AIM:To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome(DES)and associated laryngopharyngeal reflux(LPR).METHODS:The study was retrospective,open,observation...AIM:To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome(DES)and associated laryngopharyngeal reflux(LPR).METHODS:The study was retrospective,open,observational,and conducted in a real-life setting.Patients had pathological symptom assessment in dry eye(SANDE)and reflux symptom index(RSI)at baseline.Patients were re-assessed after 1mo and at the end of treatment.The treatment consisted of a three-month course based on the combined therapy:Gastroftal eye drops,one drop three times a day,and Gastroftal tablets,two tablets after lunch and two tablets after dinner.Tear break-up-time(TBUT)test,Schirmer test,RSI,and SANDE questionnaire were evaluated.RESULTS:The study included 253 patients.The mean age was 58±11.19y.TBUT test score and Schirmer’s test significantly increased(both P<0.001)after 1mo and at the end of treatment.The RSI score and SANDE scores significantly decreased(both P<0.001)after 1mo and at the end of treatment.CONCLUSION:The current,retrospective,and open study shows that combined therapy using Gastroftal eye drops and tablets could represent a valuable option in managing patients with DES associated with LPR.展开更多
Nowadays,combined steam and dry reforming of methane(CSDRM)is viewed as a new alternative for the production of high-quality syngas(termed as"metgas",H2:CO of 2.0)suitable for subsequent synthesis of methano...Nowadays,combined steam and dry reforming of methane(CSDRM)is viewed as a new alternative for the production of high-quality syngas(termed as"metgas",H2:CO of 2.0)suitable for subsequent synthesis of methanol,considered as a promising renewable energy vector to substitute fossil fuel resources.Adequate operation conditions(molar feed composition,temperature and pressure)are required for the sole production of"metgas"while achieving high CH4,CO2 and H2O conversion levels.In this work,thermodynamic equilibrium analysis of CSDRM has been performed using Gibbs free energy minimization where;(i)the effect of temperature(range:200-1000℃),(ii)feed composition(stoichiometric ratio as compared to a feed under excess steam or excess carbon dioxide),(iii)pressure(range:1-20 bar)and,(iv)the presence of a gaseous diluent on coke yields,reactivity levels and selectivity towards"metgas"were investigated.Running CSDRM at a temperature of at least 800℃,a pressure of 1 bar and under a feed composition where CO2-H2O/CH4 is around 1.0,are optimum conditions for the theoretical production of"metgas"while minimizing C(S)formation for longer experimental catalytic runs.A second part of this work presents a review of the recent progresses in the design of(principally)Ni-based catalysts along with some mechanistic and kinetic modeling aspects for the targeted CSDRM reaction.As compared to noble metals,their high availability,low cost and good intrinsic activity levels are main reasons for increasing research dedications in understanding deactivation potentials and providing amelioration strategies for further development.Deactivation causes and main orientations towards designing deactivationresistant supported Ni nanoparticles are clearly addressed and analyzed.Reported procedures based on salient catalytic features(i.e.,acidity/basicity character,redox properties,oxygen mobility,metal-support interaction)and recently employed innovative tactics(such as confinement within mesoporous systems,stabilization through core shell structures or on carbide surfaces)are highlighted and their impact on Ni0reactivity and stability are discussed.The final aspect of this review encloses the major directions and trends for improving synthesis/preparation designs of Ni-based catalysts for the sake of upgrading their usage into industrially oriented combined reforming operations.展开更多
