Controllable and high-throughput preparation of microdroplet using an ultra-high speed rotating packed bed

Microdroplets and their dispersion,with a large specific surface area and a short diffusion distance,have been applied in various unit operations and reaction processes.However,it is still a challenge to control the size and size distribution of microdroplets,especially for high-throughput generation.In this work,a novel ultra-high speed rotating packed bed(UHS-RPB)was invented,in which rotating foam packing with a speed of 4000-12000 r·min^(-1) provides microfluidic channels to disperse liquid into microdroplets with high throughput.Then generated microdroplets can be directly dispersed into a continuous falling film for obtaining a mixture of microdroplet dispersion.In this UHS-RPB,the effects of rotational speed,liquid initial velocity,liquid viscosity,liquid surface tension and packing pore size on the average size(d_(32))and size distribution of microdroplets were systematically investigated.Results showed that the UHS-RPB could produce microdroplets with a d_(32) of 25-63μm at a liquid flow rate of 1025 L·h^(-1),and the size distribution of the microdroplets accords well with Rosin-Rammler distribution model.In addi-tion,a correlation was established for the prediction of d_(32),and the predicted d_(32) was in good agreement with the experimental data with a deviation within±15%.These results demonstrated that UHS-RPB could be a promising candidate for controllable preparation of uniform microdroplets.

Dynamic interactive bitwise meta-holography with ultra-high computational and display frame rates

Interactive holography offers unmatched levels of immersion and user engagement in the field of future display.Despite of the substantial progress has been made in dynamic meta-holography,the realization of real-time,highly smooth interactive holography remains a significant challenge due to the computational and display frame rate limitations.In this study,we introduced a dynamic interactive bitwise meta-holography with ultra-high computational and display frame rates.To our knowledge,this is the first reported practical dynamic interactive metasurface holographic system.We spa-tially divided the metasurface device into multiple distinct channels,each projecting a reconstructed sub-pattern.The switching states of these channels were mapped to bitwise operations on a set of bit values,which avoids complex holo-gram computations,enabling an ultra-high computational frame rate.Our approach achieves a computational frame rate of 800 kHz and a display frame rate of 23 kHz on a low-power Raspberry Pi computational platform.According to this methodology,we demonstrated an interactive dynamic holographic Tetris game system that allows interactive gameplay,color display,and on-the-fly hologram creation.Our technology presents an inspiration for advanced dynamic meta-holography,which is promising for a broad range of applications including advanced human-computer interaction,real-time 3D visualization,and next-generation virtual and augmented reality systems.

Mechanical Behavior Based on Aggregates Microstructure of Ultra-high Performance Concrete

We developed ultra-high performance concrete(UHPC)incorporating mullite sand and brown corundum sand(BCS),and the quartz sand UHPC was utilized to prepare for comparison.The properties of compressive strength,elastic modulus,ultrasonic pulse velocity,flexural strength,and toughness were investigated.Scanning electron microscopy and nanoindentation were also conducted to reveal the underlying mechanisms affecting macroscopic performance.Due to the superior interface bonding properties between mullite sand and matrix,the compressive strength and flexural toughness of UHPC have been significantly improved.Mullite sand and BCS aggregates have higher stiffness than quartz sand,contributing to the excellent elastic modulus exhibited by UHPC.The stiffness and volume of aggregates have a more significant impact on the elastic modulus of UHPC than interface performance,and the latter contributes more to the strength of UHPC.This study will provide a reference for developing UHPC with superior elastic modulus for structural engineering.

Channel assignment and power allocation for throughput improvement with PPO in B5G heterogeneous edge networks

In Beyond the Fifth Generation(B5G)heterogeneous edge networks,numerous users are multiplexed on a channel or served on the same frequency resource block,in which case the transmitter applies coding and the receiver uses interference cancellation.Unfortunately,uncoordinated radio resource allocation can reduce system throughput and lead to user inequity,for this reason,in this paper,channel allocation and power allocation problems are formulated to maximize the system sum rate and minimum user achievable rate.Since the construction model is non-convex and the response variables are high-dimensional,a distributed Deep Reinforcement Learning(DRL)framework called distributed Proximal Policy Optimization(PPO)is proposed to allocate or assign resources.Specifically,several simulated agents are trained in a heterogeneous environment to find robust behaviors that perform well in channel assignment and power allocation.Moreover,agents in the collection stage slow down,which hinders the learning of other agents.Therefore,a preemption strategy is further proposed in this paper to optimize the distributed PPO,form DP-PPO and successfully mitigate the straggler problem.The experimental results show that our mechanism named DP-PPO improves the performance over other DRL methods.

