Purpose: This study aims at identifying potential industry-university-research collaboration(IURC) partners effectively and analyzes the conditions and dynamics in the IURC process based on innovation chain theory....Purpose: This study aims at identifying potential industry-university-research collaboration(IURC) partners effectively and analyzes the conditions and dynamics in the IURC process based on innovation chain theory.Design/methodology/approach: The method utilizes multisource data, combining bibliometric and econometrics analyses to capture the core network of the existing collaboration networks and institution competitiveness in the innovation chain. Furthermore, a new identification method is constructed that takes into account the law of scientific research cooperation and economic factors.Findings: Empirical analysis of the genetic engineering vaccine field shows that through the distribution characteristics of creative technologies from different institutions, the analysis based on the innovation chain can identify the more complementary capacities among organizations.Research limitations: In this study, the overall approach is shaped by the theoretical concept of an innovation chain, a linear innovation model with specific types or stages of innovation activities in each phase of the chain, and may, thus, overlook important feedback mechanisms in the innovation process.Practical implications: Industry-university-research institution collaborations are extremely important in promoting the dissemination of innovative knowledge, enhancing the quality of innovation products, and facilitating the transformation of scientific achievements.Originality/value: Compared to previous studies, this study emulates the real conditions of IURC. Thus, the rule of technological innovation can be better revealed, the potential partners of IURC can be identified more readily, and the conclusion has more value.展开更多
To compare liver proteolysis and proteasome activation in steatotic liver grafts conserved in University of Wisconsin (UW) and Institut Georges Lopez-1 (IGL-1) solutions.METHODSFatty liver grafts from male obese Z...To compare liver proteolysis and proteasome activation in steatotic liver grafts conserved in University of Wisconsin (UW) and Institut Georges Lopez-1 (IGL-1) solutions.METHODSFatty liver grafts from male obese Zücker rats were conserved in UW and IGL-1 solutions for 24 h at 4 °Cand subjected to “ex vivo” normo-thermic perfusion (2 h; 37 °C). Liver proteolysis in tissue specimens and perfusate was measured by reverse-phase high performance liquid chromatography. Total free amino acid release was correlated with the activation of the ubiquitin proteasome system (UPS: measured as chymotryptic-like activity and 20S and 19S proteasome), the prevention of liver injury (transaminases), mitochondrial injury (confocal microscopy) and inflammation markers (TNF 1 alpha, high mobility group box-1 (HGMB-1) and PPAR gamma), and liver apoptosis (TUNEL assay, cytochrome c and caspase 3).RESULTSProfiles of free AA (alanine, proline, leucine, isoleucine, methionine, lysine, ornithine, and threonine, among others) were similar for tissue and reperfusion effluent. In all cases, the IGL-1 solution showed a significantly higher prevention of proteolysis than UW (P < 0.05) after cold ischemia reperfusion. Livers conserved in IGL-1 presented more effective prevention of ATP-breakdown and more inhibition of UPS activity (measured as chymotryptic-like activity). In addition, the prevention of liver proteolysis and UPS activation correlated with the prevention of liver injury (AST/ALT) and mitochondrial damage (revealed by confocal microscopy findings) as well as with the prevention of inflammatory markers (TNF1alpha and HMGB) after reperfusion. In addition, the liver grafts preserved in IGL-1 showed a significant decrease in liver apoptosis, as shown by TUNEL assay and the reduction of cytochrome c, caspase 3 and P62 levels.CONCLUSIONOur comparison of these two preservation solutions suggests that IGL-1 helps to prevent ATP breakdown more effectively than UW and subsequently achieves a higher UPS inhibition and reduced liver proteolysis.展开更多
