Register transfer level mapping (RTLM) algorithm for technology mapping at RT level is presented,which supports current design methodologies using high level design and design reuse.The mapping rules implement a sou...Register transfer level mapping (RTLM) algorithm for technology mapping at RT level is presented,which supports current design methodologies using high level design and design reuse.The mapping rules implement a source ALU using target ALU.The source ALUs and the target ALUs are all represented by the general ALUs and the mapping rules are applied in the algorithm.The mapping rules are described in a table fashion.The graph clustering algorithm is a branch and bound algorithm based on the graph formulation of the mapping algorithm.The mapping algorithm suits well mapping of regularly structured data path.Comparisons are made between the experimental results generated by 1 greedy algorithm and graphclustering algorithm,showing the feasibility of presented algorithm.展开更多
Polyamines, putrescine (PUT), spermidine (SPD) and spermine (SPM) are implicated in plants’ responses under conditions of abiotic stress. Previous research in other crops has indicated that polyamines and changes in ...Polyamines, putrescine (PUT), spermidine (SPD) and spermine (SPM) are implicated in plants’ responses under conditions of abiotic stress. Previous research in other crops has indicated that polyamines and changes in their concentrations are associated with drought tolerance under conditions of water-deficit stress;however, no information exists on cotton (Gossypium hirsutum L.). Growth chamber experiments were conducted with two cotton cultivars differing in drought tolerance, ST5288B2F (drought-sensitive) and Siokra L23 (drought-tolerant) in order to investigate the distribution of free polyamines, the effect of water-deficit stress on the polyamine metabolism of cotton reproductive units and their subtending leaves as well as the possible relationship between polyamines and drought tolerance in cotton. Our results showed that cotton ovaries contained significantly higher levels of total free polyamines compared to their subtending leaves under both control and water stress conditions. Water-deficit stress significantly increased PUT concentrations in ST5288B2F, while SPM levels significantly decreased in Siokra L23. The results indicated that water-deficit stress significantly affected cotton polyamine metabolism in reproductive structures and their subtending leaves;however, no clear relationship between drought-tolerance and changes in polyamine accumulation was established. Further research is needed to elucidate the mechanism according to which water-deficit stress affects polyamine metabolism.展开更多
The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells...The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.展开更多
Unit nurse managers in Malawi experience many challenges in the course of performing their roles. This affects their performance and service delivery including the quality of nursing care to patients. This study was c...Unit nurse managers in Malawi experience many challenges in the course of performing their roles. This affects their performance and service delivery including the quality of nursing care to patients. This study was conducted to determine the factors that hindered performance of unit managers in relation to expected quality of nursing services at two referral facilities (Kamuzu and Queen Elizabeth Central hospitals) in Malawi. These two central hospitals have the same structural settings and both offer specialized tertiary health services. A quantitative descriptive design was used to guide the planning and implementation of the study. Purposive sampling was used to select the two major hospitals in Malawi and all available 37 unit nurse managers during the time of the study at the two hospitals participated in the study. Data were collected using semi-structured questionnaires after seeking consent from the participants and were analyzed using SPSS version 16.0. The major roles identified by the unit managers were supervision (75.6%, n = 28) and coordination (70.3%, n = 26). Other roles such as team leader, liaison officer, research allocator, monitor and facilitator were rated by very few participants. Findings of the study showed that performance of unit nurse managers was affected by inadequate material (86.4%, n = 32) and human resources (94.5%, n = 35) and lack of managerial skills (5.4%, n = 2). In addition, the unit managers perceived their role to be stressful (38.9%, n = 14) and challenging (47.2%, n = 17). Therefore, there is a need to provide adequate material and human resources to the wards of the two central hospitals to enable the unit managers perform their duties efficiently.展开更多
