Two-dimensional(2D) materials have been regarded as a promising nonlinear optical medium for fabricating versatile optical and optoelectronic devices. Among the various photonic applications, the employment of 2D ma...Two-dimensional(2D) materials have been regarded as a promising nonlinear optical medium for fabricating versatile optical and optoelectronic devices. Among the various photonic applications, the employment of 2D materials as nonlinear optical devices such as saturable absorbers for ultrashort pulse generation and shaping in ultrafast lasers is one of the most striking aspects in recent years. In this paper, we review the recent progress of 2D materials based pulse generation and soliton shaping in ultrafast fiber lasers, and particularly in the context of 2D materials-decorated microfiber photonic devices. The fabrication of 2D materials-decorated microfiber photonic devices, high performance mode-locked pulse generation, and the nonlinear soliton dynamics based on pulse shaping method are discussed. Finally, the challenges and the perspective of the 2D materials-based photonic devices as well as their applications are also discussed.展开更多
Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time, expression amount, protein post-translational processing or modif...Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time, expression amount, protein post-translational processing or modification. Therefore, it is necessary to quantitatively analyze the gene expression profile using proteomic techniques. In the present study, we established a rat model of closed brain injury using Marmarou's weight-drop device, and investigated hippocampal differential protein expression using two-dimensional gel electrophoresis and surface-enhanced laser desorption ionization-time of flight-mass spectrometry. A total of 364 protein peaks were detected on weak cation exchange-2 protein chips, including 37 differential protein peaks. 345 protein peaks were detected on immobilized metal affinity capture arrays-Cu, including 12 differential protein peaks Further examination of these differential proteins revealed that glucose-regulated protein and proteasome subunit alpha type 3 expression were significantly upregulated post-injury. These results indicate that brain injury can alter protein expression in the hippocampus, and that glucose-regulated protein and proteasome subunit alpha type 3 are closely associated with the occurrence and development of traumatic brain injury.展开更多
The angular spectrum of spontaneous emission in a two-dimensional undulator free-electron laser is analyzed theoretically. Numerical calculation shows that the 3-th harmonic spontaneous emission power density can be g...The angular spectrum of spontaneous emission in a two-dimensional undulator free-electron laser is analyzed theoretically. Numerical calculation shows that the 3-th harmonic spontaneous emission power density can be greatly enhanced by using a two-dimensional undulator, for which l=s, so the harmonic number can be selected by selecting l. Therefore, the higher harmonic operation of a free-electron laser can be realized selectively.展开更多
A two-dimensional silver nanoplate is prepared with the seed-mediated growth method and is used for achieving pulse fiber laser operation. By controlling the dimension parameters of the silver nanoplate, the surface p...A two-dimensional silver nanoplate is prepared with the seed-mediated growth method and is used for achieving pulse fiber laser operation. By controlling the dimension parameters of the silver nanoplate, the surface plasmon resonance absorption peak of the material is successfully adjusted to 1068 nm. Based on the silver nanoplate as a saturable absorber, a passively Q-switched Yb-doped fiber laser operating at 1062 nm is demonstrated. The maximum average output power of 3.49mW is obtained with a minimum pulse width of 1.84#s at a pulse repetition rate of 65.TkHz, and the corresponding pulse energy and peak power are 53.1 nJ and 28.8mW, respectively.展开更多
Direct-write atom lithography,one of the potential nanofabrication techniques,is restricted by some difficulties in producing optical masks for the deposition of complex structures.In order to make further progress,a ...Direct-write atom lithography,one of the potential nanofabrication techniques,is restricted by some difficulties in producing optical masks for the deposition of complex structures.In order to make further progress,a structured mirror array is developed to transversely collimate the chromium atomic beam in two dimensions.The best collimation is obtained when the laser red detunes by natural line-width of transition 7S3 → 7P40 of the chromium atom.The collimation ratio is 0.45 vertically(in x axis),and it is 0.55 horizontally(in y axis).The theoretical model is also simulated,and success of our structured mirror array is achieved.展开更多
The digital communication of two-dimensional messages is investigated when two solid state multi-mode chaotic lasers are employed in a master-slave configuration. By introducing the time derivative of intensity differ...The digital communication of two-dimensional messages is investigated when two solid state multi-mode chaotic lasers are employed in a master-slave configuration. By introducing the time derivative of intensity difference between the receiver (carrier) and the transmittal (carrier plus signal), several signals can be encoded into a single pulse. If one signal contains several binary bits, two-dimensional messages in the form of a matrix can be encoded and transmitted on a single pulse. With these improvements in secure communications using chaotic multi-mode lasers, not only the transmission rate can be increased but also the privacy can be enhanced greatly.展开更多
