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Uniportal video-assisted thoracoscopic fissureless right upper lobe anterior segmentectomy for inflammatory myofibroblastic tumor:A case report
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作者 Seha Ahn Youngkyu Moon 《World Journal of Clinical Cases》 SCIE 2024年第2期425-430,共6页
BACKGROUND Inflammatory myofibroblastic tumors(IMTs)are exceptionally rare neoplasms with intermediate malignant potential.Surgery is the accepted treatment option,aiming for complete resection with clear margins.CASE... BACKGROUND Inflammatory myofibroblastic tumors(IMTs)are exceptionally rare neoplasms with intermediate malignant potential.Surgery is the accepted treatment option,aiming for complete resection with clear margins.CASE SUMMARY A 39-year-old woman presented with a growing solitary pulmonary nodule measuring 2.0 cm in the right upper lobe(RUL)of the lung.The patient underwent a RUL anterior segmentectomy using uniportal video-assisted thoracoscopy.A preliminary tissue diagnosis indicated malignancy;however,it was later revised to an IMTs.Due to the absence of a minor fissure between the right upper and middle lobes,an alternative resection approach was necessary.Therefore,we utilized indocyanine green injection to aid in delineating the intersegmental plane.Following an uneventful recovery,the patient was discharged on the third postoperative day.Thereafter,annual chest tomography scans were scheduled to monitor for potential local recurrence.CONCLUSION This case underscores the challenges in diagnosing and managing IMTs,showing the importance of accurate pathologic assessments and tailored surgical strategies. 展开更多
关键词 uniportal video-assisted thoracoscopic surgery Fissureless Anterior segmentectomy Inflammatory fibroblastic tumor Case report
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Middle lobe torsion after right upper and lower lobectomy:repositioning of lobar torsion using a3-cm uniportal video-assisted thoracoscopic surgery 被引量:1
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作者 Ruijie Zhang Yixin Cai +2 位作者 Shengling Fu Xiangning Fu Ni Zhang 《Oncology and Translational Medicine》 2017年第1期38-40,共3页
We aimed to describe a method for repositioning of right middle lobar torsion by using a 3-cm uniportal video-assisted thoracoscopic surgery(VATS) approach. Middle lobe torsion occurred after right upper and lower lob... We aimed to describe a method for repositioning of right middle lobar torsion by using a 3-cm uniportal video-assisted thoracoscopic surgery(VATS) approach. Middle lobe torsion occurred after right upper and lower lobectomy in a 74-year-old man. Immediate re-exploratory thoracotomy using the 3-cm uniportal VATS approach was performed. The torsion was corrected, and the lobe was anchored to the anterior chest wall with Prolene stitches. The patient recovered well postoperatively with daily improvements in chest radiographic findings. Follow-up examination was performed using fiberbronchoscopy, which revealed an unobstructed right middle lobe bronchus and sticky yellow sputum. Follow-up chest computed tomography was performed 3 months after the primary surgery and revealed increased expansion of the right middle lobe. We repositioned the right middle lobe successfully by using the 3-cm uniportal VATS approach, but more cases are needed to confirm the feasibility of the approach. Lobectomy remains the primary treatment option for such cases. 展开更多
关键词 LOBE TORSION 3-cm uniportal video-assisted thoracoscopic surgery (VATS)
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Nonintubated uniportal video-assisted thoracoscopic surgery for primary spontaneous pneumothorax 被引量:15
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作者 Shuben Li Fei Cui +5 位作者 Jun Liu Xin Xu Wenlong Shao Weiqiang Yin Hanzhang Chen Jianxing He 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2015年第2期197-202,共6页