Based on the experimental investigation of one-stage semi-circular impinging stream drying, the experiments with the two-stage semi-circular, as well as the vertical and semi-circular combined impinging stream drying ...Based on the experimental investigation of one-stage semi-circular impinging stream drying, the experiments with the two-stage semi-circular, as well as the vertical and semi-circular combined impinging stream drying were conducted. The variations of system pressure drop, the mean residence time of particles with the mass flow-rate ratio and air velocity etc, were determined. The influences of inlet air temperature, mass flow-rate ratio, initial moisture content of particles and air velocity etc. on drying characteristics were also studied. The results indicate that the vertical and semi-circular combined impinging stream drying can make full use of the advantages of both the vertical and semi-circular impinging stream drying. Reasonable mass flow-rate ratio, air velocity, and higher inlet air temperature should be used for less energy consumption and cost during drying process.展开更多
为了改善冻干鸡肉的生产效率及特性,利用超声波、菠萝蛋白酶、菠萝蛋白酶-超声波联合进行前处理,探究其对冻干鸡肉的影响。结果表明,经超声波、联合处理样品的干燥速率高于未处理组,联合处理样品的总失水率显著高于其他组(P<0.05);...为了改善冻干鸡肉的生产效率及特性,利用超声波、菠萝蛋白酶、菠萝蛋白酶-超声波联合进行前处理,探究其对冻干鸡肉的影响。结果表明,经超声波、联合处理样品的干燥速率高于未处理组,联合处理样品的总失水率显著高于其他组(P<0.05);联合处理样品的肌原纤维蛋白(myofibrillar protein,MP)溶解度以及电位绝对值显著高于其他组(P<0.05),其硬度、复水后嫩度、肌原纤维小片化指数(myofibril fragmentation index,MFI)、MP含量及平均粒径显著低于其他组(P<0.05);扫描电镜显示联合处理样品的肌原纤维断裂更明显;十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(sodium dodecyl sulfate-polyacrylamide gel electrophoresis,SDS-PAGE)显示联合处理能够降解肌球蛋白重链(myosin heavy chain,MHC)、肌动蛋白(actin)和原肌球蛋白(tropomyosin,TM),导致其条带变浅。联合处理有利于冻干鸡肉的制备生产以及感官、理化等特性的改善,能有效提高其品质。展开更多
[目的]研究热风-真空冷冻联合干燥对脆性龙眼果干品质及益生活性的影响,为高品质龙眼果干工业化节能干燥模式提供理论依据.[方法]以热风干燥、真空冷冻干燥龙眼果干为对照,比较分析热风-真空冷冻联合干燥对脆性龙眼果干水分含量、水分...[目的]研究热风-真空冷冻联合干燥对脆性龙眼果干品质及益生活性的影响,为高品质龙眼果干工业化节能干燥模式提供理论依据.[方法]以热风干燥、真空冷冻干燥龙眼果干为对照,比较分析热风-真空冷冻联合干燥对脆性龙眼果干水分含量、水分活度、皱缩率、复水比等理化特性和总糖、多糖等营养品质的影响.同时采用GC-MS测定风味物质变化,电量表测定能源消耗量.并选用植物乳杆菌和嗜酸乳杆菌发酵龙眼果干,比较发酵过程中活菌数、总糖、还原糖以及短链脂肪酸的变化,评价热风-真空冷冻联合干燥对龙眼体外益生活性的影响.[结果]热风-真空冷冻联合干燥龙眼果干的水分含量、水分活度和皱缩率显著低于热风干燥,而复水比显著高于热风干燥.在总糖、多糖含量以及挥发性风味物质种类和总量上,热风-真空冷冻联合干燥低于真空冷冻干燥而高于热风干燥.在能源消耗上,热风-真空冷冻联合干燥比真空冷冻干燥节约干燥时间12.16%,节约单位能耗25.40%.在益生活性方面,植物乳杆菌和嗜酸乳杆菌均能通过发酵龙眼干增加活菌数量,利用龙眼干中的总糖产生短链脂肪酸,降低发酵液pH,且益生效果受干燥方式和菌株种类的影响较大.当植物乳杆菌发酵热风-真空冷冻干燥的龙眼果干48 h后,活菌数生长最多可达12.40 lg cfu/mL,高于真空冷冻干燥、热风干燥和新鲜龙眼.嗜酸乳杆菌发酵48 h后,热风-真空冷冻联合干燥活菌数达11.84 lg cfu/mL,与真空冷冻干燥接近,低于热风干燥,但高于新鲜龙眼.[结论]热风-真空冷冻联合干燥结合了热风干燥和真空冷冻干燥两种干燥方式的特点,可以显著缩短干燥时间,节约能耗,提高干燥效率和果干品质.展开更多
To improve the quality and efficiency of sea cucumber drying,an orthogonal experiment of freeze and microwave vacuum combination drying technique was carried out.Factors and levels were FD time of conversion point(8 h...To improve the quality and efficiency of sea cucumber drying,an orthogonal experiment of freeze and microwave vacuum combination drying technique was carried out.Factors and levels were FD time of conversion point(8 h,16 h and 24 h),initial microwave power density(1.7 W/g,2.0 W/g and 2.3 W/g)and microwave intermittent ratio(12s-on/18s-off,14s-on/16s-off and 20s-on/10s-off).Results showed that the optimal parameters of FD-MVD were 8 h FD conversion point,1.7 W/g initial microwave power density,12 s-on/18 s-off microwave intermittent ratio,and the maximum rehydration rate of 280.71%,the lowest shrinkage rate of 14.48%,the least drying time of 9.25 h and energy consumption of 77316 kJ could be obtained.展开更多