A method of studying a non-equilibrium x-ray laser plasma is developed by extending the existing one-dimensional similarity equations to the case of two-dimensional plasma study in the directions perpendicular to the ...A method of studying a non-equilibrium x-ray laser plasma is developed by extending the existing one-dimensional similarity equations to the case of two-dimensional plasma study in the directions perpendicular to the slab and along a focal line. With this method the characteristics of pre-plasma are optimized for transient neon-like Cr x-ray laser. It is found that when the duration and the intensity of 1.053μm pre-pulse are 1.2 ns and 6.5 TW/cm^2 respectively with a delay time of 1.5 ns, the temperature and the temperature discrepancy each approach a proper state, which will provide a uniform distribution of properly ionized neon-like Cr ions before the arrival of pumping pulse.展开更多
Space radiation with inherently broadband spectral flux poses a huge danger to astronauts and electronics on aircraft,but it is hard to simulate such feature with conventional radiation sources. Using a tabletop laser...Space radiation with inherently broadband spectral flux poses a huge danger to astronauts and electronics on aircraft,but it is hard to simulate such feature with conventional radiation sources. Using a tabletop laser-plasma accelerator, we can reproduce exponential energy particle beams as similar as possible to these in space radiation. We used such an electron beam to study the electron radiation effects on the surface structure and performance of two-dimensional material(Fe PS3).Energetic electron beam led to bulk sample cleavage and damage between areas of uneven thickness. For the Fe PS3sheet sample, electron radiation transformed it from crystalline state to amorphous state, causing the sample surface to rough.The full widths at the half maximum of characteristic Raman peaks became larger, and the intensities of characteristic Raman peaks became weak or even disappeared dramatically under electron radiation. This trend became more obvious for thinner samples, and this phenomenon was attributed to the cleavage of P–P and P–S bonds, destabilizing the bipyramid structure of [P2S6]4-unit. The results are of great significance for testing the maximum allowable radiation dose for the two-dimensional material, implying that Fe PS3cannot withstand such energetic electron radiation without an essential shield.展开更多
Objective: The aim of this study was to establish reproducible two-dimensional electrophoretic assay used for profiling and identification of differentially expressed proteins in human stage I lung adenocarcinoma and...Objective: The aim of this study was to establish reproducible two-dimensional electrophoretic assay used for profiling and identification of differentially expressed proteins in human stage I lung adenocarcinoma and paired normal tumor-adjacent tissue. Methods: The proteins from 12 human stage I lung adenocarcinoma tissues and normal tumor-adjacent tissues were separated using isoelectric focusing electrophoresis (the first dimension) and the subsequent homogeneous SDS-polyacrylamide gel electrophoresis (SDS-PAGE) (the second dimension). The differentially expressed proteins were determined with PDQuest image analysis software, and identified using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) and database searching. Results: The well-reproducible 2-DE gel patterns of human stage I lung adenocarcinoma and normal tumor-adjacent tissues were profiled and 26 differentially expressed proteins uncovered. Nine of these 26 protein spots were cut out from the preparation gels and determined with MALDI-TOF-MS. Searching against the protein database, four candidate proteins were identified. They were 60S acidic ribosomal protein P2, Cathepsin B1, Apolipoprotein A-I precursor, and La 4.1 protein. Conclusion: In this study, high reproducible 2-DE gel protein images of human stage I lung adenocarcinoma and paired normal tumor-adjacent tissues were achieved successfully, and 4 differentially expressed proteins were revealed. These data will be helpful for screen of early biomarker and study of molecular mechanisms of human lung adenocarcinoma.展开更多
