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基于SLICE模型的东台“三医”协同发展和治理实践分析
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作者 宋大平 刘志 甘戈 《中国医院管理》 北大核心 2024年第10期20-22,共3页
医疗、医保、医药协同发展和治理是实现卫生健康事业高质量发展和深化医药卫生体制改革的关键。剖析总结了江苏省东台市医疗、医保、医药协同发展和治理改革在战略设计(导航仪)、组织领导(引擎机)、资源统合(燃料箱)、协同工具(润滑剂)... 医疗、医保、医药协同发展和治理是实现卫生健康事业高质量发展和深化医药卫生体制改革的关键。剖析总结了江苏省东台市医疗、医保、医药协同发展和治理改革在战略设计(导航仪)、组织领导(引擎机)、资源统合(燃料箱)、协同工具(润滑剂)和评估反馈(晴雨表)全闭环方面的经验举措,提炼为“三医”协同发展和治理的SLICE模型,并提出在坚持以改革创新激发“三医”协同发展和治理活力的基础上,充分发挥各级党委、政府的主导作用,建立“三医”协同发展和治理跨部门议事协调机制,吸纳多元主体参与协同治理并强化协同治理措施的系统性,以确保“三医”协同发展和治理改革行稳致远。 展开更多
关键词 “三医”协同发展和治理 slice模型 医药卫生体制改革
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A Retrodirective Array Enabled by CMOS Chips for Two-Way Wireless Communication with Automatic Beam Tracking
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作者 Jiacheng Guo Yizhu Shen +2 位作者 Guoqing Dong Zhuang Han Sanming Hu 《Engineering》 SCIE EI CAS CSCD 2024年第6期196-207,共12页
This article proposes and demonstrates a retrodirective array(RDA)for two-way wireless communication with automatic beam tracking.The proposed RDA is enabled by specifically designed chips made using a domestic comple... This article proposes and demonstrates a retrodirective array(RDA)for two-way wireless communication with automatic beam tracking.The proposed RDA is enabled by specifically designed chips made using a domestic complementary metal-oxide semiconductor(CMOS)process.The highly integrated CMOS chip includes a receiving(Rx)chain,a transmitting(Tx)chain,and a unique tracking phaselocked loop(PLL)for the crucial conjugated phase recovery in the RDA.This article also proposes a method to reduce the beam pointing error(BPE)in a conventional RDA.To validate the above ideas simply yet without loss of generality,a 2.4 GHz RDA is demonstrated through two-way communication links between the Rx and Tx chains,and an on-chip quadrature coupler is designed to achieve a nonretrodirective signal suppression of 23 dBc.The experimental results demonstrate that the proposed RDA,which incorporates domestically manufactured low-cost 0.18 lm CMOS chips,is capable of automatically tracking beams covering±40with a reduced BPE.Each CMOS chip in the RDA has a compact size of 4.62 mm^(2) and a low power consumption of 0.15 W.To the best of the authors’knowledge,this is the first research to demonstrate an RDA with a fully customized CMOS chip for wireless communication with automatic beam tracking。 展开更多
关键词 Automatic beam tracking CMOS Retrodirective array two-way communication
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Reference-frame-independent quantum key distribution with two-way classical communication
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作者 Chun Zhou Hai-Tao Wang +9 位作者 Yi-Fei Lu Xiao-Lei Jiang Yan-Mei Zhao Yu Zhou Yang Wang Jia-Ji Li Yan-Yang Zhou Xiang Wang Hong-Wei Li Wan-Su Bao 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第10期146-152,共7页
The data post-processing scheme based on two-way classical communication(TWCC)can improve the tolerable bit error rate and extend the maximal transmission distance when used in a quantum key distribution(QKD)system.In... The data post-processing scheme based on two-way classical communication(TWCC)can improve the tolerable bit error rate and extend the maximal transmission distance when used in a quantum key distribution(QKD)system.In this study,we apply the TWCC method to improve the performance of reference-frame-independent quantum key distribution(RFI-QKD),and analyze the influence of the TWCC method on the performance of decoy-state RFI-QKD in both asymptotic and non-asymptotic cases.Our numerical simulation results show that the TWCC method is able to extend the maximal transmission distance from 175 km to 198 km and improve the tolerable bit error rate from 10.48%to 16.75%.At the same time,the performance of RFI-QKD in terms of the secret key rate and maximum transmission distance are still greatly improved when statistical fluctuations are considered.We conclude that RFI-QKD with the TWCC method is of practical interest. 展开更多
