factor G(t) is up to 10^2 - 10^3. While for positive separation factors such as ψ = 0.1, the transient growth is weak with the order O(I) of the amplification factor, which can even be computed by the least-stable-mode. However, for both cases, the least-stable-mode can govern the long-term behavior of the amplification factor for large time. The results also show that large Reynolds numbers have stabilization effects for the maximum amplification within moderate wave number regions. Meanwhile, much small negative or large positive separation factors and large Rayleigh numbers can enlarge the maximum transient growth of the pure streamwise disturbance with the wavenumber α= 3.14. Moreover, the initial and evolutionary two-dimensional spatial patterns of the large transient growth for the pure streamwise disturbance are exhibited with a plot of the velocity vector, spanwise vorticity, temperature, and concentration field. The initial three-layer cell vorticity struc- ture is revealed. When the amplification factor reaches the maximum Gmax, it develops into one cell structure with large amplification for the vorticity strength.
文摘A phenomenological model for dispersed systems which exhibit complex theological behaviour such as shear and time-dependent viscosity, yield stress, and elasticity is proposed. The model extends the Quemeda model to describe the viscosity function with a structural parameter λ which varies according to differ- ent kinetic orders of particle aggregation and segregation. The transient stress response is obtained by solving an instantaneous Maxwell model with an assumed shear modulus function G of the same form as the viscosity function η. Accuracy of the proposed model is verified experimentally with the results obtained for two oil (creosote)/water emulsions. The model that gives the best fit of experimental data appears to be the one with kinetic orders n = m = 2.
文摘The steady oil production and pressure distribution formulae of vertically fractured well for power-law non-Newtonian fluid were derived on the basis of the elliptic flow model in fractal reservoirs. The corresponding transient flow in fractal reservoirs was studied by numerical differentiation method: the influence of fractal index to transient pressure of vertically fractured well was analyzed. Finally the approximate analytical solution of transient flow was given by average mass conservation law. The study shows that using elliptic flow method to analyze the flow of vertically fractured well is a simple method.
文摘In this paper the flow through a control directional valve is studied by means of a CFD (computational fluid-dynamics) analysis under transient operating conditions. The mesh motion is resolved on a time basis as a function of the external actuation system In the analysis, an open source fluid-dynamics code is used and both cavitation and turbulence are accounted for in the modeling. Moreover, the numerical model of the working fluid is modified in order to account also for the non-Newtonian fluids. The effects of the shear rate on the shear stress are accounted for both by using experimental measurements and correlations available in literature, such as the Herschel-Bulkley model. The analysis determines the performance of the control directional valve under different operating conditions when using either Newtonian or non-Newtonian fluids. In particular, the discharge coefficient, the recirculating regions, the flow acceleration angle and the pressure and velocity fields are investigated.
基金sponsored by the National Natural Science Foundation of China(41172130)the Fundamental Research Funds for the Central Universities(2-9-2012-48)+1 种基金the National Major Projects(No.2011ZX05014-001)CNPC Innovation Foundation(No.2011D-5006-0305)
文摘One-dimensional nuclear magnetic resonance (1D NMR) logging technology is limited for fluid typing, while two-dimensional nuclear magnetic resonance (2D NMR) logging can provide more parameters including longitudinal relaxation time (71) and transverse relaxation time (T2) relative to fluid types in porous media. Based on the 2D NMR relaxation mechanism in a gradient magnetic field, echo train simulation and 2D NMR inversion are discussed in detail. For 2D NMR inversion, a hybrid inversion method is proposed based on the damping least squares method (LSQR) and an improved truncated singular value decomposition (TSVD) algorithm. A series of spin echoes are first simulated with multiple waiting times (Tws) in a gradient magnetic field for given fluid models and these synthesized echo trains are inverted by the hybrid method. The inversion results are consistent with given models. Moreover, the numerical simulation of various fluid models such as the gas-water, light oil-water, and vicious oil-water models were carried out with different echo spacings (TEs) and Tws by this hybrid method. Finally, the influences of different signal-to-noise ratios (SNRs) on inversion results in various fluid models are studied. The numerical simulations show that the hybrid method and optimized observation parameters are applicable to fluid typing of gas-water and oil-water models.