<span style="font-family:Verdana;">T</span><span style="font-family:Verdana;font-size:12px;">he T</span><span style="font-family:Verdana;font-size:12px;">i&l...<span style="font-family:Verdana;">T</span><span style="font-family:Verdana;font-size:12px;">he T</span><span style="font-family:Verdana;font-size:12px;">i</span><span style="font-family:Verdana;font-size:12px;">Se</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">nanosheets</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">were</span><span style="font-family:Verdana;font-size:12px;"> prepared by means of ultrasound-assisted liquid </span><span style="font-family:Verdana;font-size:12px;">phase exfoliation (LPE)</span><span style="font-family:Verdana;font-size:12px;"> and the </span><span style="font-family:Verdana;font-size:12px;">nonlinear </span><span style="font-family:Verdana;font-size:12px;">saturable absorption</span><span style="font-family:Verdana;font-size:12px;"> properties</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">were experimentally</span><span style="font-family:Verdana;font-size:12px;"> investigated. The modulation depth, saturation intensity and nonsaturable absorbance</span><span style="font-family:Verdana;font-size:12px;"> of the prepared </span><span style="font-family:Verdana;font-size:12px;">1T-TiSe</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">SA </span><span style="font-family:Verdana;font-size:12px;">were</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">1</span><span style="font-family:Verdana;font-size:12px;">5.7</span><span style="font-family:Verdana;font-size:12px;">%,</span><span style="font-family:Verdana;font-size:12px;"> 1.28 M</span><span style="font-family:Verdana;font-size:12px;">W/cm</span><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and 8.</span><span style="font-family:Verdana;font-size:12px;">2</span><span style="font-family:Verdana;font-size:12px;">%, </span><span style="font-family:Verdana;font-size:12px;">respectively</span><span style="font-family:Verdana;font-size:12px;">. Taking advantage of the saturable absorption properties of </span><span style="font-family:Verdana;font-size:12px;">T</span><span style="font-family:Verdana;font-size:12px;">i</span><span style="font-family:Verdana;font-size:12px;">Se</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;">-based SA, a passively Q-switched erbium-doped fiber (EDF) laser was</span><span style="font-family:Verdana;font-size:12px;"> systematically demonstrated</span><span style="font-family:Verdana;font-size:12px;">. The pulse repetition rates varied from 24.50 kHz up to 73.79 kHz with the increasing pump power. The obtained shortest pulse width was 1.31 </span><span style="font-family:Verdana;font-size:12px;">μ</span><span style="font-family:Verdana;font-size:12px;">s with pulse energy of 79.28 nJ. The </span><span style="font-family:Verdana;font-size:12px;">system presented merits of low-cost SA preparation, system compactness,</span><span style="font-family:Verdana;font-size:12px;"> superb stability and high competition.</span>展开更多
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61307058,61378036,11304101,and 11474108)Guangdong Natural Science Funds for Distinguished Young Scholar,China(Grant No.2014A030306019)+6 种基金Pearl River S&T Nova Program of Guangzhou,China(Grant No.2014J2200008)Program for Outstanding Innovative Young Talents of Guangdong Province,China(Grant No.2014TQ01X220)Program for Outstanding Young Teachers in Guangdong Higher Education Institutes,China(Grant No.YQ2015051)Science and Technology Project of Guangdong,China(Grant No.2016B090925004)Foundation for Young Talents in Higher Education of Guangdong,China(Grant No.2017KQNCX051)Science and Technology Program of Guangzhou,China(Grant No.201607010245)Scientific Research Foundation of Young Teacher of South China Normal University,China(Grant No.17KJ09)
文摘Two-dimensional(2D) materials have been regarded as a promising nonlinear optical medium for fabricating versatile optical and optoelectronic devices. Among the various photonic applications, the employment of 2D materials as nonlinear optical devices such as saturable absorbers for ultrashort pulse generation and shaping in ultrafast lasers is one of the most striking aspects in recent years. In this paper, we review the recent progress of 2D materials based pulse generation and soliton shaping in ultrafast fiber lasers, and particularly in the context of 2D materials-decorated microfiber photonic devices. The fabrication of 2D materials-decorated microfiber photonic devices, high performance mode-locked pulse generation, and the nonlinear soliton dynamics based on pulse shaping method are discussed. Finally, the challenges and the perspective of the 2D materials-based photonic devices as well as their applications are also discussed.
基金the National Natural Science Foundation of China,No. 30471934
文摘Gene expression profile changes in brain regions following traumatic brain injury at the gene level cannot sufficiently elucidate gene expression time, expression amount, protein post-translational processing or modification. Therefore, it is necessary to quantitatively analyze the gene expression profile using proteomic techniques. In the present study, we established a rat model of closed brain injury using Marmarou's weight-drop device, and investigated hippocampal differential protein expression using two-dimensional gel electrophoresis and surface-enhanced laser desorption ionization-time of flight-mass spectrometry. A total of 364 protein peaks were detected on weak cation exchange-2 protein chips, including 37 differential protein peaks. 345 protein peaks were detected on immobilized metal affinity capture arrays-Cu, including 12 differential protein peaks Further examination of these differential proteins revealed that glucose-regulated protein and proteasome subunit alpha type 3 expression were significantly upregulated post-injury. These results indicate that brain injury can alter protein expression in the hippocampus, and that glucose-regulated protein and proteasome subunit alpha type 3 are closely associated with the occurrence and development of traumatic brain injury.