关键词 quantum key distribution reference-frame-independent two-way classical communication
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Resource Allocation for Cognitive Network Slicing in PD-SCMA System Based on Two-Way Deep Reinforcement Learning
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作者 Zhang Zhenyu Zhang Yong +1 位作者 Yuan Siyu Cheng Zhenjie 《China Communications》 SCIE CSCD 2024年第6期53-68,共16页
In this paper,we propose the Two-way Deep Reinforcement Learning(DRL)-Based resource allocation algorithm,which solves the problem of resource allocation in the cognitive downlink network based on the underlay mode.Se... In this paper,we propose the Two-way Deep Reinforcement Learning(DRL)-Based resource allocation algorithm,which solves the problem of resource allocation in the cognitive downlink network based on the underlay mode.Secondary users(SUs)in the cognitive network are multiplexed by a new Power Domain Sparse Code Multiple Access(PD-SCMA)scheme,and the physical resources of the cognitive base station are virtualized into two types of slices:enhanced mobile broadband(eMBB)slice and ultrareliable low latency communication(URLLC)slice.We design the Double Deep Q Network(DDQN)network output the optimal codebook assignment scheme and simultaneously use the Deep Deterministic Policy Gradient(DDPG)network output the optimal power allocation scheme.The objective is to jointly optimize the spectral efficiency of the system and the Quality of Service(QoS)of SUs.Simulation results show that the proposed algorithm outperforms the CNDDQN algorithm and modified JEERA algorithm in terms of spectral efficiency and QoS satisfaction.Additionally,compared with the Power Domain Non-orthogonal Multiple Access(PD-NOMA)slices and the Sparse Code Multiple Access(SCMA)slices,the PD-SCMA slices can dramatically enhance spectral efficiency and increase the number of accessible users. 展开更多
关键词 cognitive radio deep reinforcement learning network slicing power-domain non-orthogonal multiple access resource allocation
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Beamforming Design for IRS-and-UAV-Aided Two-Way Amplify-and-Forward Relay Networks in Maritime IoT
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作者 Wang Xuehui Shu Feng +6 位作者 Wu Yuanyuan Shi Weiping Yan Shihao Zhao Yifan Cheng Qiankun Sun Zhongwen Wang Jiangzhou 《China Communications》 SCIE CSCD 2024年第8期45-61,共17页
In this paper,an intelligent reflecting surface(IRS)-and-unmanned aerial vehicle(UAV)-assisted two-way amplify-and-forward(AF)relay network in maritime Internet of Things(IoT)is proposed,where ship1(S1)and ship2(S2)ca... In this paper,an intelligent reflecting surface(IRS)-and-unmanned aerial vehicle(UAV)-assisted two-way amplify-and-forward(AF)relay network in maritime Internet of Things(IoT)is proposed,where ship1(S1)and ship2(S2)can be viewed as data collecting centers.To enhance the message exchange rate between S1 and S2,a problem of maximizing minimum rate is cast,where the variables,namely AF relay beamforming matrix and IRS phase shifts of two time slots,need to be optimized.To achieve a maximum rate,a low-complexity alternately iterative(AI)scheme based on zero forcing and successive convex approximation(LC-ZF-SCA)algorithm is presented.To obtain a significant rate enhancement,a high-performance AI method based on one step,semidefinite programming and penalty SCA(ONSSDP-PSCA)is proposed.Simulation results show that by the proposed LC-ZF-SCA and ONS-SDP-PSCA methods,the rate of the IRS-and-UAV-assisted AF relay network surpass those of with random phase and only AF relay networks.Moreover,ONS-SDP-PSCA perform better than LC-ZF-SCA in aspect of rate. 展开更多
