Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injectio...Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.展开更多
Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Er...Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed展开更多
目的:探究重组贻贝粘蛋白水凝胶敷料(Recombined mussel adhesive protein hydrogel dressing,Rmaphd)在点阵CO_(2)激光治疗面部痤疮萎缩性瘢痕术后创面修复中的应用效果。方法:选择2022年6月-2023年2月面部痤疮萎缩性瘢痕患者117例,分...目的:探究重组贻贝粘蛋白水凝胶敷料(Recombined mussel adhesive protein hydrogel dressing,Rmaphd)在点阵CO_(2)激光治疗面部痤疮萎缩性瘢痕术后创面修复中的应用效果。方法:选择2022年6月-2023年2月面部痤疮萎缩性瘢痕患者117例,分为Rmaphd组、重组人表皮生长因子(Recombinant human epidermal growth factor,rhEGF)组和对照组,每组39例,三组均给予点阵CO_(2)激光术治疗,术后分别给予Rmaphd、rhEGF及生理盐水处理,比较三组疗效、ECCA评分、症状持续时间以及生活质量评分。结果:Rmaphd组和rhEGF组总有效率分别为92.31%和94.87%,均高于对照组76.92%(P<0.05),术后ECCA评分低于对照组(P<0.05),术后疼痛、红斑、痂皮持续时间短于对照组(P<0.05),Acne-QoL各指标得分优于对照组(P<0.05);上述各临床Rmaphd组与rhEGF组差异无统计学意义(P>0.05)。结论:Rmaphd用于点阵CO_(2)激光治疗面部痤疮萎缩性瘢痕术后创面修复疗效显著,具备在临床上辅助激光治疗术后修复的应用潜力。展开更多
目的:探究点阵CO_(2)激光联合米诺地尔治疗雄激素性脱发(Androgenetic alopecia,AGA)的疗效及安全性分析。方法:选取2020年1月-2021年12月笔者医院收治的114例雄激素性脱发患者,采用单双球法随机分为对照组(n=57)和观察组(n=57),对照组...目的:探究点阵CO_(2)激光联合米诺地尔治疗雄激素性脱发(Androgenetic alopecia,AGA)的疗效及安全性分析。方法:选取2020年1月-2021年12月笔者医院收治的114例雄激素性脱发患者,采用单双球法随机分为对照组(n=57)和观察组(n=57),对照组给予米诺地尔治疗,观察组给予点阵CO_(2)激光与米诺地尔联合治疗。比较治疗6个月后两组患者的临床症状改善情况,对比治疗前和治疗6个月后两组患者治疗效果、毛发镜评价、生活质量[流调中心抑郁表(The center for epidemiological studies depression scale,CES-D)、皮肤病生活质量指数(Dermatology life quality index,DLQI)],记录治疗期间不良反应发生情况。结果:治疗6个月后,观察组临床症状改善评分高于对照组(P<0.05);两组脱发评分、新生发评、毳毛比例、CES-D、DLQI评分均较治疗前降低,观察组低于对照组(P<0.05);两组毛发密度、毛囊密度均较治疗前增大,观察组大于对照组(P<0.05);两组患者不良反应差异无统计学意义(P>0.05)。结论:点阵CO_(2)激光联合米诺地尔可改善AGA患者瘙痒、出油、头屑、毛囊炎等症状及毛发镜指标,改善患者生活质量,且不增加不良反应发生率。展开更多
目的:探究30%超分子水杨酸联合小光斑点阵CO_(2)激光治疗轻中度寻常痤疮的有效性和安全性。方法:选取2022年11月-2023年6月就诊于吉林大学中日联谊医院30例面部轻、中度寻常痤疮患者,以患者面部矢状线为界,按照随机数表将患者的双侧面...目的:探究30%超分子水杨酸联合小光斑点阵CO_(2)激光治疗轻中度寻常痤疮的有效性和安全性。方法:选取2022年11月-2023年6月就诊于吉林大学中日联谊医院30例面部轻、中度寻常痤疮患者,以患者面部矢状线为界,按照随机数表将患者的双侧面部随机分为对照侧和观察侧。对照侧(n=30),给予30%超分子水杨酸治疗(每4周治疗1次);观察侧(n=30),给予小光斑点阵CO_(2)激光治疗后即刻30%超分子水杨酸治疗(每4周治疗1次)。通过拍照、皮肤检测仪、皮损计数和痤疮综合分级系统(The global acne grading system,GAGS)评分等评估治疗的有效性;通过皮损清除率判定临床疗效,同时观察不良反应以评估安全性。治疗结束后12周对患者进行随访,评估复发情况。结果:治疗12周后,患者观察侧的临床疗效优于对照侧(P<0.05);观察侧的皮损清除效果明显优于对照侧(P<0.001);观察侧的GAGS评分改善程度明显优于对照侧(P<0.001)。治疗期间两侧均未出现严重不良反应。结论:30%超分子水杨酸联合小光斑点阵CO_(2)激光疗法对清除轻中度痤疮皮损优于30%超分子水杨酸单一治疗,具有见效快、安全性高、操作简单、患者满意度高等优点,且不增加患者相关不良反应。展开更多
