The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale,multifunctional,and complex orientations.The vibration caused by the high-frequency units during regular operation is ...The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale,multifunctional,and complex orientations.The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units,and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts,leading to variations in the dynamic response of the foundation.The high-frequency units yield significantly diverse outcomes under different startup conditions and times,resulting in failure to meet operational requirements,influencing the normal function of the tunnel,and causing harm to the foundation structure,personnel,and property in severe cases.This article formulates a finite element numerical computation model for solid elements using three-dimensional elastic body theory and integrates field measurements to substantiate and ascertain the crucial parameter configurations of the finite element model.By proposing a comprehensive startup timing function for high-frequency dynamic machines under different startup conditions,simulating the frequency andmagnitude variations during the startup process,and suggesting functions for changes in frequency and magnitude,a simulated startup schedule function for high-frequency machines is created through coupling.Taking into account the selection of the transient dynamic analysis step length,the dynamic response results for the lower dynamic foundation during its fundamental frequency crossing process are obtained.The validation checks if the structural magnitude surpasses the safety threshold during the critical phase of unit startup traversing the structural resonance region.The design recommendations for high-frequency units’dynamic foundations are provided,taking into account the startup process of the machine and ensuring the safe operation of the tunnel.展开更多
In this paper,we investigate sufficient and necessary conditions such that generalized Forelli-Rudin type operators T_(λ,τ,k),S_(λ,τ,k),Q_(λ,τ,k)and R_(λ,τ,k)are bounded between Lebesgue type spaces.In order t...In this paper,we investigate sufficient and necessary conditions such that generalized Forelli-Rudin type operators T_(λ,τ,k),S_(λ,τ,k),Q_(λ,τ,k)and R_(λ,τ,k)are bounded between Lebesgue type spaces.In order to prove the main results,we first give some bidirectional estimates for several typical integrals.展开更多
Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to spe...Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.展开更多
With the development of the technology of the Internet of Things,more and more operational data can be collected from air conditioning systems.Unfortunately,the most of existing air conditioning controllers mainly pro...With the development of the technology of the Internet of Things,more and more operational data can be collected from air conditioning systems.Unfortunately,the most of existing air conditioning controllers mainly provide controlling functions more than storing,processing or computing the measured data.This study develops an online fault detection configuration on the equipment side of air conditioning systems to realize these functions.Modbus communication is served to collect real-time operational data.The calculating programs are embedded to identify whether the measured signals exceed their limits or not,and to detect if sensor reading is frozen and other faults in relation to the operational performance are generated or not.The online fault detection configuration is tested on an actual variable-air-volume(VAV)air handling unit(AHU).The results show that the time ratio of fault detection exceeds 95.00%,which means that the configuration exhibits an acceptable fault detection effect.展开更多
Modular unit systems provide an eco-friendly advanced construction method that improves productivity and reduces carbon emissions and construction waste. In these systems, the prefabrication ratio of the modules shoul...Modular unit systems provide an eco-friendly advanced construction method that improves productivity and reduces carbon emissions and construction waste. In these systems, the prefabrication ratio of the modules should be high in order to support these eco-friendly features. The purpose of this study was to verify the functionality and driving safety of fixing a modular unit with a high prefabrication ratio to a vehicle for transportation to the site using two novel adapter blocks specially developed for this purpose. When asked to evaluate their performance for this study, the truck drivers selected adaptor block type B as providing the highest convenience and functionality. In real-world driving experiments, maximum loads of 15 kN and 25 kN were measured on adapter block types A and B, respectively. Future improvements in the adapter blocks that take the safety ratio and the improved convenience of use into account are confidently expected to contribute to the eco-friendliness and the improved productivity of modular unit systems.展开更多
In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of A...In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.展开更多
一、内容分析本课时为故事教学,讲述了Mocky与Ann,Ken相识的过程,自然呈现了用"Hello!"打招呼以及用"What’s your name?""My name is..."来询问和介绍姓名的表达法。本课的故事贴近学生生活,语言简单,...一、内容分析本课时为故事教学,讲述了Mocky与Ann,Ken相识的过程,自然呈现了用"Hello!"打招呼以及用"What’s your name?""My name is..."来询问和介绍姓名的表达法。本课的故事贴近学生生活,语言简单,便于学生理解。同时,介绍以姓名为主题的歌曲和问答活动,有利于学生的理解和巩固。在学习故事的过程中,认识故事主人公,记住他们的姓名Mocky、Ann、Ken也是本课时的重点。展开更多
In this article, the authors give a typical integral＇s bidirectional estimates for allcases. At the same time, several equivalent characterizations on the F（p, q, s, k） space in theunit ball of Cn are given.
This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to ...This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to Bers-type spaces Hv^∞（ or little Bers-type spaces Hv,o∞ ）, where v is normal.展开更多
基金Smart Integration Key Technologies and Application Demonstrations of Large Scale Underground Space Disaster Prevention and Reduction in Guangzhou International Financial City([2021]–KJ058).