In 1978, Professor Songshou Jin, a Chinese prestigious physical chemist, established Institute of Catalysis, Hangzhou University, the forerunner of Institute of Catalysis, Zhejiang University. In 1998, the current Ins...In 1978, Professor Songshou Jin, a Chinese prestigious physical chemist, established Institute of Catalysis, Hangzhou University, the forerunner of Institute of Catalysis, Zhejiang University. In 1998, the current Institute of Catalysis was re-established through the merger of Zhejiang University and Hangzhou University et al. During the past forty years, researchers in Institute of Catalysis had always paid much attention to the combination of fundamental researches and industrial applications under the lead of Songshou Jin, Xiaoming Zheng, Weimin Lu, Hui Lou, and Yong Wang. The major research interest includes:(1) basic application research and exploitation of catalysts and catalytic process regarding conversion of biomass, methane, syngas and carbon dioxide;(2) development of catalysts and reaction apparatus for industrial hazardous gas, indoor gas, vehicle emissions and oil smoke from hotels and restaurants;(3) synthesis, characterization of functional materials and their applications in the green synthesis in fields of medicine, pesticide and fine chemical;(4) heterogeneous and homogeneous catalytic reaction kinetics and surface chemistry;(5) catalytic researches regarding military project.展开更多
We now hold 200 classes in the Sheffield Confucius Institute,and 14,000 local residents have studied in it.Besides the cooperation with Chinese universities to offer language courses,our focus is to deepen mutual unde...We now hold 200 classes in the Sheffield Confucius Institute,and 14,000 local residents have studied in it.Besides the cooperation with Chinese universities to offer language courses,our focus is to deepen mutual understanding between the two nations’business partners.展开更多
The Institute of Materials Science atJilin University(IMSJU),located inChangchun,north east of China,is a majorresearch center in Jilin University which isone of the key universities in China.Its mainactivity is resea...The Institute of Materials Science atJilin University(IMSJU),located inChangchun,north east of China,is a majorresearch center in Jilin University which isone of the key universities in China.Its mainactivity is research and development in thefield of materials science and technology,especially concerning the advanced展开更多
The Population Research Institute of Tibet University was estab lished in October 1995.It is presently affiliated to.the Geography Department and headed by Mr.Niu Zhifu Vice President of the university a and Mme.Chen ...The Population Research Institute of Tibet University was estab lished in October 1995.It is presently affiliated to.the Geography Department and headed by Mr.Niu Zhifu Vice President of the university a and Mme.Chen Hua.There are six research staff members,halfof them are part time re-searchers.Key researchers are Mme.Chen Hua,Suolang Renqing and Luo Za.The institute's present tasks are regu lar,teaching on popu lation and demographic research.展开更多
Tbe Poulation Ro arh Iste was esbhediah May 1979,with。esce staf of 12,incuding thee po-consists of four of cesspeialing in population theory,Rplin ad the eompoulot and popilation inforination.
Tianjin Medical University Cancer Institute and Hospital (TMUCIH) is the birthplace of Oncology in China. It has a history of more than a hundred years and has become one of the most famous modernized cancer hospitals...Tianjin Medical University Cancer Institute and Hospital (TMUCIH) is the birthplace of Oncology in China. It has a history of more than a hundred years and has become one of the most famous modernized cancer hospitals worldwide. It is also one of the largest bases for cancer prevention, treatment, training and research in China.展开更多
The waste referred to includes solid waste and sludge. Solid waste is mainly from urban garbage and industrial waste. Sludge is from water treatment factories, paper mills, chemical factories, pharmaceutical factories...The waste referred to includes solid waste and sludge. Solid waste is mainly from urban garbage and industrial waste. Sludge is from water treatment factories, paper mills, chemical factories, pharmaceutical factories, rivers and lakes. The waste and sludge are very harmful to water organisms, human health and drinking water, and directly affect the environment. Sludge and waste also occupy large areas of land. There are several methods to treat waste and sludge, such as burial, chemical treatment and incineration. Incineration is more effective than the展开更多
Assyriology QI Xiao, MA The Reconstruction of the Archive of Ur-Kununna, the Scribe of Animal Center of Ur-III Dynasty (ulgi 43 ii - Ibbi-Sin 2 iv) (Supervisor: Wu Yuhong)