关键词 BEAMFORMING maritime Internet of Things phase shift rate performance two-way amplify-and-forward relay unmanned aerial vehicle
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Security-Reliability Analysis and Optimization for Cognitive Two-Way Relay Network with Energy Harvesting
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作者 Luo Yi Zhou Lihua +3 位作者 Dong Jian Sun Yang Xu Jiahui Xi Kaixin 《China Communications》 SCIE CSCD 2024年第11期163-179,共17页
This paper investigates the security and reliability of information transmission within an underlay wiretap energy harvesting cognitive two-way relay network.In the network,energy-constrained secondary network(SN)node... This paper investigates the security and reliability of information transmission within an underlay wiretap energy harvesting cognitive two-way relay network.In the network,energy-constrained secondary network(SN)nodes harvest energy from radio frequency signals of a multi-antenna power beacon.Two SN sources exchange their messages via a SN decode-and-forward relay in the presence of a multiantenna eavesdropper by using a four-phase time division broadcast protocol,and the hardware impairments of SN nodes and eavesdropper are modeled.To alleviate eavesdropping attacks,the artificial noise is applied by SN nodes.The physical layer security performance of SN is analyzed and evaluated by the exact closed-form expressions of outage probability(OP),intercept probability(IP),and OP+IP over quasistatic Rayleigh fading channel.Additionally,due to the complexity of OP+IP expression,a self-adaptive chaotic quantum particle swarm optimization-based resource allocation algorithm is proposed to jointly optimize energy harvesting ratio and power allocation factor,which can achieve security-reliability tradeoff for SN.Extensive simulations demonstrate the correctness of theoretical analysis and the effectiveness of the proposed optimization algorithm. 展开更多
关键词 artificial noise energy harvesting cognitive two-way relay network hardware impairments physical layer security security-reliability tradeoff self-adaptive quantum particle swarm optimization
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基于Slice的H.264并行视频编码算法 被引量:11
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作者 宁华 梅铮 李锦涛 《计算机工程》 EI CAS CSCD 北大核心 2005年第4期181-182,211,共3页
从H.264视频编码标准的特点出发,提出了基于Slice级别的H.264视频编码并行算法,该算法不仅能够保证节点间的负载平衡,减少各节点间数据的依赖关系,还充分利用了已有的计算能力。最后给出了在曙光3000上的实验结果。
关键词 H.264 视频编码 并行 slice
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Two-way中继系统中的双向中继选择及功率分配策略 被引量:7
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作者 刘通 陈前斌 +1 位作者 唐伦 张力生 《计算机应用研究》 CSCD 北大核心 2010年第7期2697-2699,2703,共4页
通过中继选择和功率分配,可以达到提高two-way中继系统总速率的目的。综合考虑中继节点处的接收信噪比和中继节点到目的节点间的信道增益,提出了two-way AF中继系统中的双向中继选择策略(BRS);同时,在总功率受限的条件下,建立了two-way... 通过中继选择和功率分配,可以达到提高two-way中继系统总速率的目的。综合考虑中继节点处的接收信噪比和中继节点到目的节点间的信道增益,提出了two-way AF中继系统中的双向中继选择策略(BRS);同时,在总功率受限的条件下,建立了two-way AF中继系统中的优化功率分配模型,通过对模型进行数学分析求解,提出了一种自适应的最优功率分配策略(OPA)。仿真结果证明两种策略均能提高系统总速率。 展开更多
关键词 two-way中继 AF 中继选择 功率分配
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Two-way中继系统中基于最小化中断概率的功率分配策略 被引量:3
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作者 刘通 陈前斌 +1 位作者 唐伦 张力生 《计算机应用研究》 CSCD 北大核心 2011年第3期1108-1110,共3页
为了降低Two-way中继系统中断概率,提出了一种Two-way中继系统中基于最小化中断概率的功率分配策略。首先推导了Two-way中继系统中断概率的闭合表达式,然后在总功率受限的条件下,提出了一种最小化中断概率的最优功率分配策略(OPA),通过... 为了降低Two-way中继系统中断概率,提出了一种Two-way中继系统中基于最小化中断概率的功率分配策略。首先推导了Two-way中继系统中断概率的闭合表达式,然后在总功率受限的条件下,提出了一种最小化中断概率的最优功率分配策略(OPA),通过拉格朗日乘数法对该优化模型进行了求解。仿真结果证明了该策略能够有效降低系统的中断概率,提高系统性能。 展开更多
关键词 two-way中继 中断概率 功率分配
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Effect of slice scope on data slice-based class cohesion metrics 被引量:3