BACKGROUND Ammonia is a normal constituent of body fluids and is found mainly through the formation of urea in the liver.Blood levels of ammonia must remain low as even slightly elevated concentrations(hyperammonemia)...BACKGROUND Ammonia is a normal constituent of body fluids and is found mainly through the formation of urea in the liver.Blood levels of ammonia must remain low as even slightly elevated concentrations(hyperammonemia)are toxic to the central nervous system.AIM To examine the relationship between the incidence of non-hepatic hyperammonemia(NHH)and the prognosis of patients who were admitted to the intensive care unit(ICU).METHODS This is a prospective,observational and single-center study.A total of 364 patients who were admitted to the ICU from November 2019 to February 2020 were initially enrolled.Changes in the levels of blood ammonia at the time of ICU admission and after ICU admission were continuously monitored.In addition,factors influencing the prognosis of NHH patients were analyzed.RESULTS A total of 204 patients who met the inclusion criteria were enrolled in this study,including 155 NHH patients and 44 severe-NHH patients.The incidence of NHH and severe-NHH was 75.98% and 21.57%,respectively.Patients with severe-NHH exhibited longer length of ICU stay and higher Acute Physiologic Assessment and Chronic Health Evaluation and Sequential Organ Failure Assessment scores compared to those with mild-NHH and non-NHH.Glasgow Coma Scale scores of patients with severe-NHH were than those of non-NHH patients.In addition,the mean and initial levels of ammonia in the blood might be helpful in predicting the prognosis of NHH.CONCLUSION High blood ammonia level is frequent among NHH patients admitted to the ICU,which is related to the clinical characteristics of patients.Furthermore,the level of blood ammonia may be helpful for prognosis prediction.展开更多
On the basis of the comparison data of Stage II of the tunnel site leveling project at Hutubi seismic station and the observation data of Stage IV of the site cross fault leveling project at Hutubi and the level obser...On the basis of the comparison data of Stage II of the tunnel site leveling project at Hutubi seismic station and the observation data of Stage IV of the site cross fault leveling project at Hutubi and the level observation data from the cross fault survey lines in Dafeng from 1987 to 2012,this paper analyses the variation rates of the tunnel site leveling observation results and the difference of annual change rates of the cross fault level observations at Hongshan seismic station in Hutubi. This paper concludes the reliability of the Ni004 optical level used by the station and puts forward a proposal based on the analysis. This paper also explores the cross fault leveling research on the ground deformation in the region concerned on the basis of the historical observation of the cross fault level at Dafeng and the comparison results of the tunnel site leveling observation in Hutubi.展开更多
Current minimally invasive interventions for ureteric stones involve either ESWL or Ureteroscopy and stone localization is mandatory for successful treatment in both. Objectives: To avoid doing KUB radiograph before E...Current minimally invasive interventions for ureteric stones involve either ESWL or Ureteroscopy and stone localization is mandatory for successful treatment in both. Objectives: To avoid doing KUB radiograph before ESWL routinely by correlating the stone attenuation value on CT KUB with stone visualization at fluoroscopy. Methods: This is a prospective cross sectional hospital based, Multicentric study carried out on 1010 patients with ureteric stones in Sudan from August 2014 to March 2016. Results: Mean stone density in HU was 704.45 ± 300 (SD) ranging (81 - 1873) HU. All of the stones were localized using fluoroscopy and only 26.5% of them were not seen under fluoroscopy. I.V contrast was used mostly, and also mainly in the upper ureter. More than 80% of the application of contrast through the ureteric catheter was in the lower ureteric stones. 91.2% of patients with stone density ≤ 400 HU failed to appear at fluoroscopy and therefore 400 HU attenuation value can be used as a cut-off level to request doing KUB before ESWL and Ureteroscopy. Conclusion: the ureteric stones with density ≤400 HU the likelihood of being non-visualized at fluoroscopy is 91.2% therefore if the stone has ≤400 HU at CT KUB it is mandatory to do KUB before treatment above that it is most likely to be seen at fluoroscopy and no need to request KUB for them before ESWL or URS. 1) Inclusion Criteria: All patients diagnosed by CT scan to have ureteric stones for ESWL or Ureteroscopy. 2) Exclusion Criteria: Patients for whom treatment of ureteric stone by ESWL or ureteroscopy is not indicated like severe infection or poor kidney function where nephrectomy is needed.展开更多
