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Use of Network Pharmacology and Molecular Docking to Investigate the Mechanism by Which Ginseng Ameliorates Hypoxia 被引量:3
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作者 WANG Tao LI Hao Tian +7 位作者 WEI Shi Zhang CAI Hua Dan ZHU Yun LIU Hong Hong LI Yong Zhi WANG Jia Ping ZOU Wen Jun ZHAO Yan Ling 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第11期855-858,共4页
Hypoxia is a common pathological process in various clinical diseases and is characterized by abnormal changes in metabolism, function, and morphological structure of tissues resulting from insufficient oxygen supply ... Hypoxia is a common pathological process in various clinical diseases and is characterized by abnormal changes in metabolism, function, and morphological structure of tissues resulting from insufficient oxygen supply or oxygen barriers in tissues. In particular, hypoxia in vital organs such as the brain and heart is an important cause of death;. The prevention of tissue hypoxia and the 展开更多
关键词 In Use of Network Pharmacology and Molecular Docking to Investigate the Mechanism by Which Ginseng Ameliorates Hypoxia FIGURE
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STUDIES ON THE KINETICS AND INITIATION MECHANISM OF ACRYLAMIDE POLYMERIZATION USING CERIC/ACETOACETANILIDE SYSTEM AS INITIATOR
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《Chinese Chemical Letters》 SCIE CAS CSCD 1992年第2期103-106,共4页
It is found that acetoacetanilide possesses very high promoting reactivity towards ceric ion in initiating polymerization of vinyl monomer. The kinetics of acrylamide polymerization and the activation energies were st... It is found that acetoacetanilide possesses very high promoting reactivity towards ceric ion in initiating polymerization of vinyl monomer. The kinetics of acrylamide polymerization and the activation energies were studied. The initiation mechanism of ceric/acetoacetanilide is proposed on the basis of experimental results of FT-IR and ESR. 展开更多
关键词 AAA IV AS ESR STUDIES ON THE KINETICS AND INITIATION MECHANISM OF ACRYLAMIDE POLYMERIZATION USING CERIC/ACETOACETANILIDE SYSTEM AS INITIATOR
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A STUDY OF THE FORMATION OF LIVER METASTASIS AND ITS MECHANISM USING THE INTRASPLENIC INOCULATION OF CANCER CELLS
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作者 薛克勋 高进 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1989年第1期11-15,共5页
In order to establish an animal model with hepatic metastasis intrasplenic inoculation of carcinoma cells from murine uterine cervical carcinoma (U14) was employed. Results showed a high incidence of hepatic metastasi... In order to establish an animal model with hepatic metastasis intrasplenic inoculation of carcinoma cells from murine uterine cervical carcinoma (U14) was employed. Results showed a high incidence of hepatic metastasis could be obtained through the intrasplenic inoculation of 1 × 106 carcinoma cells. Removal of the primary carcinoma through splenec-tomy at different intervals after intrasplenic inoculation proved that the hepatic metastatic mechanism was not due to mechanical pressure but occurred spontaneously. This experimental model provides a useful means for studying the mechanism and prevention of hepatic metastasis. 展开更多
关键词 A STUDY OF THE FORMATION OF LIVER METASTASIS AND ITS MECHANISM USING THE INTRASPLENIC INOCULATION OF CANCER CELLS
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Mass transfer mechanisms in fixed-bed adsorption of erythromycin 被引量:2
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作者 Ying SUN Jiawen ZHU +2 位作者 Kui CHEN Sheng ZHU Jie XU 《Frontiers of Chemical Science and Engineering》 SCIE EI CSCD 2008年第4期353-360,共8页
The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performa... The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performance was investigated in a fixed-bed system with respect to the adsorption superficial velocity,ionic strength and pH.A mathematical model was used to simulate the mass transfer mechanism,taking film mass transfer,pore diffusion and axial dispersion into account.The model predictions were consistent with the experi-mental data and were consequently used to determine the mass transfer coefficients. 展开更多
关键词 fixed-bed adsorption superficial velocity ionic strength erythromycin However investigations on the parameters governing the performance of this technology are still scarce.In the present work a polymeric and porous resin Sepabeads SP825 resin was used for its higher adsorption efficiency compared with the resins reported.The equilib-rium capacity of Sepabeads SP825 for EM in a batch system was established using a Langmuir isotherm.The effects of superficial velocity ionic strength and pH on the adsorption process were determined from the results of fixed bed experiments.And a model of the purification process was used to simulate the mass transfer mechanism which has taken film mass transfer pore diffusion and axial dispersion into account.The experimental adsorp-tion measurements were compared to the results calcu-lated from the model.The completion of these studies provide some essential parameters which are required in order to design a successful purification process and better understand the fundamentals of these process.
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