Design Method for Optimizing the Interactive Interface of Live Broadcasting Platform for the Elderly Users

In the era of network live broadcasting for everyone,the development of live broadcasting platforms is also more intelligent and diversified.However,in the face of a large group of elderly users,the interface interaction design mode used is still mainly based on the interaction mode for young groups,and is not designed for elderly users.Therefore,a design method for optimizing the interaction interface of live broadcasting platform for elderly users was proposed in this study.Firstly,the case study method and Delphi expert survey method were used to determine the design needs of elderly users and the design mode was analysed.Secondly,the orthogonal design principle was used to design a test sample of the interactive interface of live broadcasting platform applicable for the elderly users,and then a user evaluation system was established to calculate the weights of the design elements using hierarchical analysis,and then the predictive relationship between the design mode of the interactive interface of live broadcasting platform and the elderly users was established by Quantitative Theory I.Finally,Genetic Algorithm was applied to generate the optimized design scheme.The results showed that the design method based on the Genetic Algorithm and the combination of Quantitative Theory can scientifically and effectively optimize the design of the interactive interface of the live broadcasting platform for the elderly users,and improve the experience of the elderly users.

Hepatitis B Surface Antigen and Hepatitis C Virus Antibodies among Drug Users in Burkina Faso

Introduction: The epidemiology of both hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among drug users (DUs) is little known in West Africa. The study aimed to assess the prevalence of hepatitis B and C viruses among drug users in Burkina Faso. Methodology: This was a cross-sectional biological and behavioral survey conducted between June and August 2022, among drug users in Ouagadougou and Bobo Dioulasso, the two main cities of Burkina Faso. A respondent-driven sampling (RDS) was used to recruit drug users. Hepatitis B surface antigen was determined using lateral flow rapid test kits and antibodies to hepatitis C virus in serum determined using an Enzyme-Linked Immunosorbent Assay. Data were entered and analyzed using Stata 17 software. Weighted binary logistic regression was used to identify the associated factors of hepatitis B and C infections and a p-value Results: A total of 323 drug users were recruited with 97.5% males. The mean age was 32.7 years old. The inhaled or smoked mode was the most used by drug users. The adjusted hepatitis B and hepatitis C prevalence among study participants were 11.1% and 2.3% respectively. The marital status (p = 0.001), and the nationality (p = 0.011) were significantly associated with hepatitis B infection. The type of drug used was not significantly associated with hepatitis B infection or hepatitis C infection. Conclusion: The prevalence of HBsAg and anti-HCV antibodies among DUs are comparable to those reported in the general population in Burkina Faso. This result suggests that the main routes of contamination by HBV and HCV among DUs are similar to those in the population, and could be explained by the low use of the injectable route by DUs in Burkina Faso.

Reform of the Irrigation Sector and Creation of Functional and Sustainable Irrigation Water Users Associations (AUEI) in Niger: Capitalization of the Experience of the Konni AHA

During the 1980s, as part of a policy of liberalization, following budgetary cuts linked to the implementation of structural adjustment programs, management responsibilities for AHAs were transferred from ONAHA to cooperatives concerned. Due to lack of financial resources, but also because of poor management, everywhere in Niger we are witnessing an accelerated deterioration of the irrigation infrastructure of hydro-agricultural developments. Institutional studies carried out on this situation led the State of Niger to initiate a reform of the governance of hydro-agricultural developments, by streng-thening the status of ONAHA, by creating an Association of Irrigation Water Users (AUEI) and by restructuring the old cooperatives. Indeed, this research aims to analyze the creation of functional and sustainable Irrigation Water User Associations (AUEI) in Niger in a context of reform of the irrigation sector, and based on the experience of the Konni AHA. It is based on a methodological approach which takes into account documentary research and the collection of data from 115 farmers, selected by reasoned choice and directly concerned by the management of the irrigated area. The data collected was analyzed and the results were analyzed using the systemic approach and the diagnostic process. The results show that the main mission of the AUEI is to ensure better management of water, hydraulic equipment and infrastructure on the hydro-agricultural developments of Konni. The creation of the Konni AUEI was possible thanks to massive support from the populations and authorities in the implementation process. After its establishment, the AUEI experienced a certain lethargy for some time due to the rehabilitation work of the AHA but currently it is functional and operational in terms of associative life and governance. Thus, the constraints linked to the legal system, the delay in the completion of the work, the uncertainties of access to irrigation water but also the problems linked to the change in mentality of certain ONAHA agents constitute the challenges that must be resolved in the short term for the operationalization of the Konni AUEI.

