Since carbon dioxide laser is excellent for incision, hemostasis, coagulation, and vaporization of soft tissues, it has been widely applied in clinical treatments as the laser knife. In these days, flexible thin hollo...Since carbon dioxide laser is excellent for incision, hemostasis, coagulation, and vaporization of soft tissues, it has been widely applied in clinical treatments as the laser knife. In these days, flexible thin hollow optical fibers transmitting mid-infrared light have been developed, and the application of carbon dioxide laser to endoscopic therapy has become possible. However, it is expected that the irradiation effect is influenced by the change in the laser power at the tip of the hollow optical fiber due to the change in the transmittance by the bending loss. The purpose of this research is to quantitatively evaluate the change in the output power and therapeutic effect by bending the hollow optical fiber in a gastrointestinal endoscope. The change in the transmittance of the hollow optical fiber due to the insertion of the fiber into the endoscope and bending of the head of the endoscope was measured. Then, the relationship between the irradiated laser power and the incision depth for a porcine stomach was investigated. As the results, the most significant decrease in the transmittance of the hollow optical fiber was caused by the insertion of the fiber into the instrument channel of the endoscope, and bending of the head of the endoscope with the angle of 90° decreased the output laser power and incision depth by 10% and 25%, respectively. Therefore, it was confirmed that the bending loss of the hollow optical fiber due to the bending of the head of the endoscope had no significant influence on the endoscopic therapy using the carbon dioxide laser.展开更多
Ionization and dissociation of linear triatomic molecules, carbon dioxide, are studied in 50-fs 800-nm strong laser fields using time-of-flight mass spectrometer. The yields of double charged ions CO2^2+ and various ...Ionization and dissociation of linear triatomic molecules, carbon dioxide, are studied in 50-fs 800-nm strong laser fields using time-of-flight mass spectrometer. The yields of double charged ions CO2^2+ and various fragment ions(CO^+,O^n+, and C^n+(n = 1, 2)) are measured as a function of ellipticity of laser polarization in the intensity range from 5.0 ×10^13W/cm2 to 6.0 × 10^14W/cm^2. The results demonstrate that non-sequential double ionization, which is induced by laser-driven electron recollision, dominates double ionization of CO2 in the strong IR laser field with intensity lower than2.0 × 10^14W/cm^2. The electron recollision could also have contribution in strong-field multiple ionization and formation of fragments of CO2 molecules. The present study indicates that the intensity and ellipticity dependence of ions yields can be used to probe the complex dynamics of strong-field ionization/dissociation of polyatomic molecules.展开更多
The direct excitation of CO2 using fast (nanosecond) and ultrafast (femtosecond) pulsed lasers was investigated.A gas reaction cell was used to excite CO2 in a 50:50 mixture of CO2 and CH4 using nano-and femtosec...The direct excitation of CO2 using fast (nanosecond) and ultrafast (femtosecond) pulsed lasers was investigated.A gas reaction cell was used to excite CO2 in a 50:50 mixture of CO2 and CH4 using nano-and femtosecond laser systems,to induce a reaction between these two compounds.FT-IR spectra showed that CO was formed using the nanosecond and femtosecond laser systems.It was also found that hydrocarbons,containing C-C bonds were formed.For both the nanosecond and femtosecond laser,it was found that more C-C higher hydrocarbons were formed after 5 h compared to 3 h of irradiation.Irradiation at pressures of 250,350 and 500 kPa with the femtosecond laser system showed the expected increase in the amount of CO formed with an increase in pressure.Results from this study showed that carbon dioxide and methane can be activated successfully using nanosecond laser pulses at 2000 nm and femtosecond laser pulses at 795 or 2000 nm and that these activated species react to form CO and C-C containing products.展开更多
