Simultaneous Determination of Fluorescein, Rhodamine 6G and Rhodamine B in Turbid Solution by Polarization Variable-Angle Synchronous Fluorescence Spectrometry

Polarization variable-angle synchronous fluorescence spectrometry was proposed to determine samples in turbid solution. A mixture of fluorescein, rhodamine 6G and rhodamine B was used to evaluate the technique. The background caused by scattering light was decreased remarkably. The limits of detection were 0.6 ng/ml for fluorescein, 2.3 ng/ml for rhodamine 6G and 4.1 ng/ml for rhodamine B, respectively.

REVERSE VARIABLE-ANGLE SYNCHRONOUS SPECTROFLUORIMETRY FOR RAPID SIMULTANEOUS DETERMINATION OF CHLOROPHYLL A AND CHLOROPHYLL B

Rapid simultaneous determination of chlorophyll a and chlorophyll b by reverse variable-angle synchronous spectrofluorimetry has been studied on a laboratory-constructed microcomputer-controlled versatile spectrofluorimeter.A method in estimation of scan parameters for the determination of two-component system by variable-angle synchronous spectrofluorimetry has been suggested

Efficacy of 25% dextrose versus breast milk on pain and duration of cry during heel prick in neonates: A systematic review and meta-analysis

Neonates,especially admitted to neonatal intensive care unit,frequently need various medical interventions in their early days.A common procedure is the heel prick for blood sampling.Although necessary for diagnosis,this procedure can be stressful for neonates,causing pain,extended crying,and discomfort.Reducing distress in neonates during such procedures is important for the well‐being of neonates and the satisfaction of caregivers and healthcare providers.Therefore,this review aims to identify and compare the efficacy of 25%dextrose and breast milk on pain and duration of cry among neonates during heel-lance.As part of its review process,the article examined widely used databases,including PubMed,EMBASE,Cochrane,Academia,and Google Scholar.For the meta-analysis,the authors utilized RevMan 5.4.All eligible trials were analyzed using the Cochrane Risk of Bias Tool to assess the quality of the included studies and evaluate the risk of bias.Out of 131 studies reviewed,seven studies were included in meta-analysis of pain,and four studies were included in duration of cry.The results show that 25%dextrose is more effective to reduce pain among neonates during minor invasive procedure like heel prick(P<0.00001),whereas both interventions are effective in the reduction of crying duration.This review highlights that dextrose is more effective in reducing pain in comparison to breast milk.However,additional well-designed studies with larger sample sizes and extended follow-up periods are needed to validate and build upon the current findings.Hence,this review underscores the importance of utilizing effective pain management strategies,such as 25%dextrose,to enhance neonatal care and improve the overall well-being of newborns during invasive procedures.

LNG船舶HEEL的应用和管理

HEEL(底脚货)的应用和管理是LNG船舶运输的一个极为重要的方面。HEEL担负着多项使命,它既是货舱冷却的冷剂,又是船舶燃料,又是货物。正确地认识、应用和管理HEEL,有助于LNG船舶安全、稳定和可靠的运输。

Biomechanical evaluation of heel elevation on load transfer——experimental measurement and finite element analysis

In spite of ill-effects of high heel shoes, they are widely used for women. Hence, it is essential to understand the load transfer biomechanics in order to design better fit and comfortable shoes. In this study, both experimental measurement and finite element analysis were used to evaluate the biomechanical effects of heel height on foot load transfer. A controlled experiment was conducted using custom-designed platforms. Under different weight-bearing conditions, peak plantar pressure, contact area and center of pressure were analyzed. A three-dimensional finite element foot model was used to simulate the high-heel support and to predict the internal stress distributions and deformations for different heel heights. Results from both experiment and model indicated that heel elevations had significant effects on all variables. When heel elevation increased, the center of pressure shifted from the midfoot region to the forefoot region, the contact area was reduced by 26% from 0 to 10.2 cm heel and the internal stress of foot bones increased. Prediction results also showed that the strain and total tension force of plantar fascia was minimum at 5.1 cm heel condition. This study helps to better understand the biomechanical behavior of foot, and to provide better suggestions for design parameters of high heeled shoes.