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作者 周毓明 徐宝文 《Journal of Southeast University(English Edition)》 EI CAS 2008年第2期174-177,共4页
This paper suggests that a single class rather than methods should be used as the slice scope to compute class cohesion. First, for a given attribute, the statements in all methods that last define the attribute are c... This paper suggests that a single class rather than methods should be used as the slice scope to compute class cohesion. First, for a given attribute, the statements in all methods that last define the attribute are computed. Then, the forward and backward data slices for this attribute are generated by using the class as the slice scope and are combined to compute the corresponding class data slice. Finally, the class cohesion is computed based on all class data slices for the attributes. Compared to traditional cohesion metrics that use methods as the slice scope, the proposed metrics that use a single class as slice scope take into account the possible interactions between the methods. The experimental results show that class cohesion can be more accurately measured when using the class as the slice scope. 展开更多
关键词 COHESION class data slice metrics OBJECT-ORIENTED
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AVS编码器Slice并行处理算法研究与实现 被引量:2
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作者 许昌满 李国平 王国中 《中国图象图形学报》 CSCD 北大核心 2009年第6期1108-1113,共6页
介绍了一种基于多slice的并行AVS实时编码器的算法研究与实现,基于slice的并行编码的优点是处理速度快、延迟小和数据处理简单,缺点是条纹效应。介绍了一种对基于slice的并行编码带来的条纹效应缺点进行改进的方法。实验结果表明,实现标... 介绍了一种基于多slice的并行AVS实时编码器的算法研究与实现,基于slice的并行编码的优点是处理速度快、延迟小和数据处理简单,缺点是条纹效应。介绍了一种对基于slice的并行编码带来的条纹效应缺点进行改进的方法。实验结果表明,实现标清AVS实时编码器是可行的。 展开更多
关键词 AVS实时编码器 条纹效应 并行处理 条带
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A Slice Analysis-Based Bayesian Inference Dynamic Power Model for CMOS Combinational Circuits
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作者 陈杰 佟冬 +2 位作者 李险峰 谢劲松 程旭 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第3期502-509,共8页
To improve the accuracy and speed in cycle-accurate power estimation, this paper uses multiple dimensional coefficients to build a Bayesian inference dynamic power model. By analyzing the power distribution and intern... To improve the accuracy and speed in cycle-accurate power estimation, this paper uses multiple dimensional coefficients to build a Bayesian inference dynamic power model. By analyzing the power distribution and internal node state, we find the deficiency of only using port information. Then, we define the gate level number computing method and the concept of slice, and propose using slice analysis to distill switching density as coefficients in a special circuit stage and participate in Bayesian inference with port information. Experiments show that this method can reduce the power-per-cycle estimation error by 21.9% and the root mean square error by 25.0% compared with the original model, and maintain a 700 + speedup compared with the existing gate-level power analysis technique. 展开更多
关键词 slice analysis Bayesian inference power model CMOS combinational circuit
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油显示岩心样品Slice实验研究及其启示 被引量:3
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作者 罗情勇 钟宁宁 李可文 《石油实验地质》 CAS CSCD 北大核心 2015年第2期252-258,共7页
钻井、采样、储存和实验过程中对岩石样品所产生的污染,会影响生物标志物信息的真实性,尤其对于前寒武纪的样品而言,甚至有可能会导致地球早期生命起源和演化的错误解释。通过对中元古界洪水庄组含油显示样品的"剥洋葱式"切片... 钻井、采样、储存和实验过程中对岩石样品所产生的污染,会影响生物标志物信息的真实性,尤其对于前寒武纪的样品而言,甚至有可能会导致地球早期生命起源和演化的错误解释。通过对中元古界洪水庄组含油显示样品的"剥洋葱式"切片(Slice)实验,分析了污染对分子生物标志物的影响。结果表明:饱和烃生物标志物在不同"洋葱片"样品之间差异较大,而芳烃生物标志物的差异较小;除个别参数外,大部分生物标志物参数在内外切片样品之间均存在较大差异。由于在内切片中没有检测到甾烷,因此,中元古界洪水庄组中甾烷的存在与否有待进一步验证。切除样品外皮后进行有机地球化学实验分析能更好的避免污染。 展开更多
关键词 污染 切片实验 油显示样品 生物标志物 洪水庄组 华北北部
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3D-slicer软件辅助神经内镜手术治疗高血压脑出血的临床观察 被引量:1