Objective: The objective of the current study was to evaluate the feasibility and safety of nonintubated nniportal video-assisted thoracoscopic surgery (VATS) for the management of primary spontaneous pneumothorax ... Objective: The objective of the current study was to evaluate the feasibility and safety of nonintubated nniportal video-assisted thoracoscopic surgery (VATS) for the management of primary spontaneous pneumothorax (PSP). Methods: From November 2011 to June 2013, 32 consecutive patients with PSP were treated by nonintubated uniportal thoracoscopic bullectomy using epidnral anaesthesia and sedation without endotracheal intubation. An incision 2 cm in length was made at the 6th intercostal space in the median axillary line. The pleural space was entered by blunt dissection for placement of a soft incision protector. Instruments were then inserted through the incision protector to perform thoracoscopic bullectomy. Data were collected within a minimum follow-up period of 10 months. Results: The average time of surgery was 49.0 rain (range, 33-65 rain). No complications were recorded. The postoperative feeding time was 6 h. The mean postoperative chest tube drainage and hospital stay were 19.3 h and 41.6 h, respectively. The postoperative pain was mild for 30 patients (93.75%) and moderate for two patients (6.25%). No recurrences ofpneumothorax were observed at follow-up. Conclusions: The initial results indicated that nonintubated uniportal video-assisted thoracoscopic operations are not only technically feasible, but may also be a safe and less invasive alternative for select patients in the management of PSP. This is the first report to include the use of a nonintubated uniportal technique in VATS for such a large number of PSP cases. Further work and development of instruments are needed to define the applications and advantages of this technique. 展开更多
关键词 uniportal video-assisted thoracoscopic surgery (VATS) spontaneous pneumothorax
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Uniportal video-assisted thoracoscopic surgery for complex mediastinal mature teratoma:A case report 被引量:1
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作者 Xue-Lei Hu Dong Zhang Wen-Yong Zhu 《World Journal of Clinical Cases》 SCIE 2021年第26期7870-7875,共6页
BACKGROUND Mediastinal mature teratoma is the most common histological type of primary extragonadal germ cell tumor.In this report,we describe a rare case of giant mature teratoma located primarily in the anterior med... BACKGROUND Mediastinal mature teratoma is the most common histological type of primary extragonadal germ cell tumor.In this report,we describe a rare case of giant mature teratoma located primarily in the anterior mediastinum and causing partial atelectasis of the upper and middle lobes of the right lung,as well as extrinsic compression of the right atrium.CASE SUMMARY A 31-year-old male with a giant mediastinal mature teratoma presented with progressive exertional dyspnea and chest pain for 1 mo.Computed tomography of the chest indicated the diagnosis of anterior mediastinal teratoma.The patient underwent right uniportal anterior approach video-assisted thoracoscopic surgery(VATS).En bloc resection of the giant teratoma,wedge resection of the upper and middle lobes of the right lung,resection of the thymus and partial excision of the pericardium were successfully performed.The pathological diagnosis revealed a mature cystic teratoma with foreign-body reaction that was closely related to the right lung,atrium dextrum,superior vena cava and ascending aorta.An atrophic thymic tissue was also discovered at the external teratoma surface.The patient was discharged on postoperative day 7.CONCLUSION This is the first report of the use of uniportal VATS for complete resection of a teratoma in combination with wedge resection of the right upper and middle lung lobes and partial resection of the pericardium. 展开更多
关键词 uniportal video-assisted thoracoscopic surgery Mediastinal mature teratoma Complex adhesions and infiltration video-assisted thoracoscopic surgery Case report
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Comparison of the body pain and trauma degree between uni-portal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer 被引量:1
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作者 Yang Cao Tao Liu Peng-Fei Wang 《Journal of Hainan Medical University》 2017年第8期106-109,共4页
