In this paper, we aim to find eventually vanished solutions, a special class of bounded solutions which tend to 0 as t → ±∞), to a Lienard system with a time-dependent force. Since it is not a Hamiltonian syst...In this paper, we aim to find eventually vanished solutions, a special class of bounded solutions which tend to 0 as t → ±∞), to a Lienard system with a time-dependent force. Since it is not a Hamiltonian system with small perturbations, the well-known Melnikov method is not applicable to the determination of the existence of eventually vanished solutions. We use a sequence of periodically forced systems to approximate the considered system, and find their periodic solutions. Difficulties caused by the non- Hamiltonian form are overcome by applying the Schauder's fixed point theorem. We show that the sequence of the periodic solutions has an accumulation giving an eventually vanished solution of the forced Lienard system.展开更多
In this paper,we present some vanishing theorems for p-harmonic forms on-super stable complete submanifold M immersed in sphere Sn+m.When 2≤1≤n-2,M has a flat normal bundle.Assuming that M is a minimal submanifold ...In this paper,we present some vanishing theorems for p-harmonic forms on-super stable complete submanifold M immersed in sphere Sn+m.When 2≤1≤n-2,M has a flat normal bundle.Assuming that M is a minimal submanifold andδ>1(n-1)p2/4n[p-1+(p-1)2kp],we prove a vanishing theorem for p-harmonicℓ-forms.展开更多
In this paper,we study the global existence of BV solutions of the initial value problem for the isentropic p-system,where the state equation of the gas is given by P=Av^(-γ).Forγ>1,the general existence result f...In this paper,we study the global existence of BV solutions of the initial value problem for the isentropic p-system,where the state equation of the gas is given by P=Av^(-γ).Forγ>1,the general existence result for large initial data has not been obtained.By using the Glimm scheme,Nishida,Smoller and Diperna successively obtained the global existence results for(γ-1)TV(v_(0)(x),u_(0)(x))being small.In the present paper,by adopting a rescaling technique,we improve these results and obtain the global existence result under the condition that(γ-1)^(γ+1)(TV(v_(0)(x)))~(γ-1)(TV(u_(0)(x)))^(2) is small,which implies that,for fixedγ>1,either TV(v_(0)(x))or TV(u_(0)(x))can be arbitrarily large.展开更多
Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with...Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes.展开更多
Vanishing bone disease(Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by de struction of osseous matrix and proliferation of vascula structures, resulting in destruction and absorption o bo...Vanishing bone disease(Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by de struction of osseous matrix and proliferation of vascula structures, resulting in destruction and absorption o bone. Despite the extensive investigation of the patho genetic mechanisms of the disease, its etiology hasn'been clarified and several theories exist. The syndrome can affect one or multiple bones of the patient, includ ing the skull, the upper and lower extremities, the spine and pelvis. The clinical presentation of a patient suffer ing from vanishing bone disease includes, pain, func tional impairment and swelling of the affected region although asymptomatic cases have been reported, as well as cases in which the diagnosis was made after a pathologic fracture. In this short review we summarize the theories regarding the etiology as well as the clini cal presentation, the diagnostic approach and treat ment options of this rare disease.展开更多
Vanishing bile duct syndrome (VBDS) refers to a group of disorders characterized by prolonged cholestasis as a result of destruction and disappearance ofintrahepatic bile ducts. Multiple etiologies have been indentifi...Vanishing bile duct syndrome (VBDS) refers to a group of disorders characterized by prolonged cholestasis as a result of destruction and disappearance ofintrahepatic bile ducts. Multiple etiologies have been indentifi ed including infections, neoplastic disorders, autoimmune conditions and drugs. The natural history of this condition is variable and may involve resolution of cholestasis or progression with irreversible damage. VBDS is extremely rare in human immunodeficiency virus (HIV)-infected patients and anti-retroviral therapy has never been implicated as a cause. We encountered a young pregnant female with HIV and VBDS secondary to anti-retroviral therapy. Here, we report her clinical course and outcome.展开更多
In this paper, we study the vanishing viscosity limit for non-isentropic gas dy- namics with interacting shocks. Given any entropy solution of non-isentropic gas dynamics which consists of two different families of sh...In this paper, we study the vanishing viscosity limit for non-isentropic gas dy- namics with interacting shocks. Given any entropy solution of non-isentropic gas dynamics which consists of two different families of shocks interacting at some positive time, we show that such solution is the vanishing viscosity limit of a family of smooth global solutions for a viscous system of conservation law. We remark that, after the interacting time, not only shocks but also contact discontinuity are generated.展开更多