Based on the analysis of air flow and heat transfer in the dry-cooling towerfor Harmon system, a combined iteration method is presented to solve the coupled heat transfer anddraft equations derived from theoretical an...Based on the analysis of air flow and heat transfer in the dry-cooling towerfor Harmon system, a combined iteration method is presented to solve the coupled heat transfer anddraft equations derived from theoretical and empirical formulas, with the size of the exchangers andthe cooling tower or the systematic parameters being determined. Taking the 686 MW unit as anexample, the present calculating results are well agreed with those of the real case, and thus themethod presented is practical and feasible for reasonable design of Harmon system.展开更多
The annual rainfall is low and the fresh water resources are scarce for the rainfed farming in dry zone of northern China,which seriously affects the sowing and growth of spring corn. In order to solve this problem,th...The annual rainfall is low and the fresh water resources are scarce for the rainfed farming in dry zone of northern China,which seriously affects the sowing and growth of spring corn. In order to solve this problem,the technology of ridge-mulching and side-sowing of spring corn is put forward,the supporting compound operation seeder is developed,and the effect of different speed on the quality of sowing is tested and analyzed. Under the test conditions described in this paper,the seeding operation with a high speed( up to 6 km/h) can be realized,and the quality of the seeding operation can meet the requirements of the national standards. The application of this machine can solve the problem of " drought damage at the booting stage" for spring corn,thereby realizing the deep fusion of farming machine and agronomy in dry farming of northern China,and achieving the integration of farming machine and agronomy.展开更多
文摘AIM:To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome(DES)and associated laryngopharyngeal reflux(LPR).METHODS:The study was retrospective,open,observational,and conducted in a real-life setting.Patients had pathological symptom assessment in dry eye(SANDE)and reflux symptom index(RSI)at baseline.Patients were re-assessed after 1mo and at the end of treatment.The treatment consisted of a three-month course based on the combined therapy:Gastroftal eye drops,one drop three times a day,and Gastroftal tablets,two tablets after lunch and two tablets after dinner.Tear break-up-time(TBUT)test,Schirmer test,RSI,and SANDE questionnaire were evaluated.RESULTS:The study included 253 patients.The mean age was 58±11.19y.TBUT test score and Schirmer’s test significantly increased(both P<0.001)after 1mo and at the end of treatment.The RSI score and SANDE scores significantly decreased(both P<0.001)after 1mo and at the end of treatment.CONCLUSION:The current,retrospective,and open study shows that combined therapy using Gastroftal eye drops and tablets could represent a valuable option in managing patients with DES associated with LPR.