Calcaneal osteochondroma masquerading as plantar fasciitis: An approach to plantar heel pain-A case report and literature review

BACKGROUND Heel pain is a common orthopaedic complaint,and if left untreated can be a source of chronic morbidity.Accurate diagnosis can be challenging,owing to the complex anatomy and multiple pain generators present in the foot.We aim to share our clinical experience managing an unusual case of chronic heel pain secondary to osteochondroma.CASE SUMMARY A 41-year-old obese male who works as a porter presented with a long-standing history of left plantar heel pain.He was assessed to have point tenderness over the plantar insertion of the calcaneus as well as a positive Silfverski?ld test.He was treated for plantar fasciitis and tight gastrocnemius but failed conservative therapies as well as surgical intervention.Magnetic resonance imaging revealed the presence of a pedunculated bony protrusion over the plantar aspect of the calcaneus.The decision was made for excision of the osteochondroma,and the patient has been pain-free since.CONCLUSION Osteochondromas are rarely symptomatic in skeletally mature patients.While most are benign with a very low risk of malignant transformation,surgical excision can yield excellent results and significant pain relief in symptomatic patients.

Regional plantar foot pressure distributions on high-heeled shoes-shank curve effects

Forefoot pain is common in high-heeled shoe wearers due to the high pressure caused by the center of body mass moving forward and the increased arch height with heel elevation.Sufficient arch support could reduce the high pressure over forefoot.However,too much arch support could lead to abnormal foot alignment and pain over midfoot.Little information is reported on the relationship among plantar arch height,shank curve design and plantar pressure.This study aimed at quantifying the plantar arch height changes at different heel heights and investigating the effect of shank curve on plantar pressure distribution.The plantar arch height increased to（7.6±1.3） mm at heel height of 75 mm.The Chinese standard suggests the depth of last should be 8.5 mm for heel height of 75 mm.When a shank curve with higher depth of last（11 mm） was used,the peak pressure over forefoot further decreased in midstance phase,which might ease the forefoot problems,while the peak pressure over midfoot increased but not exceeded the discomfort pressure thresholds.To achieve a more ideal pressure distribution in high-heeled shoes,a higher than expected depth of last would be suggested that would not cause discomfort over midfoot.

Where Do We Stand on High Heels in 2018? An Audit

We present an audit of public awareness, freedom of choice and health behavior change relating to high heel wear subsequent to a major public awareness campaign in the summer of 2017. Substantial reductions in workplace high heel wear were found, whereby increasingly those who wear high heels regularly at work have freely chosen to do so, although certain issues of social expectations remain in certain sectors. Largely, freedom of choice has greatly increased in workplaces in line with increased public and employer awareness.? However, high heel wear has not substantially reduced in social settings, and progress has not been made with social expectation and explicit requirement to wear high heels at social events.

Pressure Ulcer Prevention: Effectiveness of Heel Off-Loading Methodologies

Skin integrity breakdown and pressure ulcer formation on the heel are predictable and preventable healthcare occurrences. By minimizing surface contact pressures that can cause heel capillary occlusion, heel off-loading devices help mitigate the risk of decubitus ulceration. The purpose of this study is to investigate the efficacy of six off-loading methods commonly used in clinical settings to decrease heel contact pressure. Pressure mapping is used to evaluate contact pressure at the heel for underweight, normal weight, and overweight simulations. Based upon averages across four trials, it is shown that all devices reduce heel contact pressure when compared to no off-load- ing. The PRUventor&#8482 boot exhibits significantly lower average pressure values than other off-load- ing strategies tested, suggesting that the PRUventor&#8482 is the most effective off-loading device. From the analysis of the experimental data and comparison to similar data for respective off-loading alternatives, it is concluded that the PRUventor&#8482 boot is an effective heel off-loading device for use in clinical settings.