Background: Most data on laser resurfacing have come from studies of people with Fitzpatrick skin types 1 - 3;however, the world’s population is comprised mostly of Fitzpatrick skin types 4 - 6, which are more suscep...Background: Most data on laser resurfacing have come from studies of people with Fitzpatrick skin types 1 - 3;however, the world’s population is comprised mostly of Fitzpatrick skin types 4 - 6, which are more susceptible to post-inflammatory hyperpigmentation (PIH). Objective: For the purpose of expanding the expertise of plastic surgeons treating patients with darker skin types, this study examined the incidence of PIH in Asians who underwent laser resurfacing, including a histologic arm on fractional ablative resurfacing. Methods & Materials: The clinical study included six subjects of Vietnamese origin who underwent single-depth fractionated CO2 laser resurfacing. The histologic study involved a seventh subject. The MiXto SX®laser with a new scanning handpiece was used, along with magnifying loupes to assess ablative depth after each of three laser passes performed. Photographs were taken at various postoperative intervals. Results: All six clinical subjects showed cosmetic improvement in skin texture and tone with no post-inflammatory hyperpigmentation. In the histologic study, H&E stained sections revealed uniform diathermy. Conclusion: It is possible to significantly reduce PIH in darker skinned subjects through use of a new scanning handpiece and a technique using loupes to assess the depth of ablative resurfacing. The histologic study confirms these findings.展开更多
文摘Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.
文摘Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed
文摘目的:探究重组贻贝粘蛋白水凝胶敷料(Recombined mussel adhesive protein hydrogel dressing,Rmaphd)在点阵CO_(2)激光治疗面部痤疮萎缩性瘢痕术后创面修复中的应用效果。方法:选择2022年6月-2023年2月面部痤疮萎缩性瘢痕患者117例,分为Rmaphd组、重组人表皮生长因子(Recombinant human epidermal growth factor,rhEGF)组和对照组,每组39例,三组均给予点阵CO_(2)激光术治疗,术后分别给予Rmaphd、rhEGF及生理盐水处理,比较三组疗效、ECCA评分、症状持续时间以及生活质量评分。结果:Rmaphd组和rhEGF组总有效率分别为92.31%和94.87%,均高于对照组76.92%(P<0.05),术后ECCA评分低于对照组(P<0.05),术后疼痛、红斑、痂皮持续时间短于对照组(P<0.05),Acne-QoL各指标得分优于对照组(P<0.05);上述各临床Rmaphd组与rhEGF组差异无统计学意义(P>0.05)。结论:Rmaphd用于点阵CO_(2)激光治疗面部痤疮萎缩性瘢痕术后创面修复疗效显著,具备在临床上辅助激光治疗术后修复的应用潜力。