In this paper, the authors get the characterizations of the integral and Car-leson type measure both associated with the invariant gradient for little a-Bloch functions in the unit ball of Cn. As a consequence, some r...In this paper, the authors get the characterizations of the integral and Car-leson type measure both associated with the invariant gradient for little a-Bloch functions in the unit ball of Cn. As a consequence, some results of Ouyang C H, Yang W S and Zhao R H in [4] and a result of Yang W S in [10] are extended.展开更多
This article is concerned with the pointwise error estimates for vanishing vis- cosity approximations to scalar convex conservation laws with boundary.By the weighted error function and a bootstrap extrapolation techn...This article is concerned with the pointwise error estimates for vanishing vis- cosity approximations to scalar convex conservation laws with boundary.By the weighted error function and a bootstrap extrapolation technique introduced by Tadmor-Tang,an optimal pointwise convergence rate is derived for the vanishing viscosity approximations to the initial-boundary value problem for scalar convex conservation laws,whose weak entropy solution is piecewise C 2 -smooth with interaction of elementary waves and the ...展开更多
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to induce liver injury. Patterns of the injury usually range from mild elevations of liver enzymes to sometimes severe fulminant hepatic fai...BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to induce liver injury. Patterns of the injury usually range from mild elevations of liver enzymes to sometimes severe fulminant hepatic failure. Likewise, naproxen is a propionic acid derivative NSAID that was introduced in 1980 and has been available as an over-the- counter medication since 1994, but has rarely been reported to cause liver injury. METHODS: We treated a 30-year-old woman with jaundice and intractable pruritus that developed shortly after taking naproxen. We reviewed the medical history and liver histopathology of the patient as well as all previously published case reports of naproxen-associated liver toxicity in the English language literature. RESULTS: The liver biochemical profile of the patient revealed a mixed cholestasis and hepatitis pattern. Consecutive liver biopsies demonstrated focal lobular inflammation, hepatocyte drop-out, and a progressive loss of the small interlobular bile ducts (ductopenia). The biopsy performed two years after onset of the disease showed partial recovery of a small number of bile ducts; however, 10 years passed before the biochemical profile returned to near normal. CONCLUSIONS: Naproxen-associated liver toxicity remains a rare entity, but should be considered in any patient presenting with cholestasis shortly after its use. Liver injury is most commonly seen in a mixed pattern characterized by cholestasis and hepatitis. The resulting liver damage may take years to resolve.展开更多
Using non-linear connection of Finsler manifold M, the existence of local coordinates which is normalized at a point x is proved, and the Laplace operator A on 1-form of M is defined by non-linear connection and its c...Using non-linear connection of Finsler manifold M, the existence of local coordinates which is normalized at a point x is proved, and the Laplace operator A on 1-form of M is defined by non-linear connection and its curvature tensor. After proving the maximum principle theorem of Hopf-Bochner on M, the Bochner type vanishing theorem of Killing vectors and harmonic 1-form are obtained.展开更多
The paper aims to estimate the thickness of the boundary layer for the planar MHD system with vanishing shear viscosity μ. Under some conditions on the initial and boundary data, we show that the thickness is of the ...The paper aims to estimate the thickness of the boundary layer for the planar MHD system with vanishing shear viscosity μ. Under some conditions on the initial and boundary data, we show that the thickness is of the order √μ|lnμ|. Note that this estimate holds also for the Navier-Stokes system so that it extends the previous works even without the magnetic effect.展开更多
This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the fre...This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the free boundary problem studied by Kim et al.(An SIR epidemic model with free boundary.Nonlinear Anal RWA,2013,14:1992-2001).We first prove that this problem has a unique solution defined for all time,and then we give sufficient conditions for the disease vanishing and spreading.Our result shows that the disease will not spread if the basic reproduction number R_(0)<1,or the initial infected area h_(0),expanding ability μ and the initial datum S_(0) are all small enough when 1<R_(0)<1+d/μ_(2)+α.Furthermore,we show that if 1<R_(0)<1+d/μ_(2)+α,the disease will spread when h_(0) is large enough or h_(0) is small but μ is large enough.It is expected that the disease will always spread when R_(0)≥1+d/μ_(2)+α which is different from the local model.展开更多