Evaluation of an Autonomous Vehicle User Interface for Sensory Impaired Users

Autonomous vehicles (AVs) hold immense promises in revolutionizing transportation, and their potential benefits extend to individuals with impairments, particularly those with vision and hearing impairments. However, the accommodation of these individuals in AVs requires developing advanced user interfaces. This paper describes an explorative study of a multimodal user interface for autonomous vehicles, specifically developed for passengers with sensory (vision and/or hearing) impairments. In a driving simulator, 32 volunteers with simulated sensory impairments, were exposed to multiple drives in an autonomous vehicle while freely interacting with standard and inclusive variants of the infotainment and navigation system interface. The two user interfaces differed in graphical layout and voice messages, which adopted inclusive design principles for the inclusive variant. Questionnaires and structured interviews were conducted to collect participants’ impressions. The data analysis reports positive user experiences, but also identifies technical challenges. Verified guidelines are provided for further development of inclusive user interface solutions.

Orthogonal Frequency Division Multiplexing Adaptive Technology for Multinode Users of Seawater Channel Based on Inductively Coupled Mooring Chain

As an important part of buoy-type ocean monitoring systems,the inductively coupled mooring chain solves the problem of data cotransmission through the multinode sensors that it carries,which is significant for the rapid acquisition of fish,hydrology,and other information.This paper is based on a seawater channel transmission model with a depth of 300 m and a bandwidth of 2 MHz.An orthogonal frequency division multiplexing(OFDM)technology is used to overcome the multipath effect of signal transmission on a seawater medium.The adaptive technology is integrated into the OFDM,and an improved joint subcarrier and bit power allocation algorithm is proposed.This algorithm solves the problem of dynamic subcarrier allocation during the cotransmission of underwater multinode user data in seawater channels.The results show that the algorithm complexity can be reduced by 0.18126×10^(-2)s during one complete OFDM system data transmission by the improved greedy algorithm,and a total of 216 bits are transmitted by the OFDM.The normalized channel capacity can be improved by 0.012 bit s^(-1)Hz^(-1).At the bit error ratio(BER)of 10^(-3),the BER performance can be improved by approximately 6 d B.When the numbers of users are 4 and 8,the improved algorithm increases the channel capacity,and the higher the number of users,the more evident the channel capacity improvement effect is.The results of this paper have an important reference value for enhancing the transmission performance of inductively coupled mooring chain underwater multinode data.

Trip Purposes of Automobile Users Inference Using Multi-day Traffic Monitoring Data

Determining trip purpose is an important link to explore travel rules. In this paper,we takea utomobile users in urban areas as the research object,combine unsupervised learning and supervised learningm ethods to analyze their travel characteristics,and focus on the classification and prediction of automobileu sers’trip purposes. However,previous studies on trip purposes mainly focused on questionnaires and GPSd ata,which cannot well reflect the characteristics of automobile travel. In order to avoid the multi-dayb ehavior variability and unobservable heterogeneity of individual characteristics ignored in traditional traffic questionnaires,traffic monitoring data from the Northern District of Qingdao are used,and the K-meansc lustering method is applied to estimate the trip purposes of automobile users. Then,Adaptive Boosting(AdaBoost)and Random Forest(RF)methods are used to classify and predict trip purposes. Finally,ther esult shows:(1)the purpose of automobile users can be mainly divided into four clusters,which includeC ommuting trips,Flexible life demand travel in daytime,Evening entertainment and leisure shopping,andT axi-based trips for the first three types of purposes,respectively;(2)the Random Forest method performss ignificantly better than AdaBoost in trip purpose prediction for higher accuracy;(3)the average predictiona ccuracy of Random Forest under hyper-parameters optimization reaches96.25%,which proves the feasibilitya nd rationality of the above clustering results.