基金financial support through the SOL-CARE(Energy-065,2016–2019)project(JC-ENERGY-2014 first call)。
文摘Nowadays,combined steam and dry reforming of methane(CSDRM)is viewed as a new alternative for the production of high-quality syngas(termed as"metgas",H2:CO of 2.0)suitable for subsequent synthesis of methanol,considered as a promising renewable energy vector to substitute fossil fuel resources.Adequate operation conditions(molar feed composition,temperature and pressure)are required for the sole production of"metgas"while achieving high CH4,CO2 and H2O conversion levels.In this work,thermodynamic equilibrium analysis of CSDRM has been performed using Gibbs free energy minimization where;(i)the effect of temperature(range:200-1000℃),(ii)feed composition(stoichiometric ratio as compared to a feed under excess steam or excess carbon dioxide),(iii)pressure(range:1-20 bar)and,(iv)the presence of a gaseous diluent on coke yields,reactivity levels and selectivity towards"metgas"were investigated.Running CSDRM at a temperature of at least 800℃,a pressure of 1 bar and under a feed composition where CO2-H2O/CH4 is around 1.0,are optimum conditions for the theoretical production of"metgas"while minimizing C(S)formation for longer experimental catalytic runs.A second part of this work presents a review of the recent progresses in the design of(principally)Ni-based catalysts along with some mechanistic and kinetic modeling aspects for the targeted CSDRM reaction.As compared to noble metals,their high availability,low cost and good intrinsic activity levels are main reasons for increasing research dedications in understanding deactivation potentials and providing amelioration strategies for further development.Deactivation causes and main orientations towards designing deactivationresistant supported Ni nanoparticles are clearly addressed and analyzed.Reported procedures based on salient catalytic features(i.e.,acidity/basicity character,redox properties,oxygen mobility,metal-support interaction)and recently employed innovative tactics(such as confinement within mesoporous systems,stabilization through core shell structures or on carbide surfaces)are highlighted and their impact on Ni0reactivity and stability are discussed.The final aspect of this review encloses the major directions and trends for improving synthesis/preparation designs of Ni-based catalysts for the sake of upgrading their usage into industrially oriented combined reforming operations.
基金supported by the National Natural Science Foundation of China(Key Project No.5873610)Chinese Academy Sciences(Key Project No.KJ951-131-704)+1 种基金Chinese National Key Foundation Research Subject(No.G2000026305)the Director Foundation of Institute of Engineering Thermophysics,Chinese Academy Sciences.
文摘Based on the experimental investigation of one-stage semi-circular impinging stream drying, the experiments with the two-stage semi-circular, as well as the vertical and semi-circular combined impinging stream drying were conducted. The variations of system pressure drop, the mean residence time of particles with the mass flow-rate ratio and air velocity etc, were determined. The influences of inlet air temperature, mass flow-rate ratio, initial moisture content of particles and air velocity etc. on drying characteristics were also studied. The results indicate that the vertical and semi-circular combined impinging stream drying can make full use of the advantages of both the vertical and semi-circular impinging stream drying. Reasonable mass flow-rate ratio, air velocity, and higher inlet air temperature should be used for less energy consumption and cost during drying process.
