Objective:This study is to compare the personal acceptability and effect of Oral RU486/PG versus surgical vacuum aspiration on termination of early pregnancy.Method:Subjects were recruited by their voluntary choice of...Objective:This study is to compare the personal acceptability and effect of Oral RU486/PG versus surgical vacuum aspiration on termination of early pregnancy.Method:Subjects were recruited by their voluntary choice of methods.One hundred women aged 20~34 with amenorrhea of 35~42 days chose the medical method (RU486 600 mg on the lst day and cytotec 0.4 mg on the 3rd day).One hundred women aged 20~34 with amenorrhea<56 days chose vacuum aspiration. Subjects were asked to return on the 17th day in the medical group and 14th day in the surgical group for follow-up. Results:Complete abortion rates in the medical and surgical groups were 89% and 100% respectively. The main reason for choosing medical abortion was'less painful'(94% ) while that for choosing surgical abortion was'quick and saving time(55% ),with removing or insering IUD (45%) following surgical abortion'.Conclusion:For pregnancy termination RU486/Cytotec (PGE1) and vacuum aspiration are both highly acceptable.Each method has its own advantages and disadvantages and they can not replace each other.Selective use can provide advantages of either method. The earlier the termination,the safer the event.展开更多
Objective To access an ideal procedure terminating missed abortion within 12 weeks of gestational age. Methods Women with intrauterine fetal death were randomized into 3 groups. Group A (n=30): vaginal misoprostol ...Objective To access an ideal procedure terminating missed abortion within 12 weeks of gestational age. Methods Women with intrauterine fetal death were randomized into 3 groups. Group A (n=30): vaginal misoprostol (MP) 0.4 mg, 3 h before vacuum aspiration; group B(n=15): vaginal MP 0.4 mg every 3 h, up to 5 doses; group C(n=30): oral mifepristone (MF) 200 mg 36-48 h before vaginal MP 0.4 mg, MP was given every 3 h, up to 5 doses. Results Women in group A had the shortest interval of gestation tissue expulsion (3.2± 0.5 h) and the bleeding (3.2 ± 5.7 ml) during medical procedure, which were statistically significant in comparison with the other two groups (P〈0.001, P〈0.01, respectively). Success rates of groups A, B and C were 100%, 33.3% and 90.0%, respectively. Percentages of women need surgical interventions were similar in group B and group C(80.0%,76.7%, respectively). Bleeding during operation, pain after medical procedure and satisfaction presented no statistical significance among the 3 groups. Conclusion Vaginal MP followed by vacuum aspiration was valuable in safety, and efficacy, which led to less bleeding and a faster recovery.展开更多
文摘Objective:This study is to compare the personal acceptability and effect of Oral RU486/PG versus surgical vacuum aspiration on termination of early pregnancy.Method:Subjects were recruited by their voluntary choice of methods.One hundred women aged 20~34 with amenorrhea of 35~42 days chose the medical method (RU486 600 mg on the lst day and cytotec 0.4 mg on the 3rd day).One hundred women aged 20~34 with amenorrhea<56 days chose vacuum aspiration. Subjects were asked to return on the 17th day in the medical group and 14th day in the surgical group for follow-up. Results:Complete abortion rates in the medical and surgical groups were 89% and 100% respectively. The main reason for choosing medical abortion was'less painful'(94% ) while that for choosing surgical abortion was'quick and saving time(55% ),with removing or insering IUD (45%) following surgical abortion'.Conclusion:For pregnancy termination RU486/Cytotec (PGE1) and vacuum aspiration are both highly acceptable.Each method has its own advantages and disadvantages and they can not replace each other.Selective use can provide advantages of either method. The earlier the termination,the safer the event.
文摘Objective To access an ideal procedure terminating missed abortion within 12 weeks of gestational age. Methods Women with intrauterine fetal death were randomized into 3 groups. Group A (n=30): vaginal misoprostol (MP) 0.4 mg, 3 h before vacuum aspiration; group B(n=15): vaginal MP 0.4 mg every 3 h, up to 5 doses; group C(n=30): oral mifepristone (MF) 200 mg 36-48 h before vaginal MP 0.4 mg, MP was given every 3 h, up to 5 doses. Results Women in group A had the shortest interval of gestation tissue expulsion (3.2± 0.5 h) and the bleeding (3.2 ± 5.7 ml) during medical procedure, which were statistically significant in comparison with the other two groups (P〈0.001, P〈0.01, respectively). Success rates of groups A, B and C were 100%, 33.3% and 90.0%, respectively. Percentages of women need surgical interventions were similar in group B and group C(80.0%,76.7%, respectively). Bleeding during operation, pain after medical procedure and satisfaction presented no statistical significance among the 3 groups. Conclusion Vaginal MP followed by vacuum aspiration was valuable in safety, and efficacy, which led to less bleeding and a faster recovery.