Objective:To study the differences in the body pain and trauma degree between uniportal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer.Methods:A total of 108 patients with non-s... Objective:To study the differences in the body pain and trauma degree between uniportal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer.Methods:A total of 108 patients with non-small cell lung cancer who received radical operation in our hospital between February 2013 and February 2016 were selected and divided into the uniportal group (n=52) who received uniportal video-assisted thoracoscopic surgery and the three-portal group (n=56) who received three-portal video-assisted thoracoscopic surgery after the operation methods and related laboratory results were reviewed. Before operation and 24 h after operation, the differences in serum levels of pain mediators, oxidative stress indexes and inflammation indexes were compared between the two groups of patients.Results: Before operation, the differences in serum levels of pain mediators, oxidative stress indexes and inflammation indexes were not statistically significant between the two groups of patients. 24 h after operation, serum pain mediators NE, DA and 5-HT levels of observation group were lower than those of control group;oxidative stress indexes MDA and O2- levels were lower than those of control group while SOD and GSH-Px levels were higher than those of control group;inflammation indexes IL-6, IL-8, CRP and TNF-α levels were lower than those of control group.Conclusion: Uniportal video-assisted thoracoscopic surgery for the treatment of lung cancer causes less surgery trauma, and patients' postoperative pain and systemic inflammatory stress response are lighter. 展开更多
关键词 Lung cancer uniportal video-assisted thoracoscopic surgery Three-portal video-assisted thoracoscopic surgery PAIN mediator Oxidative stress Inflammation
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Partial removal of the pulmonary artery in video-assisted thoracic surgery for non-small cell lung cancer 被引量:2
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作者 Keping Xu Zhi Zhang +3 位作者 Jianqiang Zhao Jianfeng Huang Rong Yin Lin Xu 《The Journal of Biomedical Research》 CAS 2013年第4期310-317,共8页
Lobectomy with partial removal of the pulmonary artery in video-assisted thoracic surgery (VATS) currently remains a challenge for thoracic surgeons. We were interested in introducing pulmonary vessel blocking techn... Lobectomy with partial removal of the pulmonary artery in video-assisted thoracic surgery (VATS) currently remains a challenge for thoracic surgeons. We were interested in introducing pulmonary vessel blocking techniques in open thoracic surgery into video-assisted thoracic surgery (VATS) procedures. In this study, we reported a surgical technique simultaneously blocking the pulmonary artery and the pulmonary vein for partial removal of the pulmonary artery under VATS. Seven patients with non-small-cell lung cancer (NSCLC) received lobectomy with partial removal of the pulmonary artery using the technique between December 2007 and March 2012. Briefly, rather than using a small clamp on the distal pulmonary artery to the area of invading cancer, we replaced a vascular clamp with a ribbon and Hem-o-lock clip to block the preserved pulmonary veins so as to prevent back bleeding and yield a better view for surgeons. The mean occlusion time of the pulmonary artery and pulmonary veins were 44.0±10.0 and 41.3±9.7 minutes, respectively. The mean repair time of the pulmonary artery was 25.3±13.7 minutes. No complications occurred. No patients showed abnormal blood flow through the reconstructed vessel. There were no local recurrences on the pulmonary artery. In conclusion, the technique for blocking the pulmonary artery and veins is feasible and safe in VATS and reduces the risk of abrupt intraoperative bleeding and the chance of converting to open thoracotomy, and extends the indications of VATS lobectomy. 展开更多
关键词 video-assisted thoracic surgery (VATS) non-small-cell lung cancer (NSCLC) lobectomy pulmonary artery reconstruction
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Treatment of a densely fused fissure during thoracoscopic right middle lobectomy
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作者 Hiroyuki Koga Kenji Suzuki +3 位作者 Tadaharu Okazaki Kinya Nishimura Geoffrey J. Lane Atsuyuki Yamataka 《Open Journal of Pediatrics》 2013年第2期105-107,共3页
