The fabrication and characterization of p-i-n photodiodes integrated with wide spectrum focusing reflectors using nonperiodic strip and concentric-circular subwavelength gratings are presented. The experimental result...The fabrication and characterization of p-i-n photodiodes integrated with wide spectrum focusing reflectors using nonperiodic strip and concentric-circular subwavelength gratings are presented. The experimental results show that the gratings can reflect and focus the incident light on the absorber of the photodiode, and thus can simultaneously achieve high speed and high efficiency. For the gratings’ integrated photodiodes, the responsivity is improved over a wide spectral range, and when the absorber was 600 nm and the mesa diameter was40 μm, a responsivity of 0.46 A/W at a wavelength of 1.55 μm and a 3 dB bandwidth of 21.6 GHz under a reverse bias of 3 V were simultaneously obtained.展开更多
From the point of view of system design, a configuration of fiber-optic interferomet- ric hydrophone array and its modulation and demodulation approach using frequncy division multiplexing technique based on Phase Gen...From the point of view of system design, a configuration of fiber-optic interferomet- ric hydrophone array and its modulation and demodulation approach using frequncy division multiplexing technique based on Phase Generated Carrier (PGC) is introduced. And the em- phasis on demonstrating the relationship among the number of units N, the detectable signal amplitude D and the detectable frequency ws through analyzing the frequency spectrum of the output signal of the J × K array and the key factor which restricts N, D, Ws for increasing are presented. The maximum phare shift and the law of its variation according to frequency are specially analyzed. The results induced from some relative theory were verified by experiments.展开更多
Reverse genetics via targeted modification of gene sequences to obtain a phenotype and the inference of a gene's function or regulatory mechanism is widely used as a potent tool in viral biology and application.Ho...Reverse genetics via targeted modification of gene sequences to obtain a phenotype and the inference of a gene's function or regulatory mechanism is widely used as a potent tool in viral biology and application.However,while reverse genetics has contributed significantly to our understanding of molecular biology and the pathogenesis of viruses,its accessibility(operation)and openness(data)have raised many concerns regarding biosafety and biosecurity.In this review,we retrospectively examine the development of reverse genetics and its applications in virology,then emphasize global biosafety and biosecurity concerns regarding reverse genetics,and summarize global regulations,governance,and laws on reverse genetics.This review seeks to enhance our understanding and rational application of reverse genetics technology for the benefit of humankind.展开更多
基金funded by the National Natural Science Foundation of China(NSFC)(Nos.61574019,61674020,and 61274044)the 111 Project(No.B07005)+2 种基金the Beijing Municipality Natural Science Foundation(No.4132069)the Program for Changjiang ScholarsInnovative Research Team in University through the Ministry of Education of China(No.IRT0609)
文摘The fabrication and characterization of p-i-n photodiodes integrated with wide spectrum focusing reflectors using nonperiodic strip and concentric-circular subwavelength gratings are presented. The experimental results show that the gratings can reflect and focus the incident light on the absorber of the photodiode, and thus can simultaneously achieve high speed and high efficiency. For the gratings’ integrated photodiodes, the responsivity is improved over a wide spectral range, and when the absorber was 600 nm and the mesa diameter was40 μm, a responsivity of 0.46 A/W at a wavelength of 1.55 μm and a 3 dB bandwidth of 21.6 GHz under a reverse bias of 3 V were simultaneously obtained.
文摘From the point of view of system design, a configuration of fiber-optic interferomet- ric hydrophone array and its modulation and demodulation approach using frequncy division multiplexing technique based on Phase Generated Carrier (PGC) is introduced. And the em- phasis on demonstrating the relationship among the number of units N, the detectable signal amplitude D and the detectable frequency ws through analyzing the frequency spectrum of the output signal of the J × K array and the key factor which restricts N, D, Ws for increasing are presented. The maximum phare shift and the law of its variation according to frequency are specially analyzed. The results induced from some relative theory were verified by experiments.
文摘Reverse genetics via targeted modification of gene sequences to obtain a phenotype and the inference of a gene's function or regulatory mechanism is widely used as a potent tool in viral biology and application.However,while reverse genetics has contributed significantly to our understanding of molecular biology and the pathogenesis of viruses,its accessibility(operation)and openness(data)have raised many concerns regarding biosafety and biosecurity.In this review,we retrospectively examine the development of reverse genetics and its applications in virology,then emphasize global biosafety and biosecurity concerns regarding reverse genetics,and summarize global regulations,governance,and laws on reverse genetics.This review seeks to enhance our understanding and rational application of reverse genetics technology for the benefit of humankind.