Background:The development of the kidneys and other organs of the urinary tract also follow the natural rule of gene-environment-lifestyle interaction.Both intrinsic and extrinsic factors may be associated with the et...Background:The development of the kidneys and other organs of the urinary tract also follow the natural rule of gene-environment-lifestyle interaction.Both intrinsic and extrinsic factors may be associated with the etiology of various kinds of urinary malformations.The environmental factors belong to extrinsic factors,which have attracted increasing attention from researchers.Methods:Publications about urinary malformations were searched from databases such as PubMed,Elsevier,Chemical Abstract,Excerpta Medica,Chinese Hospital Knowledge Database and Wanfang Database.Results:Urinary malformation is associated with low birth weight,maternal diseases,placental insufficiency,maternal drug exposure,and maternal exposure to environmental pesticides.Living environment and socioeconomic factors may also influence the incidence of urinary malformation.Conclusion:It is important to understand the association of environmental factors with the development of the renal system and urinary malformation in order to decrease the incidence of urinary malformations.展开更多
BACKGROUND Duplication of the renal pelvis is a common congenital malformation of the urinary system.About one-third of cases are complete unilateral duplication of the renal pelvis,while bilateral duplication is extr...BACKGROUND Duplication of the renal pelvis is a common congenital malformation of the urinary system.About one-third of cases are complete unilateral duplication of the renal pelvis,while bilateral duplication is extremely rare.Herein,we described a single case of bilateral renal duplication with double ureteral orifice ectopic vaginal fistula treated with laparoscopy.CASE SUMMARY A 6-year-old girl suffering from long-term vaginal leakage was admitted on June 10,2018.She was diagnosed with complete duplication of both kidneys and ureters and ectopic opening of both ureters combined with ureterovaginal fistula.The patient received laparoscopic ectopic ureteral bladder replantation and was followed up for 2 years.No renal function damage and vaginal leakage were found.CONCLUSION Laparoscopic bladder-ureter reimplantation could effectively determine the location and number of ectopic ureters by imaging and cystoscopy.展开更多
Objective To evaluate the monitoring and diagnostic potential of MR in fetal lung development using lung signal intensity changes in the fetus. Methods The lung-to-liver intensity ratio was calculated by means of regi...Objective To evaluate the monitoring and diagnostic potential of MR in fetal lung development using lung signal intensity changes in the fetus. Methods The lung-to-liver intensity ratio was calculated by means of region-of-interest analysis in all 35 fetuses including 7 bilateral urinary anomalies, 9 unilateral urinary anomalies, 5 pulmonary anomalies, and 14 others. Results All fetuses with urinary anomalies and pulmonary anomalies showed low ratio of lung-to-liver signal intensity. Conclusion Low ratio of lung-to-liver signal intensity on MR imaging indicates pulmonary hypoplasia after 22 weeks’ gestation.展开更多
基金supported by a grant from the 125 Talented Young Generation Program of the Third Xiangya Hospital of Central South University(xy3yy2013-125-02)
文摘Background:The development of the kidneys and other organs of the urinary tract also follow the natural rule of gene-environment-lifestyle interaction.Both intrinsic and extrinsic factors may be associated with the etiology of various kinds of urinary malformations.The environmental factors belong to extrinsic factors,which have attracted increasing attention from researchers.Methods:Publications about urinary malformations were searched from databases such as PubMed,Elsevier,Chemical Abstract,Excerpta Medica,Chinese Hospital Knowledge Database and Wanfang Database.Results:Urinary malformation is associated with low birth weight,maternal diseases,placental insufficiency,maternal drug exposure,and maternal exposure to environmental pesticides.Living environment and socioeconomic factors may also influence the incidence of urinary malformation.Conclusion:It is important to understand the association of environmental factors with the development of the renal system and urinary malformation in order to decrease the incidence of urinary malformations.
文摘BACKGROUND Duplication of the renal pelvis is a common congenital malformation of the urinary system.About one-third of cases are complete unilateral duplication of the renal pelvis,while bilateral duplication is extremely rare.Herein,we described a single case of bilateral renal duplication with double ureteral orifice ectopic vaginal fistula treated with laparoscopy.CASE SUMMARY A 6-year-old girl suffering from long-term vaginal leakage was admitted on June 10,2018.She was diagnosed with complete duplication of both kidneys and ureters and ectopic opening of both ureters combined with ureterovaginal fistula.The patient received laparoscopic ectopic ureteral bladder replantation and was followed up for 2 years.No renal function damage and vaginal leakage were found.CONCLUSION Laparoscopic bladder-ureter reimplantation could effectively determine the location and number of ectopic ureters by imaging and cystoscopy.
文摘Objective To evaluate the monitoring and diagnostic potential of MR in fetal lung development using lung signal intensity changes in the fetus. Methods The lung-to-liver intensity ratio was calculated by means of region-of-interest analysis in all 35 fetuses including 7 bilateral urinary anomalies, 9 unilateral urinary anomalies, 5 pulmonary anomalies, and 14 others. Results All fetuses with urinary anomalies and pulmonary anomalies showed low ratio of lung-to-liver signal intensity. Conclusion Low ratio of lung-to-liver signal intensity on MR imaging indicates pulmonary hypoplasia after 22 weeks’ gestation.