Effects of Emotion on Decision-Making ofMethamphetamine Users: Based on theEmotional Iowa Gambling Task

The relapse of methamphetamine (meth) is associated with decision-making dysfunction. The present study aims to investigate theimpact of different emotions on the decision-making behavior of meth users. We used 2 (gender: male, female) × 3 (emotion:positive, negative, neutral) × 5 (block: 1, 2, 3, 4, 5) mixed experiment design. The study involved 168 meth users who weredivided into three groups: positive emotion, negative emotion and neutral emotion group, and tested by the emotional IowaGambling Task (IGT). The IGT performance of male users exhibited a decreasing trend from Block 1 to Block 3. Female methusers in positive emotion had the best performance in IGT than females in the other two groups. In positive emotion, the IGTperformance of female meth users was significantly better than that of men. Female meth users in positive emotion had betterdecision-making than those in negative or neutral emotion. Female meth users in positive emotion had better decision-makingperformance than males in positive emotion. In negative and neutral emotions, there was no significant gender difference indecision-making.

Reliable and Privacy-Preserving Federated Learning with Anomalous Users

Recently,various privacy-preserving schemes have been proposed to resolve privacy issues in federated learning(FL).However,most of them ignore the fact that anomalous users holding low-quality data may reduce the accuracy of trained models.Although some existing works manage to solve this problem,they either lack privacy protection for users’sensitive information or introduce a two-cloud model that is difficult to find in reality.A reliable and privacy-preserving FL scheme named reliable and privacy-preserving federated learning(RPPFL)based on a single-cloud model is proposed.Specifically,inspired by the truth discovery technique,we design an approach to identify the user’s reliability and thereby decrease the impact of anomalous users.In addition,an additively homomorphic cryptosystem is utilized to provide comprehensive privacy preservation(user’s local gradient privacy and reliability privacy).We give rigorous theoretical analysis to show the security of RPPFL.Based on open datasets,we conduct extensive experiments to demonstrate that RPPEL compares favorably with existing works in terms of efficiency and accuracy.

Identification of Influential Users in Online Social Network: A Brief Overview

Information networks where users join a network, publish their own content, and create links to other users are called Online Social Networks (OSNs). Nowadays, OSNs have become one of the major platforms to promote both new and viral applications as well as disseminate information. Social network analysis is the study of these information networks that leads to uncovering patterns of interaction among the entities. In this regard, finding influential users in OSNs is very important as they play a key role in the success above phenomena. Various approaches exist to detect influential users in OSNs, starting from simply counting the immediate neighbors to more complex machine-learning and message-passing techniques. In this paper, we review the recent existing research works that focused on identifying influential users in OSNs.

Survey of HIV Infection among Injection Drug Users in Guangdong, China

Objective： To understand the prevalence and behavioral risk factors of HIV infection among injection drug users in the Pearl River Delta Region （PRDR） of Guangdong province, and to provide evidence for establishing effective intervention strategies. Methods： Face to face interviews were conducted and serum samples from injection drug users from detoxification centers and the community were collected for HIV screening. Results： 655 drug users were recruited and interviewed. The HIV seropositive rate was 29.0%. 99.5 % of subjects were injection drug users （IDUs）, of whom,75.4% reported sharing injection equipment. Conclusion： HIV prevalence among injection drug users is high in the PRDR of Guangdong. Injection drug use is the principal behavioral risk factor for HIV transmission. Pragmatic harm reduction programs should be implemented to prevent the spread of HIV infection.