Improving throughput in SWIPT-based wireless multirelay networks with relay selection and rateless codes

This paper studies a dual-hop Simultaneous Wireless Information and Power Transfer(SWIPT)-based multi-relay network with a direct link.To achieve high throughput in the network,a novel protocol is first developed,in which the network can switch between a direct transmission mode and a Single-Relay-Selection-based Cooperative Transmission(SRS-CT)mode that employs dynamic decode-and-forward relaying accomplished with Rateless Codes(RCs).Then,under this protocol,an optimization problem is formulated to jointly optimize the network operation mode and the resource allocation in the SRS-CT mode.The formulated problem is difficult to solve because not only does the noncausal Channel State Information(CSI)cause the problem to be stochastic,but also the energy state evolution at each relay is complicated by network operation mode decision and resource allocation.Assuming that noncausal CSI is available,the stochastic optimization issue is first to be addressed by solving an involved deterministic optimization problem via dynamic programming,where the complicated energy state evolution issue is addressed by a layered optimization method.Then,based on a finite-state Markov channel model and assuming that CSI statistical properties are known,the stochastic optimization problem is solved by extending the result derived for the noncausal CSI case to the causal CSI case.Finally,a myopic strategy is proposed to achieve a tradeoff between complexity and performance without the knowledge of CSI statistical properties.The simulation results verify that our proposed SRS-and-RC-based design can achieve a maximum of approximately 40%throughput gain over a simple SRS-and-RC-based baseline scheme in SWIPT-based multi-relay networks.

The Influence of Chemical Admixtures on the Fluidity,Viscosity and Rheological Properties of Ultra-High Performance Concrete

To achieve higher strength and better durability,ultra-high performance concrete(UHPC)typically employs a relatively small water-binder ratio.However,this generally leads to an undesired increase in the paste viscosity.In this study,the effects of liquid and powder polycarboxylate superplasticizers(PCE)on UHPC are compared and critically discussed.Moreover,the following influential factors are considered:air-entraining agents(AE),slump retaining agents(SA),and defoaming agents(DF)and the resulting flow characteristics,mechanical properties,and hydration properties are evaluated assuming UHPC containing 8‰powder PCE(PCE-based UHPC).It is found that the spread diameter of powder PCE is 5%higher than that of liquid PCE.Among the chemical admixtures studied,AEs have the best effect on improving UHPC workability,while DFs have the worst effect.When the addition of AE and SA is 1.25‰and 14.7%of PCE,paste viscosity reduces by 35%and 19%,respectively compared to the paste with only 8‰PCE.A low AE dosage(1.25‰)decreases compressive strength by 4.1%,while SA(8.1%)increases UHPC compressive strength by 9.1%.Both AE and SA significantly delay the UHPC hydration process,reducing the hydration heat release peaks by 76%and 27%,respectively.

Effect of Shrinkage Reducing Agent and Steel Fiber on the Fluidity and Cracking Performance of Ultra-High Performance Concrete

Due to the low water-cement ratio of ultra-high-performance concrete(UHPC),fluidity and shrinkage cracking are key aspects determining the performance and durability of this type of concrete.In this study,the effects of different types of cementitious materials,chemical shrinkage-reducing agents(SRA)and steel fiber(SF)were assessed.Compared with M2-UHPC and M3-UHPC,M1-UHPC was found to have better fluidity and shrinkage cracking performance.Moreover,different SRA incorporation methods,dosage and different SF types and aspect ratios were implemented.The incorporation of SRA and SF led to a decrease in the fluidity of UHPC.SRA internal content of 1%(NSRA-1%),SRA external content of 1%(WSRA-1%),STS-0.22 and STE-0.7 decreased the fluidity of UHPC by 3.3%,8.3%,9.2%and 25%,respectively.However,SRA and SF improved the UHPC shrinkage cracking performance.NSRA-1%and STE-0.7 reduced the shrinkage value of UHPC by 40%and 60%,respectively,and increased the crack resistance by 338%and 175%,respectively.In addition,the addition of SF was observed to make the microstructure of UHPC more compact,and the compressive strength and flexural strength of 28 d were increased by 26.9%and 19.9%,respectively.