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作者 蓝欢 马兴才 +4 位作者 赵冠焱 谢昌纪 李光 韦成聪 周志宇 《右江医学》 2020年第10期759-763,共5页
目的观察3D-slicer软件定位在高血压脑出血神经内镜手术中的辅助价值。方法回顾性分析2017年1月至2019年6月神经外科收治的80例高血压脑出血手术患者,根据手术定位方式分组,40例采用3D-slicer软件辅助定位的高血压脑出血神经内镜手术患... 目的观察3D-slicer软件定位在高血压脑出血神经内镜手术中的辅助价值。方法回顾性分析2017年1月至2019年6月神经外科收治的80例高血压脑出血手术患者,根据手术定位方式分组,40例采用3D-slicer软件辅助定位的高血压脑出血神经内镜手术患者作为A组,40例采用常规弦距体表定位的高血压脑出血神经内镜手术患者作为B组,对比观察两组患者的手术时间、术中出血量、平均血肿清除率、住院天数,术前、术后1周GCS评分,术后6个月随访术后神经功能评分(GOS)分级。结果 A组患者的手术时间短于B组,血肿清除率高于B组,术中出血量少于B组,住院时间短于B组(P<0.001)。两组患者的术后1周GCS评分较术前均显著升高(P<0.01),但A组术后1周GCS评分高于B组(P<0.01)。术后6个月GOS分级,A组患者优于B组(P<0.01)。结论使用3D-slice软件辅助神经内镜高血压脑出血手术定位,是一种简单安全、行之有效的治疗方法,可提高患者的临床预后,值得在基层医院推广应用。 展开更多
关键词 高血压脑出血 3D-slicer软件 神经内镜
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Influence of Different Drying Temperatures on Quality of Balsam Pear Slices
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作者 谷俊华 黄斐 《Agricultural Science & Technology》 CAS 2017年第8期1513-1516,1535,共5页
[Objective] The aim was to investigate the effects of different drying temperatures on the physiochemical properties and antioxidant activity of balsam pear slices. [Method] Balsam pear slices were dried at different ... [Objective] The aim was to investigate the effects of different drying temperatures on the physiochemical properties and antioxidant activity of balsam pear slices. [Method] Balsam pear slices were dried at different hot air temperatures, 40, 50, 60, 70 and 80 ℃. [Result] The polyphenols content was highest (2.83 mg/g) in the balsam pear slices dried at 50 ℃, and the flavonoids content was highest (2.584 mg/g) in those dried at 60 ℃. Different drying temperatures had a great impact on the antioxidant capacity of polyphenols in balsam pear. The balsam pear slices dried at 50 ℃ showed the strongest capacity for scavenging DPPH free radicals with IC50 of 0.015 mg/ml, and those dried at 80 ℃ showed the strongest capacity for removing ABTS free radicals with IC50 of 0.0689 mg/ml. [Conclusion] The hot air temperature of 50 ℃ had the least impact on the quality of balsam pear slices. 展开更多
关键词 Balsam pear slice Hot air drying Physiochemical properties Antioxidant activity
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实交错代数上slice正则函数的逼近定理
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作者 陈英伟 陈灿虎 张宝兴 《河北师范大学学报(自然科学版)》 CAS 2022年第1期1-10,共10页
研究了实交错代数上slice正则函数的Runge定理和Carelman型逼近定理.作为特例,在四元数和八元数情形下得出相应的结论.
关键词 slice正则函数 Runge定理 Carleman定理 实交错代数
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Comparison of the Effects of H_2O_2 and Salicylic Acid on Alternative Respiratory Pathway in Aged Potato Tuber Slices
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作者 梁五生 梁厚果 《Acta Botanica Sinica》 CSCD 2002年第3期287-291,共5页
The influences of exogenous H 2O 2 and salicylic acid (SA) treatments on the alternative respiratory pathway (ARP) in aged potato (Solanum tuberosum L.) tuber slices were compared. The results showed that both H 2O... The influences of exogenous H 2O 2 and salicylic acid (SA) treatments on the alternative respiratory pathway (ARP) in aged potato (Solanum tuberosum L.) tuber slices were compared. The results showed that both H 2O 2(5.0 mmol/L) and SA (0.1 mmol/L) treatments had a significant inducing effect on ARP capacity (V alt ) and its ratio to total respiration (V alt /V t) in potato slices aged for 24 h. With a monoclonal antibody against the alternative oxidase (AOX), Western blotting results showed that both H 2O 2 and SA treatments increased the AOX expression levels in aged potato tuber slices. However, the results of oxygen isotope discrimination experiments showed that H 2O 2 had no influence on the in vivo ARP activity (ρV alt ) and its contribution to V t(expressed as ρV alt /V t) in potato slices aged for 24 h, but SA had a significant influence on the ρV alt and ρV alt /V t values of the aged potato tuber slices. These results indicate that there are differences between the effects of H 2O 2 and SA on ARP in plant tissues. Both of them possess the ability to induce ARP capacity through inducing AOX expression. However, SA can simultaneously stimulate the operation of ARP, but H 2O 2 can not. 展开更多