Aim: To report a case of fused fissure between the right upper and middle lobes that we treated using a surgical stapler rather than a Ligasure device for the benefit of creating a better division between the right up... Aim: To report a case of fused fissure between the right upper and middle lobes that we treated using a surgical stapler rather than a Ligasure device for the benefit of creating a better division between the right upper and middle lobes and to effectively seal the lung parenchyma. Case: A 2-year-old girl with congenital cystic adenomatoid malformation of the right middle lobe (RML) was referred to our institution for further management after a series of infections. The vein of the RML, which drains into the superior pulmonary vein, was isolated and divided using endoclips. The bronchus was then exposed and divided using endo-clips. The arteries of the RML could be identified and ligated, allowing a line demarcating the major fissure to be identified and dissected. A stapler device was then used to seal the lung parenchyma and create a division between the right upper and middle lobes. She is currently well after follow-up of 16 months, with no episodes of respiratory distress or recurrence of symptoms. Conclusion: Our technique for dividing the pulmonary vein, then the bronchus, then the pulmonary artery and finally the fused fissure is safe and could be applied whenever fused fissures are encountered during thoracoscopic pulmonary lobectomy. 展开更多
关键词 thoracoscopic surgery pulmonary lobectomy FUSED FISSURE Surgical STAPLER
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Lobectomy by video-assisted thoracoscopic surgery(VATS)for early stage of non-small cell lung cancer 被引量:1
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作者 Min ZHU Xiang-Ning FU Xiaoping CHEN 《Frontiers of Medicine》 SCIE CSCD 2011年第1期53-60,共8页
Video-assisted thoracoscopic surgery(VATS)provides a new approach for treating early-stage lung cancer.Lobectomy by VATS has many advantages over conventional thoracotomy,such as shorter recovery time,less postoperati... Video-assisted thoracoscopic surgery(VATS)provides a new approach for treating early-stage lung cancer.Lobectomy by VATS has many advantages over conventional thoracotomy,such as shorter recovery time,less postoperative pain,and faster resumption of a normal lifestyle.However,there is still much debate on the role of VATS in lobectomy for the treatment of lung cancer.Concerns regarding safety,the extent of mediastinal lymph node dissection,and long-term survival have made some surgeons apprehensive of its validity for lung cancer.In this paper,we review the development of thoracoscopy,the present status of VATS for early stage of non-small cell lung cancer(NSCLC),and comparison between VATS and open thoracotomy in the management of NSCLC. 展开更多
关键词 non-small cell lung cancer video-assisted thoracoscopic surgery lobectomy
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Completely video-assisted thoracoscopic lobectomy versus open lobectomy for non-small cell lung cancer greater than 5 cm:a retrospective study 被引量:10
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作者 Bu Liang Li Yun +5 位作者 Yang Fan Zhao Hui Jiang Guan-chao Li Jian-feng Liu Jun Wang Jun 《Chinese Medical Journal》 SCIE CAS CSCD 2012年第3期434-439,共6页
Background Completely video-assisted thoracoscopic Iobectomy is a reasonable treatment for early-stage non-small-cell lung cancer (NSCLC).At present,the indication for this procedure is stage la and Ib peripheral lu... Background Completely video-assisted thoracoscopic Iobectomy is a reasonable treatment for early-stage non-small-cell lung cancer (NSCLC).At present,the indication for this procedure is stage la and Ib peripheral lung cancer ((〈-)5 cm); however,for larger tumors,it remains controversial whether this surgical technique is comparable to open Iobectomy.This study aimed to evaluate the safety,completeness,and efficacy of thoracoscopic Iobectomy,and to compare this technique with open Iobectomy for the treatment of non-small-cell lung cancer when the tumor's diameter was greater than 5 cm.Methods From