Remaining oil distribution characteristics in an oil reservoir with ultra-high water-cut

An accurate mapping and understanding of remaining oil distribution is very important for water control and stabilize oil production of mature oilfields in ultra-high water-cut stage.Currently,the Tuo-21 Fault Block of the Shengtuo Oilfield has entered the stage of ultra-high water cut(97.2%).Poor adaptability of the well pattern,ineffective water injection cycle and low efficiency of engineering measures(such as workover,re-perforation and utilization of high-capacity pumps)are the significant problems in the ultra-high water-cut reservoir.In order to accurately describe the oil and water flow characteristics,relative permeability curves at high water injection multiple(injected pore volume)and a semiquantitative method is applied to perform fine reservoir simulation of the Sand group 3e7 in the Block.An accurate reservoir model is built and history matching is performed.The distribution characteristics of remaining oil in lateral and vertical directions are quantitatively simulated and analyzed.The results show that the numerical simulation considering relative permeability at high injection multiple can reflect truly the remaining oil distribution characteristics after water flooding in an ultrahigh water-cut stage.The distribution of remaining oil saturation can be mapped more accurately and quantitatively by using the‘four-points and five-types’classification method,providing a basis for potential tapping of various remaining oil types of oil reservoirs in late-stage of development with high water-cut.

A universal multifunctional dual cation doping strategy towards stabilized ultra-high nickel cobalt-free lithium layered oxide cathode

Ultra-high nickel cobalt-free lithium layered oxides are promising cathode material for lithium-ion batteries(LIBs)because of their relatively high capacity and low cost.Nevertheless,the high nickel content would induce bulk structure degradation and interfacial environment deterioration,and the absence of Co element reduces the lithium diffusion kinetics,severely limiting the performance liberation of this kind of cathodes.Herein,a multifunctional Ti/Zr dual cation co-doping strategy has been employed to improve the lithium storage performance of LiNi_(0.9)Mn_(0.1)O_(2)(NM91)cathode.On the one hand,the Ti/Zr co-doping weakens the Li^(+)/Ni^(2+)mixing through magnetic interactions due to the inexistence of unpaired electrons for Ti^(4+)and Zr^(4+),increasing the lithium diffusion rate and suppressing the harmful coexistence of H1 and H2 phases.On the other hand,they enhance the lattice oxygen stability because of the strong Ti-O and Zr-O bonds,inhibiting the undesired H3 phase transition and lattice oxygen loss,improving the bulk structure and cathode-electrolyte interface stability.As a result,the Ti/Zr co-doped NM91(NMTZ)exhibits a 91.2%capacity retention rate after 100 cycles,while that of NM91 is only82.9%.Also,the NMTZ displays better rate performance than NM91 with output capacities of 115 and93 mA h g^(-1)at a high current density of 5 C,respectively.Moreover,the designed NMTZ could enable the full battery to deliver an energy density up to 263 W h kg^(-1),making the ultra-high nickel cobaltfree lithium layered oxide cathode closer to practical applications.

Amine-functionalized metal organic framework@graphene oxide as filler in PAEK-containing carboxyl group membrane for ultrafiltration with ultra-high permeability and strong fouling resistance

Achieving high fouling resistance and permeability using membrane separation technology in water treatment processes remains a challenge.In this work,a novel mixed-matrix membrane(MMM)(poly(arylene ether ketone)[PAEK]-containing carboxyl groups[PAEK-COOH]/UiO-66-NH_(2)@graphene oxide[GO])with superb fouling resistance and high permeability was prepared by the nonsolvent-induced phase separation method,by in-situ growth of UiO-66-NH_(2) on the GO layer,and by preparing hydrophilic PAEK-COOH.On the basis of the structure and performance analysis of the MMM,the maximum water flux reached 591.25 L·m^(-2)·h^(-1) for PAEK-COOH/UiO-66-NH_(2)@GO,whereas the retention rate for bovine serum albumin increased from 85.40%to 94.87%.As the loading gradually increased,the hydrophilicity of the MMMs increased,significantly enhancing their fouling resistance.The strongest anti-fouling ability observed was 94.74%,which was 2.02 times greater than that of the pure membrane.At the same time,the MMMs contained internal amide and hydrogen bonds during the preparation process,forming a cross-linked structure,which further enhanced the mechanical strength and chemical stability.In summary,the MMMs with high retention rate,strong permeability,and anti-fouling ability were successfully prepared.