关键词 alternative respiratory pathway H 2O 2 salicylic acid aged potato tuber slices
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Ada软件SLICE分析器(ASA)
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作者 钱红兵 《计算机应用研究》 CSCD 1996年第3期22-24,共3页
对程序进行分析和测试是提高软件可靠性的有效途径。本文介绍的Ada软件SLICE分析器是一种对被测软件进行静态数据流分析的工具,它能缩小用户分析与检查被测程序的范围,帮助用户及时找到所关心的程序段和语句,为保证Ada软... 对程序进行分析和测试是提高软件可靠性的有效途径。本文介绍的Ada软件SLICE分析器是一种对被测软件进行静态数据流分析的工具,它能缩小用户分析与检查被测程序的范围,帮助用户及时找到所关心的程序段和语句,为保证Ada软件系统的质量、提高开发与维护大型复杂软件系统的效率提供支持。 展开更多
关键词 ADA语言 ASA slice 软件 可靠性 程序分析
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多切片模型MSlice格式研究
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作者 王福德 阳佳 《计算机辅助设计与图形学学报》 EI CSCD 北大核心 2003年第8期1044-1048,共5页
在分析了现有其他接口格式如IGES ,STEP和CLI等的利弊之后 ,提出一种新颖的面向多切片模型的数据格式MSlice文件 ,用自行开发的AutoCAD 2 0 0 0下直接切片动态库验证了这一模型 。
关键词 多切片模型 Mslice格式 快速原型制造系统 CAD 计算机辅助设计
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Lipopolysaccharide preconditioning induces protection against lipopolysac-charide -induced neurotoxicity in organotypic midbrain slice culture 被引量:3
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作者 丁晔 李良 《Neuroscience Bulletin》 SCIE CAS CSCD 2008年第4期209-218,共10页
Objective To identify the protective effect of lipopolysaccharide (LPS) preconditioning against LPS-induced inflammatory damage in dopaminergic neurons of midbrain slice culture and the possible mechanisms. Methods ... Objective To identify the protective effect of lipopolysaccharide (LPS) preconditioning against LPS-induced inflammatory damage in dopaminergic neurons of midbrain slice culture and the possible mechanisms. Methods After cultured in vitro for 14 d, the rat organotypic midbrain slices were pretreated with different concentrations (0, 1, 3, 6 or 10 ng/mL) of LPS for 24 h followed by treatment with 100 ng/mL LPS for 72 h. The whole slice viability was detelmined by measurement of the activity of lactic acid dehydrogenase (LDH). Tyrosine hydroxylase-immunoreactive (TH-IR) neurons and CD 1 1 b/c equivalent-immunoreactive (OX-42-IR) microglia in the slices were observed by immunohistochemical method, and tumor necrosis factor-α (TNF-α levels in the culture media were detected by enzymelinked immunosorbent assays (ELISA). Results In the slices treated with 100 ng/mL LPS for 72 h, the number of TH-IR neurons reduced from 191± 12 in the control slices to 46±4, and the LDH activity elevated obviously (P 〈 0.01), along with remarkably increased number of OX-42-IR cells and production of TNF-α (P 〈 0.01). Preconditioning with 3 or 6 ng/mL LPS attenuated neuron loss (the number of TH-IR neurons increased to 126± 12 and 180± 13, respectively) and markedly reduced LDH levels (P 〈 0.05), accompanied by significant decreases of OX-42-IR microglia activation and TNF-α production (P 〈 0.05). Conclusion Low-dose LPS preconditioning could protect dopaminergic neurons against inflammatory damage in rat midbrain slice culture, and inhibition of microglial activation and reduction of the proinflammatory factor TNF-α production may contribute to this protective effect. Further understanding the underlying mechanism of LPS preconditioning may open a new window for treatment of Parkinson's disease. 展开更多
关键词 LIPOPOLYSACCHARIDE PRECONDITIONING neuroprotection organotypic midbrain slice culture dopaminergic neuronsinflammation MICROGLIA tumor necrosis factor-α
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