Study on Guidance of Users’Point of View to Construction of Urban Park in China——Inspiration by "Reflection on Urban Park:Public Space and Multi-culture"

New idea studying urban parks was opened up by "Reflection on Urban Park:Public Space and Multi-culture". By introducing anthropology into planning and design methodology of urban public space, it provided a new research method for the planning of urban park in our country. Through introduction and assessment of the book, existing problems and suggestions of the construction of our urban parks were proposed. In the perspective of urban parks' users, by the method of ethnology and anthropology, cultural diversity of urban public space would be investigated, paying attention to the usage behavior and different cultural characteristics, thinking about how to respect ecology and environmental construction of parks and coordinate the relation between culture and ecology while cultural diversity was respected. What should be considered in the construction of urban parks was not only culture but also ecological environment protection when culture was respected and citizens' interests during environment construction. These were also the fundamental problems needed to be considered and solved in parks' planning, construction and operation.

Proxy-Users系统收入分配的Stackelberg模型及解的存在性

用对策论的Stackelberg平衡理论研究了Proxy-Users系统中Proxy和Users之间分配收入问题.对Proxy和Users的地位不平等且Proxy不能按到达率提供服务的情况,建立了收入分配的Stackelberg策略模型,得到了一个双层规划模型,并证明了模型的解的存在性.

Analysis of cumulative handoff delay for graded secondary users in cognitive radio networks

According to the fact that the secondary users＇ delay requirements for data transmission are not unitary in cognitive radio networks, the secondary users are divided into two classes, denoted by SU1 and SU2, respectively. It is assumed that SU1 has a higher priority to occupy the primary users＇ unutilized channels than SU2. A preemptive resume priority M/G/1 queuing network is used to model the multiple spectrum handoffs processing. By using a state transition probability matrix and a cost matrix, the average cumulative delays of SU1 and SU2 are calculated, respectively. Numerical results show that the more the primary user＇s traffic load, the more rapidly the SU2＇s cumulative handoff delay grows. Compared with the networks where secondary users are unitary, the lower the SUI＇s arrival rate, the more obviously both SUI＇s and SU2＇s handoff delays decrease. The admission access regions limited by the maximum tolerable delay can also facilitate the design of admission control rules for graded secondary users.

A bright future for the tree shrew in neuroscience research:Summary from the inaugural Tree Shrew Users Meeting

Tree shrews(Tupaia spp.)have been used in neuroscience research since the 1960s due to their evolutionary proximity to primates.The use of and interest in this animal model have recently increased,in part due to the adaptation of modern neuroscience tools in this species.These tools include quantitative behavioral assays,calcium imaging,optogenetics and transgenics.To facilitate the exchange and development of these new technologies and associated research findings,we organized the inaugural“Tree Shrew Users Meeting”which was held online due to the COVID-19 pandemic.Here,we review this meeting and discuss the history of tree shrews as an animal model in neuroscience research and summarize the current themes being investigated using this animal,as well as future directions.

Prevalence of hepatitis C infection among intravenous drug users in Shanghai

AIM:To characterize the prevalence of hepatitis C virus(HCV)infection among Chinese intravenous drug users(IDUs).METHODS:A total of 432 adult IDUs(95 women and337 men)in Shanghai were included in the study.The third-generation Elecsys Anti-HCV assay(Roche Diagnostics GmbH,Sandhofer Strasse 116,D-68305,Mannheim,Germany)was used to screen for antibodies against HCV.The RIBA strip,a supplemental antiHCV test with high specificity,was performed on all of the samples that tested positive during the initial screening.All of the anti-HCV positive samples were analyzed with a Cobas TaqMan 48 Analyzer(Roche Diagnostics)for direct detection of HCV RNA.All of the HCV RNA-positive samples were sequenced for genotype determination.RESULTS:The preliminary screening identified 262(60.6%)subjects who were seropositive for HCV.Of the 62 females and 200 males seropositive subjects,16(16.7%)and 65(19.3%),respectively,were confirmed by RIBA,yielding an overall HCV seropositive rate of18.8%.Four female(6.5%)and 14 male(7.0%)subjects tested positive for HCV RNA,indicating an active infection rate of 4.2%for the entire study population.The 18 HCV RNA-positive serum samples were genotyped.Seven individuals were genotype 1b,and four were genotype 1a.One individual each was infected with genotypes 2a,2b and 3a.Four subjects were coinfected with multiple strains:two with genotypes 1a and 2a,and two with genotypes 1b and 2a.The active infection rate among HCV-seropositive individuals was22.2%,which was significantly lower than most estimates.CONCLUSION:The prevalence of HCV is relatively low among IDUs in Shanghai,with a spontaneous recovery rate much higher than previous estimates.