Analysis of throughput and stability for ACK-ALOHA-CDMA channel

A new acknowledgment-type slotted-ALOHA code division multiple access （ACK-ALOHA-CDMA） channel which can be used in the inbound channels of very small aperture terminal（VSAT） networks is proposed in order to simplify the synchronization equipment of networks in the slotted-ALOHA- CDMA systems. By dividing all VSAT stations into M subsystems and sending out periodic inquiry signals from the Hub station to the VSAT station, the channel model is established. By the means of deriving multi-access interference（MAI） and packet detecting probability, steady-state throughput is calculated. By applying diffusion process theory to the analysis of the stability of the ACK-ALOHA-CDMA channel, the drift parameter a（r）, the diffusion parameter b（r） and the steady transition probability density p （r） are investigated. Simulation results indicate that significant performance improvement and high-bandwidth efficiency can be gained and one or two steady equilibrium points can be obtained by using this channel. Consequently, the ACK- ALOHA-CDMA channel is very suitable for cutting down on the expense of satellite VSAT systems and distributed packet radio networks.

Throughput scheduling in cognitive radio networks based on immune optimization

To study the throughput scheduling problem under interference temperature in cognitive radio networks, an immune algorithm-based suboptimal method was proposed based on its NP-hard feature. The problem is modeled as a constrained optimization problem to maximize the total throughput of the secondary users（ SUs）. The mapping between the throughput scheduling problems and the immune algorithm is given. Suitable immune operators are designed such as binary antibody encoding, antibody initialization based on pre-knowledge, a proportional clone to its affinity and an adaptive mutation operator associated with the evolutionary generation. The simulation results showthat the proposed algorithm can obtain about 95% of the optimal throughput and operate with much lower liner computational complexity.

氧化苦参碱对牙周膜干细胞干性标志物表达和成骨分化的作用

背景:人牙周膜干细胞是牙周再生组织工程潜在的功能细胞,然而长期体外培养会导致牙周膜干细胞干性减低并发生复制性衰老,从而影响其治疗效果。目的:探讨氧化苦参碱在体外对牙周膜干细胞干性维持和骨向分化的影响,并寻找潜在的影响机制。方法:采用组织块酶消化法从人牙周膜组织中分离、培养得到牙周膜干细胞,并使用流式细胞仪进行间充质细胞表面标志物鉴定。用0,2.5,5,10μg/mL氧化苦参碱孵育牙周膜干细胞,通过CCK8实验检测氧化苦参碱对牙周膜干细胞增殖活性的影响,筛选后续实验合适的药物质量浓度,采用Western blot检测牙周膜干细胞中干细胞非特异性蛋白SOX2和OCT4的表达,采用qRT-PCR、Western blot检测牙周膜干细胞中成骨相关基因和蛋白表达水平。结果与结论:①CCK8实验结果显示2.5μg/mL氧化苦参碱对牙周膜干细胞增殖活性有显著增强作用,后续实验选用2.5μg/mL氧化苦参碱进行干预;②与空白对照组相比,氧化苦参碱组牙周膜干细胞的干性标志物SOX2蛋白表达水平变化不明显(P>0.05),OCT4蛋白表达明显上调(P<0.05);③与成骨诱导组相比,氧化苦参碱+成骨诱导组牙周膜干细胞成骨相关基因ALP、RUNX2 mRNA表达及成骨相关蛋白ALP蛋白表达明显下调(P<0.05);④氧化苦参碱上调牙周膜干细胞干性标志物表达,抑制牙周膜干细胞骨向分化,高通量测序结果表明可能与WNT2、WNT16、COMP、BMP6有关。

WiFi终端Throughput测试分析及LTE终端Throughput测试研究

针对智能终端的WiFi接收模块的吞吐量进行测试及结果分析得出结论,并对之前设计的测试吞吐量空口测试方法加以验证,为智能终端的WiFi接收模块设计提供数据参考和设计思路,为下一步智能电视性能测试标准提供参考依据和数据支撑,同时对移动终端(LTE终端)应用层吞吐量测试进行了延伸研究,介绍了相关测试概念和方法。

HIGH THROUGHPUT DRILLING OF TITANIUM ALLOYS

The experiments of high throughput drilling of Ti-6Al-4V at 183 m/min cutting speed and 156 mm^3/s material removal rate using a 4 mm diameter WC-Co spiral point drill are conducted. At this material removal rate, it took only 0.57 s to drill a hole in a 6.35 mm thick Ti plate. Supplying the cutting fluid via through-the-drill holes and the balance of cutting speed and feed have proven to be critical for drill life. An inverse heat transfer model is developed to predict the heat flux and the drill temperature distribution in drilling. A three-dimensional finite element modeling of drilling is con-ducted to predict the thrust force and torque. Experimental result demonstrates that, using proper machining process parameters, tool geometry, and fine-grained WC-Co tool material, the high throughput machining of Ti alloy is technically feasible.

