Objective To examine the relationship between upper leg length （ULL） and metabolic syndrome （MetS） in older adults.Methods Data was collected from National Health and Nutritional Examination Survey （NHANES, 2009-...Objective To examine the relationship between upper leg length （ULL） and metabolic syndrome （MetS） in older adults.Methods Data was collected from National Health and Nutritional Examination Survey （NHANES, 2009-2010）. 786 individuals （385 males and 401 females） who were 60 years of age or older were included in this analysis. MetS was defined as having at least three of following conditions, i.e., cen-tral obesity, dyslipidemia, insulin resistance, and hypertension based on National Cholesterol Education Program guidelines. ULL was grouped into gender-specific tertiles.Results328 （41.7%） of participants were categorized as having MetS （38.7% in men and 49.1% in women,P = 0.002）. Compared to individuals in the 1st tertile （T1） of ULL, those in the 3rd tertile （T3） had lower levels of triglycerides （120.8 vs. 153.1 mg/dL,P = 0.045）, waist circumference （100.7vs. 104.2 cm,P = 0.049）, and systolic blood pressure （126.7vs. 131.4 mmHg, P = 0.005）, but higher levels of high-density-lipoprotein cholesterol （58.1vs. 52.4 mg/dL,P = 0.024）. The odds ratios （95% CI） of MetS from multivariate logistic regression were 0.57 （0.32-1.03） for individuals in the T2 of ULL and 0.39 （0.24-0.64） for individuals in the T3 of ULL, respectively （P-value for the trend 0.022）.Conclusions ULL was negatively associated with MetS in older adults. Further research is needed to identify potential mechanisms.展开更多
针对汽车行人保护碰撞试验中大腿冲击器的生物力学特性问题,采用THUMS(total human model for safety)人体模型与大腿冲击器进行对比仿真分析.模拟THUMS-SUV行人交通事故,并对THUMS人体模型大腿所受冲击力和弯矩进行了输出.根据事故中...针对汽车行人保护碰撞试验中大腿冲击器的生物力学特性问题,采用THUMS(total human model for safety)人体模型与大腿冲击器进行对比仿真分析.模拟THUMS-SUV行人交通事故,并对THUMS人体模型大腿所受冲击力和弯矩进行了输出.根据事故中行人大腿初始碰撞条件和行人大腿最低能量状态,分别建立两种工况的行人大腿冲击器碰撞模型并进行模拟,对比分析行人大腿冲击器和THUMS人体模型大腿的动态响应、最大瞬间冲击力和最大弯矩.仿真结果表明:相对THUMS人体模型而言,大腿冲击器的最大瞬间冲击力偏高而最大弯矩偏低,行人小腿和上身的运动和接触作用,会影响大腿部位的接触力和最大弯矩,因此大腿冲击器的生物仿真度有待提高.展开更多
目的探讨被动抬腿试验联合上肢抬高(PLR combined with upper limb elevation,uPLR)是否提高预测感染性休克病患者容量反应性的准确性。方法2014年10月-2017年10月入住徐州市第一医院重症医学科19例感染性休克患者纳入研究。采用脉搏指...目的探讨被动抬腿试验联合上肢抬高(PLR combined with upper limb elevation,uPLR)是否提高预测感染性休克病患者容量反应性的准确性。方法2014年10月-2017年10月入住徐州市第一医院重症医学科19例感染性休克患者纳入研究。采用脉搏指示连续心输出量及呼气二氧化碳监测技术监测被动抬腿试验(Passive leg raising,PLR)、uPLR和液体负荷试验前后患者每搏量(Stroke volume,SV)、脉压(pulse pressure,PP)、呼气二氧化碳容积(carbon dioxide of elimination of per breath,VTCO2br)和呼气末二氧化碳分压(end tidal carbon dioxide partial pressure,PETCO2)的变化情况,容量负荷试验后SV增加值(△SV)≥10%定义为容量反应阳性。采用ROC曲线分析PLR和uPLR预测容量反应性的准确性。结果19例患者行53次容量负荷试验,其中24次容量反应阳性(阳性组)、29次容量反应阴性(阴性组)。PLR和uPLR试验后,阳性组患者SV、PP、PETCO2和VTCO2br均显著增加,且uPLR试验后SV和VTCO2br湿著高于PLR试验,分别是(81±22)mL比(77±19)mL和(27.1±6.1)mL比(25.2±6.2)mL,差异均有统计学意义(P<O.05);阴性组实验前后上述指标比较差异无统计学意义(P>0.05);PLR和uPLR后,△SV和△VTCO2br与补液后△SV成高度正相关(P<0.001)。PLR和uPLR试验后△SV、△PP、△VTCO2br和△PETCOC预测容量反应性ROC曲线下面积分别为0.92、0.85、0.86、0.77和0.94、O.84、0.87和0.77,灵敏度分别是83.30%、75.00%、79.16%、70.83%和87.50%、75.00%、83.33%、75.00%,特异度分别为89.65%、82.75%、86.20%、79.31%和93.10%、86.20%、89.65%、79.31%。结论uPLR试验可以提高预测容量反应的敏感性和特异性,△SV、△PP、△VTCO2br和△PETCO2等四项指标中△SV预测效果最好.展开更多