为什么ACHILLESHEEL被译为“致命弱点”及TROJAN这个病毒名称从何而来

为了帮助大家学习一些有用的英语成语,本文介绍了“致命弱点”这条英语成语的出处,同时介绍了源于同一典故,我们又经常遇到的一个计算机病毒“木马”。

Heel pain caused by os subcalcis:A case report

BACKGROUND The accessory bones are common bone variations around the feet and ankles,which usually originate from nonunion of the secondary ossification center adjacent to the main bone mass,and most of them remain asymptomatic.Os subcalcis is an accessory bone at the plantar aspect of the calcaneus,which is located just posterior to the insertion of the plantar fascia.Focal bone formation at the calcaneal plantar pole with heel pain has rarely been reported.CASE SUMMARY A 55-year-old man presented to our clinic with left plantar heel pain and a progressive swelling for 8 years.X-ray,computer tomography and magnetic resonance imaging showed a large os subcalcison the plantar side of the calcaneus,located at the insertion of the plantar fascia.He underwent surgical excision of the lesion.Microscopically the bony trabeculae were intermingled with fat and covered with cartilage.CONCLUSION This is a rare case with accessory os subcalcis leading to heel pain.It highlights the awareness of os subcalcis and helps avoid future misdiagnosis of heel pain.

Calcified plaque: the Achilles' Heel of present computed tomography coronary angiography for the elderly?

Nine percent to 27% of cardiac catheterizations today showed either angiographic normal coronary arteries or minimal atherosclerosis. 1,2 Given the expense of cardiac catheterization and the desire to use this valuable resource for therapeutic rather than diagnostic purpose, there is a strong impetus to develop non-invasive means of accurately detecting significant coronary artery stenosis.……

Eighty Cases of Heel Bone Spikes Treated With Little Needle-Knife

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Study on the Effect of the Intervention on Traditional Chinese Medicine Negative Heel Shoes in Geriatric Orthopedics Patients

In the clinical practice of orthopedics,geriatric patients are prone to form and exhibit complex and diverse clinical complications during long-term bedridden treatment.This can result in poor survival rate and adverse final clinical outcomes.Hence,it is essential to select appropriate methods for nursing intervention and health-care support for long-term bedridden geriatric orthopedic patients.It is of great significance to support and guarantee patients to obtain the best clinical results.This article focuses on the topic of interventional health effects of traditional Chinese medicine negative-heeled shoes in orthopedic bedridden patients,and two specific aspects were selected for a brief explanation.

高跟鞋全掌中底硬度对青年女性行走过程中步态特征与稳定性的影响

为了减少长期穿着高跟鞋对女性足部健康产生的不利影响,研究选取40名青年女性穿着3双不同全掌中底硬度的高跟鞋,采用Footscan^(R)足底压力测量系统与RSscan^(R)测力台同步使用,对其自然行走时步态周期、足底压力中心轨迹以及峰值压力、峰值压强、压强-时间积分等足底动力学特征进行测试。结果显示:随着全掌中底硬度的降低,前掌着地时间变长,全掌着地时间变短,足部外翻程度明显减小,内翻程度明显变大。较低的中底硬度具有良好的缓冲性能和保护性能。研究对于提升高跟鞋穿着稳定性及舒适性具有重要的参考价值,可为制鞋行业在高跟鞋中底材质的选择与研发方面提供科学可靠的理论支持。

Identifying Achilles-heel roads in real-sized networks

Ensuring a minimum operational level of road networks in the presence of unexpected incidents is becoming a hot subject in academic circles as well as industry. To this end, it is important to understand the degree to which each single element of the network contributes to the operation and performance of a network. In other words, a road can become an ＂Achilles-heel＂ for the entire network if it is closed due to a simple incident. Such insight of the detrimental loss of the closure of the roads would help us to be more vigilant and prepared. In this study, we develop an index dubbed as Achilles-heel index to quantify detrimental loss of the closure of the respective roads. More precisely, the Achilles-heel index indicates how many drivers are affected by the closure of the respective roads （the number of affected drivers is also called travel demand coverage）. To this end,roads with maximum travel demand coverage are sorted as the most critical ones, for which a method known as ＂link analysis＂--is adopted. In an iterative process, first, a road with highest traffic volume is first labeled as ＂target link,＂ and second, a portion of travel demand which is captured by the target link is excluded from travel demand. For the next iteration, the trimmed travel demand is then assigned to the network where all links including the target links run on the initial travel times. The process carries on until all links are labeled. The proposed methodology is applied to a large- sized network of Winnipeg, Canada. The results shed light on also bottleneck points of the network which may warrant provision of additional capacity or parallel roads.