Hepatitis C in injection drug users: It is time to treat

Injection drug users(IDUs)are at risk of hepatitis C virus(HCV)infection,due to needle and syringe sharing.Chronic HCV infection is a major cause of liver-related morbidity and mortality but can be cured with antiviral treatment leading to sustained viral response(SVR).It is well demonstrated that,when close cooperation between specialists in drug addiction and psychiatrists is assured,patients on maintenance treatment with methadone/buprenorphine can be treated for HCV with response rate,tolerability and side effects similar to those reported in non-IDUs.Current guidelines recommend that active injection drug use should not exclude patients from HCV treatment,but many services remain reluctant to treat IDUs.No significant pharmacodynamic interactions were reported between approved direct anti-viral agents(DAAs)and buprenorphine or methadone.Dose adjustments are not recommended;therefore DAAs appear to be the"perfect"therapy for patients taking opiate substitutive therapy.These suggestions have been recently recognized by the European Association for the Study of the Liver(EASL)and included in EASL Recommendations on Treatment of Hepatitis C 2016.Guidelines confirm that HCV treatment for IDUs should be considered on an individualized basis and delivered within a multidisciplinary team setting;a history of intravenous drug use and recent drug use at treatment initiation are not associated with reduced SVR and decisions to treat must be made on a case-by-case basis.

Evaluation of Microblog Users’ Influence Based on PageRank and Users Behavior Analysis

This paper explores the uses’ influences on microblog. At first, according to the social network theory, we present an analysis of information transmitting network structure based on the relationship of following and followed phenomenon of microblog users. Informed by the microblog user behavior analysis, the paper also addresses a model for calculating weights of users’ influence. It proposes a U-R model, using which we can evaluate users’ influence based on PageRank algorithms and analyzes user behaviors. In the U-R model, the effect of user behaviors is explored and PageRank is applied to evaluate the importance and the influence of every user in a microblog network by repeatedly iterating their own U-R value. The users’ influences in a microblog network can be ranked by the U-R value. Finally, the validity of U-R model is proved with a real-life numerical example.

Study on the blood-borne virus co-infection and T lymphocyte subset among intravenous drug users