On July 9,the 2018 United Nations High Level Political Forum on Sustainable Development was grandly opened at the United Nations Headquarters in New York.China NGO Network for International Exchanges (CNIE)organized a...On July 9,the 2018 United Nations High Level Political Forum on Sustainable Development was grandly opened at the United Nations Headquarters in New York.China NGO Network for International Exchanges (CNIE)organized a number of social organizations in China to attend the forum,held a theme seminar,and participated in the photo exhibition of the forum.展开更多
In recent years, graphical processing unit (GPU)-accelerated intelligent algorithms have been widely utilized for solving combination optimization problems, which are NP-hard, These intelligent algorithms involves a...In recent years, graphical processing unit (GPU)-accelerated intelligent algorithms have been widely utilized for solving combination optimization problems, which are NP-hard, These intelligent algorithms involves a common operation, namely reduction, in which the best suitable candidate solution in the neighborhood is selected. As one of the main procedures, it is necessary to optimize the reduction on the GPU. In this paper, we propose an enhanced warp-based reduction on the GPU. Compared with existing block-based reduction methods, our method exploit efficiently the potential of implementation at warp level, which better matches the characteristics of current GPU architecture. Firstly, in order to improve the global memory access performance, the vectoring accessing is utilized. Secondly, at the level of thread block reduction, an enhanced warp-based reduction on the shared memory are presented to form partial results. Thirdly, for the configuration of the number of thread blocks, the number of thread blocks can be obtained by maximizing the size of thread block and the maximum size of threads per stream multi-processor on GPU. Finally, the proposed method is evaluated on three generations of NVIDIA GPUs with the better performances than previous methods.展开更多
为了进一步降低园区综合能源系统(park-level integrated energy system,PIES)碳排放量,优化热电联产(combined heat and power,CHP)机组出力的灵活性,提出一种考虑改进阶梯型碳交易和CHP热电灵活输出的PIES低碳经济调度策略。首先,将...为了进一步降低园区综合能源系统(park-level integrated energy system,PIES)碳排放量,优化热电联产(combined heat and power,CHP)机组出力的灵活性,提出一种考虑改进阶梯型碳交易和CHP热电灵活输出的PIES低碳经济调度策略。首先,将遗传算法与模糊控制相结合,设计一种遗传模糊碳交易参数优化器,从而对现有阶梯型碳交易机制进行改进,实现该机制参数的自适应变化;其次,在传统CHP中加入卡琳娜(Kalina)循环与电锅炉(electricboiler,EB),构造CHP热电灵活输出模型,以同时满足电、热负荷的不同需求;然后,提出一种柔性指标——电、热输出占比率,进而计算出电、热输出占比率区间,以衡量CHP运行灵活性;最后,将改进阶梯型碳交易机制和CHP热电灵活输出模型协同优化,以系统运行成本和碳交易成本之和最小为目标,构建PIES低碳经济优化模型。算例分析表明,所提策略可有效降低经济成本和碳排放量,同时还可扩展CHP灵活输出调节范围,能够为PIES低碳经济调度提供参考。展开更多
文摘Register transfer level mapping (RTLM) algorithm for technology mapping at RT level is presented,which supports current design methodologies using high level design and design reuse.The mapping rules implement a source ALU using target ALU.The source ALUs and the target ALUs are all represented by the general ALUs and the mapping rules are applied in the algorithm.The mapping rules are described in a table fashion.The graph clustering algorithm is a branch and bound algorithm based on the graph formulation of the mapping algorithm.The mapping algorithm suits well mapping of regularly structured data path.Comparisons are made between the experimental results generated by 1 greedy algorithm and graphclustering algorithm,showing the feasibility of presented algorithm.
文摘Polyamines, putrescine (PUT), spermidine (SPD) and spermine (SPM) are implicated in plants’ responses under conditions of abiotic stress. Previous research in other crops has indicated that polyamines and changes in their concentrations are associated with drought tolerance under conditions of water-deficit stress;however, no information exists on cotton (Gossypium hirsutum L.). Growth chamber experiments were conducted with two cotton cultivars differing in drought tolerance, ST5288B2F (drought-sensitive) and Siokra L23 (drought-tolerant) in order to investigate the distribution of free polyamines, the effect of water-deficit stress on the polyamine metabolism of cotton reproductive units and their subtending leaves as well as the possible relationship between polyamines and drought tolerance in cotton. Our results showed that cotton ovaries contained significantly higher levels of total free polyamines compared to their subtending leaves under both control and water stress conditions. Water-deficit stress significantly increased PUT concentrations in ST5288B2F, while SPM levels significantly decreased in Siokra L23. The results indicated that water-deficit stress significantly affected cotton polyamine metabolism in reproductive structures and their subtending leaves;however, no clear relationship between drought-tolerance and changes in polyamine accumulation was established. Further research is needed to elucidate the mechanism according to which water-deficit stress affects polyamine metabolism.