文摘The angular spectrum of spontaneous emission in a two-dimensional undulator free-electron laser is analyzed theoretically. Numerical calculation shows that the 3-th harmonic spontaneous emission power density can be greatly enhanced by using a two-dimensional undulator, for which l=s, so the harmonic number can be selected by selecting l. Therefore, the higher harmonic operation of a free-electron laser can be realized selectively.
基金Supported by the Foundation of Shandong Province under Grant No J13LN28the National Natural Science Foundation of China under Grant No 11304184
文摘A two-dimensional silver nanoplate is prepared with the seed-mediated growth method and is used for achieving pulse fiber laser operation. By controlling the dimension parameters of the silver nanoplate, the surface plasmon resonance absorption peak of the material is successfully adjusted to 1068 nm. Based on the silver nanoplate as a saturable absorber, a passively Q-switched Yb-doped fiber laser operating at 1062 nm is demonstrated. The maximum average output power of 3.49mW is obtained with a minimum pulse width of 1.84#s at a pulse repetition rate of 65.TkHz, and the corresponding pulse energy and peak power are 53.1 nJ and 28.8mW, respectively.
基金Project supported by the Shanghai Nanoscience Foundation,China (Grant Nos. 0852nm07000 and 0952nm07000)the National Natural Science Foundation of China (Grant Nos. 10804084 and 91123022)+1 种基金the National Key Technology R & D Program,China (Grant No. 2006BAF06B08)the Specialized Research Fund for the Doctoral Program of Ministry of High Education of China (Grant No. 200802471008)
文摘Direct-write atom lithography,one of the potential nanofabrication techniques,is restricted by some difficulties in producing optical masks for the deposition of complex structures.In order to make further progress,a structured mirror array is developed to transversely collimate the chromium atomic beam in two dimensions.The best collimation is obtained when the laser red detunes by natural line-width of transition 7S3 → 7P40 of the chromium atom.The collimation ratio is 0.45 vertically(in x axis),and it is 0.55 horizontally(in y axis).The theoretical model is also simulated,and success of our structured mirror array is achieved.
基金Project supported by the Natural Science Foundation of Jiangsu Province, China (Grant No BK2001138).
文摘The digital communication of two-dimensional messages is investigated when two solid state multi-mode chaotic lasers are employed in a master-slave configuration. By introducing the time derivative of intensity difference between the receiver (carrier) and the transmittal (carrier plus signal), several signals can be encoded into a single pulse. If one signal contains several binary bits, two-dimensional messages in the form of a matrix can be encoded and transmitted on a single pulse. With these improvements in secure communications using chaotic multi-mode lasers, not only the transmission rate can be increased but also the privacy can be enhanced greatly.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 10474137,10874242 and 10775018)the National Basic Research Program of China (Grant No 2007CB815105)the Specialized Research Fund for the DoctoralProgram of Higher Education of China (Grant No 20070290008)
文摘A method of studying a non-equilibrium x-ray laser plasma is developed by extending the existing one-dimensional similarity equations to the case of two-dimensional plasma study in the directions perpendicular to the slab and along a focal line. With this method the characteristics of pre-plasma are optimized for transient neon-like Cr x-ray laser. It is found that when the duration and the intensity of 1.053μm pre-pulse are 1.2 ns and 6.5 TW/cm^2 respectively with a delay time of 1.5 ns, the temperature and the temperature discrepancy each approach a proper state, which will provide a uniform distribution of properly ionized neon-like Cr ions before the arrival of pumping pulse.
基金Project supported by the National Natural Science Foundation of China(Grant No.11975308)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDA25050200)Science Challenge Project(Grant No.TZ2018001)。
文摘Space radiation with inherently broadband spectral flux poses a huge danger to astronauts and electronics on aircraft,but it is hard to simulate such feature with conventional radiation sources. Using a tabletop laser-plasma accelerator, we can reproduce exponential energy particle beams as similar as possible to these in space radiation. We used such an electron beam to study the electron radiation effects on the surface structure and performance of two-dimensional material(Fe PS3).Energetic electron beam led to bulk sample cleavage and damage between areas of uneven thickness. For the Fe PS3sheet sample, electron radiation transformed it from crystalline state to amorphous state, causing the sample surface to rough.The full widths at the half maximum of characteristic Raman peaks became larger, and the intensities of characteristic Raman peaks became weak or even disappeared dramatically under electron radiation. This trend became more obvious for thinner samples, and this phenomenon was attributed to the cleavage of P–P and P–S bonds, destabilizing the bipyramid structure of [P2S6]4-unit. The results are of great significance for testing the maximum allowable radiation dose for the two-dimensional material, implying that Fe PS3cannot withstand such energetic electron radiation without an essential shield.