Ma Xiaoying, Assyriology, Ph.D., 1994.12 "Women’s Social Status in Old Babylonia Reflected in Marital Property" (Supervisors: Professors Lin Zhichun, Thomas Lee, Tova Meltzer, Wu Yuhong) Wang Liying, Cla...Ma Xiaoying, Assyriology, Ph.D., 1994.12 "Women’s Social Status in Old Babylonia Reflected in Marital Property" (Supervisors: Professors Lin Zhichun, Thomas Lee, Tova Meltzer, Wu Yuhong) Wang Liying, Classics, Ph.D., 1995.6 "Sallust’s Bellum Catilinae" (Supervisors: Porfessors Wang Dunshu, P.Ruth Taylor-Briggs, F. Ahlheid, Lin Zhichun)展开更多
基金funded by National Natural Science Foundation of China (Grant No. 71704170)the China Postdoctoral Science Foundation funded project (Grant No. 2016M590124)the Youth Innovation Promotion Association, CAS (Grant No. 2016159)
文摘Purpose: This study aims at identifying potential industry-university-research collaboration(IURC) partners effectively and analyzes the conditions and dynamics in the IURC process based on innovation chain theory.Design/methodology/approach: The method utilizes multisource data, combining bibliometric and econometrics analyses to capture the core network of the existing collaboration networks and institution competitiveness in the innovation chain. Furthermore, a new identification method is constructed that takes into account the law of scientific research cooperation and economic factors.Findings: Empirical analysis of the genetic engineering vaccine field shows that through the distribution characteristics of creative technologies from different institutions, the analysis based on the innovation chain can identify the more complementary capacities among organizations.Research limitations: In this study, the overall approach is shaped by the theoretical concept of an innovation chain, a linear innovation model with specific types or stages of innovation activities in each phase of the chain, and may, thus, overlook important feedback mechanisms in the innovation process.Practical implications: Industry-university-research institution collaborations are extremely important in promoting the dissemination of innovative knowledge, enhancing the quality of innovation products, and facilitating the transformation of scientific achievements.Originality/value: Compared to previous studies, this study emulates the real conditions of IURC. Thus, the rule of technological innovation can be better revealed, the potential partners of IURC can be identified more readily, and the conclusion has more value.
基金Supported by Instituto de Salud Carlos III(ISCIII)through the FIS project PI12/0056,co-funded by FEDER from Regional Development European Funds(European Union)
文摘To compare liver proteolysis and proteasome activation in steatotic liver grafts conserved in University of Wisconsin (UW) and Institut Georges Lopez-1 (IGL-1) solutions.METHODSFatty liver grafts from male obese Zücker rats were conserved in UW and IGL-1 solutions for 24 h at 4 °Cand subjected to “ex vivo” normo-thermic perfusion (2 h; 37 °C). Liver proteolysis in tissue specimens and perfusate was measured by reverse-phase high performance liquid chromatography. Total free amino acid release was correlated with the activation of the ubiquitin proteasome system (UPS: measured as chymotryptic-like activity and 20S and 19S proteasome), the prevention of liver injury (transaminases), mitochondrial injury (confocal microscopy) and inflammation markers (TNF 1 alpha, high mobility group box-1 (HGMB-1) and PPAR gamma), and liver apoptosis (TUNEL assay, cytochrome c and caspase 3).RESULTSProfiles of free AA (alanine, proline, leucine, isoleucine, methionine, lysine, ornithine, and threonine, among others) were similar for tissue and reperfusion effluent. In all cases, the IGL-1 solution showed a significantly higher prevention of proteolysis than UW (P < 0.05) after cold ischemia reperfusion. Livers conserved in IGL-1 presented more effective prevention of ATP-breakdown and more inhibition of UPS activity (measured as chymotryptic-like activity). In addition, the prevention of liver proteolysis and UPS activation correlated with the prevention of liver injury (AST/ALT) and mitochondrial damage (revealed by confocal microscopy findings) as well as with the prevention of inflammatory markers (TNF1alpha and HMGB) after reperfusion. In addition, the liver grafts preserved in IGL-1 showed a significant decrease in liver apoptosis, as shown by TUNEL assay and the reduction of cytochrome c, caspase 3 and P62 levels.CONCLUSIONOur comparison of these two preservation solutions suggests that IGL-1 helps to prevent ATP breakdown more effectively than UW and subsequently achieves a higher UPS inhibition and reduced liver proteolysis.
