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Percutaneous kyphoplasty in the treatment of Kümmell disease in lumbar scoliosis:A case report
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作者 Saijilafu Jia-Wen Zhou +2 位作者 Gen-Lin Wang Ke-Hong Sun Ji-Le Xie 《World Journal of Clinical Cases》 SCIE 2024年第17期3123-3129,共7页
BACKGROUND Due to mechanical imbalance in the spine,elderly scoliosis patients tend to develop vertebral fracture nonunion,i.e.,Kümmell disease,when osteoporotic vertebral compression fractures occur.However,acco... BACKGROUND Due to mechanical imbalance in the spine,elderly scoliosis patients tend to develop vertebral fracture nonunion,i.e.,Kümmell disease,when osteoporotic vertebral compression fractures occur.However,accompanying vertebral rotational deformities make surgical procedures challenging risky.Such patients are usually compelled to undergo conservative treatment and there are very few reports on minimally invasive surgeries for them.We first-time report a patient with Kümmell disease and lumbar scoliosis treated with percutaneous kyphoplasty(PKP)under O-arm guidance.CASE SUMMARY An 89-year-old female was admitted to the hospital due to delayed low back pain after a fall.She was diagnosed with Kümmell disease based on physical and radiologic examinations.The patient experienced severe scoliosis and subsequently underwent O-arm-guided kyphoplasty,resulting in a significant alleviation of low back pain.CONCLUSION PKP has good efficacy in treating Kümmell disease.However,surgical risks are elevated in scoliosis patients with Kümmell disease due to the abnormal anatomical structure of the spine.O-arm assisted operations play a crucial role in decreasing surgical risks. 展开更多
关键词 kümmell disease Vertebral compression fracture SCOLIOSIS kYPHOPLASTY Case report
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Treatment of Kümmell’s disease with sequential infusion of bone cement:A retrospective study 被引量:6
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作者 Xing Zhang Yong-Chao Li +2 位作者 Hong-Peng Liu Bing Zhou Hui-Lin Yang 《World Journal of Clinical Cases》 SCIE 2020年第23期5887-5893,共7页
BACKGROUND Percutaneous vertebroplasty(PVP)is an effective method for the treatment of neurologically intact Kümmell’s disease,but bone cement leakage during surgery is a problem that deserves attention.AIM To r... BACKGROUND Percutaneous vertebroplasty(PVP)is an effective method for the treatment of neurologically intact Kümmell’s disease,but bone cement leakage during surgery is a problem that deserves attention.AIM To reduce bone cement leakage and evaluate the effect of the sequential infusion of bone cement during PVP for the treatment of stage I or II Kümmell’s disease.METHODS Patients with Kümmell’s disease treated in our hospital from September 2015 to September 2018 were retrospectively analyzed.Patients meeting the inclusion and exclusion criteria were divided into two groups:Traditional single infusion and sequential infusion(SI).The visual analog scale(VAS)and Oswestry disability index(ODI)were evaluated and compared,and duration of operation,bone cement content and complications were recorded.RESULTS Forty-five patients were included in this study;there were 24 in the traditional single infusion group and 21 in the SI group.The VAS and ODI were significantly different for both groups when compared pre-and postoperatively,whereas the differences between 1 wk postoperatively and at the final follow-up were not statistically.When the VAS and ODI of the two groups were compared,there were no significant differences at any time point.The leakage rate of bone cement was significantly lower in the SI group(14.3%,3 of 21)than that in the traditional single infusion group(41.7%,10 of 24).CONCLUSION SI in unipedicular PVP is a safe and effective procedure for neurologically intact Kümmell’s disease,and this technique could decrease the incidence of bone cement leakage. 展开更多
关键词 kümmell’s disease Percutaneous vertebroplasty Bone cement leakage Back pain OSTEOPOROSIS Intravertebral vacuum cleft
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Percutaneous vertebroplasty versus percutaneous kyphoplasty for the treatment of delayed post-traumatic vertebral body collapse(Kümmell’s disease) in Chinese patients: a systematic review and meta-analysis 被引量:1
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作者 Peng-Fei Han Cheng-Long Chen +4 位作者 Tao-Yu Chen Zhi-Liang Zhang Xiao-Dong Li Peng-Cui Li Xiao-Chun Wei 《Frontiers of Nursing》 CAS 2019年第4期273-283,共11页