High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases

RNA sequencing is the use of hight hroughput next generation sequencing technology to survey, characterize, and quantify the transcriptome of a genome. RNA sequencing has been used to analyze the pathogenesis of several malignancies such melanoma, lung cancer, and colorectal cancer. RNA sequencing can identify differential expression of genes(DEG's), mutated genes, fusion genes, and gene isoforms in disease states. RNA sequencing has been used in the investigation of several colorectal diseases such as colorectal cancer, inflammatory bowel disease(ulcerative colitis and Crohn's disease), and irritable bowel syndrome.

High Throughput Sequencing of circRNAs in Tomato Leaves Responding to Multiple Stresses of Drought and Heat

Our aim is to study the roles of a new emerging group of non-coding RNAs, circRNAs, in tomato(Solanum lycopersicum L.) plants grown at the combination of drought and heat, two of the most usual stress conditions known to frequently happen in field. Tomato seedlings from cultivar‘Jinling Meiyu’ were treated without stresses(control), at water shortage, high temperature and subjected the multiple stresses. In total, 467 circRNAs were identified with 87.82% from exon using high throughput sequencing technology. Among the circRNAs, 70 were from chr1 with the range from 23 to 49 from the other chromosomes. In detail, 156 circRNAs were shared in the four libraries, while 21, 17 and 36 circRNAs were only shown in drought, heat and multiple stresses libraries, respectively. Through a differential expression analysis, four, seven and nine circRNAs were differentially regulated in tomato at drought, heat and multiple stresses as compared with control. These circRNAs played roles on photosynthesis, starch and sucrose metabolism, RNA transport, RNA degradation, spliceosome, ribosome, etc. Our study underlined the potential role of circRNAs involved in the abiotic stress response in tomato, which might pave the way for studying biological roles of circRNAs responding to multiple stresses in plants.

DIRECTIONALLY SOLIDIFIED MICROSTRUCTURE OF AN ULTRA-HIGH TEMPERATURE Nb-Si-Ti-Hf-Cr-Al ALLOY

The directionally solidified samples of an ultra-high temperature Nb-Si-Ti-Hf-Cr-Al alloy have been prepared with the use of an electron beam floating zone melting (EBFZM) furnace, and their microstructural characteristics have been analyzed. All the primary dendrites of Nb solid solution (Nbss), eutectic colonies of Nba, plus (Nb, Ti)3 Si/(Nb, Ti)5 Si3 and chains of (Nb, Ti)3 Si/(Nb, Ti)5 Si3 plates align along the growth direction of the samples. With increasing of the withdrawing rate, the microstructure is refined, and the amounts of Nbss+ (Nb, Ti)3 Si/(Nb, Ti)5 Si3 eutectic colonies and (Nb, Ti)3 Si/(Nb, Ti)5 Si3 plates increase. There appear nodes in the (Nb, Ti)3 Si/(Nb, Ti)5 Si3 plates.

Throughput Analysis of the IEEE 802.11 Distributed Coordination Function Considering Erroneous Channel and Capture Effects

This paper presents a performance study of the distributed coordination function （DCF） of 802.11 networks considering erroneous channel and capture effects under non-saturated traffic conditions employing a basic access method.The aggregate throughput of a practical wireless local area network （WLAN） strongly depends on the channel conditions.In a real radio environment,the received signal power at the access point from a station is subjected to deterministic path loss,shadowing,and fast multipath fading.The binary exponential backoff （BEB） mechanism of IEEE 802.11 DCF severely suffers from more channel idle time under high bit error rate （BER）.To alleviate the low performance of IEEE 802.11 DCF,a new mechanism is introduced,which greatly outperforms the existing methods under a high BER.A multidimensional Markov chain model is used to characterize the behavior of DCF in order to account both non-ideal channel conditions and capture effects.

New Spheroidizing Technique of Ultra-High Carbon Steel With Aluminum Addition

A new spheroidizing process of ultra-high carbon steel （UHCS） containing C 1.55%, Cr 1.45%, and Al 1.5% in mass percent has been proposed. The effect of processing parameters on the microstructure was analyzed. The UHCS produced by this new process has a microstructure with recrystallized ferrite matrix and fine and uniform carbide particles. After this spheroidizing, the UHCS exhibits good mechanical properties at ambient temperature, for example σb= 1 100 MPa, σs =915 MPa, δ=8% and high ratio of σs/σb.