May 2001 to April 2011,802 patients underwent a Iobectomy for treatment of non-small-cell lung cancer at our center.In 133 patients,the tumor was 〉 5 cm.There were 98 men and 35 women,median age 63 years (range:29-81 years).We divided the patients into two groups,group V (completely video-assisted thoracoscopic surgery),and group T (open Iobectomy),and evaluated the two groups for age,gender,tumor size,pathological type,location,duration of surgery,blood loss,lymph node dissection,pathological stage,time of drainage,hospitalization,complications,overall survival and recurrence.Results There were 46 cases in group V and 87 cases in group T.Age,gender,tumor size,location,pathological type and stage were similar between the two groups.Group V had shorter operative duration ((186.5±62.8) minutes vs.(256.7±67.5) minutes,P 〈0.001) and reduced bleeding ((218.5±174.6) ml vs.(556.9±187.2) ml,P 〈0.001).There were no significant differences between the two groups in complications,lymph node dissection,time of drainage and hospitalization.The recurrence between the two groups was equivalent (2.4% vs.3.8%,P=0.670).The overall survival at 1,2 and 3 years was 95.1%,81.6% and 69.6% for group V and 88.3%,78.8% and 64.0% for group T.Kaplan-Meier survival curves showed that there was no significant differences between the two groups (P=0.129).Conclusions Completely video-assisted thoracoscopic lobectomy was similar to open lobectomy in safety,completeness,and efficacy,but had a shorter operative duration,and reduced bleeding.This is a minimally invasive procedure that is feasible for a subset of non-small-cell lung cancer patients with tumor size 〉 5 cm. 展开更多
关键词 minimally invasive surgery lobectomy completely video-assisted thoracoscopic lobectomy open lobectomy non-small-cell lung cancer
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单孔法电视辅助胸腔镜肺叶切除术对肺结核患者免疫细胞水平、VAS评分及并发症的影响 被引量:1
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作者 张玉宝 赵宇飞 魏子昂 《中国医学创新》 CAS 2024年第12期61-65,共5页
目的:分析单孔法电视辅助胸腔镜(uniportal video-assisted thoracoscopic surgery,UVTAS)肺叶切除术对肺结核患者免疫细胞水平、视觉模拟评分法(VAS)评分及并发症的影响。方法:选取2020年1月—2022年1月在内蒙古自治区第四医院接受UVTA... 目的:分析单孔法电视辅助胸腔镜(uniportal video-assisted thoracoscopic surgery,UVTAS)肺叶切除术对肺结核患者免疫细胞水平、视觉模拟评分法(VAS)评分及并发症的影响。方法:选取2020年1月—2022年1月在内蒙古自治区第四医院接受UVTAS肺叶切除术的100例肺结核患者,随机分为对照组(n=50)和研究组(n=50)。对照组接受双操作孔胸腔镜手术,研究组接受UVTAS肺叶切除术。比较两组免疫细胞水平、VAS评分及并发症的变化。结果:两组免疫细胞水平时间、组间、交互效应比较,差异均有统计学意义(P<0.05)。术后1周,研究组CD3^(+)T淋巴细胞、CD4^(+)T淋巴细胞均显著高于对照组,CD8^(+)T淋巴细胞低于对照组(P<0.05);术后1个月,两组免疫细胞水平,差异均无统计学意义(P>0.05)。术后1周,两组VAS评分均比术后1 d低(P<0.05),且研究组更低(P<0.05)。研究组的术后并发症发生率显著低于对照组(P<0.05)。结论:UVTAS肺叶切除术能够提高肺结核患者的免疫功能,减轻术后疼痛及并发症。 展开更多
关键词 单孔法电视辅助胸腔镜 肺叶切除 肺结核 免疫细胞水平 并发症
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胸腔镜肺叶切除联合纵隔淋巴结清扫治疗ⅢA期非小细胞肺癌的疗效
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作者 边永霞 张继朋 +2 位作者 李桂珍 姜飞娥 甘桐菲 《保健医学研究与实践》 2024年第5期78-84,共7页
目的探讨胸腔镜肺叶切除(VATS)联合纵隔淋巴结清扫(MLND)治疗ⅢA期非小细胞肺癌(NSCLC)的疗效,以期为NSCLC的临床治疗提供参考。方法回顾性分析空军军医大学第二附属医院2017年6月-2021年12月收治的ⅢA期NSCLC患者的临床资料,采用整群... 目的探讨胸腔镜肺叶切除(VATS)联合纵隔淋巴结清扫(MLND)治疗ⅢA期非小细胞肺癌(NSCLC)的疗效,以期为NSCLC的临床治疗提供参考。方法回顾性分析空军军医大学第二附属医院2017年6月-2021年12月收治的ⅢA期NSCLC患者的临床资料,采用整群随机抽样法从开胸肺叶切除联合MLND治疗患者中选取57例纳入对照组,从VATS联合MLND治疗患者中选取63例纳入观察组。比较2组患者治疗前及治疗后6个月的血清肿瘤标志物水平、肺功能指标,近期实体瘤疗效,随访2年生存情况以及治疗后6个月内的并发症发生情况。结果观察组患者手术时间长于对照组,淋巴结清扫数目多于对照组,差异均有统计学意义(P<0.05);观察组患者引流时间、住院时间短于对照组,术中出血量小于对照组,差异均有统计学意义(P<0.05)。治疗前,2组患者癌胚抗原(CEA)、糖类抗原50(CA50)、细胞角质蛋白19片段抗原21-1(CYFRA21-1)及鳞癌相关抗原(SCC)水平比较,差异均无统计学意义(P>0.05);治疗后6个月,2组患者血清CEA、CA50、CYFRA21-1及SCC水平均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组患者血清最大通气量(MVV)、用力肺活量(FVC)及第1秒用力呼气容积(FEV1)水平比较,差异均无统计学意义(P>0.05);治疗后6个月,2组患者MVV、FVC及FEV1水平均低于治疗前,但观察组均高于对照组,差异均有统计学意义(P<0.05)。治疗后6个月,2组患者疾病控制率(DCR)比较,差异无统计学意义(P>0.05);观察组患者客观缓解率(ORR)高于对照组,差异有统计学意义(P<0.05);不同TNM分期患者的DCR和ORR组间比较,差异均无统计学意义(P>0.05)。2组患者随访2年生存率比较,差异无统计学意义(χ^(2)=2.409,P=0.121);观察组患者无进展生存期(PFS)大于对照组,差异有统计学意义(t=2.842,P=0.005);2组患者总生存时间(OS)比较,差异无统计学意义(t=0.308,P=0.758)。观察组患者治疗后6个月内的并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论针对ⅢA期NSCLC患者,采用VATS联合MLND治疗的近、远期疗效理想,有助于恢复患者肺部功能,且并发症发生风险可控,这为临床治疗提供多种可替代选择,建议临床根据患者实际情况,在医患充分沟通后选择最佳治疗方案。 展开更多
关键词 非小细胞肺癌 胸腔镜肺叶切除 纵隔淋巴结清扫 生存率 肺功能 肿瘤标志物