文摘为了改善冻干鸡肉的生产效率及特性,利用超声波、菠萝蛋白酶、菠萝蛋白酶-超声波联合进行前处理,探究其对冻干鸡肉的影响。结果表明,经超声波、联合处理样品的干燥速率高于未处理组,联合处理样品的总失水率显著高于其他组(P<0.05);联合处理样品的肌原纤维蛋白(myofibrillar protein,MP)溶解度以及电位绝对值显著高于其他组(P<0.05),其硬度、复水后嫩度、肌原纤维小片化指数(myofibril fragmentation index,MFI)、MP含量及平均粒径显著低于其他组(P<0.05);扫描电镜显示联合处理样品的肌原纤维断裂更明显;十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(sodium dodecyl sulfate-polyacrylamide gel electrophoresis,SDS-PAGE)显示联合处理能够降解肌球蛋白重链(myosin heavy chain,MHC)、肌动蛋白(actin)和原肌球蛋白(tropomyosin,TM),导致其条带变浅。联合处理有利于冻干鸡肉的制备生产以及感官、理化等特性的改善,能有效提高其品质。
文摘[目的]研究热风-真空冷冻联合干燥对脆性龙眼果干品质及益生活性的影响,为高品质龙眼果干工业化节能干燥模式提供理论依据.[方法]以热风干燥、真空冷冻干燥龙眼果干为对照,比较分析热风-真空冷冻联合干燥对脆性龙眼果干水分含量、水分活度、皱缩率、复水比等理化特性和总糖、多糖等营养品质的影响.同时采用GC-MS测定风味物质变化,电量表测定能源消耗量.并选用植物乳杆菌和嗜酸乳杆菌发酵龙眼果干,比较发酵过程中活菌数、总糖、还原糖以及短链脂肪酸的变化,评价热风-真空冷冻联合干燥对龙眼体外益生活性的影响.[结果]热风-真空冷冻联合干燥龙眼果干的水分含量、水分活度和皱缩率显著低于热风干燥,而复水比显著高于热风干燥.在总糖、多糖含量以及挥发性风味物质种类和总量上,热风-真空冷冻联合干燥低于真空冷冻干燥而高于热风干燥.在能源消耗上,热风-真空冷冻联合干燥比真空冷冻干燥节约干燥时间12.16%,节约单位能耗25.40%.在益生活性方面,植物乳杆菌和嗜酸乳杆菌均能通过发酵龙眼干增加活菌数量,利用龙眼干中的总糖产生短链脂肪酸,降低发酵液pH,且益生效果受干燥方式和菌株种类的影响较大.当植物乳杆菌发酵热风-真空冷冻干燥的龙眼果干48 h后,活菌数生长最多可达12.40 lg cfu/mL,高于真空冷冻干燥、热风干燥和新鲜龙眼.嗜酸乳杆菌发酵48 h后,热风-真空冷冻联合干燥活菌数达11.84 lg cfu/mL,与真空冷冻干燥接近,低于热风干燥,但高于新鲜龙眼.[结论]热风-真空冷冻联合干燥结合了热风干燥和真空冷冻干燥两种干燥方式的特点,可以显著缩短干燥时间,节约能耗,提高干燥效率和果干品质.
基金Vitalization Project of Liaoning Education Department for supporting the research under the contract of No.2004A102。
文摘To improve the quality and efficiency of sea cucumber drying,an orthogonal experiment of freeze and microwave vacuum combination drying technique was carried out.Factors and levels were FD time of conversion point(8 h,16 h and 24 h),initial microwave power density(1.7 W/g,2.0 W/g and 2.3 W/g)and microwave intermittent ratio(12s-on/18s-off,14s-on/16s-off and 20s-on/10s-off).Results showed that the optimal parameters of FD-MVD were 8 h FD conversion point,1.7 W/g initial microwave power density,12 s-on/18 s-off microwave intermittent ratio,and the maximum rehydration rate of 280.71%,the lowest shrinkage rate of 14.48%,the least drying time of 9.25 h and energy consumption of 77316 kJ could be obtained.
基金This project is supported by Main Project in Shanghai for the Combination of New technology and Production(No.9120902)Selected from Proceedings of 2000 the First International conference on Mechanical Engineering
文摘Based on the analysis of air flow and heat transfer in the dry-cooling towerfor Harmon system, a combined iteration method is presented to solve the coupled heat transfer anddraft equations derived from theoretical and empirical formulas, with the size of the exchangers andthe cooling tower or the systematic parameters being determined. Taking the 686 MW unit as anexample, the present calculating results are well agreed with those of the real case, and thus themethod presented is practical and feasible for reasonable design of Harmon system.
基金Supported by Project of Bohai Granary in Hebei Province(2013BAD05B0504)Science and Technology Innovation Project of Hebei Academy of Agriculture and Forestry Sciences(F17C10007-4)
文摘The annual rainfall is low and the fresh water resources are scarce for the rainfed farming in dry zone of northern China,which seriously affects the sowing and growth of spring corn. In order to solve this problem,the technology of ridge-mulching and side-sowing of spring corn is put forward,the supporting compound operation seeder is developed,and the effect of different speed on the quality of sowing is tested and analyzed. Under the test conditions described in this paper,the seeding operation with a high speed( up to 6 km/h) can be realized,and the quality of the seeding operation can meet the requirements of the national standards. The application of this machine can solve the problem of " drought damage at the booting stage" for spring corn,thereby realizing the deep fusion of farming machine and agronomy in dry farming of northern China,and achieving the integration of farming machine and agronomy.