Objective: To compare the clinical efficacy between percutaneous vertebroplasty(PVP) and percutaneous kyphoplasty(PKP) in the treatment of Kümmell's disease in Chinese patients.Methods: The studies using rand... Objective: To compare the clinical efficacy between percutaneous vertebroplasty(PVP) and percutaneous kyphoplasty(PKP) in the treatment of Kümmell's disease in Chinese patients.Methods: The studies using randomized controlled trials to compare clinical efficacy between PVP and PKP in the treatment of Kümmell's disease in Chinese patients were retrieved from Embase, Pubmed, Central, Cinahl, PQDT, CNKI, CQVIP, Wanfang Data, and CBM(from September 2008 to September 2018). Keywords for both Chinese and English search were: percutaneous vertebroplasty, PVP, percutaneous kyphoplasty, PKP, and Kümmell's disease. A total of 132 articles were retrieved based on the search strategy through online database searching and manual searching. Finally, one foreign report and seven Chinese reports were included. After extracting the data, statistical software Review Manager 5.3 was used for data analysis.Results: Through comparison, Cobb angle(95% CI [0.54, 4.42), P = 0.01] and Oswestry Dysfunction Index(ODI)(95% CI [0.21, 2.15], P= 0.02) of PKP group was smaller than that of PVP group. Postoperative anterior vertebral body height of the PKP group was better than PVP group(95% CI [-1.27,-0.66], P < 0.001]. However, the PVP group had shorter operation time than PKP group(95% CI [-13.48,-7.43), P = 0.001]. In the other outcome measures, including Visual Analogue Scale(VAS) score(95% CI [-0.04, 0.27), P = 0.15), cement volume(95% CI [-0.82, 0.32], P = 0.39) and cement leakage(95% CI [0.90, 2.76], P = 0.11), there was no significant differences between the two procedures.Conclusions: At this stage, there is sufficient evidence to support that PKP is better than PVP in the treatment of Kümmell's disease in Chinese patients. Although PVP surgery requires much less operation time, PKP has better postoperative radiological results and lower ODI. Moreover, both of them had similar clinical results(e.g., analgesic effects, cement dosage, and leakage rate). Further evidence is dependent on the emergence of randomized controlled trials with higher quality and larger sample sizes in the future. 展开更多
关键词 kümmell’s disease percutaneous vertebroplasty percutaneous kyphoplasty post-trauma vertebral body collapse META-ANALYSIS systematic review
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椎体后凸成形术治疗无神经症状Kümmell病的疗效观察 被引量:1
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作者 柳扬 包呼日查 +9 位作者 孙永青 范磊 郝敬东 崔准 张怀华 康建国 任磊 邓超 赵大中 蒋育欣 《中国骨与关节外科》 2013年第6期477-481,共5页
背景:目前,Kümmell病相关文献报道较少,诊断和治疗仍存争议,对于此病的认识有待进一步加深。目的目的:深化对Kümmell病的认识并探讨椎体后凸成形术治疗无神经症状Kümmell病的短期疗效。方法方法:2007年2月至2012年3月,1... 背景:目前,Kümmell病相关文献报道较少,诊断和治疗仍存争议,对于此病的认识有待进一步加深。目的目的:深化对Kümmell病的认识并探讨椎体后凸成形术治疗无神经症状Kümmell病的短期疗效。方法方法:2007年2月至2012年3月,13例无神经症状Kümmell病患者接受球囊扩张椎体后凸成形术。分别于术前、术后记录Oswestry功能障碍指数(ODI)、疼痛视觉模拟评分(VAS)、伤椎和邻椎高度、受累节段矢状面Cobb角,认为VAS减少50%为疼痛明显缓解,ODI减少50%为功能明显改善。结果结果:患者术后3 d,1个月、3个月、12个月VAS平均评分分别为6.7±0.88、4.3±0.64、3.6±0.69和3.2±0.90,与术前比较均有显著统计学差异(P<0.05),末次随访时疼痛缓解率为81%。12例患者的运动功能有明显改善;术后3 d,1个月、3个月、12个月ODI平均评分分别为23.5±1.90、15.0±0.86、13.8±0.60和12.5±0.50,与术前比较均有显著统计学差异(P<0.05),末次随访时运动功能改善率为71%。术后伤椎高度较术前明显增加,术后12个月时伤椎高度平均为(18.5±1.59)cm,与术前比较有显著统计学差异(P<0.05)。但术后随访时各时间点邻椎高度较术前无明显改变(P>0.05)。术后伤椎节段Cobb角较术前明显减小,术后12个月时伤椎节段Cobb角平均为14.6°±1.46°,与术前比较有显著统计学差异(P<0.05)。结论结论:目前对于Kümmell病的认识仍存不全面;椎体后凸成形术是治疗无神经症状Kümmell病有效方法之一。 展开更多
关键词 kummell 椎体后凸成术
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血清组织蛋白酶K、胱抑素C水平与缺血性脑血管病患者颈动脉粥样硬化斑块稳定性的关系 被引量:14
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作者 郭夏青 卢宏 《郑州大学学报(医学版)》 CAS 北大核心 2013年第2期269-271,共3页
目的:探讨血清组织蛋白酶K(CatK)和胱抑素C(CysC)水平与超声评价的缺血性脑血管病患者颈动脉粥样硬化斑块稳定性的关系。方法:167例缺血性脑血管病患者根据颈动脉超声检查结果分为无斑块组53例、稳定斑块组53例和不稳定斑块组61例,采用E... 目的:探讨血清组织蛋白酶K(CatK)和胱抑素C(CysC)水平与超声评价的缺血性脑血管病患者颈动脉粥样硬化斑块稳定性的关系。方法:167例缺血性脑血管病患者根据颈动脉超声检查结果分为无斑块组53例、稳定斑块组53例和不稳定斑块组61例,采用ELISA法测定3组患者血清CatK、CysC水平。结果:3组血清CatK和CysC水平差异有统计学意义(F=7.539和2.733,P均<0.05)。与稳定斑块组及无斑块组比较,不稳定斑块组血清CatK水平较高,而CysC水平较低(P<0.05)。非条件logistic回归分析结果显示,在多因素校正后,CatK仍为颈动脉不稳定的危险因素(OR=1.229,95%CI=1.089~1.388),CysC为保护性因素(OR=0.995,95%CI=0.991~0.999)。结论:组织蛋白酶CatK及其内源性抑制剂CysC表达失衡可能是缺血性脑血管病患者颈动脉粥样硬化斑块不稳定的机制之一。 展开更多
关键词 缺血性脑血管病 颈动脉粥样硬化 不稳定斑块 组织蛋白酶k 胱抑素C
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