文摘The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.
文摘Unit nurse managers in Malawi experience many challenges in the course of performing their roles. This affects their performance and service delivery including the quality of nursing care to patients. This study was conducted to determine the factors that hindered performance of unit managers in relation to expected quality of nursing services at two referral facilities (Kamuzu and Queen Elizabeth Central hospitals) in Malawi. These two central hospitals have the same structural settings and both offer specialized tertiary health services. A quantitative descriptive design was used to guide the planning and implementation of the study. Purposive sampling was used to select the two major hospitals in Malawi and all available 37 unit nurse managers during the time of the study at the two hospitals participated in the study. Data were collected using semi-structured questionnaires after seeking consent from the participants and were analyzed using SPSS version 16.0. The major roles identified by the unit managers were supervision (75.6%, n = 28) and coordination (70.3%, n = 26). Other roles such as team leader, liaison officer, research allocator, monitor and facilitator were rated by very few participants. Findings of the study showed that performance of unit nurse managers was affected by inadequate material (86.4%, n = 32) and human resources (94.5%, n = 35) and lack of managerial skills (5.4%, n = 2). In addition, the unit managers perceived their role to be stressful (38.9%, n = 14) and challenging (47.2%, n = 17). Therefore, there is a need to provide adequate material and human resources to the wards of the two central hospitals to enable the unit managers perform their duties efficiently.
基金Supported by Scientific research project of Heilongjiang Health and Family Planning Commission,No.2019045.
文摘BACKGROUND Ammonia is a normal constituent of body fluids and is found mainly through the formation of urea in the liver.Blood levels of ammonia must remain low as even slightly elevated concentrations(hyperammonemia)are toxic to the central nervous system.AIM To examine the relationship between the incidence of non-hepatic hyperammonemia(NHH)and the prognosis of patients who were admitted to the intensive care unit(ICU).METHODS This is a prospective,observational and single-center study.A total of 364 patients who were admitted to the ICU from November 2019 to February 2020 were initially enrolled.Changes in the levels of blood ammonia at the time of ICU admission and after ICU admission were continuously monitored.In addition,factors influencing the prognosis of NHH patients were analyzed.RESULTS A total of 204 patients who met the inclusion criteria were enrolled in this study,including 155 NHH patients and 44 severe-NHH patients.The incidence of NHH and severe-NHH was 75.98% and 21.57%,respectively.Patients with severe-NHH exhibited longer length of ICU stay and higher Acute Physiologic Assessment and Chronic Health Evaluation and Sequential Organ Failure Assessment scores compared to those with mild-NHH and non-NHH.Glasgow Coma Scale scores of patients with severe-NHH were than those of non-NHH patients.In addition,the mean and initial levels of ammonia in the blood might be helpful in predicting the prognosis of NHH.CONCLUSION High blood ammonia level is frequent among NHH patients admitted to the ICU,which is related to the clinical characteristics of patients.Furthermore,the level of blood ammonia may be helpful for prognosis prediction.
基金sponsored by the Natural Science Foundation of Xinjiang Uighur Autonomous Region2012211B56)the Natural Science Foundation of China(41374031)the Earthquake Science and Technology Spark Plan(XH1030),and the Earthquake Science and Technology Spark Progam XH14054Y)
文摘On the basis of the comparison data of Stage II of the tunnel site leveling project at Hutubi seismic station and the observation data of Stage IV of the site cross fault leveling project at Hutubi and the level observation data from the cross fault survey lines in Dafeng from 1987 to 2012,this paper analyses the variation rates of the tunnel site leveling observation results and the difference of annual change rates of the cross fault level observations at Hongshan seismic station in Hutubi. This paper concludes the reliability of the Ni004 optical level used by the station and puts forward a proposal based on the analysis. This paper also explores the cross fault leveling research on the ground deformation in the region concerned on the basis of the historical observation of the cross fault level at Dafeng and the comparison results of the tunnel site leveling observation in Hutubi.