文摘The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale,multifunctional,and complex orientations.The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units,and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts,leading to variations in the dynamic response of the foundation.The high-frequency units yield significantly diverse outcomes under different startup conditions and times,resulting in failure to meet operational requirements,influencing the normal function of the tunnel,and causing harm to the foundation structure,personnel,and property in severe cases.This article formulates a finite element numerical computation model for solid elements using three-dimensional elastic body theory and integrates field measurements to substantiate and ascertain the crucial parameter configurations of the finite element model.By proposing a comprehensive startup timing function for high-frequency dynamic machines under different startup conditions,simulating the frequency andmagnitude variations during the startup process,and suggesting functions for changes in frequency and magnitude,a simulated startup schedule function for high-frequency machines is created through coupling.Taking into account the selection of the transient dynamic analysis step length,the dynamic response results for the lower dynamic foundation during its fundamental frequency crossing process are obtained.The validation checks if the structural magnitude surpasses the safety threshold during the critical phase of unit startup traversing the structural resonance region.The design recommendations for high-frequency units’dynamic foundations are provided,taking into account the startup process of the machine and ensuring the safe operation of the tunnel.
基金supported by the Natural Science Foundation of Hunan Province of China(2022JJ30369)the Education Department Important Foundation of Hunan Province in China(23A0095)。
文摘In this paper,we investigate sufficient and necessary conditions such that generalized Forelli-Rudin type operators T_(λ,τ,k),S_(λ,τ,k),Q_(λ,τ,k)and R_(λ,τ,k)are bounded between Lebesgue type spaces.In order to prove the main results,we first give some bidirectional estimates for several typical integrals.
基金The authors thank the Yayasan Universiti Teknologi PETRONAS(YUTP FRG Grant No.015LC0-428)at Universiti Teknologi PETRO-NAS for supporting this study.
文摘Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.
基金Research Project of China Ship Development and Design Center,Wuhan,China。
文摘With the development of the technology of the Internet of Things,more and more operational data can be collected from air conditioning systems.Unfortunately,the most of existing air conditioning controllers mainly provide controlling functions more than storing,processing or computing the measured data.This study develops an online fault detection configuration on the equipment side of air conditioning systems to realize these functions.Modbus communication is served to collect real-time operational data.The calculating programs are embedded to identify whether the measured signals exceed their limits or not,and to detect if sensor reading is frozen and other faults in relation to the operational performance are generated or not.The online fault detection configuration is tested on an actual variable-air-volume(VAV)air handling unit(AHU).The results show that the time ratio of fault detection exceeds 95.00%,which means that the configuration exhibits an acceptable fault detection effect.
文摘Modular unit systems provide an eco-friendly advanced construction method that improves productivity and reduces carbon emissions and construction waste. In these systems, the prefabrication ratio of the modules should be high in order to support these eco-friendly features. The purpose of this study was to verify the functionality and driving safety of fixing a modular unit with a high prefabrication ratio to a vehicle for transportation to the site using two novel adapter blocks specially developed for this purpose. When asked to evaluate their performance for this study, the truck drivers selected adaptor block type B as providing the highest convenience and functionality. In real-world driving experiments, maximum loads of 15 kN and 25 kN were measured on adapter block types A and B, respectively. Future improvements in the adapter blocks that take the safety ratio and the improved convenience of use into account are confidently expected to contribute to the eco-friendliness and the improved productivity of modular unit systems.
基金supported by STI2030-Major Projects,No.2021ZD 0201801(to JG)Shanxi Province Basic Research Program,No.20210302123429(to QS).
文摘In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.
文摘一、内容分析本课时为故事教学,讲述了Mocky与Ann,Ken相识的过程,自然呈现了用"Hello!"打招呼以及用"What’s your name?""My name is..."来询问和介绍姓名的表达法。本课的故事贴近学生生活,语言简单,便于学生理解。同时,介绍以姓名为主题的歌曲和问答活动,有利于学生的理解和巩固。在学习故事的过程中,认识故事主人公,记住他们的姓名Mocky、Ann、Ken也是本课时的重点。
基金supported by the National Natural Science Foundation of China(11571104)the Hunan Provincial Innovation Foundation for Postgraduate(CX2017B220)Supported by the Construct Program of the Key Discipline in Hunan Province
文摘In this article, the authors give a typical integral＇s bidirectional estimates for allcases. At the same time, several equivalent characterizations on the F（p, q, s, k） space in theunit ball of Cn are given.
基金Supported by the National Natural Science Foundation of China (10771064)the Natural Science Foundation of Zhejiang province (Y6090036+1 种基金Y7080197,Y606197)the Foundation of Department of Education of Zhejiang Province (20070482)
文摘This paper deals with the boundedness and compactness of the weighted composition operators from the F（p, q, s） spaces, including Hardy space, Bergman space, Qp space, BMOA space, Besov space and α-Bloch space, to Bers-type spaces Hv^∞（ or little Bers-type spaces Hv,o∞ ）, where v is normal.