Barefoot and High-Heeled Gait: Changes in Muscles Activation Patterns

Most women like wearing high-heeled shoes for the benefit of sensuous attractiveness and self-esteem while musculoskeletal problems and gait patterns changes are often associated. The present study aimed to identify changes during the gait stance and swing phases in some lower limb muscles. In addition, abdominal muscle was included due to its importance in dynamic trunk stability, and lack of studies on the subject. Here, we found that the use of high-heeled shoes elicited not only the increasing of the electrical activity from the muscles involved in the gait cycle, but also altered the temporal sequence of their recruitment. As practical applications, these changes may be strategies to maintain stability and minimize risks of falling, but they are often associated to diseases. Women that use high-heeled shoes for prolonged time must apply specific muscle exercises to minimize its long-term effects.

Effect of Flat Heel-Toe Difference of a Card on Yarn Unevenness and Usual Faults

Effect of flat heel-toe difference (HTD) of a card on some parameters of yarn quality was studied by testing the yarn which was produced under different HTDs, doffer speed, and cylinder speed with yarn evenness tester of PT7000. The effect of HTD on yarn parameters was analyzed by using SPSS. The results show that HTD has significant influence on parameters of thickness fault and nep. As a whole, the HTDs of 0.42 and 0.56 mm are beneficial to improving yarn quality in comparison with the other HTDs.

A Prospective Single-Arm Investigation Assessing Performance of a Multifunctional Foot Cream in Subjects with Tinea Pedis Interdigitalis and Heel Cracks, Calluses and/or Dry Feet

This prospective, open-label, single-arm investigation evaluated the performance of a multifunctional foot cream used twice daily for 8 weeks in the combined treatment of mild/moderate tinea pedis interdigitalis (TPI) and heel cracks, calluses and/or dry feet in 46 adult subjects. All subjects showed reductions in the severity of symptoms of both TPI (53.7% reduction) and heel cracks, calluses and/or dry feet (51.6% reduction), beginning already after 2 weeks of treatment, with reduction continuation and improvement after 4 and 8 weeks of treatment. Negative mycological cultures were obtained post-treatment in 85.7% of subjects, while 35.7% of subjects also obtained mycological cure (negative mycological culture + negative KOH test). Post-treatment questionnaires showed improved quality of life, good treatment tolerability, easy use, and that 69% of subjects would recommend the product. The results reveal that the foot cream is safe and effective in the combined treatment of TPI and heel cracks, calluses and/or dry feet.

新型高速道岔结构研发及列车过岔安全性分析

为了减小尖轨对列车高速运行安全性的影响,研发了一种新型高速道岔转辙器结构。新型转辙器去掉了既有结构中的尖轨,全部采用标准60 kg/m钢轨的轨头断面;转辙轨一端固定,另一端可左右转动,从而实现转向。基于车辆-道岔耦合动力学理论,分别建立标准18号道岔、新型道岔模型以及CRH_(2)型车的单车模型;通过与标准道岔对比,分析列车侧逆向通过新型道岔的安全性。结果表明:与标准道岔相比,列车侧逆向通过新型道岔时,在转辙器区域脱轨系数由0.49降为0.32,降低34.69%;轮轨横向力峰值由40.24 kN降为26.51 kN,降低34.12%;轮轨垂向力峰值由90.71 kN降到84.66 kN,降低6.67%。列车通过新型道岔时轮重减载率在跟端轨缝位置出现突变,在转辙器区域优于标准道岔。