The aim of this paper is to prove the well-posedness(existence and uniqueness) of the L p entropy solution to the homogeneous Dirichlet problems for the anisotropic degenerate parabolic-hyperbolic equations with L p...The aim of this paper is to prove the well-posedness(existence and uniqueness) of the L p entropy solution to the homogeneous Dirichlet problems for the anisotropic degenerate parabolic-hyperbolic equations with L p initial value.We use the device of doubling variables and some technical analysis to prove the uniqueness result.Moreover we can prove that the L p entropy solution can be obtained as the limit of solutions of the corresponding regularized equations of nondegenerate parabolic type.展开更多
In this paper, we show the asymptotic limit for the 3D Boussinesq system with zero viscosity limit or zero diffusivity limit. By the classical energy method, we prove that as viscosity(or diffusivity) coefficient goes...In this paper, we show the asymptotic limit for the 3D Boussinesq system with zero viscosity limit or zero diffusivity limit. By the classical energy method, we prove that as viscosity(or diffusivity) coefficient goes to zero the solutions of the fully viscous equations converges to those of zero viscosity(or zero diffusivity) equations, which extend the previous results on the asymptotic limit under the conditions of the zero parameter(zero viscosity ν = 0 or zero diffusivity η = 0) in 2D case separately.展开更多
The lifting scheme is a custom design construclion of Biorthogonal wavelets, a fast and efficient method to realize wavelet transform,which provides a wider range of application and efficiently reduces the computing t...The lifting scheme is a custom design construclion of Biorthogonal wavelets, a fast and efficient method to realize wavelet transform,which provides a wider range of application and efficiently reduces the computing time with its particular frame. This paper aims at introducing the second generation wavelets, begins with traditional Mallat algorithms, illustrates the lifting scheme and brings out the detail steps in the construction of Biorthogonal wavelets. Because of isolating the degrees of freedom remaining the biorthogonality relations, we can fully control over the lifting operators to design the wavelet for a particular application, such as increasing the number of the vanishing moments.展开更多
Vanishing white matter (VWM) disease - a disease of the cytosolic translation machinery: VWM is a recessive genet- ic neurodegenerative disease caused by mutations in any of the five genes encoding the subunits of ...Vanishing white matter (VWM) disease - a disease of the cytosolic translation machinery: VWM is a recessive genet- ic neurodegenerative disease caused by mutations in any of the five genes encoding the subunits of translation initiation factor 2B (eIF2B) (Leegwater et al., 2001; OMIM 306896).展开更多
文摘In this paper, we aim to find eventually vanished solutions, a special class of bounded solutions which tend to 0 as t → ±∞), to a Lienard system with a time-dependent force. Since it is not a Hamiltonian system with small perturbations, the well-known Melnikov method is not applicable to the determination of the existence of eventually vanished solutions. We use a sequence of periodically forced systems to approximate the considered system, and find their periodic solutions. Difficulties caused by the non- Hamiltonian form are overcome by applying the Schauder's fixed point theorem. We show that the sequence of the periodic solutions has an accumulation giving an eventually vanished solution of the forced Lienard system.
文摘In this paper,we present some vanishing theorems for p-harmonic forms on-super stable complete submanifold M immersed in sphere Sn+m.When 2≤1≤n-2,M has a flat normal bundle.Assuming that M is a minimal submanifold andδ>1(n-1)p2/4n[p-1+(p-1)2kp],we prove a vanishing theorem for p-harmonicℓ-forms.
基金partially the NSFC(11671193)Fangqi Chen was partially the NSFC(12172166,11872201)。
文摘In this paper,we study the global existence of BV solutions of the initial value problem for the isentropic p-system,where the state equation of the gas is given by P=Av^(-γ).Forγ>1,the general existence result for large initial data has not been obtained.By using the Glimm scheme,Nishida,Smoller and Diperna successively obtained the global existence results for(γ-1)TV(v_(0)(x),u_(0)(x))being small.In the present paper,by adopting a rescaling technique,we improve these results and obtain the global existence result under the condition that(γ-1)^(γ+1)(TV(v_(0)(x)))~(γ-1)(TV(u_(0)(x)))^(2) is small,which implies that,for fixedγ>1,either TV(v_(0)(x))or TV(u_(0)(x))can be arbitrarily large.