AIM： To investigate the features of various blood- borne virus infections and co-infection in intravenous drug users （IDUs）, and to examine the correlation of T lymphocyte subsets with virus co-infection. METHODS： Four hundred and six IDUs without any clinical manifestation of hepatitis and 102 healthy persons were enrolled in this study. HBV-DNA and HCV-RNA were detected by fluorescence quantitative PCR. HBsAg, HBeAg, anti-HBc, anti-HCV, HDV-Ag, anti-HGV, anti-HIV, and HCMV-IgM were assayed by enzyme-linked immunosorbent assay （ELISA） and immunochromatographic tests. The levels of Th1 and Th2 cytokines were measured by ELISA and radioactive immune assay （RIA）. The T lymphocyte subpopulation was detected by using fluorescence immunoassay. The similar indices taken from the healthy persons served as controls. RESULTS： The viral infection rate among IDUs was 36.45% for HBV, 69.7% for HCV, 47.3% for HIV, 2.22% for HDV, 1.97% for HGV, and 3.45% for HCMV. The co- infection rate of blood-borne virus was detected in 255 of 406 （62.81%） IDUs. More than 80% （161/192） of subjects infected with HIV were co-infected with the other viruses, such as HBV, HCV. In contrast, among the controls, the infection rate was 17.65% for HBV and 0% for the other viruses. Our investigation showed that there was a profound decrease in the proportion of CD4/CD8 and the percentage of CD3 and CD4, but not in the percentage of CD8. The levels of PHA-induced cytokines （IFN-γ and IL-4） and serum IL-2 were obviously decreased in IDUs. On the other hand, the level of serum IL-4 was increased. The level of IFN-γ and the percentage of CD4 were continuously decreased when the IDUs were infected with HIV or HIV co-infection. IDUs with HIV and HBV co-infection was 15.1% （29/192）. Of those 29 IDU with HIV and HBV co-infection, 51.72% （15/29） and 37.93% （11/29） were HBV-DNA-positive and HBeAg-positive, respectively. But, among IDUs without HIV infection, only 1.68% （2/119） of cases were HBV- DNA-positive.CONCLUSION： HCV, HBV and HIV infections are common in this population of IDU, leading to a high incidence of impaired Thl cytokine levels and CD4 lymphocyte. IDUs with HIV and HBV/HCV co-infection have lower expression of Th1 cytokine with enhancement of the Th2 response. HIV may be causing HBV replication by decreasing Thl function.

Analysis of users’ electricity consumption behavior based on ensemble clustering

Due to the increase in the number of smart meter devices,a power grid generates a large amount of data.Analyzing the data can help in understanding the users’electricity consumption behavior and demands;thus,enabling better service to be provided to them.Performing power load profile clustering is the basis for mining the users’electricity consumption behavior.By examining the complexity,randomness,and uncertainty of the users’electricity consumption behavior,this paper proposes an ensemble clustering method to analyze this behavior.First,principle component analysis(PCA)is used to reduce the dimensions of the data.Subsequently,the single clustering method is used,and the majority is selected for integrated clustering.As a result,the users’electricity consumption behavior is classified into different modes,and their characteristics are analyzed in detail.This paper examines the electricity power data of 19 real users in China for simulation purposes.This manuscript provides a thorough analysis along with suggestions for the users’weekly electricity consumption behavior.The results verify the effectiveness of the proposed method.

Epidemiology of Hepatitis B,C,D and G Viruses and Cytokine Levels among Intravenous Drug Users

To investigate the features of various hepatitis virus infection in intravenous drug users （IVDU）, we conducted an epidemiological survey of hepatitis viruses including hepatitis B virus （HBV）, hepatitis C virus （HCV）, hepatitis D virus （HDV） and hepatitis G virus （HGV） in IVDU. The correlation of Tn lymphocyte cytokine and hepatitis virus infection was examined. A. study population of 406 IVDU consisted of 383 males and 23 females. HBV-DNA and HCV-RNA were detected by fluorescence quantitative polymerase chain reaction. HBsAg, HBeAg, anti-HBc, anti-HCV, HDV-Ag and anti-HGV were assayed by ELISA. The levels of cytokines of TH1 and TH2 were measured by ELISA. The similar indices taken from 102 healthy persons served as controls. The infection rate of each virus among IVDU was 36.45% for HBV, 69. 7 % for HCV, 2.22 % for HDV, and 1.97 % for HGV, respectively. The co-infection rate of HBV and HCV was detected in 113 of 406 （27. 83 %）. In contrast, among controls, the infection rate was 17.65% for HBV and 0% for the other hepatitis viruses. The levels of PHA-induced cytokines （IFN-γ and IL-4） and the level of serum IL-2 were obviously decreased in IVDU. On the other hand, the level of serum IL-4 was increased. The IFN-γ level was continuously decreased when the IVDU was infected with HBV/HCV. In conclusion, HBV and HCV infection were common in this population of IVDU and they had led to a high incidence of impaired TH 1 cytokine levels.