Cancer is a major societal public health and economic problem, responsible for one in every six deaths. Radiotherapy is the main technique of treatment for more than half of cancer patients. To achieve a successful ou...Cancer is a major societal public health and economic problem, responsible for one in every six deaths. Radiotherapy is the main technique of treatment for more than half of cancer patients. To achieve a successful outcome, the radiation dose must be delivered accurately and precisely to the tumor, within ± 5% accuracy. Smaller uncertainties are required for better treatment outcome. The objective of the study is to investigate the uncertainty of measurement of external radiotherapy beam using a standard ionization chamber under reference conditions. Clinical farmers type ionization chamber measurement was compared against the National Reference standard, by exposing it in a beam 60Co gamma source. The measurement set up was carried out according to IAEA TRS 498 protocol and uncertainty of measurement evaluated according to GUM TEDDOC-1585. Evaluation and analysis were done for the identified subjects of uncertainty contributors. The expanded uncertainty associated with 56 mGy/nC ND,W was found to be 0.9% corresponding to a confidence level of approximately 95% with a coverage factor of k = 2. The study established the impact of dosimetry uncertainty of measurement in estimating external radiotherapy dose. The investigation established that the largest contributor of uncertainty is the stability of the ionization chamber at 36%, followed by temperature at 22% and positioning of the chamber in the beam at 8%. The effect of pressure, electrometer, resolution, and reproducibility were found to be minimal to the overall uncertainty. The study indicate that there is no flawless measurement, as there are many prospective sources of variation. Measurement results have component of unreliability and should be regarded as best estimates of the true value. .展开更多
A cantilever coordinate measuring machine(CCMM)is proposed according to the in-situ measurement requirement of workpieces with complex structures limited by the finite space of the5-axes computerized numerical control...A cantilever coordinate measuring machine(CCMM)is proposed according to the in-situ measurement requirement of workpieces with complex structures limited by the finite space of the5-axes computerized numerical control(CNC)processing site.Factors affecting uncertainty of measurement(UM)are classified and analyzed on the basis of uncertainty evaluation criteria,and the estimation technique of UM for measuring systems is presented.UM of the CCMM is estimated from the factors such as temperature,error motions as well as the mechanism deformations.Measurement results show that the actual measurement error is smaller than that of measurement requirement.展开更多
On the basis of the fact that physical world possesses hierarchical structure and the concepts of nonstandard mathematics, a new description of turbulence was presented. Fundamental equations of turbulent flows were a...On the basis of the fact that physical world possesses hierarchical structure and the concepts of nonstandard mathematics, a new description of turbulence was presented. Fundamental equations of turbulent flows were also given. It is natural in this nonstandard picture of turbulence that the closure methods are obtained and seem to be precise.展开更多
文摘Cancer is a major societal public health and economic problem, responsible for one in every six deaths. Radiotherapy is the main technique of treatment for more than half of cancer patients. To achieve a successful outcome, the radiation dose must be delivered accurately and precisely to the tumor, within ± 5% accuracy. Smaller uncertainties are required for better treatment outcome. The objective of the study is to investigate the uncertainty of measurement of external radiotherapy beam using a standard ionization chamber under reference conditions. Clinical farmers type ionization chamber measurement was compared against the National Reference standard, by exposing it in a beam 60Co gamma source. The measurement set up was carried out according to IAEA TRS 498 protocol and uncertainty of measurement evaluated according to GUM TEDDOC-1585. Evaluation and analysis were done for the identified subjects of uncertainty contributors. The expanded uncertainty associated with 56 mGy/nC ND,W was found to be 0.9% corresponding to a confidence level of approximately 95% with a coverage factor of k = 2. The study established the impact of dosimetry uncertainty of measurement in estimating external radiotherapy dose. The investigation established that the largest contributor of uncertainty is the stability of the ionization chamber at 36%, followed by temperature at 22% and positioning of the chamber in the beam at 8%. The effect of pressure, electrometer, resolution, and reproducibility were found to be minimal to the overall uncertainty. The study indicate that there is no flawless measurement, as there are many prospective sources of variation. Measurement results have component of unreliability and should be regarded as best estimates of the true value. .
基金National Natural Science Foundation of China(No.51375338)
文摘A cantilever coordinate measuring machine(CCMM)is proposed according to the in-situ measurement requirement of workpieces with complex structures limited by the finite space of the5-axes computerized numerical control(CNC)processing site.Factors affecting uncertainty of measurement(UM)are classified and analyzed on the basis of uncertainty evaluation criteria,and the estimation technique of UM for measuring systems is presented.UM of the CCMM is estimated from the factors such as temperature,error motions as well as the mechanism deformations.Measurement results show that the actual measurement error is smaller than that of measurement requirement.
文摘On the basis of the fact that physical world possesses hierarchical structure and the concepts of nonstandard mathematics, a new description of turbulence was presented. Fundamental equations of turbulent flows were also given. It is natural in this nonstandard picture of turbulence that the closure methods are obtained and seem to be precise.