基金Supported by The Intramural Research Programs of the National Institutes of Health Clinical Center and the National Institute of Allergy and Infectious Diseases
文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes.
文摘Vanishing bone disease(Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by de struction of osseous matrix and proliferation of vascula structures, resulting in destruction and absorption o bone. Despite the extensive investigation of the patho genetic mechanisms of the disease, its etiology hasn'been clarified and several theories exist. The syndrome can affect one or multiple bones of the patient, includ ing the skull, the upper and lower extremities, the spine and pelvis. The clinical presentation of a patient suffer ing from vanishing bone disease includes, pain, func tional impairment and swelling of the affected region although asymptomatic cases have been reported, as well as cases in which the diagnosis was made after a pathologic fracture. In this short review we summarize the theories regarding the etiology as well as the clini cal presentation, the diagnostic approach and treat ment options of this rare disease.
文摘Vanishing bile duct syndrome (VBDS) refers to a group of disorders characterized by prolonged cholestasis as a result of destruction and disappearance ofintrahepatic bile ducts. Multiple etiologies have been indentifi ed including infections, neoplastic disorders, autoimmune conditions and drugs. The natural history of this condition is variable and may involve resolution of cholestasis or progression with irreversible damage. VBDS is extremely rare in human immunodeficiency virus (HIV)-infected patients and anti-retroviral therapy has never been implicated as a cause. We encountered a young pregnant female with HIV and VBDS secondary to anti-retroviral therapy. Here, we report her clinical course and outcome.
基金Xiaoding Shi was supported by National Natural Sciences Foundation of China(11471321)Yan Yong was supported by National Natural Sciences Foundation of China(11201301)
文摘In this paper, we study the vanishing viscosity limit for non-isentropic gas dy- namics with interacting shocks. Given any entropy solution of non-isentropic gas dynamics which consists of two different families of shocks interacting at some positive time, we show that such solution is the vanishing viscosity limit of a family of smooth global solutions for a viscous system of conservation law. We remark that, after the interacting time, not only shocks but also contact discontinuity are generated.
文摘In this paper, the authors get the characterizations of the integral and Car-leson type measure both associated with the invariant gradient for little a-Bloch functions in the unit ball of Cn. As a consequence, some results of Ouyang C H, Yang W S and Zhao R H in [4] and a result of Yang W S in [10] are extended.
基金supported by the NSF China#10571075NSF-Guangdong China#04010473+1 种基金The research of the second author was supported by Jinan University Foundation#51204033the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State education Ministry#2005-383
文摘This article is concerned with the pointwise error estimates for vanishing vis- cosity approximations to scalar convex conservation laws with boundary.By the weighted error function and a bootstrap extrapolation technique introduced by Tadmor-Tang,an optimal pointwise convergence rate is derived for the vanishing viscosity approximations to the initial-boundary value problem for scalar convex conservation laws,whose weak entropy solution is piecewise C 2 -smooth with interaction of elementary waves and the ...
文摘BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to induce liver injury. Patterns of the injury usually range from mild elevations of liver enzymes to sometimes severe fulminant hepatic failure. Likewise, naproxen is a propionic acid derivative NSAID that was introduced in 1980 and has been available as an over-the- counter medication since 1994, but has rarely been reported to cause liver injury. METHODS: We treated a 30-year-old woman with jaundice and intractable pruritus that developed shortly after taking naproxen. We reviewed the medical history and liver histopathology of the patient as well as all previously published case reports of naproxen-associated liver toxicity in the English language literature. RESULTS: The liver biochemical profile of the patient revealed a mixed cholestasis and hepatitis pattern. Consecutive liver biopsies demonstrated focal lobular inflammation, hepatocyte drop-out, and a progressive loss of the small interlobular bile ducts (ductopenia). The biopsy performed two years after onset of the disease showed partial recovery of a small number of bile ducts; however, 10 years passed before the biochemical profile returned to near normal. CONCLUSIONS: Naproxen-associated liver toxicity remains a rare entity, but should be considered in any patient presenting with cholestasis shortly after its use. Liver injury is most commonly seen in a mixed pattern characterized by cholestasis and hepatitis. The resulting liver damage may take years to resolve.