The treatment of atrophoderma vermiculatum is challenging. A 7-year-old girl had a unilateral atrophic skin lesion on her right cheek, which was diagnosed as unilateral atrophoderma vermiculata. She was treated by car...The treatment of atrophoderma vermiculatum is challenging. A 7-year-old girl had a unilateral atrophic skin lesion on her right cheek, which was diagnosed as unilateral atrophoderma vermiculata. She was treated by carbon dioxide and 595 nm pulsed dye laser and carbon dioxide laser. This resulted in prevention of the lesional progression with favorable cosmetic appearance of the skin.展开更多
文摘Since carbon dioxide laser is excellent for incision, hemostasis, coagulation, and vaporization of soft tissues, it has been widely applied in clinical treatments as the laser knife. In these days, flexible thin hollow optical fibers transmitting mid-infrared light have been developed, and the application of carbon dioxide laser to endoscopic therapy has become possible. However, it is expected that the irradiation effect is influenced by the change in the laser power at the tip of the hollow optical fiber due to the change in the transmittance by the bending loss. The purpose of this research is to quantitatively evaluate the change in the output power and therapeutic effect by bending the hollow optical fiber in a gastrointestinal endoscope. The change in the transmittance of the hollow optical fiber due to the insertion of the fiber into the endoscope and bending of the head of the endoscope was measured. Then, the relationship between the irradiated laser power and the incision depth for a porcine stomach was investigated. As the results, the most significant decrease in the transmittance of the hollow optical fiber was caused by the insertion of the fiber into the instrument channel of the endoscope, and bending of the head of the endoscope with the angle of 90° decreased the output laser power and incision depth by 10% and 25%, respectively. Therefore, it was confirmed that the bending loss of the hollow optical fiber due to the bending of the head of the endoscope had no significant influence on the endoscopic therapy using the carbon dioxide laser.
基金supported by the National Basic Research Program of China(Grant No.2013CB922200)the National Natural Science Foundation of China(Grant Nos.11034003 and 11274140)
文摘Ionization and dissociation of linear triatomic molecules, carbon dioxide, are studied in 50-fs 800-nm strong laser fields using time-of-flight mass spectrometer. The yields of double charged ions CO2^2+ and various fragment ions(CO^+,O^n+, and C^n+(n = 1, 2)) are measured as a function of ellipticity of laser polarization in the intensity range from 5.0 ×10^13W/cm2 to 6.0 × 10^14W/cm^2. The results demonstrate that non-sequential double ionization, which is induced by laser-driven electron recollision, dominates double ionization of CO2 in the strong IR laser field with intensity lower than2.0 × 10^14W/cm^2. The electron recollision could also have contribution in strong-field multiple ionization and formation of fragments of CO2 molecules. The present study indicates that the intensity and ellipticity dependence of ions yields can be used to probe the complex dynamics of strong-field ionization/dissociation of polyatomic molecules.
文摘The direct excitation of CO2 using fast (nanosecond) and ultrafast (femtosecond) pulsed lasers was investigated.A gas reaction cell was used to excite CO2 in a 50:50 mixture of CO2 and CH4 using nano-and femtosecond laser systems,to induce a reaction between these two compounds.FT-IR spectra showed that CO was formed using the nanosecond and femtosecond laser systems.It was also found that hydrocarbons,containing C-C bonds were formed.For both the nanosecond and femtosecond laser,it was found that more C-C higher hydrocarbons were formed after 5 h compared to 3 h of irradiation.Irradiation at pressures of 250,350 and 500 kPa with the femtosecond laser system showed the expected increase in the amount of CO formed with an increase in pressure.Results from this study showed that carbon dioxide and methane can be activated successfully using nanosecond laser pulses at 2000 nm and femtosecond laser pulses at 795 or 2000 nm and that these activated species react to form CO and C-C containing products.
文摘The treatment of atrophoderma vermiculatum is challenging. A 7-year-old girl had a unilateral atrophic skin lesion on her right cheek, which was diagnosed as unilateral atrophoderma vermiculata. She was treated by carbon dioxide and 595 nm pulsed dye laser and carbon dioxide laser. This resulted in prevention of the lesional progression with favorable cosmetic appearance of the skin.