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A Matched Comparison Study of Uniportal Versus Triportal Thoracoscopic Lobectomy and Sublobectomy for Early-stage Nonsmall Cell Lung Cancer 被引量:12
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作者 Ju-Wei Mu Shu-Geng Gao Qi Xue Jun Zhao Ning Li Kun Yang Kai Su Zhu-Yang Yuan Jie He 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第20期2731-2735,共5页
Background: Both uniportal and triportal thoracoscopic lobectomy and sublobectomy are feasible for early-stage non-small cell lung cancer (NSCLC). The aim of this study was to compare the perioperative outcomes of ... Background: Both uniportal and triportal thoracoscopic lobectomy and sublobectomy are feasible for early-stage non-small cell lung cancer (NSCLC). The aim of this study was to compare the perioperative outcomes of uniportal and triportal thoracoscopic Iobectomy and sublobectomy for early-stage NSCLC. Methods: A total of 405 patients with lung lesions underwent thoracoscopic lobectomy or sublobectomy through a uniportal or triportal procedure in approximately 7-month period (From November 2014 to May 2015). A propensity-matched analysis, incorporating preoperative variables, was used to compare the short-term outcomes of patients who received uniportal or triportal thoracoscopic lobectomy and sublobectomy. Results: Fifty-eight patients underwent uniportal and 347 patients underwent triportal pulmonary resection. The conversion rate for uniportal and triportal procedure was 3.4% (2/58) and 2.3% (8/347), respectively. The complication rate for uniportal and triportal procedure was 10.3% and 9.5%, respectively. There was no perioperative death in either group. Most patients had early-stage NSCLC in both groups (uniportal: 45/47, 96%; triportal: 313/343, 91%). Propensity score-matching analysis demonstrated no significant differences in operation time, intraoperative blood loss, numbers of dissected lymph nodes, number of stations of lymph node dissected, duration of chest tube, and complication rate between uniportal and triportal group for early-stage NSCLC. However, the duration of postoperative hospitalization was longer in the uniportal group (6.83 ± 4.17 vs. 5.42 ± 1.86 d, P = 0.036) compared with the triportal group. Conclusions: Uniportal thoracoscopic lobectomy and sublobectomy is safe and feasible, with comparable short-term outcomes with triportal thoracoscopic pulmonary resection. Uniportal lobectomy and sublobectomy lead to similar cure rate as triportal Iobectomy and sublobectomy for early NSCLC. 展开更多
关键词 Early-stage Nonsmall Cell Lung Cancer lobectomy Sublobectomy uniportal video-assisted thoracoscopic surgery
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经肋间单孔胸腔镜肺叶切除术联合消癌平对非小细胞肺癌患者miR-210和miR-101表达的影响 被引量:8
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作者 王维新 何国丽 +3 位作者 张剑锋 付红艳 左晶晶 任宏玲 《中国药业》 CAS 2023年第5期97-100,共4页
目的探讨经肋间单孔胸腔镜(IUVATS)肺叶切除术联合消癌平治疗非小细胞肺癌(NSCLC)的临床疗效,以及对患者微小RNA210(miR-210)和微小RNA101(miR-101)表达水平的影响。方法选取医院2020年4月至2021年4月收治的NSCLC患者118例,按随机数字... 目的探讨经肋间单孔胸腔镜(IUVATS)肺叶切除术联合消癌平治疗非小细胞肺癌(NSCLC)的临床疗效,以及对患者微小RNA210(miR-210)和微小RNA101(miR-101)表达水平的影响。方法选取医院2020年4月至2021年4月收治的NSCLC患者118例,按随机数字表法分为对照组和观察组,各59例。对照组患者以IUVATS肺叶切除术治疗,并辅以PE(顺铂+依托泊苷)化疗方案;观察组患者在对照组治疗基础上加用消癌平注射液。以21 d为1个化疗周期,两组均连续治疗4个周期。结果观察组患者的客观缓解率(ORR)为77.97%,疾病控制率(DCR)为88.14%,显著高于对照组的61.02%和71.19%(P<0.05)。治疗后,观察组患者的肿瘤标志物[糖类抗原199(CA199)、糖类抗原153(CA153)、人细胞角蛋白21-1片段(CYFRA21-1)]均显著低于对照组(P<0.05);T淋巴细胞亚群CD_(3)^(+),CD_(4)^(+),CD_(4)^(+)/CD_(8)^(+)均显著高于对照组,CD_(8)^(+)显著低于对照组(P<0.05);miR-210和miR-101水平均显著低于对照组(P<0.05)。治疗期间,观察组和对照组患者的不良反应发生率相当(18.64%比13.56%,P>0.05)。结论IUVATS肺叶切除术联合消癌平治疗NSCLC的临床疗效良好,能降低患者的肿瘤标志物水平,增强免疫力,抑制miR-210和miR-101的表达,且治疗安全性较好。 展开更多
关键词 非小细胞肺癌 经肋间单孔胸腔镜 肺叶切除术 消癌平 微小RNA210 微小RNA101 临床疗效
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Posterior mediastinal extralobar pulmonary sequestration misdiagnosed as a neurogenic tumor:A case report
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作者 Hong-Jie Jin Yue Yu +1 位作者 Wei He Yun Han 《World Journal of Clinical Cases》 SCIE 2022年第26期9340-9347,共8页