基金Project supported by the Natural Science Foundation of China(10271097)
文摘Using non-linear connection of Finsler manifold M, the existence of local coordinates which is normalized at a point x is proved, and the Laplace operator A on 1-form of M is defined by non-linear connection and its curvature tensor. After proving the maximum principle theorem of Hopf-Bochner on M, the Bochner type vanishing theorem of Killing vectors and harmonic 1-form are obtained.
基金supported in part by NNSFC(11271381 and 11431015)supported in part by the Joint NSFC-RGC Research Fund,N-CityU 102/12+1 种基金supported in part by the Program for Liaoning Excellent Talents in University(LJQ2013124)the Fundamental Research Fund for the Central Universities
文摘The paper aims to estimate the thickness of the boundary layer for the planar MHD system with vanishing shear viscosity μ. Under some conditions on the initial and boundary data, we show that the thickness is of the order √μ|lnμ|. Note that this estimate holds also for the Navier-Stokes system so that it extends the previous works even without the magnetic effect.
基金Zhao was supported by a scholarship from the China Scholarship Council,Li was partially supported by NSF of China(11731005)Cao was partially supported by NSF of China(11901264).
文摘This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the free boundary problem studied by Kim et al.(An SIR epidemic model with free boundary.Nonlinear Anal RWA,2013,14:1992-2001).We first prove that this problem has a unique solution defined for all time,and then we give sufficient conditions for the disease vanishing and spreading.Our result shows that the disease will not spread if the basic reproduction number R_(0)<1,or the initial infected area h_(0),expanding ability μ and the initial datum S_(0) are all small enough when 1<R_(0)<1+d/μ_(2)+α.Furthermore,we show that if 1<R_(0)<1+d/μ_(2)+α,the disease will spread when h_(0) is large enough or h_(0) is small but μ is large enough.It is expected that the disease will always spread when R_(0)≥1+d/μ_(2)+α which is different from the local model.
基金Yachun Li’s research was supported partly by National Natural Science Foundation of China (10571120,10971135)the Program for New Century Excellent Talents of Chinese Ministry of Education (NCET-07-0546)+3 种基金Shanghai Shuguang Project 06SG11Zhigang Wang’s research was supported partly by Shanghai Jiao Tong University Innovation Fund For Postgraduates (AE071202)the University Young Teacher Sciences Foundation of Anhui Province (2010SQRL145)the Quality Project Found of Fuyang Normal College (2010JPKC07)
文摘The aim of this paper is to prove the well-posedness(existence and uniqueness) of the L p entropy solution to the homogeneous Dirichlet problems for the anisotropic degenerate parabolic-hyperbolic equations with L p initial value.We use the device of doubling variables and some technical analysis to prove the uniqueness result.Moreover we can prove that the L p entropy solution can be obtained as the limit of solutions of the corresponding regularized equations of nondegenerate parabolic type.
基金Supported by the Youth Science Fund for Disaster Prevention and Reduction(201207)Supported by the Teachers’Scientific Research Fund of China Earthquake Administration(20140109)
文摘In this paper, we show the asymptotic limit for the 3D Boussinesq system with zero viscosity limit or zero diffusivity limit. By the classical energy method, we prove that as viscosity(or diffusivity) coefficient goes to zero the solutions of the fully viscous equations converges to those of zero viscosity(or zero diffusivity) equations, which extend the previous results on the asymptotic limit under the conditions of the zero parameter(zero viscosity ν = 0 or zero diffusivity η = 0) in 2D case separately.
基金Supported by the National Natural Science Foun-dation of China(10101018)
文摘The lifting scheme is a custom design construclion of Biorthogonal wavelets, a fast and efficient method to realize wavelet transform,which provides a wider range of application and efficiently reduces the computing time with its particular frame. This paper aims at introducing the second generation wavelets, begins with traditional Mallat algorithms, illustrates the lifting scheme and brings out the detail steps in the construction of Biorthogonal wavelets. Because of isolating the degrees of freedom remaining the biorthogonality relations, we can fully control over the lifting operators to design the wavelet for a particular application, such as increasing the number of the vanishing moments.
基金funded by The Legacy Heritage Bio-Medical Program of the Israel Science Foundation(grant No.1629/13)
文摘Vanishing white matter (VWM) disease - a disease of the cytosolic translation machinery: VWM is a recessive genet- ic neurodegenerative disease caused by mutations in any of the five genes encoding the subunits of translation initiation factor 2B (eIF2B) (Leegwater et al., 2001; OMIM 306896).