Informed consent for digestive endoscopy

Informed consent is necessary in good clinical practice.It is based on the patient’s ability to understand the information about the proposed procedure,the potential consequences and complications,and alternative options.The information is written in understandable language and is fortified by verbal discussion between physician and patient.The aim is to explain the problem,answer all questions and to ensure that the patient understands the problems and is able to make a decision.The theory is clear but what happens in daily practice?

Assessing canopy nitrogen and carbon content in maize by canopy spectral reflectance and uninformative variable elimination

Assessing canopy nitrogen content(CNC) and canopy carbon content(CCC) of maize by hyperspectral remote sensing data permits estimating cropland productivity, protecting farmland ecology, and investigating the nitrogen and carbon cycles in the atmosphere. This study aimed to assess maize CNC and CCC using canopy hyperspectral information and uninformative variable elimination(UVE). Vegetation indices(VIs) and wavelet functions were adopted for estimating CNC and CCC under varying water and nitrogen regimes. Linear, nonlinear, and partial least squares(PLS) regression models were fitted to VIs and wavelet functions to estimate CNC and CCC, and were evaluated for their prediction accuracy.UVE was used to eliminate uninformative variables, improve the prediction accuracy of the models, and simplify the PLS regression models(UVE-PLS). For estimating CNC and CCC, the normalized difference vegetation index(NDVI, based on red edge and NIR wavebands) yielded the highest correlation coefficients(r > 0.88). PLS regression models showed the lowest root mean square error(RMSE) among all models. However, PLS regression models required nine VIs and four wavelet functions, increasing their complexity. UVE was used to retain valid spectral parameters and optimize the PLS regression models.UVE-PLS regression models improved validation accuracy and resulted in more accurate CNC and CCC than the PLS regression models. Thus, canopy spectral reflectance integrated with UVE-PLS can accurately reflect maize leaf nitrogen and carbon status.

Online quantitative analysis of soluble solids content in navel oranges using visible-nearinfrared spectroscopy and variable selection methods

Variable selection is applied widely for visible-near infrared(Vis-NIR)spectroscopy analysis of internal quality in fruits.Different spectral variable selection methods were compared for online quantitative analysis of soluble solids content(SSC)in navel oranges.Moving window partial least squares(MW-PLS),Monte Carlo uninformative variables elimination(MC-UVE)and wavelet transform(WT)combined with the MC-UVE method were used to select the spectral variables and develop the calibration models of online analysis of SSC in navel oranges.The performances of these methods were compared for modeling the Vis NIR data sets of navel orange samples.Results show that the WT-MC-UVE methods gave better calibration models with the higher correlation cofficient(r)of 0.89 and lower root mean square error of prediction(RMSEP)of 0.54 at 5 fruits per second.It concluded that Vis NIR spectroscopy coupled with WT-MC-UVE may be a fast and efective tool for online quantitative analysis of SSC in navel oranges.

Why It Is Problematic to Calculate Probabilities of Findings Given Range Null Hypotheses

An important problem with null hypothesis significance testing, as it is normally performed, is that it is uninformative to reject a point null hypothesis [1]. A way around this problem is to use range null hypotheses [2]. But the use of range null hypotheses also is problematic. Aside from the usual issues of whether null hypothesis significance tests can be justified at all, there is an issue that is specific to range null hypotheses. It is not straightforward how to calculate the probability of the data given a range null hypothesis. The traditional way is to use the single point that maximizes the obtained p-value. The Bayesian alternative is to propose a prior probability distribution and integrate across it. Because frequentists and Bayesians disagree about a variety of issues, especially those pertaining to whether it is permissible to assign probabilities to hypotheses, and what gets lost in the shuffle is that the two camps actually come to different answers for the probability of the data given a range null hypothesis. Because the probability of the data given the hypothesis is a precursor for both camps, for drawing conclusions about hypotheses, different values for this probability for the different camps is crucial but seldom acknowledged. The goal of the present article is to bring out the problem in a manner accessible to researchers without strong mathematical or statistical backgrounds.

政治均衡下的环境政策选择和影响

本文设计了一个有不同类型选民、游说团体向参选候选者双方进行政治献金的理论模型,用以考察在企业生产活动对消费者产生负外部性的情况下,政策影响型游说活动所达到的政治均衡的性质以及不同管制政策手段产生的社会福利效果。结论为,在政策影响型游说活动下的政治均衡中,游说团体事实上可以决定候选者的有关环境政策;从社会福利来看,数量管制与价格管制的利弊取决于单位生产所发生的外部性的'边际生产力'。同时,本文还揭示了政治均衡中数量管制与价格管制在四个方面的效果相同。

A variable differential consensus method for improving the quantitative near-infrared spectroscopic analysis

Consensus methods have presented promising tools for improving the reliability of quantitative models in near-infrared(NIR) spectroscopic analysis.A strategy for improving the performance of consensus methods in multivariate calibration of NIR spectra is proposed.In the approach,a subset of non-collinear variables is generated using successive projections algorithm(SPA) for each variable in the reduced spectra by uninformative variables elimination(UVE).Then sub-models are built using the variable subsets and the calibration subsets determined by Monte Carlo(MC) re-sampling,and the sub-model that produces minimal error in cross validation is selected as a member model.With repetition of the MC re-sampling,a series of member models are built and a consensus model is achieved by averaging all the member models.Since member models are built with the best variable subset and the randomly selected calibration subset,both the quality and the diversity of the member models are insured for the consensus model.Two NIR spectral datasets of tobacco lamina are used to investigate the proposed method.The superiority of the method in both accuracy and reliability is demonstrated.