文摘Objective To examine the relationship between upper leg length （ULL） and metabolic syndrome （MetS） in older adults.Methods Data was collected from National Health and Nutritional Examination Survey （NHANES, 2009-2010）. 786 individuals （385 males and 401 females） who were 60 years of age or older were included in this analysis. MetS was defined as having at least three of following conditions, i.e., cen-tral obesity, dyslipidemia, insulin resistance, and hypertension based on National Cholesterol Education Program guidelines. ULL was grouped into gender-specific tertiles.Results328 （41.7%） of participants were categorized as having MetS （38.7% in men and 49.1% in women,P = 0.002）. Compared to individuals in the 1st tertile （T1） of ULL, those in the 3rd tertile （T3） had lower levels of triglycerides （120.8 vs. 153.1 mg/dL,P = 0.045）, waist circumference （100.7vs. 104.2 cm,P = 0.049）, and systolic blood pressure （126.7vs. 131.4 mmHg, P = 0.005）, but higher levels of high-density-lipoprotein cholesterol （58.1vs. 52.4 mg/dL,P = 0.024）. The odds ratios （95% CI） of MetS from multivariate logistic regression were 0.57 （0.32-1.03） for individuals in the T2 of ULL and 0.39 （0.24-0.64） for individuals in the T3 of ULL, respectively （P-value for the trend 0.022）.Conclusions ULL was negatively associated with MetS in older adults. Further research is needed to identify potential mechanisms.
文摘针对汽车行人保护碰撞试验中大腿冲击器的生物力学特性问题,采用THUMS(total human model for safety)人体模型与大腿冲击器进行对比仿真分析.模拟THUMS-SUV行人交通事故,并对THUMS人体模型大腿所受冲击力和弯矩进行了输出.根据事故中行人大腿初始碰撞条件和行人大腿最低能量状态,分别建立两种工况的行人大腿冲击器碰撞模型并进行模拟,对比分析行人大腿冲击器和THUMS人体模型大腿的动态响应、最大瞬间冲击力和最大弯矩.仿真结果表明:相对THUMS人体模型而言,大腿冲击器的最大瞬间冲击力偏高而最大弯矩偏低,行人小腿和上身的运动和接触作用,会影响大腿部位的接触力和最大弯矩,因此大腿冲击器的生物仿真度有待提高.
文摘目的探讨被动抬腿试验联合上肢抬高(PLR combined with upper limb elevation,uPLR)是否提高预测感染性休克病患者容量反应性的准确性。方法2014年10月-2017年10月入住徐州市第一医院重症医学科19例感染性休克患者纳入研究。采用脉搏指示连续心输出量及呼气二氧化碳监测技术监测被动抬腿试验(Passive leg raising,PLR)、uPLR和液体负荷试验前后患者每搏量(Stroke volume,SV)、脉压(pulse pressure,PP)、呼气二氧化碳容积(carbon dioxide of elimination of per breath,VTCO2br)和呼气末二氧化碳分压(end tidal carbon dioxide partial pressure,PETCO2)的变化情况,容量负荷试验后SV增加值(△SV)≥10%定义为容量反应阳性。采用ROC曲线分析PLR和uPLR预测容量反应性的准确性。结果19例患者行53次容量负荷试验,其中24次容量反应阳性(阳性组)、29次容量反应阴性(阴性组)。PLR和uPLR试验后,阳性组患者SV、PP、PETCO2和VTCO2br均显著增加,且uPLR试验后SV和VTCO2br湿著高于PLR试验,分别是(81±22)mL比(77±19)mL和(27.1±6.1)mL比(25.2±6.2)mL,差异均有统计学意义(P<O.05);阴性组实验前后上述指标比较差异无统计学意义(P>0.05);PLR和uPLR后,△SV和△VTCO2br与补液后△SV成高度正相关(P<0.001)。PLR和uPLR试验后△SV、△PP、△VTCO2br和△PETCOC预测容量反应性ROC曲线下面积分别为0.92、0.85、0.86、0.77和0.94、O.84、0.87和0.77,灵敏度分别是83.30%、75.00%、79.16%、70.83%和87.50%、75.00%、83.33%、75.00%,特异度分别为89.65%、82.75%、86.20%、79.31%和93.10%、86.20%、89.65%、79.31%。结论uPLR试验可以提高预测容量反应的敏感性和特异性,△SV、△PP、△VTCO2br和△PETCO2等四项指标中△SV预测效果最好.