文摘Current minimally invasive interventions for ureteric stones involve either ESWL or Ureteroscopy and stone localization is mandatory for successful treatment in both. Objectives: To avoid doing KUB radiograph before ESWL routinely by correlating the stone attenuation value on CT KUB with stone visualization at fluoroscopy. Methods: This is a prospective cross sectional hospital based, Multicentric study carried out on 1010 patients with ureteric stones in Sudan from August 2014 to March 2016. Results: Mean stone density in HU was 704.45 ± 300 (SD) ranging (81 - 1873) HU. All of the stones were localized using fluoroscopy and only 26.5% of them were not seen under fluoroscopy. I.V contrast was used mostly, and also mainly in the upper ureter. More than 80% of the application of contrast through the ureteric catheter was in the lower ureteric stones. 91.2% of patients with stone density ≤ 400 HU failed to appear at fluoroscopy and therefore 400 HU attenuation value can be used as a cut-off level to request doing KUB before ESWL and Ureteroscopy. Conclusion: the ureteric stones with density ≤400 HU the likelihood of being non-visualized at fluoroscopy is 91.2% therefore if the stone has ≤400 HU at CT KUB it is mandatory to do KUB before treatment above that it is most likely to be seen at fluoroscopy and no need to request KUB for them before ESWL or URS. 1) Inclusion Criteria: All patients diagnosed by CT scan to have ureteric stones for ESWL or Ureteroscopy. 2) Exclusion Criteria: Patients for whom treatment of ureteric stone by ESWL or ureteroscopy is not indicated like severe infection or poor kidney function where nephrectomy is needed.
文摘On July 9,the 2018 United Nations High Level Political Forum on Sustainable Development was grandly opened at the United Nations Headquarters in New York.China NGO Network for International Exchanges (CNIE)organized a number of social organizations in China to attend the forum,held a theme seminar,and participated in the photo exhibition of the forum.
基金Supported by National Nature Science Foundation of China(61472289)the Nature Science Foundation of Hubei Province(2015CFB254)
文摘In recent years, graphical processing unit (GPU)-accelerated intelligent algorithms have been widely utilized for solving combination optimization problems, which are NP-hard, These intelligent algorithms involves a common operation, namely reduction, in which the best suitable candidate solution in the neighborhood is selected. As one of the main procedures, it is necessary to optimize the reduction on the GPU. In this paper, we propose an enhanced warp-based reduction on the GPU. Compared with existing block-based reduction methods, our method exploit efficiently the potential of implementation at warp level, which better matches the characteristics of current GPU architecture. Firstly, in order to improve the global memory access performance, the vectoring accessing is utilized. Secondly, at the level of thread block reduction, an enhanced warp-based reduction on the shared memory are presented to form partial results. Thirdly, for the configuration of the number of thread blocks, the number of thread blocks can be obtained by maximizing the size of thread block and the maximum size of threads per stream multi-processor on GPU. Finally, the proposed method is evaluated on three generations of NVIDIA GPUs with the better performances than previous methods.
文摘为了进一步降低园区综合能源系统(park-level integrated energy system,PIES)碳排放量,优化热电联产(combined heat and power,CHP)机组出力的灵活性,提出一种考虑改进阶梯型碳交易和CHP热电灵活输出的PIES低碳经济调度策略。首先,将遗传算法与模糊控制相结合,设计一种遗传模糊碳交易参数优化器,从而对现有阶梯型碳交易机制进行改进,实现该机制参数的自适应变化;其次,在传统CHP中加入卡琳娜(Kalina)循环与电锅炉(electricboiler,EB),构造CHP热电灵活输出模型,以同时满足电、热负荷的不同需求;然后,提出一种柔性指标——电、热输出占比率,进而计算出电、热输出占比率区间,以衡量CHP运行灵活性;最后,将改进阶梯型碳交易机制和CHP热电灵活输出模型协同优化,以系统运行成本和碳交易成本之和最小为目标,构建PIES低碳经济优化模型。算例分析表明,所提策略可有效降低经济成本和碳排放量,同时还可扩展CHP灵活输出调节范围,能够为PIES低碳经济调度提供参考。