文摘In 1978, Professor Songshou Jin, a Chinese prestigious physical chemist, established Institute of Catalysis, Hangzhou University, the forerunner of Institute of Catalysis, Zhejiang University. In 1998, the current Institute of Catalysis was re-established through the merger of Zhejiang University and Hangzhou University et al. During the past forty years, researchers in Institute of Catalysis had always paid much attention to the combination of fundamental researches and industrial applications under the lead of Songshou Jin, Xiaoming Zheng, Weimin Lu, Hui Lou, and Yong Wang. The major research interest includes:(1) basic application research and exploitation of catalysts and catalytic process regarding conversion of biomass, methane, syngas and carbon dioxide;(2) development of catalysts and reaction apparatus for industrial hazardous gas, indoor gas, vehicle emissions and oil smoke from hotels and restaurants;(3) synthesis, characterization of functional materials and their applications in the green synthesis in fields of medicine, pesticide and fine chemical;(4) heterogeneous and homogeneous catalytic reaction kinetics and surface chemistry;(5) catalytic researches regarding military project.
文摘We now hold 200 classes in the Sheffield Confucius Institute,and 14,000 local residents have studied in it.Besides the cooperation with Chinese universities to offer language courses,our focus is to deepen mutual understanding between the two nations’business partners.
文摘The Institute of Materials Science atJilin University(IMSJU),located inChangchun,north east of China,is a majorresearch center in Jilin University which isone of the key universities in China.Its mainactivity is research and development in thefield of materials science and technology,especially concerning the advanced
文摘The Population Research Institute of Tibet University was estab lished in October 1995.It is presently affiliated to.the Geography Department and headed by Mr.Niu Zhifu Vice President of the university a and Mme.Chen Hua.There are six research staff members,halfof them are part time re-searchers.Key researchers are Mme.Chen Hua,Suolang Renqing and Luo Za.The institute's present tasks are regu lar,teaching on popu lation and demographic research.
文摘Tbe Poulation Ro arh Iste was esbhediah May 1979,with。esce staf of 12,incuding thee po-consists of four of cesspeialing in population theory,Rplin ad the eompoulot and popilation inforination.
文摘Tianjin Medical University Cancer Institute and Hospital (TMUCIH) is the birthplace of Oncology in China. It has a history of more than a hundred years and has become one of the most famous modernized cancer hospitals worldwide. It is also one of the largest bases for cancer prevention, treatment, training and research in China.
文摘The waste referred to includes solid waste and sludge. Solid waste is mainly from urban garbage and industrial waste. Sludge is from water treatment factories, paper mills, chemical factories, pharmaceutical factories, rivers and lakes. The waste and sludge are very harmful to water organisms, human health and drinking water, and directly affect the environment. Sludge and waste also occupy large areas of land. There are several methods to treat waste and sludge, such as burial, chemical treatment and incineration. Incineration is more effective than the
文摘Assyriology QI Xiao, MA The Reconstruction of the Archive of Ur-Kununna, the Scribe of Animal Center of Ur-III Dynasty (ulgi 43 ii - Ibbi-Sin 2 iv) (Supervisor: Wu Yuhong)
文摘Ma Xiaoying, Assyriology, Ph.D., 1994.12 "Women’s Social Status in Old Babylonia Reflected in Marital Property" (Supervisors: Professors Lin Zhichun, Thomas Lee, Tova Meltzer, Wu Yuhong) Wang Liying, Classics, Ph.D., 1995.6 "Sallust’s Bellum Catilinae" (Supervisors: Porfessors Wang Dunshu, P.Ruth Taylor-Briggs, F. Ahlheid, Lin Zhichun)