BACKGROUND Pulmonary sequestration-both intralobar and extralobar-is a rare congenital developmental malformation.Extralobar pulmonary sequestrations(EPS)have their own pleura but are separated from the bronchus and u... BACKGROUND Pulmonary sequestration-both intralobar and extralobar-is a rare congenital developmental malformation.Extralobar pulmonary sequestrations(EPS)have their own pleura but are separated from the bronchus and usually occur in the left lung.They are mainly found mainly between the lower lobe and the mediastinum.EPS is rarely found within the mediastinum itself,even rarer so in the posterior mediastinum.CASE SUMMARY We report the case of a 27-year-old man who was misdiagnosed with a neurogenic tumor based on preoperative contrast-enhanced computed tomography(CT)and magnetic resonance imaging findings.Contrast-enhanced chest CT revealed a posterior mediastinal mass measuring 1.2 cm×1.4 cm×3.3 cm,which consisted of some cystic areas and showed slight enhancement.The mass was in the 11th paravertebral region and attached to the 11th thoracic vertebra behind the descending aorta in the posterior mediastinum.An arteriole originating from the intercostal artery and a vein originating directly from the hemiazygos vein were found in the pedicle of the mass.The mass was resected in a uniport videoassisted thoracoscopic surgery.During the operation,the pyramid-shaped mass appeared well-encapsulated.Postoperative histopathology established a diagnosis of EPS.One month later,a follow-up CT of the thorax showed good recovery.CONCLUSION Although EPS rarely occurs in the posterior mediastinum,its diagnosis should be considered when posterior mediastinal tumors are suspected. 展开更多
关键词 Posterior mediastinal mass pulmonary sequestration Extralobar pulmonary sequestration Congenital malformation video-assisted thoracoscopic surgery Case report
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Commentary on impact of pulmonary function on robotic pulmonary resection
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作者 Anthony Le Matheus Carelli +1 位作者 Allen Guo Christopher Cao 《Laparoscopic, Endoscopic and Robotic Surgery》 2021年第3期93-94,共2页
Buitrago and colleagues should be commended on an excellent case report on the effective use of the robotic platform for a successful minimally invasive left lower lobectomy for a patient with biopsy proven squamous c... Buitrago and colleagues should be commended on an excellent case report on the effective use of the robotic platform for a successful minimally invasive left lower lobectomy for a patient with biopsy proven squamous cell carcinoma.1 Despite a predicted postoperative forced expiratory volume in one second(ppoFEV1)of 23%and a preoperative diffusing capacity for carbon monoxide(DLCO)of 21%,the patient underwent a lobectomy without any intraoperative complications or evidence of disease at 15 months follow-up.Lymph node sampling was performed from 5 stations.The postoperative length of staywas not clearly stated.The authors made several interesting points about the impact of pulmonary function on postoperative outcomes,the oncological efficacy of lobectomy versus sublobar resections,and merits of roboticassisted thoracoscopic surgery(RATS)versus thoracotomy and conventional video-assisted thoracoscopic surgery(VATS).We would like to discuss these points in further detail based on the available evidence in the current literature. 展开更多
关键词 pulmonary function Lung cancer Robot-assisted thoracoscopic surgery lobectomy
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单孔胸腔镜同期治疗双肺多发肺结节的效果分析 被引量:3
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作者 袁晓龙 闫云龙 +1 位作者 刘建 王臻 《中国临床新医学》 2023年第5期497-500,共4页
目的分析单孔胸腔镜同期治疗双肺多发肺结节的效果。方法回顾性分析2020年1月至2021年12月在东营市中医院(东营市胜利医院)胸心外科实施单孔胸腔镜下肺叶/亚肺叶切除同期治疗双肺多发肺结节24例患者的临床资料。其中男15例,女9例;年龄51... 目的分析单孔胸腔镜同期治疗双肺多发肺结节的效果。方法回顾性分析2020年1月至2021年12月在东营市中医院(东营市胜利医院)胸心外科实施单孔胸腔镜下肺叶/亚肺叶切除同期治疗双肺多发肺结节24例患者的临床资料。其中男15例,女9例;年龄51~79(64.5±8.4)岁。一侧肺叶+一侧亚肺叶切除3例,双侧亚肺叶切除21例。结果所有患者顺利完成手术并出院。手术时间90~254(162.1±50.9)min,术后住院时间4~13(7.1±2.3)d,术后胸腔引流带管时间2~4(2.8±0.8)d。术后并发症肺部感染2例,刀口愈合不良1例,咳嗽不适4例,术后憋喘不适4例。结论单孔胸腔镜同期治疗双肺多发肺结节可行性良好,治疗效果满意。 展开更多
关键词 双侧同期 单孔胸腔镜 肺结节
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Completely thoracoscopic lobectomy for the surgical management of bronchiectasis 被引量:16
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作者 ZHOU Zu-li ZHAO Hui LI Yun LI Jian-feng JIANG Guan-chao WANG Jun 《Chinese Medical Journal》 SCIE CAS CSCD 2013年第5期875-878,共4页