文摘目的:探究点阵CO_(2)激光联合米诺地尔治疗雄激素性脱发(Androgenetic alopecia,AGA)的疗效及安全性分析。方法:选取2020年1月-2021年12月笔者医院收治的114例雄激素性脱发患者,采用单双球法随机分为对照组(n=57)和观察组(n=57),对照组给予米诺地尔治疗,观察组给予点阵CO_(2)激光与米诺地尔联合治疗。比较治疗6个月后两组患者的临床症状改善情况,对比治疗前和治疗6个月后两组患者治疗效果、毛发镜评价、生活质量[流调中心抑郁表(The center for epidemiological studies depression scale,CES-D)、皮肤病生活质量指数(Dermatology life quality index,DLQI)],记录治疗期间不良反应发生情况。结果:治疗6个月后,观察组临床症状改善评分高于对照组(P<0.05);两组脱发评分、新生发评、毳毛比例、CES-D、DLQI评分均较治疗前降低,观察组低于对照组(P<0.05);两组毛发密度、毛囊密度均较治疗前增大,观察组大于对照组(P<0.05);两组患者不良反应差异无统计学意义(P>0.05)。结论:点阵CO_(2)激光联合米诺地尔可改善AGA患者瘙痒、出油、头屑、毛囊炎等症状及毛发镜指标,改善患者生活质量,且不增加不良反应发生率。
文摘目的:探究30%超分子水杨酸联合小光斑点阵CO_(2)激光治疗轻中度寻常痤疮的有效性和安全性。方法:选取2022年11月-2023年6月就诊于吉林大学中日联谊医院30例面部轻、中度寻常痤疮患者,以患者面部矢状线为界,按照随机数表将患者的双侧面部随机分为对照侧和观察侧。对照侧(n=30),给予30%超分子水杨酸治疗(每4周治疗1次);观察侧(n=30),给予小光斑点阵CO_(2)激光治疗后即刻30%超分子水杨酸治疗(每4周治疗1次)。通过拍照、皮肤检测仪、皮损计数和痤疮综合分级系统(The global acne grading system,GAGS)评分等评估治疗的有效性;通过皮损清除率判定临床疗效,同时观察不良反应以评估安全性。治疗结束后12周对患者进行随访,评估复发情况。结果:治疗12周后,患者观察侧的临床疗效优于对照侧(P<0.05);观察侧的皮损清除效果明显优于对照侧(P<0.001);观察侧的GAGS评分改善程度明显优于对照侧(P<0.001)。治疗期间两侧均未出现严重不良反应。结论:30%超分子水杨酸联合小光斑点阵CO_(2)激光疗法对清除轻中度痤疮皮损优于30%超分子水杨酸单一治疗,具有见效快、安全性高、操作简单、患者满意度高等优点,且不增加患者相关不良反应。
文摘Background: Most data on laser resurfacing have come from studies of people with Fitzpatrick skin types 1 - 3;however, the world’s population is comprised mostly of Fitzpatrick skin types 4 - 6, which are more susceptible to post-inflammatory hyperpigmentation (PIH). Objective: For the purpose of expanding the expertise of plastic surgeons treating patients with darker skin types, this study examined the incidence of PIH in Asians who underwent laser resurfacing, including a histologic arm on fractional ablative resurfacing. Methods & Materials: The clinical study included six subjects of Vietnamese origin who underwent single-depth fractionated CO2 laser resurfacing. The histologic study involved a seventh subject. The MiXto SX®laser with a new scanning handpiece was used, along with magnifying loupes to assess ablative depth after each of three laser passes performed. Photographs were taken at various postoperative intervals. Results: All six clinical subjects showed cosmetic improvement in skin texture and tone with no post-inflammatory hyperpigmentation. In the histologic study, H&E stained sections revealed uniform diathermy. Conclusion: It is possible to significantly reduce PIH in darker skinned subjects through use of a new scanning handpiece and a technique using loupes to assess the depth of ablative resurfacing. The histologic study confirms these findings.