基金Supported by a grant from the National Natural Sciences Foundation of China (No.30571552)
文摘Objective: The aim of this study was to establish reproducible two-dimensional electrophoretic assay used for profiling and identification of differentially expressed proteins in human stage I lung adenocarcinoma and paired normal tumor-adjacent tissue. Methods: The proteins from 12 human stage I lung adenocarcinoma tissues and normal tumor-adjacent tissues were separated using isoelectric focusing electrophoresis (the first dimension) and the subsequent homogeneous SDS-polyacrylamide gel electrophoresis (SDS-PAGE) (the second dimension). The differentially expressed proteins were determined with PDQuest image analysis software, and identified using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) and database searching. Results: The well-reproducible 2-DE gel patterns of human stage I lung adenocarcinoma and normal tumor-adjacent tissues were profiled and 26 differentially expressed proteins uncovered. Nine of these 26 protein spots were cut out from the preparation gels and determined with MALDI-TOF-MS. Searching against the protein database, four candidate proteins were identified. They were 60S acidic ribosomal protein P2, Cathepsin B1, Apolipoprotein A-I precursor, and La 4.1 protein. Conclusion: In this study, high reproducible 2-DE gel protein images of human stage I lung adenocarcinoma and paired normal tumor-adjacent tissues were achieved successfully, and 4 differentially expressed proteins were revealed. These data will be helpful for screen of early biomarker and study of molecular mechanisms of human lung adenocarcinoma.
文摘<span style="font-family:Verdana;">T</span><span style="font-family:Verdana;font-size:12px;">he T</span><span style="font-family:Verdana;font-size:12px;">i</span><span style="font-family:Verdana;font-size:12px;">Se</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">nanosheets</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">were</span><span style="font-family:Verdana;font-size:12px;"> prepared by means of ultrasound-assisted liquid </span><span style="font-family:Verdana;font-size:12px;">phase exfoliation (LPE)</span><span style="font-family:Verdana;font-size:12px;"> and the </span><span style="font-family:Verdana;font-size:12px;">nonlinear </span><span style="font-family:Verdana;font-size:12px;">saturable absorption</span><span style="font-family:Verdana;font-size:12px;"> properties</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">were experimentally</span><span style="font-family:Verdana;font-size:12px;"> investigated. The modulation depth, saturation intensity and nonsaturable absorbance</span><span style="font-family:Verdana;font-size:12px;"> of the prepared </span><span style="font-family:Verdana;font-size:12px;">1T-TiSe</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">SA </span><span style="font-family:Verdana;font-size:12px;">were</span><span style="font-family:Verdana;font-size:12px;"> </span><span style="font-family:Verdana;font-size:12px;">1</span><span style="font-family:Verdana;font-size:12px;">5.7</span><span style="font-family:Verdana;font-size:12px;">%,</span><span style="font-family:Verdana;font-size:12px;"> 1.28 M</span><span style="font-family:Verdana;font-size:12px;">W/cm</span><sup><span style="font-family:Verdana;font-size:12px;vertical-align:super;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> and 8.</span><span style="font-family:Verdana;font-size:12px;">2</span><span style="font-family:Verdana;font-size:12px;">%, </span><span style="font-family:Verdana;font-size:12px;">respectively</span><span style="font-family:Verdana;font-size:12px;">. Taking advantage of the saturable absorption properties of </span><span style="font-family:Verdana;font-size:12px;">T</span><span style="font-family:Verdana;font-size:12px;">i</span><span style="font-family:Verdana;font-size:12px;">Se</span><sub><span style="font-family:Verdana;font-size:12px;">2</span></sub><span style="font-family:Verdana;font-size:12px;">-based SA, a passively Q-switched erbium-doped fiber (EDF) laser was</span><span style="font-family:Verdana;font-size:12px;"> systematically demonstrated</span><span style="font-family:Verdana;font-size:12px;">. The pulse repetition rates varied from 24.50 kHz up to 73.79 kHz with the increasing pump power. The obtained shortest pulse width was 1.31 </span><span style="font-family:Verdana;font-size:12px;">μ</span><span style="font-family:Verdana;font-size:12px;">s with pulse energy of 79.28 nJ. The </span><span style="font-family:Verdana;font-size:12px;">system presented merits of low-cost SA preparation, system compactness,</span><span style="font-family:Verdana;font-size:12px;"> superb stability and high competition.</span>