The genus Tetrastigma belongs to the Vitaceae family and contains over 100 species.This paper reviewed folk uses,chemical constituents,pharmacological activities,and clinical applications of the medicinal plants in th...The genus Tetrastigma belongs to the Vitaceae family and contains over 100 species.This paper reviewed folk uses,chemical constituents,pharmacological activities,and clinical applications of the medicinal plants in the genus Tetrastigma.In addition,the paper also discussed the current problems for the further studies.Up to now,more than 240 compounds were reported from the genus Tetrastigma,covering 74 flavonoids,14 terpenoids,19 steroids,21 phenylpropanoids,14 alkaloids and others constituents.Among them,flavonoids are the major and the characteristic chemical constituents in this genus.Modern pharmacological studies and clinical practice showed that the extracts and chemical constituents of Tetrastigma species possessed wide pharmacological activities including antitumor,antioxidative,hepatoprotective,antiviral,anti-inflammatory,and analgesic activities.The information summarized in this paper provides valuable clues for new drug discovery and an incentive to expand the research of genus Tetrastigma.展开更多
基金the National Natural Science Foundation of China,China(No.81703819 and No.81874369)Hunan Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine(No.2017-04)+1 种基金Hunan Provincial Key Laboratory of Dong Medicine(No.2015TP1020-02)Students Research Innovative Program of Hunan Province(No.2018-413)。
文摘The genus Tetrastigma belongs to the Vitaceae family and contains over 100 species.This paper reviewed folk uses,chemical constituents,pharmacological activities,and clinical applications of the medicinal plants in the genus Tetrastigma.In addition,the paper also discussed the current problems for the further studies.Up to now,more than 240 compounds were reported from the genus Tetrastigma,covering 74 flavonoids,14 terpenoids,19 steroids,21 phenylpropanoids,14 alkaloids and others constituents.Among them,flavonoids are the major and the characteristic chemical constituents in this genus.Modern pharmacological studies and clinical practice showed that the extracts and chemical constituents of Tetrastigma species possessed wide pharmacological activities including antitumor,antioxidative,hepatoprotective,antiviral,anti-inflammatory,and analgesic activities.The information summarized in this paper provides valuable clues for new drug discovery and an incentive to expand the research of genus Tetrastigma.