Background The feasibility of completing a Iobectomy by completely video-assisted thoracoscopic surgery (cVATS) in the management of bronchiectasis is unclear. By retrospectively comparing the outcomes from the Iobe... Background The feasibility of completing a Iobectomy by completely video-assisted thoracoscopic surgery (cVATS) in the management of bronchiectasis is unclear. By retrospectively comparing the outcomes from the Iobectomies that used thoracotomy vs. cVATS, we determined the appropriateness of the minimally invasive cVATS approach in the management of bronchiectasis. Methods Between June 2001 and October 2010, 60 patients with bronchiectasis underwent surgery, of which 56 Iobectomies were performed. All Iobectomies were carried out by either thoracotomy or cVATS approach. Pulmonary vessels and bronchi were manipulated by ligation or stapler in the thoracotomy group, while they were dissected by endo-cutters in the cVATS group. Results There were 21 patients in the thoracotomy group and 35 patients in the cVATS group. Two cVATS patients (5.7%) converted. The difference in operation time, chest tube duration, lengths of hospitalization, and morbidity were not significantly different between the two groups (P 〉0.05). The blood loss was less in the cVATS group (P=0.015). A total of 52.4% and 62.9% of patients were postoperatively asymptomatic in the thoracotomy and cVATS groups respectively, and symptomatic improvement was obtained in 38.1% patients by thoracotomy vs. 31.4% patients by cVATS. Conclusion cVATS Iobectomy is safe and effective for the management of bronchiectasis, especially for the patients with localized lesions. 展开更多
关键词 video-assisted thoracoscopic surgery lobectomy BRONCHIECTASIS
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模块化“动脉、支气管、静脉、肺裂”顺序无肺裂技术在单孔胸腔镜右肺上叶切除术中的应用
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作者 王彪 胡智 +2 位作者 宋琦 张登国 蒲江涛 《中国微创外科杂志》 CSCD 北大核心 2023年第8期567-570,共4页
目的探讨模块化“动脉、支气管、静脉、肺裂”顺序(简称ABVF,A尖前支动脉→B支气管→V静脉→F肺裂)无肺裂技术(fissureless technique)在单孔胸腔镜右肺上叶切除术中的应用价值。方法回顾性分析2021年6~12月单一医疗组行单孔胸腔镜右肺... 目的探讨模块化“动脉、支气管、静脉、肺裂”顺序(简称ABVF,A尖前支动脉→B支气管→V静脉→F肺裂)无肺裂技术(fissureless technique)在单孔胸腔镜右肺上叶切除术中的应用价值。方法回顾性分析2021年6~12月单一医疗组行单孔胸腔镜右肺上叶切除术30例资料,采用ABVF为主线的模块化无肺裂技术完成。结果手术均顺利完成,无中转开胸或增加孔手术。手术时间40~168(105.3±30.3)min,术中出血量10~120(38.7±31.2)ml,术后胸腔引流时间2~5(2.9±0.8)d,术后住院时间2~7(4.0±1.1)d。术后心律失常1例,无肺部感染、肺不张、漏气。术后1个月随访,1例切口愈合不良。结论采用模块化ABVF无肺裂技术行单孔胸腔镜右肺上叶切除术安全可行,可以成为右肺上叶切除术的优选方案。 展开更多
关键词 无肺裂技术 单孔胸腔镜 右肺上叶切除术
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不同胸腔镜手术切除方式治疗早期肺癌肺部小结节患者的临床效果
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作者 周羽 《中外医学研究》 2023年第19期125-128,共4页
目的:对比不同胸腔镜手术切除方式治疗早期肺癌肺部小结节患者的临床效果。方法:回顾性选取2019年1月—2020年12月于常熟市中医院胸心外科治疗的119例早期肺癌肺部小结节患者临床资料。根据手术不同切除方式将其分为肺楔形切除组(n=40)... 目的:对比不同胸腔镜手术切除方式治疗早期肺癌肺部小结节患者的临床效果。方法:回顾性选取2019年1月—2020年12月于常熟市中医院胸心外科治疗的119例早期肺癌肺部小结节患者临床资料。根据手术不同切除方式将其分为肺楔形切除组(n=40)、肺段切除组(n=39)、肺叶切除组(n=40)。三组均给予胸腔镜手术。肺叶切除组给予肺叶切除胸腔镜手术,肺段切除组给予肺段切除胸腔镜手术,肺楔形切除组给予肺楔形切除胸腔镜手术。比较三组围手术期指标、并发症、复发及死亡情况。结果:肺段切除组手术时间、术后住院时间均短于肺叶切除组,引流总量少于肺叶切除组,视觉模拟评分法(VAS)评分低于肺叶切除组;肺楔形切除组手术时间短于肺叶切除组和肺段切除组,总费用和引流总量均少于肺叶切除组和肺段切除组,置管时间和术后住院时间均短于肺叶切除组,VAS评分低于肺叶切除组和肺段切除组,差异有统计学意义(P<0.05)。三组术后并发症发生率比较,差异无统计学意义(P>0.05)。三组术后1年无死亡及复发情况。结论:在早期肺癌肺部小结节患者的治疗中,肺楔形切除和肺段切除这两种术式创伤小,有助于患者术后康复,以肺楔形切除术更优。相较于前两种,肺叶切除术创伤大,术后住院时间长,三种手术方式并发症无明显差异。 展开更多
关键词 胸腔镜手术 肺癌 肺楔形切除 肺段切除 肺叶切除
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单孔全胸腔镜手术:单中心连续106例回顾分析 被引量:21
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作者 王光锁 王正 +4 位作者 王健 饶展鹏 乔坤 杨林 林少霖 《中国内镜杂志》 CSCD 北大核心 2014年第2期118-123,共6页
摘要:目的总结单中心单孔全胸腔镜手术(cVATS)的临床结果,并初步分析手术要点、安全性及可行性。方法2012年6月~2013年11月,该科完成106例单孔cVATS手术。肺楔形切除62例,胸膜、纵隔肿瘤切除19例,纵隔淋巴结活检11例,肺叶切除1... 摘要:目的总结单中心单孔全胸腔镜手术(cVATS)的临床结果,并初步分析手术要点、安全性及可行性。方法2012年6月~2013年11月,该科完成106例单孔cVATS手术。肺楔形切除62例,胸膜、纵隔肿瘤切除19例,纵隔淋巴结活检11例,肺叶切除13例(14个肺叶),其中9例肺癌根治术,肺段切除1例。观察其临床结果,并总结单孔cVATS手术技术要点。结果全组患者术后无肺不张、肺部感染、出血及肺栓塞等严重并发症,无围手术期死亡。简单胸腔手术无中转,肺叶切除中转开胸2例,中转(双孔腔镜或开胸)率14.3%(2/14)。肺叶切除组平均手术时间191(90~420)min;术中平均出血381(5—3500)mL;术后平均引流时间2.3(1~6)d;术后平均住院5(3~10)d;肺癌患者清扫平均淋巴结数16.4(6~31)枚,淋巴结站数5.2(4~6)站。结论对于熟练掌握双孔cVATS技术的胸外科腔镜医生,单孔cVATS肺叶切除术技术可行,安全,术后胸病更轻。还需更多病例积累,有必要通过合理安排学习曲线缩短该过程。 展开更多
关键词 胸腔镜 单孔 肺叶切除术 肺癌 术后疼痛
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