In recent times,wireless sensor network(WSN)finds their suitability in several application areas,ranging from military to commercial ones.Since nodes in WSN are placed arbitrarily in the target field,node localization...In recent times,wireless sensor network(WSN)finds their suitability in several application areas,ranging from military to commercial ones.Since nodes in WSN are placed arbitrarily in the target field,node localization(NL)becomes essential where the positioning of the nodes can be determined by the aid of anchor nodes.The goal of any NL scheme is to improve the localization accuracy and reduce the localization error rate.With this motivation,this study focuses on the design of Intelligent Aquila Optimization Algorithm Based Node Localization Scheme(IAOAB-NLS)for WSN.The presented IAOAB-NLS model makes use of anchor nodes to determine proper positioning of the nodes.In addition,the IAOAB-NLS model is stimulated by the behaviour of Aquila.The IAOAB-NLS model has the ability to accomplish proper coordinate points of the nodes in the network.For guaranteeing the proficient NL process of the IAOAB-NLS model,widespread experimentation takes place to assure the betterment of the IAOAB-NLS model.The resultant values reported the effectual outcome of the IAOAB-NLS model irrespective of changing parameters in the network.展开更多
The management of cervical lymph node metastases of squamous cell carcinoma from an unknown primary site is still a therapeutic challenge.We report here our experience in treating these patients with chemoradiotherapy...The management of cervical lymph node metastases of squamous cell carcinoma from an unknown primary site is still a therapeutic challenge.We report here our experience in treating these patients with chemoradiotherapy as a curative approach.Data from 40 patients were reviewed.In total,20(50%) patients underwent excisional biopsy.All patients underwent radiotherapy,which was delivered to both sides of the neck and pharyngeal mucosa(extensive field),and concurrent chemotherapy consisting of weekly cisplatin at a dose of 40 mg/m2.The clinical stage of the cervical nodes at presentation was N1 in 25%,N2 in 60%,and N3 in 15%.Most patients(75%) developed at least grade 3 mucositis.Eight patients(20%) had grade 3 xerostomia and 18 patients(45%) required esophageal dilation for stricture.The 5-year overall survival(OS) rate of all patients was 67.5%.The 5-year OS rates of patients with N1,N2,and N3 lesions were 100%,67%,and 41%,respectively(P = 0.046).The 5-year progression-free survival rate was 62.5%.In multivariate analysis,only N stage significantly affected OS(P = 0.022).Emergence of the occult primary was very limited(1 patient only).Our results suggest that extensive irradiation of both sides of the neck and pharyngeal mucosa with concurrent chemotherapy results in a lower emergence of primary tumor.Because the survival of patients with unknown primary is comparable to that of patients with known primary,an attempt at cure should always be made.展开更多
Carcinoma of unknown primary (CUP) is occasionally encountered in clinical oncology. Wide variation exists in CUP. We herein report a rare case of CUP of a mediastinal lymph node. A 61-year-old man with dermatomyositi...Carcinoma of unknown primary (CUP) is occasionally encountered in clinical oncology. Wide variation exists in CUP. We herein report a rare case of CUP of a mediastinal lymph node. A 61-year-old man with dermatomyositis was referred to our hospital for treatment of mediastinal adenopathy and gastric cancer. Biopsy of both lesions showed that they were histologically different from each other. Mediastinal lymphadenectomy and total gastrectomy were performed for a definitive diagnosis and radical cure. Pathological examination revealed two distinctly different disease processes. The patient underwent postoperative chemotherapy for residual gastric cancer. Twenty months postoperatively, he is alive with cancer. Although CUP usually has a poor prognosis, surgical treatment of metastatic mediastinal lymph node CUP is a feasible therapeutic option.展开更多
基金The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work underGrant Number(RGP 1/322/42)PrincessNourah bint Abdulrahman UniversityResearchers Supporting Project number(PNURSP2022R303)Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘In recent times,wireless sensor network(WSN)finds their suitability in several application areas,ranging from military to commercial ones.Since nodes in WSN are placed arbitrarily in the target field,node localization(NL)becomes essential where the positioning of the nodes can be determined by the aid of anchor nodes.The goal of any NL scheme is to improve the localization accuracy and reduce the localization error rate.With this motivation,this study focuses on the design of Intelligent Aquila Optimization Algorithm Based Node Localization Scheme(IAOAB-NLS)for WSN.The presented IAOAB-NLS model makes use of anchor nodes to determine proper positioning of the nodes.In addition,the IAOAB-NLS model is stimulated by the behaviour of Aquila.The IAOAB-NLS model has the ability to accomplish proper coordinate points of the nodes in the network.For guaranteeing the proficient NL process of the IAOAB-NLS model,widespread experimentation takes place to assure the betterment of the IAOAB-NLS model.The resultant values reported the effectual outcome of the IAOAB-NLS model irrespective of changing parameters in the network.
文摘The management of cervical lymph node metastases of squamous cell carcinoma from an unknown primary site is still a therapeutic challenge.We report here our experience in treating these patients with chemoradiotherapy as a curative approach.Data from 40 patients were reviewed.In total,20(50%) patients underwent excisional biopsy.All patients underwent radiotherapy,which was delivered to both sides of the neck and pharyngeal mucosa(extensive field),and concurrent chemotherapy consisting of weekly cisplatin at a dose of 40 mg/m2.The clinical stage of the cervical nodes at presentation was N1 in 25%,N2 in 60%,and N3 in 15%.Most patients(75%) developed at least grade 3 mucositis.Eight patients(20%) had grade 3 xerostomia and 18 patients(45%) required esophageal dilation for stricture.The 5-year overall survival(OS) rate of all patients was 67.5%.The 5-year OS rates of patients with N1,N2,and N3 lesions were 100%,67%,and 41%,respectively(P = 0.046).The 5-year progression-free survival rate was 62.5%.In multivariate analysis,only N stage significantly affected OS(P = 0.022).Emergence of the occult primary was very limited(1 patient only).Our results suggest that extensive irradiation of both sides of the neck and pharyngeal mucosa with concurrent chemotherapy results in a lower emergence of primary tumor.Because the survival of patients with unknown primary is comparable to that of patients with known primary,an attempt at cure should always be made.
文摘Carcinoma of unknown primary (CUP) is occasionally encountered in clinical oncology. Wide variation exists in CUP. We herein report a rare case of CUP of a mediastinal lymph node. A 61-year-old man with dermatomyositis was referred to our hospital for treatment of mediastinal adenopathy and gastric cancer. Biopsy of both lesions showed that they were histologically different from each other. Mediastinal lymphadenectomy and total gastrectomy were performed for a definitive diagnosis and radical cure. Pathological examination revealed two distinctly different disease processes. The patient underwent postoperative chemotherapy for residual gastric cancer. Twenty months postoperatively, he is alive with cancer. Although CUP usually has a poor prognosis, surgical treatment of metastatic mediastinal lymph node CUP is a feasible therapeutic option.
